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1Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19.Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral 2021Cellular & Molecular Immunology2021,18,9:2
2Production of laccase by Pynopoms sanguineus using 2,5-xylidine and ethanol 显示文摘VALERIANO V S SILVA A M F SANTIAGO M F 2009Brazilian J Mierobioi2009,40,4:1
3The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M 2010Science2010,330,6010:1
4Endurance performance:Genes or gene combinations?显示文摘GOMEZ-GALLEGO F SANTIAGO C GONZALEZ-FREIRE M 2009Int J Sports Med2009,30,:1
5GC factor 2 represses platelet-derived growth factor A-chain gene rranscription and is itself induced by arterial injury显示文摘KHACHIGIAN L M SANTIAGO F S RAFTY L A 0,,11:1
6Studies on the Pycnoporus sanguineus CCT-4518 laccase purified by hydrophobic interaction chromatography 显示文摘GARCIA T A SANTIAGO M F ULHOA C J 2007Appl Microbiol Biot2007,75,2:1
7Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS) 显示文摘Santiago F Goncalo M Vieira R 2010Contact Dermatitis2010,62,1:1
8Immunophenotyping of Acute Leukemias and Myelodysysplastic Syndromes显示文摘Orfao A Ortuno F de Santiago M 2004Cytometry A2004,58,1:1
9Determination of the natural stress state in a Brazilian rock mass by back analyzing excavation measurements:a case study显示文摘FRANCO J A M ARMELIN J L SANTIAGO J A F 2002International Journal of Rock Mechanics and Mining Sciences2002,39,8:1
10New DNA enzyme targeting Egr-1 mRNA inhibits vascular smooth muscle proliferation and regrowth after injury显示文摘Santiago F S Lowe H C Kavurma M M 1999Nat Med1999,5,11:1
11Vermicompost as a soil supplement to improve growth, yield and fruit quality of tomato (Lycopersicum esculentum ) 显示文摘Guti6rrez - Miceli F A Santiago - Borraz J S Molina J A M 2007Bioresource Technology2007,98,15:1
12Mutation analysis of GJB2 and GJB6 genes in Southeastern Bratilians with hereditary nonsyndromic deafness显示文摘Cordeiro-Silva Mde F Barbosa A Santiago M 0,,02:1
13An object-oriented classification method for mapping mangroves in Guinea, West Africa, using multipolarized ALOS PALSAR L-band data显示文摘Santiago F F D Kovacs J M Lafrance P 2013International Journal of Remote Sensing2013,34,2:1
14Synthesis and swelling behavior of poly(sodium acrylate)/sepiolite superabsorbent composites and nanocomposites显示文摘Santiago F Mucientes A E Osorio M 2006Polymer International2006,55,8:1
15A new classification of Cyperaceae (Poales) supported by phylogenomic data显示文摘Cyperaceae(sedges)are the third largest monocot family and are of considerable economic and ecological importance.Sedges represent an ideal model family to study evolutionary biology due to their species richness,global distribution,large discrepancies in lineage diversity,broad range of ecological preferences,and adaptations including multiple origins of C4 photosynthesis and holocentric chromosomes.Goetghebeur′s seminal work on Cyperaceae published in 1998 provided the most recent complete classification at tribal and generic level,based on a morphological study of Cyperaceae inflorescence,spikelet,flower,and embryo characters,plus anatomical and other information.Since then,several family-level molecular phylogenetic studies using Sanger sequence data have been published.Here,more than 20 years after the last comprehensive classification of the family,we present the first family-wide phylogenomic study of Cyperaceae based on targeted sequencing using the Angiosperms353 probe kit sampling 311 accessions.In addition,62 accessions available from GenBank were mined for overlapping reads and included in the phylogenomic analyses.Informed by this backbone phylogeny,a new classification for the family at the tribal,subtribal,and generic levels is proposed.The majority of previously recognized suprageneric groups are supported,and for the first time,we establish support for tribe Cryptangieae as a clade including the genus Koyamaea.We provide a taxonomic treatment including identification keys and diagnoses for the 2 subfamilies,24 tribes,and 10 subtribes,and basic information on the 95 genera.The classification includes five new subtribes in tribe Schoeneae:Anthelepidinae,Caustiinae,Gymnoschoeninae,Lepidospermatinae,and Oreobolinae.Isabel Larridon Alexandre R.Zuntini Étienne Léveillé-Bourret Russell L.Barrett Julian R.Starr AMuthama Muasya Tamara Villaverde Kenneth Bauters Grace E.Brewer Jeremy J.Bruhl Suzana M.Costa Tammy L.Elliott Niroshini Epitawalage Marcial Escudero Isabel Fairlie Paul Goetghebeur Andrew LHipp Pedro Jiménez-Mejías Izai ABSabino Kikuchi Modesto Luceño JoséIgnacio Márquez-Corro Santiago Martín-Bravo Olivier Maurin Lisa Pokorny Eric HRoalson Ilias Semmouri David A.Simpson Daniel Spalink WWayt Thomas Karen L.Wilson Martin Xanthos Félix Forest William J.Baker 2021Journal of Systematics and Evolution2021,59,4:1
16Recru- itment maneuver in experimental acutelung injury: the role of alveolar collapse and edema显示文摘Santiago V R Rzezinski A F Nardelli L M 2010Crit Care Med2010,38,11:1
17Creating a conunon grammar for European higher education governance 显示文摘MAGALHXES A VEIGA A RIBEIRO F M SOUSA S SANTIAGO R 2013Higher Education2013,65,1:1
18Modified ac- tivated carbons for catalytic wet air oxidation of phenol 显示文摘Santiago M Stuber F Fortuny A 2005Carbon2005,43,:1
19Reticulated hyaluronic acid implant in nonperforating trabecular surgery 显示文摘Sourdille P Santiago PY Villain F Yamamichi M Tahi H Pare JM 1999J Cataract Refract Surg1999,25,:1
20Use of oral calcium loading to characterize the hypercalciuria of young insulin-dependent diabetics显示文摘 WHITE N H SANTIAGO J V 1983J Clin Endoc Metab1983,57,1:1
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