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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | Chinese Stroke Association guidelines for clinical management of cerebrovascular disorders:executive summary and 2019 update of the management of high-risk population显示文摘Aim Cerebrovascular disease is the leading cause of death and disability in China,causing a huge burden among patients and their families.Hence,stroke prevention is critical,especially in the high-risk population.Here,we present the evidence-based guideline suitable for the Chinese population.Methods Literature search of PubMed and Cochrane library(from January 1964 to June 2019)was done.After thorough discussion among the writing group members,recommendations were listed and summarised.This guideline was reviewed and discussed by the fellow writing committees of the Chinese Stroke Association’s Stroke.Results This evidence-based guideline was written in three parts:controlling the risk factors of stroke,utilisation of antiplatelet agents and assessing the risks of first-ever stroke.All recommendations were listed along with the recommending classes and levels of evidence.Conclusions This guideline provides recommendations for primary prevention of cerebrovascular disease among high-risk population in China.Controlling related risk factors,appropriately using antiplatelet agents,assessing the risk of developing first-ever stroke should help reduce the rate of cerebrovascular disease in China. | Yilong Wang Shangrong Han Haiqiang Qin Huaguang Zheng Bin Jiang Yong Cao Yuan Gao Ling Guan Qian Jia Yong Jiang Yuming Jiao Shuya Li Yapeng Li Zixiao Li Wei Liu Xiaojuan Ru Dongling Sun Haixin Sun Penglian Wang Tingting Wang Lixia Zong Lei Guo Xuewei Xie Yuming Xu Yuyuan Xu Xiaomeng Yang Yingying Yang Mengyuan Zhou Wenzhi Wang Chinese Stroke Association Stroke Council Guideline Writing Committee | 2020 | Stroke & Vascular Neurology2020，5，3： | 11 |
| 3 | Effect of Strontium Addition to Platinum Catalyst for Propane Dehydrogenation显示文摘PtSnSr/HZSM-5 catalysts with different amounts of strontium were prepared by sequential impregnation method,and characterized by BET analysis,TEM,NH3-TPD,H2-TPR,TPO and TG techniques.The results showed that the addition of strontium could modify the characteristics and properties of both acid function and metal function of Pt-Sn-based catalysts.In this case,PtSnSr/HZSM-5 catalyst with an appropriate amount of Sr(1.2%) showed higher catalytic activity and lower amount of coke deposits than PtSn/HZSM-5 catalyst.However,excessive loading of Sr could facilitate the reduction of Sn,which was unfavorable to the reaction.Afterwards,1.0 m% of Na was added into the PtSnSr(1.2%)/HZSM-5 catalyst to improve the catalytic performance in propane dehydrogenation,and this catalyst displayed the best catalytic performance during our experiments.After having been subjected to reaction for 5h,the PtSnNa(1.0%)Sr(1.2%)/HZSM-5 catalyst had achieved a higher than 95% selectivity towards propene along with a corresponding propane conversion rate of 32.2%. | Huang Li Zhou Shijian Zhou Yuming Zhang Yiwei Zhang Shaobo Xu Jun | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，3： | 11 |
| 4 | The application and efficacy of stent place for Budd-Chiari syndrome显示文摘Objective To evaluate the application value and efficacy on stent place for Budd-Chiari syndrome(BCS). Methods From January 1990 to May 2017, 2228 patients with BCS were admitted to our institution. The mean age was 43.3 years. Stents were placed in inferior vena cava(IVC), hepatic vein(HV), or both after balloon dilation. During follow-up period, the patency of stent was evaluated by ultrasound regularly and the clinic sign was surveyed by letter, telephone or clinic visit. The restenosis of stent were treated with balloon dilatation and thrombolysis to restore the its function. Results IVC type was diagnosed in 1492 cases, HV type in 510 cases, and mixed type in 226 cases. Eighteen patients aborted treatment because of economic reasons, advanced liver cancer, severe scoliosis, or both bilateral iliac veins and total IVC occlusion. Among the other 2210 cases who underwent endovascular therapy, stents were implanted into IVC in 339 cases, HV in 97 cases, mixed type in 64 cases. The rate of restenosis in IVC stent was 11.50%(39/339). After repeat angioplasty, the long-term patency rate reached to 98.12%. The incidence of HV occlusion caused by IVC stent was 12.09%(n = 41). Restenosis occurred in 47 cases(48.45%) after HV stent placement. However, the 5-year patency rate was 91.75%(89/97) after repeat dilatation and stent re-implantation. The incidence of IVC obstruction caused by HV was 3.33%(3 cases). Conclusion IVC stent placement appears to be an effective treatment for the cases of IVC segmental occlusion, and at the same time, the stent has the dual role of compression and fixation of thrombus and support of lumen. The HV and accessory hepatic vein obstruction could happen when the IVC stent crossed these veins ostium. The incidence of the stent restenosis in the HV was higher than that in the IVC. | Maoheng Zu Hao Xu Yuming Gu Qingqiao Zhang Ning Wei Wei Xu Yanfeng Cui | 2018 | Journal of Interventional Medicine2018，1，3： | 7 |
| 5 | Spider web-like carbonized bacterial cellulose/MoSe_(2) nanocomposite with enhanced microwave attenuation performance and tunable absorption bands显示文摘It is essential to manufacture microwave absorbers with strong absorption as well as tunable absorption bands at a low filler content.However,it remains challenging for pure biomass material to reach this goal without loading other components.MoSe_(2),as a transition metal chalcogenide with semiconductor properties,has emerged as a potential microwave absorber filler.Herein,bacterial cellulose(BC)-derived carbon nanofibers/MoSe_(2) nanocomposite was fabricated and phosphoric acid was used to dope phosphorus in BC,in which MoSe_(2) microspheres were dropped on the BC network like a dew-covered spider web.This unique network structure enhances conductive loss and multiple reflections of the incident wave.The collocation of BC and MoSe_(2) is helpful to impedance match and introduces interfacial/dipolar polarization loss;moreover,the P-doping of BC helps to tune the absorption bands.Overall,the optimal reflection loss of undoped one reaches−53.33 dB with only 20 wt.%filler content,whose main absorption peaks focus on X-band.Interestingly,after the P-doping of BC,the main absorption peaks move to Ku-band and the optimal reflection loss gets stronger(−66.84 dB)with the same filler loading.Strong absorption and tunable absorption bands can be realized,and thus wide frequency range is covered.This work is expected to enlighten future exploration of biomass carbon materials on high-performance microwave absorption materials. | Zhengjian Xu Man He Yuming Zhou Shuangxi Nie Yongjuan Wang Yao Huo Yifan Kang Ruili Wang Ran Xu Hao Peng Xi Chen | 2021 | Nano Research2021，14，3： | 6 |
| 6 | MEASURING STRUCTURE COMPLEXITY OF UML CLASS DIAGRAMS显示文摘To provide system designer a valid measure to evaluate the structure complexityof class diagrams objectively, this letter first proposes a method to transform a class diagramsinto a weighted class dependence graph, then presents a structure complexity measure for classdiagrams based on entropy distance. | Zhou Yuming Xu Baowen (Dept. of Computer Science & Eng., Southeast Univ., Nanjing 210096) (State Key Laboratory of Software Engineering, Wuhan University, Wuhan 430072) (Jiangsu Key Lab. of Computer Info. Proc. Tech., Soochow Univ., Suzhou 215006) | 2003 | Journal of Electronics(China)2003，20，3： | 6 |
| 7 | Investigation on the fabrication of lightweight aggregate with acid-leaching tailings of vanadium-bearing stone coal minerals and red mud显示文摘Proper treatment of acidleaching tailings(ALTs)of vanadiumbearing stone coal minerals is of great urgency.One approach is adding it into the raw materials during the preparation of lightweight aggregate(LWA).But clay is always needed.In this paper,another solid waste,red mud,was mixed with ALTs as a source of flux components instead of clay.Evaluation of the physical characteristics,morphological structures,as well as crystal phases during the sintering process were investigated.When their mixtures with a proper ratio were sintered at 1080℃,a glassy phase with certain viscosity was formed,and the gases generated simultaneously were encapsulated by the melt.Finally,LWA with a onehour water absorption as low as 1.46%,a bulk density as low as 728.76 kgm 3 and a compressive strength as high as 10.77 MPa was fabricated. | Chunguang Song Hongling Zhang Yuming Dong Lili Pei Honghui Liu Junsheng Jiang Hongbin Xu | 2021 | Chinese Journal of Chemical Engineering2021，34，4： | 6 |
| 8 | Changing the strategy and culture of stroke awareness education in China: implementing Stroke 1-2-0显示文摘This project implemented the Stroke1-2-0 stroke awareness programme across China and investigated its impact over a 2-year period.We initiated the Stroke1-2-0 educational campaign and Stroke1-2-0 special task forces(STF)across the nation.Massive media coverage,community-based educational sessions with videos and other related materials and induction of Stroke1-2-0 STF were the major means of promotion.We delivered a survey at the end of 2016 and 2018 to evaluate the impact of our effort.A total of 3066 participants responded to the first survey in 2016,and 15207 participants responded in 2018 across China.The acceptance rate for Stroke1-2-0 versus FAST(an English-language stroke awareness tool)was 50.2%versus 19.1%in 2016,and changed significantly to 82.2%versus 8.0%in 2018(p<0.001).Stroke1-2-0 was well accepted by all ages and by people with different academic qualifications.Only 6.5%of survey respondents were aware that there was a therapeutic window for thrombolytic therapy in 2016,but this awareness increased significantly to 32.8%in 2018.Only 12.6%of people in 2016 indicated that they would send patients with stroke to the nearest hospital capable of performing thrombolytic therapy,but there was a nearly threefold increase(52.5%)in this number by 2018.More than 1000 major hospitals joined the Stroke1-2-0 STF,and more than 20000‘stroke warriors’have joined our stroke awareness improvement effort so far.Stroke1-2-0 stroke awareness programme is well-implemented and accepted,and is generating profound improvement in stroke awareness in China. | Jing Zhao Xutong Li Xiaochuan Liu Yuming Xu Jihong Xu Anding Xu Yongjun Wang Renyu Liu | 2020 | Stroke & Vascular Neurology2020，5，4： | 6 |
| 9 | Characteristics of vascular lesions in patients with posterior circulation infarction according to age and region of infarct显示文摘Patients with posterior circulation infarction underwent CT angiography and magnetic resonance angiography. Intracranial and extracranial vasculopathy was evaluated according to age group and location of stroke. Patients aged > 60 years and < 60 years had similar rates of vertebral artery dominance and vertebrobasilar artery developmental or origin anomalies. Vertebrobasilar artery stenosis or occlusion and tortuosity occurred more frequently in patients aged > 60 years than < 60 years. The rates of vertebrobasilar artery anomalies and tortuosity were high in patients with posterior circulation infarction. Vertebrobasilar artery tortuosity occurred more frequently in patients aged > 60 years, whereas vertebrobasilar artery developmental anomalies occurred with similar frequency in patients aged < 60 years and > 60 years. Patients with infarction of the brainstem or cerebellum were more likely to have vertebral artery stenosis or occlusion, basilar artery stenosis or occlusion, vertebral artery dominance or tortuosity, and basilar artery tortuosity, and patients with infarction of the thalamus, medial temporal, or occipital lobes were more likely to have stenosis or occlusion of the vertebral or basilar arteries. Vertebrobasilar artery tortuosity, vertebral artery dominance (hypoplasia), and congenital variations of the vertebrobasilar system may lead to posterior circulation infarction at different locations in different age groups. | Daopei Zhang Shuling Zhang Hongtao Zhang Yuming Xu | 2012 | Neural Regeneration Research2012，7，32： | 5 |
| 10 | Photocatalytic degradation of bisphenol A using an integrated system of a new gas-liquid-solid circulating fluidized bed reactor and micrometer Gd-doped TiO_2 particles显示文摘A new gas-liquid-solid circulating fluidized bed photocatalytic reactor (GLSCFBPR) with internally placed multi-layered UV lamps was developed. Micrometer Gd-TiO2 particles and commercial nanometer P25-TiO2 were chosen as the photocatalysts, and the hazardous substance bisphenol A (BPA) was chosen as the model pollutant to investigate the performance of this new photocatalytic system. The results showed that the photocatalytic degradation efficiency of the micrometer Gd-TiO2 particles was similar to that of the nanometer P-25 particles at their respective optimum dosage but the former could be easily separated out by gravity. After investigating the effects of process parameters on the photocatalytic BPA degradation, the response surface method (RSM) was further used for process optimization. The interactions among process parameters, i.e., TiO2 concentration, superficial gas velocity and superficial liquid velocity were discovered and a related analysis was carried out to explore the underlying mechanism. A quadratic mathematic model was established and performed satisfactorily when used for prediction. The optimum conditions for this new process were as follows: TiO2 concentration 4.5 g/L, superficial gas velocity 7.83 × 10-3 m/sec and superficial liquid velocity 8.65 × 10-3 m/sec. | Zhiliang Cheng Xuejun Quan Jinxin Xiang Yuming Huang Yunlan Xu | 2012 | Journal of Environmental Sciences2012，24，7： | 5 |
| 11 | The template preparation and characterization of three new shapes of titania nanometer-array systems显示文摘A two-step anodization process was used to prepare highly ordered porous anodic alu- mina template (PAA). The template method was combined with the sol-electrophoresis deposition and sol-gel method to synthesize three types of nano- meter-array systems. The titania nano-arrays have a high specific surface area. The sol-gel template method was also applied to prepare the rod-shaped titania nanowire-arrays. The diameter of titania nanometer-array is about 50 nm; the length is about 20 μm; and the distance of neighboring two nanowires is about 100 nm. Through controlling the pore depth of the template, the membrane with peri- odical modulating titania nanodots was prepared. The diameter of the nanodots on the membrane surface was about 75 nm and the dot distance was about 100 nm. Also a compact structure has been found on the back face of the membrane. The sol-electrophoresis template method was used to prepare the nanowire-array system with the shape of string of candied haws. The diameter of nanowires was about 75 nm and the length was about 20 μm. The periodic concave-convex structures were found in each nanowire and the shape looked like string of candied haws. The three types of nano-array systems have a high specific surface area. It can be predicted that this type of surface modulating array system will have new properties and effects that are different from those of common membranes, nanodots and nanowires. | TIAN Yuming XU Mingxia LIU Xiangzhi GE Lei | 2006 | Chinese Science Bulletin2006，51，12： | 4 |
| 12 | Methionine deficiency and its hydroxy analogue influence chicken intestinal 3-dimensional organoid development显示文摘Methionine and its hydroxy analogue(MHA)have been shown to benefit mouse intestinal regeneration.The intestinal organoid is a good model that directly reflects the impact of certain nutrients or chemicals on intestinal development.Here,we aimed to establish a chicken intestinal organoid culture method first and then use the model to explore the influence of methionine deficiency and MHA on intestinal organoid development.The results showed that 125-mm cell strainer exhibited the highest efficiency for chicken embryo crypt harvesting.We found that transforming growth factor-b inhibitor(A8301)supplementation promoted enterocyte differentiation at the expense of the proliferation of intestinal stem cells(ISC).The mitogen-activated protein kinase p38 inhibitor(SB202190)promoted intestinal organoid formation and enterocyte differentiation but suppressed the differentiation of enteroendocrine cells,goblet cells and Paneth cells.However,the suppression of enteroendocrine cell and Paneth cell differentiation by SB202190 was alleviated at the presence of A8301.The glycogen synthase kinase 3 inhibitor(CHIR99021),valproic acid(VPA)alone and their combination promoted chicken intestinal organoid formation and enterocyte differentiation at the expense of the expression of Paneth cells and goblet cells.Chicken serum significantly improved organoid formation,especially in the presence of A8301,SB202190,CHIR99021,and VPA,but inhibited the differentiation of Paneth cells and enteroendocrine cells.Chicken serum at a concentration of 0.25%meets the requirement of chicken intestinal organoid development,and the beneficial effect of chicken serum on chicken intestinal organoid culture could not be replaced by fetal bovine serum and insulin-like growth factor-1.Moreover,commercial mouse organoid culture medium supplemented with A8301,SB202190,CHIR99021,VPA,and chicken serum promotes chicken organoid budding.Based on the chicken intestinal organoid model,we found that methionine deficiency mimicked by cycloleucine suppressed organoid formation and organoid size,and this effect was reinforced with increased cycloleucine concentrations.Methionine hydroxy analogue promoted regeneration of ISC but decreased cell differentiation compared with the results obtained with L-methionine.In conclusion,our results provide a potentially excellent guideline for chicken intestinal organoid culture and insights into methionine function in crypt development. | Youli Wang Qihang Hou Yuqin Wu Yanwei Xu Yan Liu Jing Chen Lingling Xu Yuming Guo Shuai Gao Jianmin Yuan | 2022 | Animal Nutrition2022，，1： | 4 |
| 13 | Reducing Energy Loss and Morphology Optimization Manipulated by Molecular Geometry Engineering for Hetero-junction Organic Solar Cells显示文摘of main observation and conclusion Molecular geometry engineering is an efective strategy to control the micromorphology and molecularenergy level in organic photovoltaics(OPVs).Two novel copolymers based on alkysilyl-and chloride-functionalied benzodithiophene(BDT)were designed and synthesized for wide bandgap copolymer donor materials in OPVs.It was found that the two copolymers exhited distinctly different proper-ties in active layer when blended with fulerene-fre acceptor T-4.The chloride-functionalited copolymer PBDTCI-TZ2 with deeper molecular energy leveland better coplanar structure induced more ordered aggregation in blend flm.Thus,the device based on PBDTC-TZ exhibits better energy alinmentwith IT-4F and smallr radiative recombination.furthermore,the non-radiative recombination of PBDTCI-TZ.T-4F based device is about 45 mV lowerthan the PBDTS-TZ/T-4F based device,contributing to a lower enery loss(Ein,and a higher open-cicut voltage(Vc).As a resut,the devices based onthe blend of PBDTC-TZ2.IT-4F exhibit a high power conversion efficiency(PCE)of up to 12.2%with a high Vvoe of 0.837 Vv,higher than that of PBDTSi-TZ:IT-4F,of which the PCE is 11.2%with a Voc of 0.781V. | Guodong Xu Huan Rao Xunfan Liao Youdi Zhang Yuming Wang Zhi Xing Ting Hu Licheng Tan Lie Chen Yiwang Chen | 2020 | Chinese Journal of Chemistry2020，38，12： | 4 |
| 14 | Empirical analysis of network measures for predicting high severity software faults显示文摘Network measures are useful for predicting fault-prone modules. However, existing work has not distinguished faults according to their severity. In practice, high severity faults cause serious problems and require further attention. In this study, we explored the utility of network measures in high severity faultproneness prediction. We constructed software source code networks for four open-source projects by extracting the dependencies between modules. We then used univariate logistic regression to investigate the associations between each network measure and fault-proneness at a high severity level. We built multivariate prediction models to examine their explanatory ability for fault-proneness, as well as evaluated their predictive effectiveness compared to code metrics under forward-release and cross-project predictions. The results revealed the following:(1) most network measures are significantly related to high severity fault-proneness;(2) network measures generally have comparable explanatory abilities and predictive powers to those of code metrics; and(3) network measures are very unstable for cross-project predictions. These results indicate that network measures are of practical value in high severity fault-proneness prediction. | Lin CHEN Wanwangying MA Yuming ZHOU Lei XU Ziyuan WANG Zhifei CHEN Baowen XU | 2016 | Science China Earth Sciences2016，59，12： | 3 |
| 15 | Prognostic value of systemic immune- inflammation index in acute/subacute patients with cerebral venous sinus thrombosis显示文摘Objective To evaluate the prognosis values of systemic immune-inflammation index(SII)in non-chronic cerebral venous sinus thrombosis(CVST).Methods patients with CVST,admitted to the First Affiliated Hospital of Zhengzhou University,were retrospectively identified from January 2013 to December 2018.We selected patients in acute/subacute phase from database.Functional outcomes of patients were evaluated with the modified Rankin Scale(mRS)-mRS 3-6 as poor outcomes and mRS 6 as death.The overall survival time was defined as the date of onset to the date of death or last follow-up date.Survival analysis was described by the Kaplan-Meier curve and Cox regression analysis.Multivariate logistic regression analysis assessed the relationship between SII and poor functional outcome.The area under the Receiver Operating Curve curve(AUC)was estimated to evaluate the ability of SII in prediction.Results A total of 270 patients were included and their duration of follow-up was 22 months(6-66 months),of whom 31 patients had poor outcomes and 24 patients dead.Cox regression analysis showed that SII(HR=1.304,95%CI:1.101 to 1.703,p=0.001)was a predictor of death in non-chronic CVST.Patients with higher SII presented lower survival rates(p=0.003).The AUC of SII was 0.792(95%CI:0.695 to 0.888,p=0.040)with a sensitivity of 69.6%and specificity of 80.1%.Subgroups analysis demonstrated that SII was an important predictor of poor outcomes in male(OR=1.303,95%CI:1.102 to 1.501,p=0.011)and pregnancy/puerperium female(OR=1.407,95%CI:1.204 to 1.703,p=0.034).Conclusions SII was a potential predictor in the poor prognosis of patients with acute/subacute CVST,especially in male and pregnancy/puerperium female. | Shen Li Kai Liu Yuan Gao Lu Zhao Rui Zhang Hui Fang Yongli Tao Hongbing Liu Jiawei Zhao Zongping Xia Yuming Xu Bo Song | 2020 | Stroke & Vascular Neurology2020，5，4： | 3 |
| 16 | Three-Dimensional In Situ Stress-Field Simulations of Shale Gas Formations:A Case Study of the 5th Member of the Xujiahe Formation in the Xinchang Gas Field,West Sichuan Depression显示文摘This work established a geological model for the 5^(th) member of the Xujiahe Formation(X5 member) in the Xinchang gas field of the West Sichuan Depression based on the lithological, structural and depositional properties, as well as logging and well completion data and drill-core observations. Rock mechanical parameters were calculated according to rock mechanic experiments and rock mechanic interpretations from logging data. We also calculated the magnitudes and orientations of the in situ stresses based on acoustic emission tests, differential strain tests, fracturing behaviour and logging interpretations as well as anisotropy logging tests, borehole-breakout measurements and well-log data. Additionally, the present stress field of the X5 member was simulated using finite element numerical(FEM) simulation methods. The numerical simulation results indicate that the distributions of lithology and fractures are key factors that influence the present stress field. The stress field in the study area is discontinuous as a result of fractures and faults in the central and eastern areas. Stress is concentrated at the end sections and bends of faults, but dissipates with distance away from both sides of the faults. A longitudinal profile clearly demonstrates the zonality and continuity of the stress field and an increase with depth. The differential stress distribution is relatively uniform; however, large deviations occur in fracture zones. | LüJing ZHOU Wen XIE Runcheng SHAN Yuming ZHANG Chong XU Hao | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 3 |
| 17 | Effectiveness of intravenous r- tPA versus UK for acute ischaemic stroke: a nationwide prospective Chinese registry study显示文摘Background Intravenous recombinant tissue plasminogen activator(r-tPA)and urokinase(UK)are both recommended for the treatment of acute ischaemic stroke(AIS)in China,but with few comparative outcome data being available.We aimed to compare the outcomes of these two thrombolytic agents for the treatment of patients within 4.5 hours of onset of AIS in routine clinical practice in China.Methods A pre-planned,prospective,nationwide,multicentre,real-world registry of consecutive patients with AIS(age≥18 years)who received r-tPA or UK within 4.5 hours of symptom onset according to local decision-making and guideline recommendations during 2017-2019.The primary effectiveness outcome was the proportion of patients with an excellent functional outcome(defined by modified Rankin scale scores 0 to 1)at 90 days.The key safety endpoint was symptomatic intracranial haemorrhage according to standard definitions.Multivariable logistic regression was used for comparative analysis,with adjustment according to propensity scores to ensure balance in baseline characteristics.Results Overall,4130 patients with AIS were registered but 320 had incomplete or missing data,leaving 3810 with available data for analysis of whom 2666 received r-tPA(median dose 0.88(IQR 0.78-0.90)mg/kg)and 1144 received UK(1.71(1.43-2.00)×104 international unit per kilogram).There were several significant intergroup differences in patient characteristics:r-tPA patients were more educated,had less history of stroke,lower systolic blood pressure,greater neurological impairment and shorter treatment times from symptom onset than UK patients.However,in adjusted analysis,the frequency of excellent outcome(OR 1.18,95%CI 1.00 to 1.40,p=0.052)and symptomatic intracranial haemorrhage(OR 0.70,95%CI 0.33 to 1.47,p=0.344)were similar between groups.Conclusions UK may be as effective and carry a similar safety profile as r-tPA in treating mild to moderate AIS within guidelines in China.Registration http://gffzzd5593dd32ed44506hqcn9ocxf5vfq60cv.ffgz.tsg.suse.edu.cn identifier:NCT02854592. | Xinhong Wang Xiaoqiu Li Yuming Xu Runhui Li Qingcheng Yang Yong Zhao Fengyun Wang Baoying Sheng Runqing Wang Shaoyuan Chen Lihua Wang Liying Shen Xiaowen Hou Yu Cui Duolao Wang Bin Peng Craig S Anderson Huisheng Chen On behalf of INTRECIS Investigators | 2021 | Stroke & Vascular Neurology2021，6，4： | 2 |
| 18 | Influence of the Alkali Treatment of HZSM-5 Zeolite on Catalytic Performance of PtSn-Based Catalyst for Propane Dehydrogenation显示文摘The porous material ATZ with micro-mesopore hierarchical porosity was prepared by alkali treatment of parent HZSM-5 zeolite and applied for propane dehydrogenation. The zeolite samples were characterized by XRD, N2-physisorption, and NH 3-TPD analysis. The results showed that the alkali treatment can modify the physicochemical properties of HZSM-5 zeolite. In this case, the porous material ATZ showed larger external surface area with less acid sites as compared to the HZSM-5 zeolite. It was found out that the alkali treatment of HZSM-5 zeolite could promote the catalytic performance of PtSn/ATZ catalyst. The possible reason was ascribed to the low acidity of ATZ. Furthermore, the presence of mesopores could reduce the carbon deposits on the metallic surface, which was also favorable for the dehydrogenation reaction. | Huang Li Zhou Shijian Zhou Yuming Zhang Yiwei Xu Jun Wang Li | 2013 | China Petroleum Processing & Petrochemical Technology2013，15，2： | 2 |
| 19 | The chromosome-level Stevia genome provides insights into steviol glycoside biosynthesis显示文摘Stevia(Stevia rebaudiana Bertoni)is well known for its very sweet steviol glycosides(SGs)consisting of a common tetracyclic diterpenoid steviol backbone and a variable glycone.Steviol glycosides are 150–300 times sweeter than sucrose and are used as natural zero-calorie sweeteners.However,the most promising compounds are biosynthesized in small amounts.Based on Illumina,PacBio,and Hi-C sequencing,we constructed a chromosome-level assembly of Stevia covering 1416 Mb with a contig N50 value of 616.85 kb and a scaffold N50 value of 106.55 Mb.More than four-fifths of the Stevia genome consisted of repetitive elements.We annotated 44,143 high-confidence protein-coding genes in the high-quality genome.Genome evolution analysis suggested that Stevia and sunflower diverged~29.4 million years ago(Mya),shortly after the whole-genome duplication(WGD)event(WGD-2,~32.1 Mya)that occurred in their common ancestor.Comparative genomic analysis revealed that the expanded genes in Stevia were mainly enriched for biosynthesis of specialized metabolites,especially biosynthesis of terpenoid backbones,and for further oxidation and glycosylation of these compounds.We further identified all candidate genes involved in SG biosynthesis.Collectively,our current findings on the Stevia reference genome will be very helpful for dissecting the evolutionary history of Stevia and for discovering novel genes contributing to SG biosynthesis and other important agronomic traits in future breeding programs. | Xiaoyang Xu Haiyan Yuan Xiaqing Yu Suzhen Huang Yuming Sun Ting Zhang Qingquan Liu Haiying Tong Yongxia Zhang Yinjie Wang Chunxiao Liu Lei Wu Menglan Hou Yongheng Yang | 2021 | Horticulture Research2021，8，1： | 2 |
| 20 | Service-Oriented Wireless Multimedia Multicasting with Partial Frequency Reuse显示文摘Service-Oriented Architecture(SOA) is employed in a wide range of applications because it promises to expose computation-intensive tasks as services and combine them with new applications to accelerate their applications development process. For service-oriented multimedia applications, the performance of multicasting transmission services under multimedia traffic must be evaluated. Multiview Video(MVV) is a promising and emerging type of multimedia traffic that consists of multiple video streams, allows stream switching, and requires strict Quality-of-Service(Qo S). In this study, we investigated multicast transmission of MVV in wireless cellular networks with Partial Frequency Reuse(PFR) and focused on two challenging problems:(1) multicast group formation and(2) subchannel and power allocation. Initially, we propose a novel Content-based Partial frequency reuse Diversity Grouping(CPDG) scheme to allocate users to multicast groups on the basis of Partial frequency reuse Diversity(PD) in wireless networks with PFR. After group formation, an optimization problem for subchannel and power allocation is formulated to minimize network power consumption under Qo S constraint. Thereafter,the optimization problem is divided into two subproblems and solved using simplex method and Karush-KuhnTucker(KKT) condition. Finally, to solve the optimization problem, a suboptimal scheme referred to as Partial frequency reuse Diversity Based Energy-efficient Multicasting(PDEM) is proposed by dynamically allocating wireless resources under Qo S constraint. The simulation results show that the proposed PDEM scheme can achieve close-to-optimal performance. Moreover, mathematical analysis of the effect of PD on network performance can provide guidelines for optimization of multimedia traffic in multicasting-enabled wireless cellular networks with PFR. | Quanxin Zhao Liang Xu Yuming Mao Supeng Leng Geyong Min Jia Hu Noushin Najjari | 2016 | Tsinghua Science and Technology2016，21，6： | 2 |
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