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9篇 您的检索式:作者名="LI Minfei"
    题名 作者 年代 出处 被引量
1Computer-assisted preoperative planning for proximal humeral fractures by minimally invasive plate osteosynthesis显示文摘Chen Yanxi Zhang Kun Qiang Minfei Li Haobo Dai Hao 2014Chinese Medical Journal2014,,18:9
2Neurofilament proteins in axonal regeneration and neurodegenerative diseases显示文摘Neurofilament protein is a component of the mature neuronal cytoskeleton, and it interacts with the zygosome, which is mediated by neurofilament-related proteins. Neurofilament protein regulates enzyme function and the structure of linker proteins. In addition, neurofilament gene expression plays an important role in nervous system development. Previous studies have shown that neurofilament gene transcriptional regulation is crucial for neurofilament protein expression, especially in axonal regeneration and degenerative diseases. Post-transcriptional regulation increased neurofilament protein gene transcription during axonal regeneration, ultimately resulting in a pattern of neurofilament protein expression. An expression imbalance of post-transcriptional regulatory proteins and other disorders could lead to amyotrophic lateral sclerosis or other neurodegenerative diseases. These findings indicated that after transcription, neurofilament protein regulated expression of related proteins and promoted regeneration of damaged axons, suggesting that regulation disorders could lead to neurodegenerative diseases.Haitao Wang Minfei Wu Chuanjun Zhan Enyuan Ma Maoguang Yang Xiaoyu Yang Yingpu Li 2012Neural Regeneration Research2012,7,8:8
3Microbial aerosol chemistry characteristics in highly polluted air显示文摘Aerosol chemistry is often studied without considering microbial involvements. Here, we investigated time-and size-resolved bacterial aerosol dynamics in air. Under high particulate matter(PM) polluted episodes, bacterial aerosols exhibited a viability of up to 50%–70% in the 0.56–1 μm size range, at which elevated levels of SO42-, NO3- and NH4+ were concurrently observed.Engineered or acclimated for both industrial use, bacteria such as Psychrobacter spp., Massilia spp., Acinetobacter lwoffii,Exiguobacteriumaurantiacum and Bacillusmegaterium were shown to have experienced massive abundance shifts in polluted air on early mornings and late afternoons, on which rapid new particle formation events were widely reported. Here, Psychrobacter spp. were shown to account for >96% abundance at a corresponding PM2.5 level of 208 μg/m3. These observed bacterial aerosol changes corresponded to the PM2.5 mass peak shift from 3.2–5.6 μm to the high viability size range of 0.56–1 μm. Additionally,elevated levels of soluble Na, Ca, Mg, K, Al, Fe and P elements, required for bacterial growth, were observed to co-occur with those significant bacterial aerosol structure shifts in the air. For particular time-resolved PM2.5 pollution episodes, Acinetobacter,Psychrobacter and Massilia were shown to alternate in dominating the time-resolved aerosol community structures. The results from a HYSPLIT trajectory model simulation suggested that air mass transport played a minor role in affecting the observed bacterial aerosol structure dynamics. All the data here suggested that airborne bacteria in the size range of 0.56–1 μm could be extensively involved in aerosol chemistry in highly polluted humid air.Ting Zhang Xinyue Li Minfei Wang Haoxuan Chen Maosheng Yao 2019Science China Chemistry2019,62,8:8
4Puerarin accelerates neural regeneration after sciatic nerve injury显示文摘Puerarin is a natural isoflavone isolated from plants of the genus Pueraria and functions as a protector against cerebral ischemia. We hypothesized that puerarin can be involved in the repair of peripheral nerve injuries. To test this hypothesis, doses of 10, 5, or 2.5 mg/kg per day puerarin(8-(β-D-Glucopyranosyl-7-hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) were injected intraperitoneally into mouse models of sciatic nerve injury. Puerarin at the middle and high doses significantly up-regulated the expression of growth-associated protein 43 in the L4–6 segments of the spinal cord from mice at 1, 2, and 4 weeks after modeling, and reduced the atrophy of the triceps surae on the affected side and promoted the regeneration of nerve fibers of the damaged spinal cord at 8 weeks after injury. We conclude that puerarin exerts an ongoing role to activate growth-associated protein 43 in the corresponding segment of the spinal cord after sciatic nerve injury, thus contributing to neural regeneration after sciatic nerve injuries.Minfei Wu Guanjie Zhao Xiaoyu Yang Chuangang Peng Jianwu Zhao Jun Liu Rui Li Zhongli Gao 2014Neural Regeneration Research2014,9,6:3
5Changes in the relationship between species richness and belowground biomass among grassland types and along environmental gradients in Xinjiang, Northwest China显示文摘The association between biodiversity and belowground biomass(BGB) remains a central debate in ecology.In this study, we compared the variations in species richness(SR) and BGB as well as their interaction in the top(0–20 cm), middle(20–50 cm) and deep(50–100 cm) soil depths among 8 grassland types(lowland meadow, temperate desert, temperate desert steppe, temperate steppe desert, temperate steppe, temperate meadow steppe, mountain meadow and alpine steppe) and along environmental gradients(elevation, energy condition(annual mean temperature(AMT) and potential evapotranspiration(PET)), and mean annual precipitation(MAP)) based on a 2011–2013 survey of 379 sites in Xinjiang, Northwest China.The SR and BGB varied among the grassland types.The alpine steppe had a medium level of SR but the highest BGB in the top soil depth, whereas the lowland meadow had the lowest SR but the highest BGB in the middle and deep soil depths.The SR and BGB in the different soil depths were tightly associated with elevation, MAP and energy condition;however, the particular forms of trends in SR and BGB depended on environmental factors and soil depths.The relationship between SR and BGB was unimodal in the top soil depth, but SR was positively related with BGB in the middle soil depth.Although elevation, MAP, energy condition and SR had significant effects on BGB, the variations in BGB in the top soil depth were mostly determined by elevation, and those in the middle and deep soil depths were mainly affected by energy condition.These findings highlight the importance of environmental factors in the regulations of SR and BGB as well as their interaction in the grasslands in Xinjiang.YANG Yuling LI Minfei MA Jingjing CHENG Junhui LIU Yunhua JIA Hongtao LI Ning WU Hongqi SUN Zongjiu FAN Yanmin SHENG Jiandong JIANG Ping'an 2019Journal of Arid Land2019,11,6:0
6In situ Reduction of Silver Nanoparticles on Chitosan Hybrid Copper Phosphate Nanoflowers for Highly Efficient Plasmonic Solar-driven Interfacial Water Evaporation显示文摘The development of water purification device using solar energy has received tremendous attention.Despite extensive progress,traditional photothermal conversion usually has a high cost and high environmental impact.To overcome this problem,we develop a low cost,durable and environmentally friendly solar evaporator.This bilayered evaporator is constructed with a thermal insulating polyvinylidene fluoride(PVDF)membrane as a bottom supporting layer and plasmonic silver nanoparticles decorated miero-sized hybrid flower(Ag/MF)as a top light-to-heat conversion layer.Compared with the sample with a flat silver film,the two-tier Ag/MF has a plasmonic enrichment property and high efficiency in converting the solar light to hcat as cach flower can gencrate a microscale hotspot by enriching the absorbed solar light.On the other hand,the PVDF membrane on the bottom with porous structure not only improves the mechanicalstability of the entire structure,but also maintains a stable water supply from the bulk water to the evaporation interface by capillarity and minimizes the thermal conduction.The combination of excellent water evaporation ability simple operation,and low cost of the production process imparts this type of plasmonic enhanced solar-driven interfacial water evaporator with promising prospects for potable water purification for point-of-use applications.Mei Zhang Wanghuai Xu Minfei Li Jiaqian Li Peng Wang Zuankai Wang 2021Journal of Bionic Engineering2021,18,1:0
7A common variant in AAK1 reduces risk of noise-induced hearing loss显示文摘Noise-induced hearing loss(NIHL)is one of the most common types of hearing loss and contributes to significant morbidity worldwide,as well as being the major cause of age-related hearing loss and tinnitus.The World Health Organization(WHO)estimates that 10%of the world's population is exposed to sound levels that could potentially cause NIHL[1].It has been widely accepted that NIHL is a multifactorial genetic disorder with estimated heritability of 36%to 40%[2].Ideally,identification of the modifying genetic variants would help protect individuals at high risk of NIHL.For decades,many geneticists have searched for genes that either predispose or protect from NIHL.Howeve r,the majority of genetic studies for NIHL were conducted in independent known candidate genes[3].Qixuan Wang Xueling Wang Tao Yang Lu Yang Huihui Liu Yihang Zheng Guixian Jiang Hongchao Liu Chenhui Huang Juan Chen Zhentao Wang Zhaoyan Wang Wei Zhao Jiannan Lin Xuejie Zhang Junbo Shi Kun Han Xingyu Le Yan Ren Yun Li Yingying Hong Wentao Shi Dongqi Cui Minfei Qian Jun Xu Xiaofei Zheng Yunge Gao Chen Li James Lin Zhiwu Huang Hao Wu 2023National Science Review2023,10,7:0
8Poly(C)-binding protein 2 positively regulates interferon downstream signaling显示文摘Host innate immunity protection against pathogen infection is universal in diverse species of invertebrates and vertebrates.Type I interferon(IFN-I)is induced by pathogen infection and secreted from the pathogen-infected host cells,and then binds to IFN-I receptors(IFNAR1 and IFNAR2)on the cell surface.This binding leads to the activation of the receptor-associated Janus-activated kinase 1(Jak1)and tyrosine kinase 2(Tyk2).Then the activated kinases phosphorylate the signal transducer and activator of transcription proteins 1 and 2(STAT1 and STAT2).Afterwards,the activated STAT1/2 complex combines with IFN-regulatory factor 9(IRF9)to form a complex that binds to the IFN-stimulated response elements on cellular DNA,which leads to the expression of the multiple IFN-stimulated genes(ISGs)[1,2].Due to the importance of JAK-STAT pathway to antiviral immunity,down-regulation of the IFN-I receptors will result in a disastrous damage of an IFN-I antiviral res-ponse.Therefore,maintaining IFNAR1 protein stability is a matter of cardinal importance for the enhancement of the antiviral efficacy of IFN-I.Chenxiao Huang Tao Jiang Minfei Xue Yanmei Li Tingting Feng Wen Pan Kezhen Wang Jianfeng Dai 2022Acta Biochimica et Biophysica Sinica2022,54,5:0
9Inverse-opal structured TiO_(2) regulating electrodeposition behavior to enable stable lithium metal electrodes显示文摘Lithium metal anode is almost the ultimate choice for high-energy density rechargeable batteries, but its uneven electrochemical dissolution-deposition characteristics lead to poor cycle stability and lithium dendrites safety problems. The fundamental solution to the problems is to interfere electrodeposition process of lithium metal so that it can be carried out reversibly and stably. In this work, an inverse-opal structured TiO2membrane with a thickness of only ~1 μm is designed to regulate the electrodeposition behavior of lithium metal, in which the ordered channels homogenize mass transfer process, the anatase TiO_(2)walls of the ion channels reduce desolvation barrier of solvated lithium-ions, and the spherical cavities with a diameter of ~300 nm confine migration of the adsorbed lithium atoms during electrocrystallization to diminish overpotential of lithium. These systematic effects cover and essentially change the whole process of electrodeposition of lithium metal and eliminate the possibility of lithium dendrite formation. The as-obtained lithium metal electrode delivers a Coulombic efficiency of 99.86% in the 100th cycle, and maintains a low deposition overpotential of 0.01 V for 800 h.Xuewen Wu Shaolun Cui Minfei Fei Sheng Liu Xueping Gao Guoran Li 2023Green Energy & Environment2023,8,6:0
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