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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | Diversity characterization and association analysis of agronomic traits in a Chinese peanut (Arachis hypogaea L.) mini-core collection显示文摘Association mapping is a powerful approach for exploring the molecular basis of phenotypic variations in plants.A peanut(Arachis hypogaea L.)mini-core collection in China comprising 298 accessions was genotyped using 109 simple sequence repeat(SSR)markers,which identified 554 SSR alleles and phenotyped for 15 agronomic traits in three different environments,exhibiting abundant genetic and phenotypic diversity within the panel.A model-based structure analysis assigned all accessions to three groups.Most of the accessions had the relative kinship of less than 0.05,indicating that there were no or weak relationships between accessions of the mini-core collection.For 15 agronomic traits in the peanut panel,generally the Q t K model exhibited the best performance to eliminate the false associated positives compared to the Q model and the general linear model-simple model.In total,89SSR alleles were identified to be associated with 15 agronomic traits of three environments by the Q t K model-based association analysis.Of these,eight alleles were repeatedly detected in two or three environments,and 15 alleles were commonly detected to be associated with multiple agronomic traits.Simple sequence repeat allelic effects confirmed significant differences between different genotypes of these repeatedly detected markers.Our results demonstrate the great potential of integrating the association analysis and marker-assisted breeding by utilizing the peanut mini-core collection. | Huifang Jiang Li Huang Xiaoping Ren Yuning Chen Xiaojing Zhou Youlin Xia Jiaquan Huang Yong Lei Liying Yan Liyun Wan Boshou Liao | 2014 | Journal of Integrative Plant Biology2014，56，2： | 14 |
| 3 | Overactive bladder symptom score to evaluate efficacy of solifenacin for the treatment of overactive bladder symptoms显示文摘 | Liu Ming Wang Jianye Yang Yong An Ruihua Wen Jianguo Guan Zhichen Zheng Shaobin Wang Dongwen Song Bo Liao Limin Guo Hongqian Xiao Jiaquan Sun Yinghao Shen Zhoujun Kong Chuize He Dalin Huang Yiran Wang Xiaofeng Zhang Xu Li Hanzhong Huang Jian Zhao Xiaokun Zeng Puqing Song Xishuang Ye Zhangqun | 2014 | Chinese Medical Journal2014，，2： | 7 |
| 4 | Fate of PM2.5-bound PAHs in Xiangyang, central China during 2018 Chinese spring festival: Influence of fireworks burning and air-mass transport显示文摘Variations of levels,possible source and air mass transmission were investigated for 16 USEPA priority-controlled PAHs in PM2.5 during 2018 Chinese Spring Festival(CSF)in Xiangyang City,central China which is the North-South pollutant airmass transport channel of China.Totally 37 samples were collected.Mass concentrations of 16 PAHs for the Pre–CSF day(Pre–CSFD),during the CSF day(CSFD)and after the CSF day(Af–CSFD)are 33.78±17.68 ng/m3,22.98±6.49 ng/m3,and 8.99±4.44 ng/m3,respectively.High resolution samples showed that 16 PAHs are higher in the morning(06:00–11:00)or afternoon(11:30–16:30),than those in the evening(17:00–22:00)and at night(22:30–05:30),whereas the result is reversed during the CSFD.Fireworks burning can obviously increase the mass concentration of PAHs.Air mass trajectory indicated that Xiangyang is a sink area of pollutants for northwest and southeast,and the sources of the northeast and southwest.The air mass only can be transmitted out through northeast and southwest.It is effective for improvement of air quality in Wuhan and Hunan to control fireworks emission in Henan and local areas.Fireworks burning was an important source for PAHs during CSFD,biomass,coal combustion,and traffic emission were the main sources of PAHs for Pre–CSFD and Af–CSFD periods.The health risk on the CSFD was higher than the acceptable levels,especially during the intensive fireworks burning,the risk value far exceed 1.0×10^-4,controlling burning fireworks is required. | Tianpeng Hu Yao Mao Weijie Liu Cheng Cheng Mingming Shi Zhanle Chen Qian Tian Jiaquan Zhang Shihua Qi Xinli Xing | 2020 | Journal of Environmental Sciences2020，32，11： | 6 |
| 5 | Application of focused laser differential interferometer to hypersonic boundary-layer instability study显示文摘Accurate prediction of hypersonic boundary-layer transition plays an important role in thermal protection system design of hypersonic vehicles.Restricted by the capability of spatial diagnostics for hypersonic boundary-layer study,quite a lot of problems of hypersonic boundary-layer transition,such as nonlinearity and receptivity,remain outstanding.This work reports the application of focused laser differential interferometer to instability wave development across hypersonic boundary-layer on a flared cone model.To begin with,the focused laser differential interferometer is designed and set up in a Mach number 6 hypersonic quiet wind tunnel with the focal point in the laminar boundary-layer of a 5 degree half-angle flared cone model.Afterwards,instability experiments are carried out by traversing the focal point throughout the hypersonic boundary-layer and the density fluctuation along the boundary-layer profile is measured and analyzed.The results show that three types of instability waves ranging from 10 k Hz to over 1 MHz are co-existing in the hypersonic boundary-layer,indicating the powerful capability of focused laser differential interferometer in dynamic response resolution for instability wave study in hypersonic flow regime;furthermore,quantitative analyses including spectra and bicoherence analysis of instability waves throughout the hypersonic boundary-layer for both cold and heated cone models are performed. | Tao YU Youde XIONG Jiaquan ZHAO Jie WU | 2021 | Chinese Journal of Aeronautics2021，34，5： | 4 |
| 6 | EXISTENCE OF POSITIVE ENTIRE SOLUTIONS FOR POLYHARMONIC EQUATIONS AND SYSTEMS显示文摘 | Liu Jiaquan Guo Yuxia Zhang Yajing | 2006 | Journal of Partial Differential Equations2006，19，3： | 4 |
| 7 | Carbon dioxide catalytic conversion to nano carbon material on the iron–nickel catalysts using CVD-IP method显示文摘The over-consumption of fossil fuels resulted in the large quantity emission of carbon dioxide(CO2), which was the main reason for the climate change and more extreme weathers. Hence, it is extremely pressing to explore efficient and sustainable approaches for the carbon-neutral pathway of CO2 utilization and recycling. In our recent works with this context, we developed successfully a novel 'chemical vapor deposition integrated process(CVD-IP)' technology to converting robustly CO2 into the value-added solid-form carbon materials.The monometallic Fe Ni0–Al2O3(FNi0) and bimetallic Fe Nix–Al2O3(FNi2, FNi4, FNi8 and FNi20) samples were synthesized and effective for this new approach. The catalyst labeled FNi8 gave the better performance, exhibited the single pass solid carbon yield of 30%. These results illustrated alternative promising cases for the CO2 capture utilization storage(CCUS), by means of the CO2 catalytic conversion into the solid-form nano carbon materials. | Jiaquan Hu Zhanglong Guo Wei Chu Le Li Tao Lin | 2015 | Journal of Energy Chemistry2015，24，5： | 4 |
| 8 | High throughput online sequential extraction of natural rare earth elements and determination by mass spectrometry显示文摘At the beginning of rare earth industry,several days are normally required for characterization of rare earth elements(REEs)fractionation in ore samples.Herein,rapid fractionation analysis of 15 REEs and accompanied metal(Fe,Mn,etc.)in ore samples has been achieved within 1 h using ICP-MS with a homemade device for online sequential solvent extraction.As a result,five fractionations for REEs occurrences,i.e.,water soluble,exchangeable,reducible,oxidizable and crystalline,have been identified,offering chemical insights which not only reveal the formation mechanism of REEs ores but also show great implications for guiding the exploitation and separation of REEs.In comparison with conventional methods,the present approach significantly shortened the analysis time(1 h vs.~80 h)and reduced the sample consumption(1.0 mg vs.5.0 g)with high recovery(>95%),providing a useful platform for the rapid quantitative fractionation analysis of REEs in complexed samples such as ore and fossils. | Jiaquan Xu Faliang Li Fei Xia Tenggao Zhu Debo Wu Konstantin Chingin Huanwen Chen | 2021 | Science China Chemistry2021，64，4： | 3 |
| 9 | Solid rocket motor propellant grain burnback simulation based on fast minimum distance function calculation and improved marching tetrahedron method显示文摘To efficiently compute arbitrary propellant grain evolution of the burning surface with uniform and non-uniform burning rate for solid rocket motor,a unified framework of burning surface regression simulation has been developed based on minimum distance function.In order to speed up the computation of the mini-mum distance between grid nodes of grain and the triangular mesh of burning surface,a fast distance querying method based on the equal size cube voxel structure was employed.An improved marching tetrahedron method based on piecewise linear approximation was carried out on second-order tetrahedral elements,achieved high-efficiency and adequate accuracy of burning surface extraction simultaneously.The cases of star grain,finocyl grain,and non-uniform tube grain were studied to verify the proposed method.The observed result indicates that the grain burnback computation method could realize the accurate simulation on unstructured tetrahedral mesh with a desirable performance on computational time. | Pengfei REN Hongbo WANG Guofeng ZHOU Jiani LI Qiang CAI Jiaquan YU Ya YUAN | 2021 | Chinese Journal of Aeronautics2021，34，4： | 2 |
| 10 | Effects of cardiotrophin-1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction显示文摘 | Ruixing Y Dezhai Y Jiaquan L | 2004 | J Med Invest2004，51，： | 1 |
| 11 | Cancer statistics, 2010 显示文摘 | Ahmedin J Rebecca S Jiaquan X | 2010 | CA Cancer J Clin2010，60，5： | 1 |
| 12 | Discovery of azabenzimidazole derivatives as potent, selective inhibitors of TBK1/IKKε kinases显示文摘 | Tao Wang Michael A. Block Scott Cowen Audrey M. Davies Erik Devereaux Lakshmaiah Gingipalli Jeffrey Johannes Nicholas A. Larsen Qibin Su Julie A. Tucker David Whitston Jiaquan Wu Hai-Jun Zhang Michael Zinda Claudio Chuaqui | 2012 | Bioorganic & Medicinal Chemistry Letters2012，，5： | 1 |
| 13 | Cancer Statistics,2010显示文摘 | Ahmedin Jemal DP Rebecca Siegel M Jiaquan Xu M | 2010 | Ca Cancer J Clin2010，60，5： | 1 |
| 14 | Lead dioxide as an alternative catalyst to platinum in microbial fuel cells 显示文摘 | Morris Jeffrey M Jin Song Wang Jiaquan | 2007 | Electrochemistry Communications2007，9，： | 1 |
| 15 | Investigationand optimization of waves motion behavior inpressure oscillating tube 显示文摘 | LIU Peiqi ZHU Yuqin ZHAO Jiaquan | 2013 | Experimental Thermaland Fluid Science2013，50，： | 1 |
| 16 | Effects of cardiotrophin- 1 on hemodynamics and cardiomyocyte apoptosis in rats with acute myocardial infarction 显示文摘 | RUIXING Y DEZHAI Y JIAQUAN L | 2004 | J Med Invest2004，51，12： | 1 |
| 17 | Lead dioxide as an ahernativecatalyst to platinum in microbial fuel cells 显示文摘 | MORRIS J M SONG Jin WANG Jiaquan | 2007 | Electrochemistry Communications2007，9，7： | 1 |
| 18 | Standardization of probability of earthquakes in seismic fortification 显示文摘 | Yan Jiaquan Chen Jiageng Gao Mengtan | 2000 | Recent Developments in World Seismology2000，，9： | 1 |
| 19 | Cancer statistics, 2010 显示文摘 | Ahmedin J Rebecca S Jiaquan X | 2010 | CA Cancer J Clin2010，60，5： | 1 |
| 20 | Cancer Statistics,2010显示文摘 | Ahmedin Jemal Rebecca Siegel Jiaquan Xu | 2010 | CA CANCER J CLIN2010，60，： | 1 |
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