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| 1 | Chimeric antigen receptor-engineered T-cell therapy for liver cancer显示文摘Background: Chimeric antigen receptor-engineered T-cell(CAR-T) therapy is a newly developed immunotherapy used in the treatment of cancers. Because CAR-T therapy has shown great success in treating CD19-positive hematological malignancies, its application has been explored in the treatment of solid tumors, such as liver cancer. In this review, we discuss the immune characteristics of liver cancer, the obstacles encountered during the application of CAR-T therapy, and preclinical and clinical progress in the use of CAR-T therapy in patients with liver cancer.Data sources: The data on CAR-T therapy related to liver cancers were collected by searching Pub Med and the Web of Science databases prior to December 2017 with the keywords 'chimeric antigen receptor','CAR-T', 'liver cancer', 'hepatocellular carcinoma', and 'solid tumor'. Additional articles were identified by manual search of references found in the primary articles. The data for clinical trials were collected by searching Clinical Trials.gov.Results: The liver has a tolerogenic nature in the intrahepatic milieu and its tumor microenvironment significantly affects tumor progression. The obstacles that reduce the efficacy of CAR-T therapy in solid tumors include a lack of specific tumor antigens, limited trafficking and penetration of CAR-T cells to tumor sites, and an immunosuppressive tumor microenvironment. To overcome these obstacles, several strategies have emerged. In addition, several strategies have been developed to manage the side effects of CAR-T, including enhancing the selectivity of CARs and controlling CAR-T activity. To date, no clinical trials of CAR-T therapy against HCC have been completed. However, preclinical studies in vitro and in vivo have shown potent antitumor efficacy. Glypican-3, mucin-1, epithelial cell adhesion molecule, carcinoembryonic antigen, and other targets are currently being studied.Conclusions: The application of CAR-T therapy for liver cancer is just beginning to be explored and more research is needed. However, we are optimistic that CAR-T therapy will offer a new approach for the treatment of liver cancers in the future. | Yang Chen Chang-Yong E Zhi-Wen Gong Shui Liu Zhen-Xiao Wang Yong-Sheng Yang Xue-Wen Zhang | 2018 | Hepatobiliary & Pancreatic Diseases International2018,17,4: | 16 |
| 2 | The Interactions among DWARF10,Auxin and Cytokinin Underlie Lateral Bud Outgrowth in Rice显示文摘Previous studies have shown that DWARF10(D10) is a rice ortholog of MAX4/RMS1/DAD1,encoding a carotenoid cleavage dioxygenase and functioning in strigolactones/strigolactone-derivatives(SL) biosynthesis.Here we use D10-RNA interference(RNAi) transgenic plants similar to d10 mutant in phenotypes to investigate the interactions among D10,auxin and cytokinin in regulating rice shoot branching.Auxin levels in node 1 of both decapitated D10-RNAi and wild type plants decreased significantly,showing that decapitation does reduce endogenous auxin concentration,but decapitation has no clear effects on auxin levels in node 2 of the same plants.This implies that node 1 may be the location where a possible interaction between auxin and D10 gene would be detected.D10 expression in node 1 is inhibited by decapitation,and this inhibition can be restored by exogenous auxin application,indicating that D10 may play an important role in auxin regulation of SL.The decreased expression of most OsPINs in shoot nodes of D10-RNAi plants may cause a reduced auxin transport capacity.Furthermore,effects of auxin treatment of decapitated plants on the expression of cytokinin biosynthetic genes suggest that D10 promotes cytokinin biosynthesis by reducing auxin levels.Besides,in D10-RNAi plants,decreased storage cytokinin levels in the shoot node may partly account for the increased active cytokinin contents,resulting in more tillering phenotypes. | Shuying Zhang Gang Li Jun Fang Weiqi Chen Haipai Jiang Junhuang Zou Xue Liu Xianfeng Zhao Xiaobing Li Chengcai Chu Qi Xie Xiangning Jiang Lihuang Zhu | 2010 | Journal of Integrative Plant Biology2010,52,7: | 14 |
| 3 | Arabidopsis trichome research sheds light on cotton fiber development mechanisms显示文摘Aerial surfaces of most land plants have epidermal hairs (trichomes).Both Arabidopsis thaliana trichomes and cotton fibers (seed hairs) are nonglandular hairs with unicellular structure.Here we out-line the recent progress on molecular dissection of Arabidopsis trichome development,including the transcription factors regulating trichome initiation,phytohormones influencing trichome density,and the cytoskeleton formation system governing trichome morphogenesis.There is increasing evidence showing that these processes also control cotton fiber production.As several cotton fiber genes are able to rescue the Arabidopsis trichome mutants,we discuss the conservation between Arabidopsis trichome and cotton fiber development. | GUAN XueYing YU Nan SHANGGUAN XiaoXia WANG Shui LU Shan WANG LingJian CHEN XiaoYa | 2007 | Chinese Science Bulletin2007,52,13: | 10 |
| 4 | Structural basis for the impact of phosphorylation on the activation of plant receptor-like kinase BAK1显示文摘 | Liming Yan Yuanyuan Ma Dan Liu Xiaochao Wei Yuna Sun Xiaoyue Chen Huadong Zhao Jingwen Zhou Zhiyong Wang Wenqing Shui Zhiyong Lou | 2012 | Cell Research2012,22,8: | 10 |
| 5 | Emission and Fixation of CO_2 from Soil System as Influenced by Long-Term Application of Organic Manure in Paddy Soils显示文摘The observations of 25-yr long-term experiment in Zhejiang paddy soils showed that the soil organic matter could increase continuously with applying organic manure, and the increase in rate enhanced along with the application rates of organic manure. By mathematical modeling, the soil organic matter increased by 22 kg when 1 t of fresh FYM was applied. The CO2 emission resulting from the mineralization of soil organic matter increased with the increase in the application rate of the organic manure as well as the increase in the root residues. It is expected that the CO2 emission will be at 10.04-21.61 t ha-1 yr-1 when 16.5-49.5 t ha-1 yr-1 of fresh FYM is applied. The soil organic carbon from mineralization and release of applied organic carbon (fresh FYM and root residues) will affect the CO2 concentration in the atmosphere. So, the higher the application rate of organic manure, the more is the fixed organic carbon. The CO2 fixation will be at 1.885-3.463 t ha-1 yr-1 when 16.5-49.5 t ha-1 yr-1 of fresh FYM is applied. Thus, the CO2 fixation will increase by 46.7 kg by applying 1 t fresh FYM. To apply organic manure continuously in rice fields may reduce the contribution to the increase of CO2 concentration in the atmosphere. | CHEN Yi WU Chun-yan SHUI Jian-guo WANG Jia-yu | 2006 | Agricultural Sciences in China2006,5,6: | 7 |
| 6 | Predictive value of K-ras and PIK3CA in non-small cell lung cancer patients treated with EGFR-TKIs: a systemic review and meta-analysis显示文摘Objective: A meta-analysis was performed to augment the insufficient data on the impact of mutative EGFR downstream phosphatidylinositol-3-kinase(PI3K) and mitogen-activated protein kinase(MAPK) pathways on the clinical efficiency of epidermal growth factor receptor tyrosine kinase inhibitor(EGFR-TKI) treatment of non-small cell lung cancer(NSCLC) patients.Methods: Network databases were explored in April, 2015. Papers that investigated the clinical outcomes of NSCLC patients treated with EGFR-TKIs according to the status of K-ras and/or PIK3 CA gene mutation were included. A quantitative meta-analysis was conducted using standard statistical methods. Odds ratios(ORs) for objective response rate(ORR) and hazard ratios(HRs) for progression-free survival(PFS) and overall survival(OS) were calculated.Results: Mutation in K-ras significantly predicted poor ORR [OR =0.22; 95% confidence interval(CI), 0.13-0.35], shorter PFS(HR =1.56; 95% CI, 1.27-1.92), and shorter OS(HR =1.59; 95% CI, 1.33-1.91) in NSCLC patients treated with EGFR-TKIs. Mutant PIK3 CA significantly predicted shorter OS(HR =1.83; 95% CI, 1.05-3.20), showed poor ORR(OR =0.70; 95% CI, 0.22-2.18), and shorter PFS(HR =1.79; 95% CI, 0.91-3.53) in NSCLC patients treated with EGFR-TKIs.Conclusion: K-ras mutation adversely affected the clinical response and survival of NSCLC patients treated with EGFRTKIs. PIK3 CA mutation showed similar trends. In addition to EGFR, adding K-ras and PIK3 CA as routine gene biomarkers in clinical genetic analysis is valuable to optimize the effectiveness of EGFR-TKI regimens and identify optimal patients who will benefit from EGFR-TKI treatment. | Jie-Ying Chen Ya-Nan Cheng Lei Han Feng Wei Wen-Wen Yu Xin-Wei Zhang Shui Cao Jin-Pu Yu | 2015 | Cancer Biology & Medicine2015,12,2: | 6 |
| 7 | Extraction of hydrogen chloride by a coupled reaction-solvent extraction process显示文摘A coupled 反应溶剂抽取过程被用来把 HCl 从模仿的蒸馏器浪费移开。各种各样的提炼之物和 diluents 的抽取表演被比较,在各种各样的 diluents 的 N235 (第三级的胺的混合物) 的明显的盐基度是坚定的。最好的结果作为提炼之物用 N235 和 isoamyl 酒精被获得并且稀释分别地。从联合抽取的 HCl 的收益与这个抽取系统是 75% 。为在两个的 HCl 的移动的机制直接、联合的抽取被调查。为联合抽取, R 3 NHCl 离子对建筑群涉及 HCl 移动。为直接抽取,机制在 HCl 的高集中包含了氢契约的形成。 | Yunzhao Li Xingfu Song Guilan Chen Shuying Sun Yanxia Xu Jianguo Yu | 2015 | Frontiers of Chemical Science and Engineering2015,9,4: | 6 |
| 8 | Nanosheet-structured K–Co–MoS_2 catalyst for the higher alcohol synthesis from syngas: Synthesis and activation显示文摘The nanosheets structured K–Co–MoS_2 catalyst was prepared through a one-step hydrothermal synthesis combined with the wetness impregnation. The fresh catalyst has a high dispersion of Co–Mo–S active phase and no Co_9S_8 is found. The pure H_2 activated catalyst shows a higher intrinsic activity, especially the C_(2+) OH selectivity for the higher alcohol synthesis compared to the one activated by 5% H_2/N_2 atmosphere. The reason is attributed to that the pure H_2 activation more effectively suppresses the formation of Co_9S_8 and stabilizes the Co–Mo–S active phase during the reaction due to the formation of SH species. | Huan Li Wei Zhang Yinyin Wang Meiling Shui Song Sun Jun Bao Chen Gao | 2019 | Journal of Energy Chemistry2019,28,3: | 5 |
| 9 | Interactions and Biological Activity of Rare Earth Perchlorate Complexes with Alanine and Imidazole显示文摘The interactions of nine rare earth perchlorate complexes with alanine and imidazole were studied in methanol. The general formulae of these compounds are RE(Ala) 2Im(ClO 4) 3· n H 2O(RE=Ce, Pr, Nd, Sm, Eu, Gd, Tb, Yb) and La(Ala) 3Im(ClO 4) 3·H 2O, respectively. The composition and structure of the prepared compounds were determined by the chemical analysis, elemental analysis, IR spectroscopy, UV, FS spectroscopy, X ray powder diffraction, 1H NMR and solubility. The thermal decomposition processes of these complexes were studied on the basis of TG DTG. The preliminary bioassay shows that the compounds have a remarkable bacteriostasis effect on nine varieties of microbe. | HE Shui yang, CHEN Jun li, ZHANG Wei ping, LIU Xiang rong, SONG Di sheng ( Chemistry Department, North west University, Xi′an 710069, China) | 2001 | Journal of Rare Earths2001,19,1: | 5 |
| 10 | Microwave-induced Apoptosis and Cytotoxicity of NK Cells through ERK1/2 Signaling显示文摘Objective To investigate microwave-induced morphological and functional injury of natural killer(NK) cells and uncover their mechanisms. Methods NK-92 cells were exposed to 10, 30, and 50 m W/cm^2 microwaves for 5 min. Ultrastructural changes, cellular apoptosis and cell cycle regulation were detected at 1 h and 24 h after exposure. Cytotoxic activity was assayed at 1 h after exposure, while perforin and NKG2 D expression were detected at 1 h, 6 h, and 12 h after exposure. To clarify the mechanisms, phosphorylated ERK(p-ERK) was detected at 1 h after exposure. Moreover, microwave-induced cellular apoptosis and cell cycle regulation were analyzed after blockade of ERK signaling by using U0126. Results Microwave-induced morphological and ultrastructural injury, dose-dependent apoptosis(P < 0.001) and cell cycle arrest(P < 0.001) were detected at 1 h after microwave exposure. Moreover, significant apoptosis was still detected at 24 h after 50 m W/cm^2 microwave exposure(P < 0.01). In the 30 m W/cm^2 microwave exposure model, microwaves impaired the cytotoxic activity of NK-92 cells at 1 h and down regulated perforin protein both at 1 h and 6 h after exposure(P < 0.05). Furthermore, p-ERK was down regulated at 1 h after exposure(P < 0.05), while ERK blockade significantly promoted microwave-induced apoptosis(P < 0.05) and downregulation of perforin(P < 0.01). Conclusion Microwave dose-dependently induced morphological and functional injury in NK-92 cells, possibly through ERK-mediated regulation of apoptosis and perforin expression. | ZHAO Li LI Jing HAO Yan Hui GAO Ya Bing WANG Shui Ming ZHANG Jing DONG Ji ZHOU Hong Mei LIU Shu Chen PENG Rui Yun | 2017 | Biomedical and Environmental Sciences2017,30,5: | 5 |
| 11 | Synergy between metallic components of MoNi alloy for catalyzing highly efficient hydrogen storage of MgH2显示文摘Catalysts play a critical role in improving the hydrogen storage kinetics in Mg/MgH2 system.Exploring highly efficient catalysts and catalyst design principles are hot topics but challenging.The catalytic activity of metallic elements on dehydrogenation kinetics generally follows a sequence of Ti>Nb>Ni>V>Co>Mo.Herein,we report a highly efficient alloy catalyst composed of low-active elements of Mo and Ni(i.e.MoNi alloy)for MgH2 particles.MoNi alloy nanoparticles show excellent catalytic effect,even outperforming most advanced Ti-based catalysts.The synergy between Mo and Ni elements can promote the break of Mg-H bonds and the dissociation of hydrogen molecules,thus significantly improves the kinetics of Mg/MgH2 system.The MoNi-catalyzed Mg/MgH2 system can absorb and release 6.7 wt.%hydrogen within 60 s and 10 min at 300℃,respectively,and exhibits excellent cycling stability and low-temperature hydrogen storage performance.This study provides a strategy for designing efficient catalysts for hydrogen storage materials using the synergy of metal elements. | Meng Chen Yanhui Pu Zhenyang Li Gang Huang Xiaofang Liu Yao Lu Wukui Tang Li Xu Shuangyu Liu Ronghai Yu Jianglan Shui | 2020 | Nano Research2020,13,8: | 5 |
| 12 | Fast-Suppressor Screening for New Components in Protein Trafficking,Organelle Biogenesis and Silencing Pathway in Arabidopsis thaliana Using DEX-Inducible FREE1-RNAi Plants显示文摘Membrane trafficking is essential for plant growth and responses to external signals.The plant unique FYVE domain-containing protein FREE1 is a component of the ESCRT complex(endosomal sorting complex required for transport).FREE1 plays multiple roles in regulating protein trafficking and organelle biogenesis including the formation of intraluminal vesicles of multivesicular body(MVB),vacuolar protein transport and vacuole biogenesis,and autophagic degradation.FREE1 knockout plants show defective MVB formation,abnormal vacuolar transport,fragmented vacuoles,accumulated autophagosomes,and seedling lethality.To further uncover the underlying mechanisms of FREE1 function in plants,we performed a forward genetic screen for mutants that suppressed the seedling lethal phenotype of FREE1-RNAi transgenic plants.The obtained mutants are termed as suppressors of free1(sof).To date,229 putative sof mutants have been identified.Barely detecting of FREE1 protein with M3plants further identified 84 FREE1-related suppressors.Also145 mutants showing no reduction of FREE1 protein were termed as RNAi-related mutants.Through next-generation sequencing(NGS)of bulked DNA from F2mapping population of two RNAi-related sof mutants,FREE1-RNAi T-DNA inserted on chromosome 1 was identified and the causal mutation of putative sof mutant is being identified similarly.These FREE1-and RNAi-related sof mutants will be useful tools and resources for illustrating the underlying mechanisms of FREE1 function in intracellular trafficking and organelle biogenesis,as well as for uncovering the new components involved in the regulation of silencing pathways in plants. | Qiong Zhao Caiji Gao PoShing Lee Lin Liu Shaofang Li Tangjin Hu Jinbo Shen Shuying Pan Hao Ye Yunru Chen Wenhan Cao Yong Cui Peng Zeng Sheng Yu Yangbin Gao Liang Chen Beixin Mo Xin Liu Shi Xiao Yunde Zhao Silin Zhong Xuemei Chen Liwen Jiang | 2015 | Journal of Genetics and Genomics2015,42,6: | 4 |
| 13 | Performance improvement of lithium-ion battery by pulse current显示文摘Periodically changed current is called pulse current.It has been found that using the pulse current to charge/discharge lithium-ion batteries can improve the safety and cycle stability of the battery.In this short review,the mechanisms of pulse current improving the performance of lithium-ion batteries are summarized from four aspects:activation,warming up,fast charging and inhibition of lithium dendrites.Related content may help us use the pulse current to improve the performance of lithium-ion batteries and further optimize pulse current technology. | Shaoqing Zhu Chen Hu Ye Xu Yi Jin Jianglan Shui | 2020 | Journal of Energy Chemistry2020,29,7: | 4 |
| 14 | Mea6 controls VLDL transport through the coordinated regulation of COPil assembly显示文摘 | Yaqing Wang Liang Liu Hongsheng Zhang Junwan Fan FengZhang Mei Yu Lei Shi Lin Yang Sin Man Lam Huimin Wang Xiaowei Chen Yingchun Wang Fei Gao Guanghou Shui Zhiheng Xu | 2016 | Cell Research2016,26,7: | 4 |
| 15 | The role of MAPK and FAS death receptor pathways in testicular germ cell apoptosis induced by lead显示文摘现在的学习的目的是调查在阴囊的细菌房间的导致铅的 apoptosis 涉及 MAPK 的信号小径和船边交货的死亡信号受体小径的基因表示。首先,房间生存能力被 MTT 试金决定。第二,使用单个房间胶化电气泳动测试(彗星试金) 和染色技术, apoptotic 率和阴囊的细菌房间的房间 apoptosis 本地化的 TUNEL 在分别地与 0.15% , 0.3% ,和 0.6% 铅一起对待的老鼠被测量。第三, K 地岬, c-fos,船边交货,和活跃 caspase-3 蛋白质的 immunolocalization 被 immunohistochemistry 决定。最后,在 K 地岬, c-fos,船边交货,和活跃 caspase-3 的翻译层次的变化被西方的污点分析进一步检测。我们的结果证明铅能显著地以一种剂量依赖者方式导致阴囊的细菌房间 apoptosis (P < 0.01 ) 。机制是仔细与在 apoptotic 细菌房间的 K 地岬, c-fos,船边交货,和活跃 caspase-3 的增加的表情有关。在结论, K-ras/c-fos 和 Fas/caspase-3 死亡发信号受体小径在老鼠涉及阴囊的细菌房间的导致铅的 apoptosis。 | Shuying Dong Duoping Liang Na An Li Jia Yujuan Shan Chao Chen Kuo Sun Fei Niu Huiyan Li Songbin Fu | 2009 | Acta Biochimica et Biophysica Sinica2009,41,9: | 4 |
| 16 | An efficient route for synthesis of 2-alkylamino benzo[b]thieno[3,2-d]pyrimidin-4(3H)-one显示文摘carbodiimide 2,从 iminophosphorane 的 aza-Wittig 反应获得了 1 与烷基 isocyanates,反应了与主要对氨基给 2-alkylamino benzo [b ] thieno [3,2-d ] pyrimidin-4 (3H ) 4 和 5。标题混合物的形成机制被调查了。 | Min Hui Cao Sheng Zhen Xu Chang Shui Chen | 2011 | Chinese Chemical Letters2011,22,4: | 4 |
| 17 | Effects of correlative factors on the interdendritic melt flow brought by the bulge in continuous casting slabs显示文摘The effects of various factors on the flow speed of interdendritic melt were analyzed in detail in the process of continuous casting slabs. When the solid-liquid interface bends periodically, the expression of solute distribution in the columnar crystal zone was deduced, and the quantitative calculation was also made. The results show that the bulge and the interdendritic spacing are responsible for the flow speed of interdendritic melt. At the initial stage of solidification the bulge operates, and at the final stage the interdendritic spacing operates. The experimental results of macrosegregation in the slabs validated the calculated results of the flow speed of interdendritic melt, which shows that the calculated results are basically consistent with the experimental ones. | Shuying Chen Guowei Chang Jianzhong Wang Chunjing Wu | 2008 | Journal of University of Science and Technology Beijing2008,15,4: | 3 |
| 18 | On the critical particle size of soil with clogging potential in shield tunneling显示文摘Shield tunneling is easily obstructed by clogging in clayey strata with small soil particles.However,soil clogging rarely occurs in strata with coarse-grained soils.Theoretically,a critical particle size of soils should exist,below which there is a high risk of soil clogging in shield tunneling.To determine the critical particle size,a series of laboratory tests was carried out with a large-scale rotary shear apparatus to measure the tangential adhesion strength of soils with different particle sizes and water contents.It was found that the tangential adhesion strength at the soilesteel interface gradually increased linearly with applied normal pressure.When the particle size of the soil specimen was less than 0.15 mm,the interfacial adhesion force first increased and then decreased as the water content gradually increased;otherwise,the soil specimens did not manifest any interfacial adhesion force.The amount of soil mass adhering to the steel disc was positively correlated with the interfacial adhesion force,thus the interfacial adhesion force was adopted to characterize the soil clogging risk in shield tunneling.The critical particle size of soils causing clogging was determined to be 0.15 mm.Finally,the generation mechanism of interfacial adhesion force was explored for soils with different particle sizes to explain the critical particle size of soil with clogging risk in shield tunneling. | Shuying Wang Zihao Zhou Pengfei Liu Zhao Yang Qiujing Pan Weizhong Chen | 2023 | Journal of Rock Mechanics and Geotechnical Engineering2023,15,2: | 3 |
| 19 | Peginterferon Alfa-2a Plus Ribavirin for the Treatment of Dual Chronic Infection With Hepatitis B and C Viruses显示文摘 | Chun–Jen Liu Wan–Long Chuang Chuan–Mo Lee Ming–Lung Yu Sheng–Nan Lu Shun–Sheng Wu Li–Ying Liao Chi–Ling Chen Hsing–Tao Kuo You–Chen Chao Shui–Yi Tung Sien–Sing Yang Jia–Horng Kao Chen–Hua Liu Wei–Wen Su Chih–Lin Lin Yung–Ming Jeng Pei–Jer Chen Ding–Shinn | 2009 | Gastroenterology2009,,2: | 3 |
| 20 | Effect of Zn atom in Fe-N-C catalysts for electro-catalytic reactions: theoretical considerations显示文摘Due to the high specific surface area,abundant nitrogen and micropores,ZIF-8 is a commonly used precursor for preparing high performance Fe-N-C catalysts.However,the Zn element is inevitably remained in the prepared Fe-N-C catalyst.Whether the residual Zn element affects the catalytic activity and active site center of the Fe-N-C catalyst caused widespread curiosity,but has not been studied yet.Herein,we built several Fe,Zn,and N co-doped graphene models to investigate the effect of Zn atoms on the electrocatalytic performance of Fe-N-C catalysts by using density functional theory method.The calculation results show that all the calculated Fe-Zn-N_(x) structures are thermodynamically stable due to the negative formation energies and relative stabilities.The active sites around Fe and Zn atoms in the structure of Fe-Zn-N_(6)(III)show the lowest oxygen reduction reaction(ORR)and oxygen evolution reaction(OER)overpotentials of 0.38 and 0.43 V,respectively.The bridge site of Fe-Zn in Fe-Zn-N_(5) shows the lowest η^(HER) of−0.26 V.A few structures with a better activity than that of FeN_(4) or ZnN_(4) are attributed to the synergistic effects between Fe and Zn atoms.The calculated ORR reaction pathways on Fe-Zn-N6(III)show that H_(2)O is the final product and the ORR mechanism on the catalyst would be a four-electron process,and the existence of Zn element in the Fe-N-C catalysts plays a key role in reducing the ORR activation energy barrier.The results are helpful for the deep understand of high-performance Fe-N-C catalysts. | Yongcheng Li Riming Hu Zhibin Chen Xin Wan Jia-Xiang Shang Fu-He Wang Jianglan Shui | 2021 | Nano Research2021,14,3: | 3 |