|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Promising strategies for the preven- tion of dementia显示文摘 | MIDDLETON L E YAFFE K | 2009 | Arch Neurol2009，66，10： | 1 |
| 3 | The structural ba- sis for 14-3-3 : phosphopeptide binding specificity 显示文摘 | Yaffe M B Rittinger K Volinia S | 1997 | Cell1997，91，7： | 1 |
| 4 | Serum lipoprotein levels, statin use and cognitive function in older women 显示文摘 | YAFFE K BARRETT-CONNOR E L N F | 2002 | Arch Neurol2002，59，3： | 1 |
| 5 | Sex hormones and cognitive function in older men显示文摘 | Yaffe K Lui LY Zmuda J | 2009 | J Am Geriatr Soc2009，50，： | 1 |
| 6 | Diabetes, glucose control, and 9- year cognitive decline among older adults without dementia 显示文摘 | Yaffe K Falvey C Hamilton N er al | 2012 | Arch Neurol2012，69，9： | 1 |
| 7 | A prospective study of physical activity and cognitive decline in elderly women:women who walk显示文摘 | Yaffe K Barnes D Nevitt M | 2001 | Arch Intern Med2001，161，14： | 1 |
| 8 | Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group 显示文摘 | Gregg EW Yaffe K Cauley JA | 2000 | Arch Intern Med2000，160，2： | 1 |
| 9 | A cognitive training program based on principles of brain plasticity:rosults from the Improvement in Memo- ry with Plasticity-based Adaptive Cognitive Training (IMPACT) study 显示文摘 | Smith GE Housen P Yaffe K | 2009 | J Am Geriatr Soc2009，57，4： | 1 |
| 10 | Promising strategies for the prevention of dementia显示文摘 | Middleton LE Yaffe K | | 0，，10： | 1 |
| 11 | Hippocampal volume is inversely related to PTSD duration 显示文摘 | Chao LL Yaffe K Samuelson K ct al | 2014 | Psychiatry Res2014，222，3： | 1 |
| 12 | Hypoglycemic episodesand risk of dementia in older patients with type 2 diabetes mellitus显示文摘 | Whitmer RA Karter AJ Yaffe K | 2009 | JAMA2009，301，15： | 1 |
| 13 | High occurrence of mood and anxiety disorders among older adults显示文摘 | Byers AL Yaffe K Covinsky kE | 2010 | Arch Gen Psychiatry2010，67，： | 1 |
| 14 | Estrogen use,ApoE,and cognitive decline evidence of gene-environment interaction 显示文摘 | Yaffe K Haum M Buers A | 2000 | Neurology2000，54，： | 1 |
| 15 | Structural de-terminants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms 显示文摘 | Gardino A K Smerdon S J Yaffe M B | 2006 | Seminars in Cancer Biology2006，16，3： | 1 |
| 16 | Physical activity over the life course and its association with cognitive performance and impairment in old age显示文摘 | Middleton LE Barnes DE Lui LY Yaffe K | | 0，，： | 1 |
| 17 | Dementia in the oldest old : a multi-factorial and growing public health issue显示文摘 | Gardner RC Valcour V Yaffe K | 2013 | Alzheimers Res Ther2013，5，4： | 1 |
| 18 | Estrogen use, ApoE, and cognitive decline : evidence of gene-environment interaction 显示文摘 | Yaffe K Haan M Buers A | 2000 | Neurology2000，54，： | 1 |
| 19 | Promising strategies for the prevention of dementia显示文摘 | Middleton LE Yaffe K | | 0，，10： | 1 |
| 20 | Changes in physical perform- anee in older women according to presence and treatment of diabetes mellitus 显示文摘 | Lee CG Schwartz AV Yaffe K | 2013 | J Am Geriatr Soc2013，61，11： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员