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| 1 | The Cretaceous Songliao Basin:Volcanogenic Succession,Sedimentary Sequence and Tectonic Evolution,NE China显示文摘Songliao 盆(SB ) 是有盆的二种不同类型的迭加的盆充满。更低的被一座围住差错的火山描绘包括的遗传因子的继任设置暴烈,碎屑状的焦性没食子酸和 epiclastic 岩石。暴烈的岩石,从 110 妈标明日期到 130 妈,具有 geochemically 活跃的大陆人边缘类型。快,向北方, SB 块的移植发生在从他们的 paleomagnetic 信息推断的火山作用的主要事件期间。上面盆之一充满被非海洋的下垂风格统治 siliciclastics 和次要的碳酸盐的沉积顺序。盆中心向西变了从对在盆进化建议动态变化的 GGT 地震速度结构揭示的迟了的白垩纪早。因此,一个迭加的盆模型被建议。SB 的进化包含包括的三个时期(1 ) Alptian 和 pre-Aptian:制动火箭弧盆和安第斯山脉的范围系统与蒙古鄂霍次克海 collisional 带(MOCB ) 有关打字;(2 ) Albian 到 Companian:在与沿着欧亚的板的东方边缘的和平的板的倾斜的 subduction 有关的 transtension 下面的象下垂一样罢工滑倒盆;(3 ) 自从 Maastrichtian:在与在欧亚的板下面的和平的板的正常 subduction 有关的压缩下面的构造的反的盆,由掩冲断层描绘了,向西 depocenter 的移植并且盆边缘的东方高举。 | WANG Pujun XIE Xiao'an Mattem FRANK REN Yanguang ZHU Defeng SUN Xiaomeng | 2007 | Acta Geologica Sinica(English Edition)2007，81，6： | 38 |
| 2 | SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2显示文摘 | Huize Pan Di Guan Xiaomeng Liu Jingyi Li Lixia Wang Jun Wu Junzhi Zhou Weizhou Zhang Ruotong Ren Weiqi Zhang Ying Li Jiping Yang Ying Hao Tingting Yuan Guohong Yuan Hu Wang Zhenyu Ju Zhiyong Mao Jian Li Jing Qu FuchouTang Guang-Hui Liu | 2016 | Cell Research2016，26，2： | 32 |
| 3 | Interactive effects of wind speed,vegetation coverage and soil moisture in controlling wind erosion in a temperate desert steppe,Inner Mongolia of China显示文摘The rapid desertification of grasslands in Inner Mongolia of China poses a significant ecological threaten to northern China. The combined effects of anthropogenic disturbances(e.g., overgrazing) and biophysical processes(e.g., soil erosion) have led to vegetation degradation and the consequent acceleration of regional desertification. Thus, mitigating the accelerated wind erosion, a cause and effect of grassland desertification, is critical for the sustainable management of grasslands. Here, a combination of mobile wind tunnel experiments and wind erosion model was used to explore the effects of different levels of vegetation coverage, soil moisture and wind speed on wind erosion at different positions of a slope inside an enclosed desert steppe in the Xilamuren grassland of Inner Mongolia. The results indicated a significant spatial difference in wind erosion intensities depending on the vegetation coverage, with a strong decreasing trend from the top to the base of the slope. Increasing vegetation coverage resulted in a rapid decrease in wind erosion as explained by a power function correlation. Vegetation coverage was found to be a dominant control on wind erosion by increasing the surface roughness and by lowering the threshold wind velocity for erosion. The critical vegetation coverage required for effectively controlling wind erosion was found to be higher than 60%. Further, the wind erosion rates were negatively correlated with surface soil moisture and the mass flux in aeolian sand transport increased with increasing wind speed. We developed a mathematical model of wind erosion based on the results of an orthogonal array design. The results from the model simulation indicated that the standardized regression coefficients of the main effects of the three factors(vegetation coverage, soil moisture and wind speed) on the mass flux in aeolian sand transport were in the following order: wind speed>vegetation coverage>soil moisture. These three factors had different levels of interactive effects on the mass flux in aeolian sand transport. Our results will improve the understanding of the interactive effects of wind speed, vegetation coverage and soil moisture in controlling wind erosion in desert steppes, and will be helpful for the design of desertification control programs in future. | MENG Zhongju DANG Xiaohong GAO Yong REN Xiaomeng DING Yanlong WANG Meng | 2018 | Journal of Arid Land2018，10，4： | 19 |
| 4 | Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding显示文摘 | Jiping Yang Jingyi Li Keiichiro Suzuki Xiaomeng Liu Jun Wu Weiqi Zhang Ruotong Ren Weizhou Zhang Piu Chan Juan Carlos Izpisua Belmonte Jing Qu Fuchou Tang Guang-Hui Liu | 2017 | Cell Research2017，27，9： | 12 |
| 5 | Retransmission or redundancy:Transmission reliability study in wireless sensor networks显示文摘As an application-driven network,wireless sensor network generally requires data reliability to maintain detection and response capabilities.Although two approaches,namely,retransmission and redundancy,have been proposed to enhance data reliability,the theoretical work is required to evaluate their impact on transmission reliability and energy efficiency.In this paper,we offer a comprehensive theoretical study on packet arrival probability and average energy consumption for both approaches.Our analysis and simulations indicate that when loss probabilities remain low or moderate,erasure coding,a typical redundancy-based scheme,is more energy efficient than retransmission.We also demonstrate that the resistance capability of erasure coding against packet loss weakens as the hop number increases,which motivates us to propose two improved mechanism based on the idea of the loss detection and the loss recovery.Finally,the simulation results carried out using TOSSIM verify the performance of different mechanisms both in the chain topology and the tree topology. | WEN Hao LIN Chuang REN FengYuan ZHOU Jia YUE Yao HUANG XiaoMeng | 2012 | Science China(Information Sciences)2012，55，4： | 7 |
| 6 | A novel intronic circular RNA,circGNG7,inhibits head and neck squamous cell carcinoma progression by blocking the phosphorylation of heat shock protein 27 at Ser78 and Ser82显示文摘Background:There is increasing evidence that circular RNAs(circRNAs)play a significant role in pathological processes including tumorigenesis.In contrast to exonic circRNAs,which are the most frequently reported circRNAs in cancer so far,the studies of intronic circRNAs have been greatly lagged behind.Here,we aimed to investigate the regulatory role of intronic circRNAs in head and neck squamous cell carcinoma(HNSCC).Methods:We conducted whole-transcriptome sequencing with four pairs of primary tumor tissues and adjacent normal tissues from HNSCC patients.Then,we characterized circGNG7 expression in HNSCC tissues and cell lines and explored its association with the prognosis of HNSCC patients.We also identified interactions between circGNG7 and functional proteins,which alter downstream signaling that regulate HNSCC progression.Results:In this study,we identified a new intronic circRNA,circGNG7,and validated its functional roles in HNSCC progression.CircGNG7 was predominately localized to the cytoplasm,and its expression was downregulated in both HNSCC tissues andCAL27,CAL33,SCC4,SCC9,HN6,and HN30 cells.Low expression of circGNG7 was significantly correlated with poor prognosis in HNSCC patients.Consistent with this finding,overexpression of circGNG7 strongly inhibited tumor cell proliferation,colony formation,in vitro migration,and in vivo tumor growth.Mechanistically,the expression of circGNG7 in HNSCC cells was regulated by the transcription factor SMAD family member 4(SMAD4).Importantly,we discovered that circGNG7 could bind to serine residues 78 and 82 of the functional heat shock protein 27(HSP27),occupying its phosphorylation sites and hindering its phosphorylation,which reduced HSP27-JNK/P38 mitogen-activated protein kinase(MAPK)oncogenic signaling.Downregulation of circGNG7 expression in HNSCC increased HSP27-JNK/P38 MAPK signaling and promoted tumor progression.Conclusions:Our results revealed that a new intronic circRNA,circGNG7,functions as a strong tumor suppressor and that circGNG7/HSP27-JNK/P38 MAPK signaling is a novel mechanism by which HNSCC progression can be controlled. | Houyu Ju Zhenrong Hu Dongliang Wei Jinyun Huang Xinyi Zhang Mengyu Rui Zhi Li Xiaomeng Zhang Jingzhou Hu Wei Guo Guoxin Ren | 2021 | Cancer Communications2021，41，11： | 4 |
| 7 | Can the dual-functional capability of CIK cells be used to improve antitumor effects?显示文摘 | Xiaomeng Wang Wenwen Yu Hui Li Jinpu Yu Xinwei Zhang Xiubao Ren Shui Cao | 2014 | Cellular Immunology2014，，1： | 2 |
| 8 | Postnatal state transition of cardiomyocyte as a primary step in heart maturation显示文摘Postnatal heart maturation Is the basis of normal cardiac function and provides critical insights into heart repair and regenerative medicine.While static snapshots of the maturing heart have provided much Insight into its molecular signatures,few key events during postnatal cardiomyocyte maturation have been uncovered.Here,we report that cardiomyocytes(CMs)experience epige-netic and transcriptional decline of cardiac gene expression immediately after birth,leading to a transi-tion state of CMs at postnatal day 7(P7)that was essential for CM subtype specification during heart maturation.Large-scale single-cell analysis and genetic lineage tracing confirm the presence of transition state CMs at P7 bridging immature state and mature states.Silencing of key transcription factor JUN In P1-hearts significantly repressed CM transition,resulting in per-turbed CM subtype proportions and reduced cardiac function in mature hearts.In addition,transplantation of P7-CMs into infarcted hearts exhibited cardiac repair potential superior to P1-CMs.Collectively,our data uncover CM state transition as a key event in postnatal heart maturation,which not only provides insights into molecular foundations of heart maturation,but also opens an avenue for manipulation of cardiomyocyte fate in disease and regenerative medicine. | Zheng Li Fang Yao Peng Yu Dandan Li Mingzhi Zhang Lin Mao Xiaomeng Shen Zongna Ren Li Wang Bingying Zhou | 2022 | Protein & Cell2022，13，11： | 2 |
| 9 | A novel high speed transport protocol based on explicit virtual load feedback显示文摘 | Huang Xiaomeng Lin Chuang Ren Fengyuan | 2007 | Computer Networks2007，51，7： | 1 |
| 10 | Brasenia-inspired hydrogel with sustained and sequential release of BMP and WNT activators for improved bone regeneration显示文摘Although bone morphogenetic protein(BMP) and WNT signaling play pivotal roles in bone development,homeostasis, and regeneration, the applications of proteins to stimulate corresponding signaling pathways showed limited outcomes in the repair and regeneration of bone defects that might be attributed to the reciprocal interventions of these pathways. In order to satisfy the combinational and sequential activation of BMP and WNT pathways, inspired by the heterogeneous hydrogel-liked structures of Brasenia, heterogeneous alginate/chitosan hydrogels were fabricated and spatially loaded with FK506 and BIO to achieve sustained and sequential release of the activators. Alkaline phosphatase staining, alizarin red staining and q RT-PCR results suggested that FK506 and BIO enhanced osteoblastic differentiation in vitro when used separately. Besides, by mixing and matching the activators and the hydrogel layers, a superior releasing mode that a combination of early FK506 release and following BIO release was identified via both in vitro and in vivo explorations for most efficient bone regeneration. These results suggested that drug-loaded heterogeneous hydrogels possess great potentials in treating bone loss defects for future clinical practice. | Xinqing Hao Xuewei Zhang Yue Hu Chunxia Ren Cangwei Liu Lu Wang Yijun Zhou Shuangshuang Wang Huanyu Luo Guangxing Yan Xiao Wang Xiaomeng Wang Feilong Ren Ce Shi, Wenlong Song Hongchen Sun | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 11 | Palladium Nanoparticles Supported on a Porous Organic Polymer: An Efficient Catalyst for Suzuki-Miyaura and So- nogashira Coupling Reactions显示文摘有高热的稳定性和大表面区域的新多孔的器官的聚合物(流行音乐) 在 Pd/POP 催化剂的准备被综合了并且适用。Pd/POP 被 XRD, TGA, SEM 和 TEM 描绘。催化剂与 650 m 2/g 的一个大表面区域在流行音乐上由 0.9-4 nm 尺寸的高度驱散的钯 nanoparticles 组成。它为 Suzuki-Miyaura 和 Sonogashira 反应介绍高催化的活动。没有活动的重要损失,催化剂在三~五次是可重用的。 | Xiaomeng Ren Shengnan Kong Qiding Shu Mouhai Shu | 2016 | Chinese Journal of Chemistry2016，34，4： | 0 |
| 12 | Gradient carbonyl-iron/carbon-fiber reinforced composite metamaterial for ultra-broadband electromagnetic wave absorption by multi-scale integrated design显示文摘The demand of high-end electromagnetic wave absorbing materials puts forward higher requirements on comprehensive performances of small thickness,lightweight,broadband,and strong absorption.Herein,a novel multi-layer stepped metamaterial absorber with gradient electromagnetic properties is proposed.The complex permittivity and permeability of each layer are tailored via the proportion of carbonyliron and carbon-fiber dispersing into the epoxy resin.The proposed metamaterial is further optimized via adjusting the electromagnetic parameters and geometric sizes of each layer.Comparing with the four-layer composite with gradient electromagnetic properties which could only realize reflection loss(RL)of less than−6 dB in 2.0-40 GHz,the optimized stepped metamaterial with the same thickness and electromagnetic properties realizes less than−10 dB in the relevant frequency range.Additionally,the RL of less than−15 dB is achieved in the frequency range of 11.2-21.4 GHz and 28.5-40 GHz.The multiple electromagnetic wave absorption mechanism is discussed based on the experimental and simulation results,which is believed to be attributed to the synergy effect induced by multi-scale structures of the metamaterial.Therefore,combining multi-layer structures and periodic stepped structures into a novel gradient absorbing metamaterial would give new insights into designing microwave absorption devices for broadband electromagnetic protections. | Qian Zhou Tiantian Shi Bei Xue Shengyue Gu Wei Ren Fang Ye Xiaomeng Fan Wenyan Duan Zihan Zhang Lifei Du | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，6： | 0 |
| 13 | A novel lightweight metamaterial with ultra broadband electromagnetic wave absorption induced by three-dimensional CNTs conductive-coated arrays显示文摘Lightweight metamaterials for broadband electromagnetic wave absorption have become a significant requirement for electromagnetic interference and stealth technologies.In this study,a novel lightweight metamaterial absorber with three-dimensional(3D)carbon nanotubes(CNTs)conductive-coated arrays is designed and fabricated through 3D printing and dipping process,which realized less than-10 dB reflection loss in the frequency range of 7.0–40 GHz.The effect of the sheet resistance of CNTs conductive coatings and geometric parameters of meta-structure on the frequency-dependent absorption properties is investigated,and the improved absorbing efficiency is discussed based on the synergy effect of multiscale structures of 3D conductive-coated arrays.Moreover,the volume of the proposed ultra broadband absorber is reduced by approximately 60.5%compared with that of the dense plate structure,indicating a significant lightening with efficient absorbing capacities.Additionally,the absorption bandwidth and intensity of the proposed absorber have insensitive changes with the variation of incident angle.Therefore,an ultra broadband electromagnetic absorption is designed and realized,indicating a promising lightweight ultra broadband electromagnetic absorbing candidate for lightweight metamaterial absorbers. | ZHOU Qian SHI TianTian XUE Bei GU ShengYue REN Wei YE Fang FAN XiaoMeng ZHANG YuXin QI ChenXi DU LiFei | 2023 | Science China(Technological Sciences)2023，66，3： | 0 |
| 14 | Rational design of ZnCdS/TpPa-1-COF heterostructure photocatalyst by strengthening the interface connection in solar hydrogen production reactions显示文摘ZnCdS quantum dots(QDs)are highly coveted in photocatalysis research for their exceptional visible-light responses and high light-absorption coefficients.However,their practical application is hindered by their tendency to aggregate,due to having high surface energies.To address this issue,herein,a heterostructure is synthesized by growing ZnCdS QDs with a size of approximately 5 nm onto the surface of a two-dimensional(2D)covalent organic framework(COF),TpPa-1-COF.This approach suppresses the aggregation of the QDs and improves their stability.The ZnCdS/TpPa-1-COF composite exhibited a peak hydrogen evolution rate of 6244.16μmol·g^(-1)·h^(-1),which was 2.89 and 4.18 times greater than that of ZnCdS and TpPa-1-COF,respectively.The zero-dimensional/two-dimensional(0D/2D)heterojunction formed by ZnCdS and TpPa-1-COF generates a strong interfacial force,which is attributed to the intimate contact between the interfaces.Tight connections accelerate charge separation,improve the utilisation of reduced electrons,and reduce the extent of agglomeration of the ZnCdS QDs,thereby resulting in high hydrogen production activity of the composites.Meanwhile,the photocatalytic mechanism is studied using Kelvin probe force microscopy and theoretical calculations.This study offers a novel approach for creating sulfide photocatalysts and is crucial for investigating the potential practical applications of the related photocatalysts. | Di Yang Zhi-Gang Li Xinghao Zhang Zenghuan Ren Weihan Lu Haining Liu Xiaomeng Guo Jijie Zhang Xian-He Bu | 2024 | Nano Research2024，17，3： | 0 |
| 15 | Multiple SiGe/Si layers epitaxy and SiGe selective etching for vertically stacked DRAM显示文摘Fifteen periods of Si/Si_(0.7)Ge_(0.3)multilayers(MLs)with various Si Ge thicknesses are grown on a 200 mm Si substrate using reduced pressure chemical vapor deposition(RPCVD).Several methods were utilized to characterize and analyze the ML structures.The high resolution transmission electron microscopy(HRTEM)results show that the ML structure with 20 nm Si_(0.7)Ge_(0.3)features the best crystal quality and no defects are observed.Stacked Si_(0.7)Ge_(0.3)ML structures etched by three different methods were carried out and compared,and the results show that they have different selectivities and morphologies.In this work,the fabrication process influences on Si/Si Ge MLs are studied and there are no significant effects on the Si layers,which are the channels in lateral gate all around field effect transistor(L-GAAFET)devices.For vertically-stacked dynamic random access memory(VS-DRAM),it is necessary to consider the dislocation caused by strain accumulation and stress release after the number of stacked layers exceeds the critical thickness.These results pave the way for the manufacture of high-performance multivertical-stacked Si nanowires,nanosheet L-GAAFETs,and DRAM devices. | Zhenzhen Kong Hongxiao Lin Hailing Wang Yanpeng Song Junjie Li Xiaomeng Liu Anyan Du Yuanhao Miao Yiwen Zhang Yuhui Ren Chen Li Jiahan Yu Jinbiao Liu Jingxiong Liu Qinzhu Zhang Jianfeng Gao Huihui Li Xiangsheng Wang Junfeng Li Henry HRadamson Chao Zhao Tianchun Ye Guilei Wang | 2023 | Journal of Semiconductors2023，44，12： | 0 |
| 16 | An efficient transient gene expression system for protein subcellular localization assay and genome editing in citrus protoplasts显示文摘Protoplast has been widely used in biotechnologies to circumvent the breeding obstacles in citrus, including long juvenility, polyembryony, and male/female sterility. The protoplast-based transient gene expression system is a powerful tool for gene functional characterization and CRISPR/Cas9 genome editing in higher plants, but it has not been widely used in citrus. In this study, the polyethylene glycol(PEG)-mediated method was optimized for citrus callus protoplast transfection, with an improved transfection efficiency of 68.4%. Consequently, the efficiency of protein subcellular localization assay was increased to 65.8%, through transient expression of the target gene in protoplasts that stably express the fluorescent organelle marker protein. The gene editing frequencies in citrus callus protoplasts reached 14.2% after transient expression of CRISPR/Cas9 constructs. We demonstrated that the intronic polycistronic tRNAgRNA(inPTG) genome editing construct was functional in both the protoplast transient expression system and epicotyl stable transformation system in citrus. With this optimized protoplast transient expression system, we improved the efficiency of protein subcellular localization assay and developed the genome editing system in callus protoplasts, which provides an approach for prompt test of CRISPR vectors. | Wenhui Yang Jiaqin Ren Wanrong Liu Dan Liu Kaidong Xie Fei Zhang Pengwei Wang Wenwu Guo Xiaomeng Wu | 2023 | Horticultural Plant Journal2023，9，3： | 0 |
| 17 | On-orbit geometric calibration of satellite laser altimeters using infrared detectors and corner-cube retroreflectors显示文摘After being launched into orbit,the geometric calibration of a satellite laser altimeter will reduce errors in laser pointing and ranging caused by satellite vibrations during launch,environmental changes,and thermal effects during long-term operation,which guarantees the accuracy of measurement data.In this study,a satellite laser geometric calibration method combining infrared detectors and corner-cube retroreflectors(CCRs)is proposed.First,a CCR-based laser ranging error calibration method was established,and then a laser pointing error calibration model was derived based on a single infrared detector array.Taking GaoFen-7(GF-7)satellite laser beam 2 as the experimental object,laser geometric calibration was realized using an infrared detector and CCR-measured data.Then,the accuracy of the proposed method was compared with that of other calibration methods,the CMLID and the CMSPR.The results show that the accuracy of the proposed calibration method is equivalent to that of the CMLID and higher than that of the CMSPR.Among them,the accuracy of the laser pointing after calibration using the proposed method is better than 0.8 arcsec,and the elevation accuracy of the laser on flat,sloping,and mountainous terrains is better than 0.11 m,0.30 m,and 1.80 m,respectively. | Junfeng Xie Ren Liu Xiaomeng Yanga Fan Mo Fangxu Zhang Lirong Liu | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 18 | Single-cell epigenome analysis reveals age-associated decay of heterochromatin domains in excitatory neurons in the mouse brain显示文摘Loss of heterochromatin has been implicated as a cause of pre-mature aging and age-associated decline in organ functions in mammals;however,the specific cell types and gene loci affected by this type of epigenetic change have remained unclear.To address this knowledge gap,we probed chromatin accessibility at single-cell resolution in the brains,hearts,skeletal muscles,and bone marrows from young,middle-aged,and old mice,and assessed age-associated changes at 353,126 candidate cis-regulatory elements(cCREs)across 32 major cell types.Unexpectedly,we detected increased chromatin accessibility within specific heterochromatin domains in old mouse excitatory neurons.The gain of chromatin accessibility at these genomic loci was accompanied by the cell-type-specific loss of heterochromatin and activation of LINE1 elements.Immunostaining further confirmed the loss of the heterochromatin mark H3K9me3 in the excitatory neurons but not in inhibitory neurons or glial cells.Our results reveal the cell-type-specific changes in chromatin landscapes in old mice and shed light on the scope of heterochromatin loss in mammalian aging. | Yanxiao Zhang Maria Luisa Amaral Chenxu Zhu Steven Francis Grieco Xiaomeng Hou Lin Lin Justin Buchanan Liqi Tong Sebastian Preissl Xiangmin Xu Bing Ren | 2022 | Cell Research2022，32，11： | 0 |
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