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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | 新型低密度脂蛋白胆固醇评估对全球血脂异常指南中次级靶标非高密度脂蛋白胆固醇和载脂蛋白B应用的影响显示文摘血脂异常指南通常推荐非高密度脂蛋白胆固醇(non-high-density lipoprotein-cholesterol,non-HDL-C)和载脂蛋白B(apolipoprotein B,apoB)作为主要靶点低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)的次要靶点。 | Sathiyakumar V Park J Quispe R Elshazly MB Michos ED Banach M Toth PP Whelton SP Blumenthal RS Jones SR Martin SS 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，4： | 4 |
| 3 | Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study显示文摘 | Hedy L Kindler Tatsuya Ioka Dirk J Richel Jaafar Bennouna Richard Létourneau Takuji Okusaka Akihiro Funakoshi Junji Furuse Young Suk Park Shinichi Ohkawa Gregory M Springett Harpreet S Wasan Peter C Trask Paul Bycott Alejandro D Ricart Sinil Kim Eric Van | 2011 | Lancet Oncology2011，，3： | 4 |
| 4 | Using a hash-based method with transaction trimming for mining association rules 显示文摘 | J S Park M S Chen P S Yu | 1997 | IEEE Transactions on Knowledge and Data Engineering1997，9，： | 2 |
| 5 | SiO2 aerogel film as a novel intermetal dielectric 显示文摘 | Jo M H Park H H Kim D J | 1997 | J Appl Phys1997，82，3： | 2 |
| 6 | Theoretical stress-strain model for confined concrete 显示文摘 | MANDER J B PRIESTLEY M J N PARK R | 1988 | Journal of Structural Engineering ASCE1988，114，8： | 2 |
| 7 | Electric load forecasting using an artificial neural network 显示文摘 | Park D C El-Sharkawi M A Marks R J | 1991 | IEEE Transactions on Power Systems1991，6，2： | 2 |
| 8 | Improved serpentine laminating micromixer with enhanced local advection显示文摘 | PARK J M KIM D S KANG T G | 2008 | Microfluidics and Nanofluidics2008，4，6： | 1 |
| 9 | The gas separation properties of carbon molecular sieve membranes derived from polyimides having carboxylic acid groups显示文摘 | Kim Y K Lee J M Park H B | 2004 | Journal of Membrane Science2004，235，： | 1 |
| 10 | Resistive switching behavior of Cr-doped SrZrO3 perovskite thin films for random access memory applications 显示文摘 | Yang M K Kim D Y Park J W | 2005 | J Korean Phy Soc2005，47，： | 1 |
| 11 | Effects of Panax ginseng extract on exercise- induced oxidative stress 显示文摘 | KIM S H PARK K S CHANG M J | 2005 | J Sports Med Phys Fitness2005，45，2： | 1 |
| 12 | Fluid-structure Interaction Analysis of 3-D Rectangular Tanks by a Variationally Coupled BEM-FEM and Comparison with Test Results显示文摘 | KOU H M KIM J A PARK Jang-ho | 1998 | Earthquake Engineering And Structural Dynamics1998，27，： | 1 |
| 13 | Why social networks are different from other types of networks 显示文摘 | NEWMAN M E PARK J | 2003 | Physical Review E2003，68，36： | 1 |
| 14 | Gas and water vapor barrier properties of edible films from protein and cellulosic materials 显示文摘 | Park H J Chinnan M S | 1995 | J Food Engr1995，25，： | 1 |
| 15 | Identification and characterization of Paragonimus westermani leucine aminopeptidase 显示文摘 | Song S M Park J H Kim J | 2008 | Parasitol Int2008，57，3： | 1 |
| 16 | A fast procedure for computing incremental growth distances显示文摘 | Hong S M Yeo J H Park H W | 2000 | Robotics2000，18，4： | 1 |
| 17 | Growth characteristics of carbon nanotubes via aluminum nanopore template on Si substrate using PECVD显示文摘 | Kim M J Choi J H Park J B | 2003 | ThinSolid Films2003，435，： | 1 |
| 18 | Toward secure distributed spectrum sensing in cognitive radio networks 显示文摘 | Chen R Park J M Hou Y T | 2008 | IEEE Commu- nication Magazine2008，4，： | 1 |
| 19 | 显示文摘 | Ryu S Park J H Jang H M | 2007 | Appl Phys Lett2007，91，14： | 1 |
| 20 | Using a hash-based method with transaction trirrrning formining association rules显示文摘 | Park J S Chen M S Yu P S | 1997 | Knowledge and Data Engineering IEEE Transactions1997，9，5： | 1 |
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