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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Fabrication and biological evaluation of 3D-printed calcium phosphate ceramic scaffolds with distinct macroporous geometries through digital light processing technology显示文摘Digital light processing(DLP)-based 3D printing technique holds promise in fabricating scaffolds with high precision.Here raw calcium phosphate(CaP)powders were modified by 5.5%monoalcohol ethoxylate phosphate(MAEP)to ensure high solid loading and low viscosity.The rheological tests found that photocurable slurries composed of 50wt%modified CaP powders and 2wt%toners were suitable for DLP printing.Based on geometric models designed by computer-aided design(CAD)system,three printed CaP ceramics with distinct macroporous structures were prepared,including simple cube,octet-truss and inverse face-centered cube(fcc),which presented the similar phase composition and microstructure,but the different macropore geometries.Inverse fcc group showed the highest porosity and compressive strength.The in vitro and in vivo biological evaluations were performed to compare the bioactivity of three printed CaP ceramics,and the traditional foamed ceramic was used as control.It suggested that all CaP ceramics exhibited good biocompatibility,as evidence by an even bone-like apatite layer formation on the surface,and the good cell proliferation and spreading.A mouse intramuscular implantation model found that all of CaP ceramics could induce ectopic bone formation,and foam group had the strongest osteoinduction,followed by inverse fcc,while cube and octet-truss had the weakest one.It indicated that macropore geometry was of great importance to affect the osteoinductivity of scaffolds,and spherical,concave macropores facilitated osteogenesis.These findings provide a strategy to design and fabricate high-performance orthopedic grafts with proper pore geometry and desired biological performance via DLP-based 3D printing technique. | Jing Wang Yitao Tang Quanle Cao Yonghao Wu Yitian Wang Bo Yuan Xiangfeng Li Yong Zhou Xuening Chen Xiangdong Zhu Chongqi Tu Xingdong Zhang | 2022 | Regenerative Biomaterials2022，9，1： | 2 |
| 3 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 4 | Graphene oxide coated three-dimensional printed biphasic calcium phosphate scaffold for angiogenic and osteogenic synergy in repairing critical-size bone defect显示文摘The custom-tailored medicine requires a developmental strategy that integrates excellent osteogene-sis with mechanical stability to enhance the reconstruction of the critical-size bone defect(CSBD)and the healing process in weight-bearing bone.We prepared three-dimensional(3D)printed biphasic cal-cium phosphate(BCP)scaffolds composited with nano-graphene oxide(GO).The biological effects of the GO/BCP composite scaffolds could induce the differentiation of rat bone marrow stem cells(BM-SCs)and the migration of human umbilical vein endothelial cells(HUVECs)for bone repair.The proper ratio of GO in the composite scaffold regulated the composites’surface roughness and hydrophilicity to a suitable range for the adhesion and proliferation of BMSCs and HUVECs.Besides,the GO/BCP composite scaffold increased osteogenesis and angiogenesis by activating BMP-2,RUNX-2,Smad1/4,and VEGF.The customized intramedullary nail combined with GO/BCP scaffold was applied to repair CSBD(2.0 cm in length)in a beagle femur model.This fixation strategy was confirmed by finite element analysis.In vivo,the results indicated that the custom-made internal fixation provided sufficient stability in the early stage,ensuring bone healing in a considerable mechanical environment.At 9 months postoperatively,longitudi-nal bony union and blood vessels in osteon were observed in the CSBD area with partial degradation in the 0.3%GO/BCP group.In the three-point bending test,the ultimate load of 0.3%GO/BCP group reached over 50%of the normal femur at 9 months after repair.These results showed a promising application of osteogenic GO/BCP scaffold and custom-made intramedullary nails in repairing CSBD of the beagle femur.This effective strategy could provide an option to treat the clinical CSBD in weight-bearing bones. | Yitian Wang Yonghao Wu Yuqi Zhang Xiangfeng Li Li Min Quanle Cao Yi Luo Xiao Yang Minxun Lu Yong Zhou Xiangdong Zhu Chongqi Tu Xingdong Zhang | 2023 | Journal of Materials Science & Technology2023，，14： | 1 |
| 5 | Secreted IL‐1α promotes T‐cell activation and expansion of CD11b+Gr1+ cells in carbon tetrachloride‐induced liver injury in mice显示文摘 | Dandan Lin Lei Lei Yinsheng Zhang Bo Hu Guangming Bao Yonghao Liu Yuan Song Chunliang Liu Yan Wu Lixiang Zhao Xiao Yu Haiyan Liu | 2015 | Eur. J. Immunol2015，，： | 1 |
| 6 | 916 MHz electromagnetic field exposure affects rat behavior and hippocampal neuronal discharge显示文摘Wistar rats were exposed to a 916 MHz,10 W/m2 mobile phone electromagnetic field for 6 hours a day,5 days a week.Average completion times in an eight-arm radial maze were longer in the exposed rats than control rats after 4-5 weeks of exposure.Error rates in the exposed rats were greater than the control rats at 6 weeks.Hippocampal neurons from the exposed rats showed irregular firing patterns during the experiment,and they exhibited decreased spiking activity 6-9 weeks compared with that after 2-5 weeks of exposure.These results indicate that 916 MHz electromagnetic fields influence learning and memory in rats during exposure,but long-term effects are not obvious. | Dongmei Hao Lei Yang Su Chen Yonghao Tian Shuicai Wu | 2012 | Neural Regeneration Research2012，7，19： | 0 |
| 7 | Efficient Photolytic Halogenation and Oxidation of Unactivated Alkyl sp3 C—H Bonds with Iodine(III)显示文摘A metal-free,green,and sustainable functionalization of unactivated alkyl sp3 C—H bonds is reported using iodine(III)as a feasible dehydrogenation agent under visible light or KBr,and alkyl chlorides,bromides,alcohols,and ketones could be constructed by addition of different coupling reagents.Cheap and safe iodobenzene diacetate was used to form a radical to activate the alkyl sp3 C—H bond in a highly efficient manner,which can construct different alkylation products by adding corresponding coupling reagents. | Hao Jia Nan Li Chunmei Tang Yajuan Wang Yonghao Xi Rongbao Liao Wei Xu Fufang Wu Xiaobao Shen Hongbin Zhai | 2024 | Chinese Journal of Chemistry2024，42，5： | 0 |
| 8 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 9 | Enhanced bone regenerative properties of calcium phosphate ceramic granules in rabbit posterolateral spinal fusion through a reduction of grain size显示文摘Osteoinductivity is a crucial factor to determine the success and efficiency of posterolateral spinal fusion(PLF)by employing calcium phosphate(Ca-P)bioceramics.In this study,three kinds of Ca-P ceramics with microscale to nanoscale gain size(BCP-control,BCP-micro and BCP-nano)were prepared and their physicochemical properties were characterized.BCP-nano had the spherical shape and nanoscale gain size,BCP-micro had the spherical shape and microscale gain size,and BCP-control(BAM®)had the irregular shape and microscale gain size.The obtained BCP-nano with specific nanotopography could well regulate in vitro protein adsorption and osteogenic differentiation of MC3T3 cells.In vivo rabbit PLF procedures further confirmed that nanotopography of BCP-nano might be responsible for the stronger bone regenerative ability comparing with BCP-micro and BCP-control.Collectedly,due to nanocrystal similarity with natural bone apatite,BCP-nano has excellent efficacy in guiding bone regeneration of PLF,and holds great potentials to become an alternative to standard bone grafts for future clinical applications. | Xiangfeng Li Quan Zhou Yonghao Wu Cong Feng Xi Yang Linnan Wang Yumei Xiao Kai Zhang Xiangdong Zhu Limin Liu Yueming Song Xingdong Zhang | 2022 | Bioactive Materials2022，7，5： | 0 |
| 10 | NIR-responsive Collagen-based Sponge Coated with Polydimethylsiloxane/Candle Soot for Oil-Water Separation显示文摘To fabricate an oil-water separation material that is rich in source,eco-friendly,and responsive,in this study,we successfully developed a collagen-based sponge for application to oil-water separation based on a green and facile strategy.In this design,widely-available collagen(COL)was used as the substrate:it was immersed in polydimethylsiloxane(PDMS)suspension with candle soot(CS)nanoparticles,followed by hot curing.The resultant sponge(CS/PDMS-COL)possessed good hydrophobicity with a water contact angle of 148.3°under a low PDMS concentration of 2%.The results from field emission scanning electron microscope,Fourier transform infrared spectrometer,X-ray photoelectron spectrometer,and X-ray diffractometry demonstrated the successful coating of CS and PDMS on the surface of COL substrate.The CS/PDMS-COL can adsorb eight oils,with the adsorption capacity for trichloromethane reaching 95 g/g.With benzene as the target adsorbent,the separation efficiency was maintained at no less than 95%even after recycling 20 times.CS/PDMS-COL was also used to separate oil-in-water emulsion.Moreover,the sponge killed bacteria effectively due to its excellent near-infrared photothermal responsiveness.This study provides new insight into the preparation of facile oil-water separation materials based on naturally occurring biomaterials effortlessly. | Min Zhang Chenchen Guo Yu Wang Yunlong Zhang Hui Wu Liulian Huang Yonghao Ni Cuicui Ding Lihui Chen | 2022 | Paper And Biomaterials2022，7，3： | 0 |
| 11 | Attack of Limestone Cement-based Material Exposed to Magnesium Sulfate Solution at Low Temperature显示文摘Limestone in cement could be a source of CO 3 2- needed for thaumasite formation which will result in thaumasite form of sulfate attack(TSA) probably. TSA has more deterioration than ettringite or gypsum form of sulfate attack because it targets the calcium silicate hydrates(C-S-H) which is the main binder phase in all Portland cement-based materials. By means of physical and mechanical property testing as well as erosion phases analysis, magnesium sulfate attack of cement-based material containing 35% limestone powder by mass at 5 ± 2 ℃ is investigated. The compressive strength and fl exural strength of mortar specimen immersed in MgSO 4 solution increase firstly, then decrease rapidly with the immersing age. Relative dynamic elastic modulus of mortar specimen changes in a phased process. After immersing in MgSO 4 solution for 15 weeks, the main erosion phases in paste specimen change from four phases compounds, three phases compounds to two phases compounds from surface to inside. Deterioration course of limestone cement-based material exposed to magnesium sulfate aggressive environment appears progressive damage layer by layer, and every layer probably suffers four stages, which are property strengthening stage, initial degradation stage, thaumasite formation stage and cementation loss stage, respectively. | 张风臣 WU Shengxing FANG Yonghao ZHOU Jikai LI Zhonghua | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，3： | 0 |
| 12 | Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019(COVID-19)显示文摘Introduction Coronavirus disease 2019(COVID-19),a disease caused by severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2),is highly contagious[1]and has developed into a global pan-demic.Up to July 1,2022,COVID-19 has affected>200 coun-tries and regions across the globe and caused 545,226,550 con-firmed cases and 6334,728 deaths,[2]seriously compromising human life,public properties. | You Shang Jianfeng Wu Jinglun Liu Yun Long Jianfeng Xie Dong Zhang Bo Hu Yuan Zong Xuelian Liao Xiuling Shang Renyu Ding Kai Kang Jiao Liu Aijun Pan Yonghao Xu Changsong Wang Qianghong Xu Xijing Zhang Jicheng Zhang Ling Liu Jiancheng Zhang Yi Yang Kaijiang Yu Xiangdong Guan Dechang Chen Chinese Society of Critical Care Medicine,Chinese Medical Association | 2022 | Journal of Intensive Medicine2022，2，4： | 0 |
| 13 | Venovenous extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome:A comparative cohort study in China显示文摘Background Venovenous extracorporeal membrane oxygenation(VV-ECMO)has been demonstrated to be effective in treating patients with virus-induced acute respiratory distress syndrome(ARDS).However,whether the management of ECMO is different in treating H1N1 influenza and coronavirus disease 2019(COVID-19)-associated ARDS patients remains unknown.Methods This is a retrospective cohort study.We included 12 VV-ECMO-supported COVID-19 patients admitted to The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Eighth People's Hospital,and Wuhan Union Hospital West Campus between January 23 and March 31,2020.We retrospectively included VV-ECMO-supported patients with COVID-19 and H1N1 influenza-associated ARDS.Clinical characteristics,respiratory mechanics including plateau pressure,driving pressure,mechanical power,ventilatory ratio(VR)and lung compliance,and outcomes were compared.Results Data from 25 patients with COVID-19(n=12)and H1N1(n=13)associated ARDS who had received ECMO support were analyzed.COVID-19 patients were older than H1N1 influenza patients(P=0.004).The partial pressure of arterial carbon dioxide(PaCO_(2))and VR before ECMO initiation were significantly higher in COVID-19 patients than in H1N1 influenza patients(P<0.001 and P=0.004,respectively).COVID-19 patients showed increased plateau and driving pressure compared with H1N1 subjects(P=0.013 and P=0.018,respectively).Patients with COVID-19 remained longer on ECMO support than did H1N1 influenza patients(P=0.015).COVID-19 patients who required ECMO support also had fewer intensive care unit and ventilator-free days than H1N1.Conclusions Compared with H1N1 influenza patients,COVID-19 patients were older and presented with increased PaCO_(2) and VR values before ECMO initiation.The differences between ARDS patients with COVID-19 and influenza on VV-ECMO detailed herein could be helpful for obtaining a better understanding of COVID-19 and for better clinical management. | Yonghao Xu Yin Xi Shuijiang Cai Yuheng Yu Sibei Chen Weijie Guan Weibo Liang Hongkai Wu Weiqun He Xilong Deng Yuanda Xu Rong Zhang Manshu Li Jieyi Pan Zhenting Liang Ya Wang Shaofeng Kong Xiaoqing Liu Zheng Lv Yimin Li | 2023 | Journal of Intensive Medicine2023，3，4： | 0 |
| 14 | Review and prospect of immune checkpoint blockade therapy represented by PD-1/PD-L1 in the treatment of clear cell renal cell carcinoma显示文摘As a common tumor of the urinary system,the morbidity and mortality related to renal carcinoma,are increasing annually.Clear cell renal cell carcinoma(CCRCC)is the most common subtype of renal cell carcinoma,accounting for approximately 75%of the total number of patients with renal cell carcinoma.Currently,the clinical treatment of ccRCC involves targeted therapy,immunotherapy,and a combination of the two.In immunotherapy,PD-1/PD-L1 blocking of activated T cells to kill cancer cells is the most common treatment.However,as treatment progresses,some patients gradually develop resistance to immunotherapy.Meanwhile,other patients experience great side effects after immunotherapy,resulting in a survival status far lower than the expected survival rate.Based on these clinical problems,many researchers have been working on the improvement of tumor immunotherapy in recent years and have accumulated numerous research results.We hope to find a more suitable direction for future immunotherapy for ccRCC by combining these results and the latest research progress. | WENFEI GE SHIYAN SONG XIAOCHEN QI FENG CHEN XIANGYU CHE YONGHAO SUN JIN WANG XIAOWEI LI NANA LIU QIFEI WANG GUANGZHEN WU | 2023 | Oncology Research2023，31，3： | 0 |
| 15 | Mn-doping induced electronic modulation and rich oxygen vacancies on vertically grown NiFe2O4 nanosheet array for synergistically triggering oxygen evolution reaction显示文摘Large-scale electrolysis of water to produce high-purity hydrogen is one of the effective ways to solve the energy crisis and environmental pollution problems.However,efficient,cheap and stable catalysts are one of the bottlenecks for industrial application in water splitting.Herein,a facile one-step hydrothermal process was applied to fabricate Mn-doped nickel ferrite nanosheets(Mn-NiFe_(2)O_(4))which shown a low overpotential of 200 mV at 50 mA·cm^(-2)and a small Tafel slope of 47 mV·dec^(-1),together with a prominent turnover frequency(TOF)value(0.14 s^(-1))and robust stability.The in-situ UV-vis spectroscopy unveiled the surface reconstruction to generate NiOOH as active sites during oxygen evolution reaction(OER).The excellent electrocatalytic activity of Mn-NiFe_(2)O_(4)is attributed to the vertically grown nanosheets for exposure more active sites,rich oxygen vacancies,and the hybridization between Ni 3d and O 2p orbitals caused by Mn doping.This work should provide a facile strategy by Mn-doping to simultaneously engineer oxygen vacancies and electronic structure for synergistically triggering oxygen evolution reaction. | Yonghao Gan Meilin Cui Xiaoping Dai Ying Ye Fei Nie Ziteng Ren Xueli Yin Baoqiang Wu Yihua Cao Run Cai Xin Zhang | 2022 | Nano Research2022，15，5： | 0 |
| 16 | Expert consensus on the diagnosis and treatment of severe and critical coronavirus disease 2019显示文摘This consensus focuses on severe and critical coronavi-rus disease 2019(COVID-19)mainly based on the consideration that mortality of severe and critical cases is higher than mild and mo derate cases of COVID-19.Severe patients usually developed dyspnea and/or hypoxemia in a short period of time,and in some cases progressively developed respiratory failure,septic shock,coagulation disorders,and multi-organ dysfunction. | You Shang Jianfeng Wu Jinglun Liu Yun Long Jianfeng Xie Dong Zhang Bo Hu Yuan Zong Xuelian Liao Xiuling Shang Renyu Ding Kai Kang Jiao Liu Ajun Pan Yonghao Xu Changsong Wang Qianghong Xu Xjing Zhang Jicheng Zhang Ling Liu Jiancheng Zhang Yi Yang Kajiang Yu Xiangdong Guan Dechang Chen Chinese Society of Critical Care Medicine Chinese Medical Association | 2022 | Chinese Medical Journal2022，135，16： | 0 |
| 17 | A quantitative study on source rocks in the western Leidong depression, northern South China Sea显示文摘The Leidong depression is one of the secondary tectonic units and the least explored part of the Beibu Gulf Basin,northern South China Sea.Exploration activities in the basin reveal that the Middle Eocene deposition was controlled by NE-SW-striking faults and the second member of the Eocene Liushagang Formation(LII)consists of high-quality source rocks.The nature and origin of this depression has remained enigmatic due to the complex fault structures as compared to those in other basins.It is important to identify whether LII occurs in the Leidong depression in the context of exploration.Here we analyze available geological,seismic,and drilling data of the depression and the controlling factors among faults,deposition,lithology,and hydrocarbon distribution in the basin.Measures such as stress fracture analysis,fault growth index analysis,and sedimentary strata characterization were used to construct an Eocene sedimentary model controlled by NW-SE striking faults.The model with integrated seismic profile characteristics comparison and velocity analysis results was then used to determine whether the Eocene strata in the west of the depression contain the high-quality source rocks that are widely distributed elsewhere in the basin.Finally,calculations were performed to quantify the intensity of hydrocarbon generation and amount of hydrocarbon generated in the depression based on available data of the source rocks,including their distribution and thickness.The results confirmed the assumption that the Middle Eocene strata in the Leidong depression were controlled by NW-SE strike-slip faults and contain high-quality LII source rocks,thus providing an important foundation for future exploration. | Tao Wu Lie Li Wentuo Li Yonghao Gai Yu Qiu Guangchao Pan Lin Chen | 2021 | Energy Geoscience2021，2，1： | 0 |
| 18 | Identification and characterization of slime-producing microorganisms in papermaking water loops using emulsion polymerase chain reaction techniques显示文摘Slime formation on paper machines is a critical issue that can substantially impact the quantity and quality of paper production.This problem is caused by the growth of an abundant and diverse amount of bacteria.Through the application of emulsion polymerase chain reaction(emPCR),the bacterial diversity was analyzed on paper machines and more operational taxonomic units(OTUs)were obtained.Eleven types of bacterial phyla were found that have been previously identified,including Proteobacteria(α-,β-,γ-,ε-,andφ-),Bacteroidetes,Firmicutes,Cyanobacteria,Verrucomicrobia,Actinobacteria,Spirochaetes,Chloroflexi,Deinococcus-Thermus,and Armatimonadetes.Furthermore,for the first time,there were representatives of the phyla Lentisphaerae found on paper machines.This study revealed the wide bacterial diversities of slime found on paper machines in China,which was also similar to other industrial processes. | Liuxin Shi Gang Shi Rongxia ZhuGe Qiang Cheng Fangfang Wu Yonghao Ni | 2018 | Journal of Bioresources and Bioproducts2018，3，3： | 0 |
| 19 | Identification and validation of cardiac nonconserved human-specific enhancers显示文摘Congenital heart disease(CHD)is one of the most common causes of neonatal mortality.The worldwide morbidity of CHD is 9.410%o,while the proportion of CHD patients who are reported to carry mutations in coding regions is<50%.Enhancers play an important role in the spatio-temporal expression of target genes,and a lot of related variations are associated with CHD.There are conserved and nonconserved enhancers. | Yawen Zhang Yiting Gui Xudong Chen Feng Wang Fang Wu Youhua Wang Xu Wang Yonghao Gui Qiang Li | 2023 | Genes & Diseases2023，10，1： | 0 |
| 20 | Event-based control for piecewise-affine systems subject to actuator saturation显示文摘We deal with event-triggered Hoo controller design for discrete-time piecewise-affine systems subject to actuator saturation.By considering saturation information,a novel event-triggered strategy is proposed to conserve communication resources.A linear matrix inequality based condition is derived based on a piecewise Lyapunov function.This condition guarantees the stability of the closed-loop system with a certain Hoo performance index and reduces the number of transmitted signals.Numerical examples are given to show the efficiency of our method. | Yonghao JIANG Wei WU Xuyang LOU Zhengxian JIANG Baotong CUI | 2021 | Frontiers of Information Technology & Electronic Engineering2021，22，5： | 0 |
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