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| 1 | A Strigolactone Biosynthesis Gene Contributed to the Green Revolution in Rice显示文摘Plant architecture is a complex agronomic trait and a major factor of crop yield,which is affected by several important hormones.Strigolactones(SLs)are identified as a new class hormoneinhibiting branching in many plant species and have been shown to be involved in various developmental processes.Genetical and chemical modulation of the SL pathway is recognized as a promising approach to modify plant architecture.However,whether and how the genes involved in the SL pathway could be utilized in breeding still remain elusive.Here,we demonstrate that a partial loss-of-function allele of the SL biosynthesis gene,HIGH TILLERING AND DWARF 1/DWARF17(HTD1/D17),which encodes CAROTENOID CLEAVAGE DIOXYGENASE 7(CCD7),increases tiller number and improves grain yield in rice.We found that the HTD1 gene had been widely utilized and co-selected with Semidwarf 1(SD1),both contributing to the improvement of plant architecture in modern rice varieties since the Green Revolution in the 1960s.Understanding how phytohormone pathway genes regulate plant architecture and how they have been utilized and selected in breeding will lay the foundation for developing the rational approaches toward improving crop yield. | Yuexing Wang Lianguang Shang Hong Yu Longjun Zeng Jiang Hu Shen Ni Yuchun Rao Sanfeng Li Jinfang Chu Xiangbing Meng Lei Wang Ping Hu Jijun Yan Shujing Kang Minghao Qu Hai Lin Tao Wang Quan Wang Xingming Hu Hongqi Chen Bing Wang Zhenyu Gao Longbiao Guo Dali Zeng Xudong Zhu Guosheng Xiong Jiayang Li Qian Qian | 2020 | Molecular Plant2020，13，6： | 23 |
| 2 | Long-term thermal regimes of the Qinghai-Tibet Railway embankments in plateau permafrost regions显示文摘Ten years of ground temperature data(2003–2013) indicate that the long-term thermal regimes within embankments of the Qinghai-Tibet Railway(QTR) vary significantly with different embankment structures. Obvious asymmetries exist in the ground temperature fields within the traditional embankment(TE) and the crushed-rock basement embankment(CRBE). Measurements indicate that the TE and CRBE are not conducive to maintaining thermal stability. In contrast, the ground temperature fields of both the crushed-rock sloped embankment(CRSE) and the U-shaped crushed-rock embankment(UCRE) were symmetrical. However, the UCRE gave better thermal stability than the CRSE because slow warming of deep permafrost was observed under the CRSE. Therefore, the UCRE has the best long-term effect of decreasing ground temperature and improving the symmetry of the temperature field. More generally, it is concluded that construction using the cooling-roadbed principle meets the design requirements for long-term stability of the railway and for train transport speeds of 100 km h?1. However, temperature differences between the two shoulders, which exist in all embankments shoulders, may cause potential uneven settlement and might require maintenance. | NIU Fu un LIU MingHao CHENG GuoDong LIN ZhanJu LUO Jing YIN GuoAn | 2015 | Science China Earth Sciences2015，58，9： | 14 |
| 3 | Molecular mechanism of SCARB2-mediatec attachment and uncoating of EV71显示文摘 | Minghao Dang Xiangxi Wang Quan Wang Yaxin Wang Jianping Lin Yuna Sun Xuemei Li Liguo Zhang Zhiyong Lou Junzhi Wang Zihe Rao | 2014 | Protein & Cell2014，5，9： | 13 |
| 4 | Degradation of bisphenol-A using ultrasonic irradiation assisted by low-concentration hydrogen peroxide显示文摘This study investigated the degradation of bisphenol-A (BPA) by ultrasonic irradiation in the presence of different additives (H2O2,air bubbles and humic acid) under various operating conditions,i.e.,ultrasonic frequency,power intensity and power density.The results demonstrated that the BPA degradation followed pseudo first-order kinetics under different experimental conditions.The optimum power intensities were 0.9,1.8,and 3.0W/cm 2 at the frequencies of 400,670,and 800 kHz,respectively.At the fixed frequency (800 kHz),the degradation rate of BPA was shown proportional to the increase of power density applied.With this manner,the BPA sonolysis could be facilitated at H2O2 dosage being lower than 0.1 mmol/L;while BPA degradation was hindered at H2O2 concentration in excess of 1 mmol/L.Additionally,BPA removal was shown to be inhibited by the presence of aeration and humic acid during ultrasonic irradiation.The present study suggested that the degradation rate of BPA assisted by ultrasonic irradiation was influenced by a variety of factors,and high BPA removal rate could be achieved under appropriate conditions. | Kejia Zhang Naiyun Gao Yang Deng Tsair Fuh Lin Yan Ma Lei Li Minghao Sui | 2011 | Journal of Environmental Sciences2011，23，1： | 9 |
| 5 | Scalable microfabrication of three-dimensional porous interconnected graphene scaffolds with carbon spheres for high-performance all carbon-based micro-supercapacitors显示文摘As one of the most important micro energy storage devices(MESDs),graphene-based micro-supercapacitors(G-MSCs)possess the advantages of excellent flexibility,long cycle life,affordability and high reliability.In most cases,constructing three-dimensional(3D)graphene networks is widely utilized to promote the permeation of electrolyte and enhance the utilization of active materials.In this work,conventional freeze-drying process is utilized in the fabrication of G-MSCs to constitute 3D interconnected networks micro-electrodes,and further by regulating the composition of inks,carbon spheres(CSs)at different mass loadings are introduced into the graphene scaffolds to further increase the active sites of the micro-electrodes.The fabricated all carbon-based MSC with the optimal mass loading of CSs(0.406 mg cm^(-2))exhibits a high specific areal capacitance of 17.01mF cm^(-2)at the scan rate of 10mV s^(-1)and a capacitance retention of 93.14%after 10000 cycles at the scan rate of 500 mV s^(-1).The proposed microfabrication process is facile and fully compatible with modern microtechnologies and will be highly suitable for large-scale production and integration. | Yiming Chen Minghao Guo Liang He Wei Yang Lin Xu Jiashen Meng Xiaocong Tian Xinyu Ma Qiang Yu Kaichun Yang Xufeng Hong Liqiang Mai | 2019 | Journal of Materiomics2019，5，2： | 6 |
| 6 | Large-scale blow spinning of heat-resistant nanofibrous air filters显示文摘Particulate matter(PM)pollution has become a serious problem worldwide and various kinds of nanofibrous filters aiming to solve the problem have been developed.It is urgent to remove PM from high-temperature pollution sources,such as industrial emissions,coal furnaces,and automobile exhaust gases.However,filtration at pollution sources remains challenging because most existing air filters are not resistant to high temperature.Herein,heat-resistant polyimide(PI)nanofibrous air filters are fabricated via a simple and scalable solution blow-spinning method.These air filters show excellent thermal stability at high temperature up to 420℃.They exhibit a filtration efficiency as high as 99.73%at ambient temperature and over 97%at 300℃.In addition,a field test shows that the filters remove>97%of PM from the car exhaust fumes.Hence,the blow-spun PI nanofibrous membranes combined with the facile preparation strategy have great potential in high temperature air filtration fields and other similar applications such as water purification and protein separation. | Ziwei Li Jianan Song Yuanzheng Long Chao Jia Zhenglian Liu Lei Li Cheng Yang Junchen Liu Sen Lin Haiyang Wang Yibo Liu Minghao Fang Hui Wu | 2020 | Nano Research2020，13，3： | 6 |
| 7 | GOLM1 exacerbates CD8^(+)T cell suppression in hepatocellular carcinoma by promoting exosomal PD-L1 transport into tumor-associated macrophages显示文摘The immunosuppressive microenvironment plays an important role in tumor progression and immunotherapy responses.Golgi membrane protein 1(GOLM1)is correlated to hepatocellular carcinoma(HCC)progression and metastasis.However,little is known about the role of GOLM1 in regulating the immunosuppressive environment and its impact on immunotherapeutic efficacy in HCC.In this study,GOLM1 was positively correlated with infiltrating tumor-associated macrophages(TAMs)expressed high levels of programmed death-ligand 1(PD-L1)and CD8^(+)T cell suppression in HCC tissues.Both gain-and loss-of-function studies determined a close correlation between GOLM1 and immunosuppression.In the mechanism,GOLM1 promoted COP9 signalosome 5-mediated PD-L1 deubiquitination in HCC cells and increased the transport of PD-L1 into exosomes via suppression of Rab27b expression.Furthermore,co-culture with exosomes derived from HCC cells upregulated the expression of PD-L1 on macrophages.Zoledronic acid in combination with anti-PD-L1 therapy reduced PD-L1^(+)TAMs infiltration and alleviated CD8^(+)T cell suppression,resulting in tumor growth inhibition in the mouse HCC model.Together,our study unveils a mechanism by which GOLM1 induces CD8^(+)T cells suppression through promoting PD-L1 stabilization and transporting PD-L1 into TAMs with exosome dependent.Targeting PD-L1^(+)TAM could be a novel strategy to enhance the efficacy of anti-PD-L1 therapy in HCC. | Jinhong Chen Zhifei Lin Lu Liu Rui Zhang Yan Geng Minghao Fan Wenwei Zhu Ming Lu Lu Lu Huliang Jia Jubo Zhang Lun-Xiu Qin | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 5 |
| 8 | Fault line selection in cooperation with multi-mode grounding control for the floating nuclear power plant grid显示文摘The Floating nuclear power plant grid is composed of power generation,in-station power supply and external power delivery.To ensure the safety of the nuclear island,the in-station system adopts a special power supply mode,while the external power supply needs to be adapted to different types of external systems.Because of frequent single phase-ground faults and various fault forms,the fault line selection protection should be accurate,sensitive and adaptive.This paper presents a fault line selection method in cooperation with multi-mode grounding control.Based on the maximum united energy entropy ratio(MUEER),the optimal wavelet basis function and decomposition scale are adaptively chosen,while the fault line is selected by wavelet transform modulus maxima(WTMM).For high-impedance faults(HIFs),to enlarge the fault feature,the system grounding mode can be switched by the multi-mode grounding control.Based on the characteristic of HIFs,the fault line can be selected by comparing phase differences of zero-sequence current mutation and fault phase voltage mutation before and after the fault.Simulation results using MATLAB/Simulink show the effectiveness of the proposed method in solving the protection problems. | Yikai Wang Xin Yin Wen Xu Xianggen Yin Minghao Wen Lin Jiang | 2020 | Protection and Control of Modern Power Systems2020，5，1： | 3 |
| 9 | In-situ testing study on convection and temperature characteristics of a new crushed-rock slope embankment design in a permafrost region显示文摘For the purpose of enhancing air convection and controlling solar radiation, a new crushed-rock slope embankment design combined with a sun-shade measure is proposed. A newly designed embankment was constructed in the Tuotuohe section of the Qinghai-Tibet Railway and a field-testing experiment was carried out to determine its convection and temperature characteristics. The results show that distinct air convection occurred in the crushed-rock layer of the new embankment, especially in cold seasons, which was enhanced when it flowed upwards along the slope. This preliminarily indicated that the new design of the embankment slope was good for reinforcing air convection in the crushed-rock layer. The frequent fluctuations of the convection speed and the environmental wind speed were in good agreement, suggesting that the convection in the crushed rock primarily came from the ambient wind. It was also preliminarily determined that the new embankment had a better cooling effect and sun-shade effect for decreasing the temperature of the embankment slope compared with a traditional crushed-rock slope embankment, and the mean temperature difference between them was up to 1.7 °C. The mean annual temperature at the bottom boundary of the crushed-rock layer was obviously lower than that at the top boundary, and heat flux calculation showed that the shallow soil beneath the embankment slope was weakly releasing heat, all of which indicated that the new embankment slope design was beneficial to the thermal stability of the embankment. This study is helpful in providing some references for improved engineering design and maintenance of roadbeds in permafrost regions. | MingHao Liu FuJun Niu JianHong Fang ZhanJu Lin Jing Luo GuoAn Yin | 2014 | Research in Cold and Arid Regions2014，6，4： | 3 |
| 10 | Relationships between daily total fluoride intake and dental fluorosis and dental caries显示文摘Objective:To explore the relationships between the daily total intake of fluoride,dental fluorosis and dental caries. Methods: An epidemiological method was used to investigate the daily total intake of fluoride,dental fluorosis,and dental caries among 236 and 290 children aged 8-13 years in a severe endemic area and in a non-fluorosis control area,respectively. The children were divided into eight subgroups according to each child’s estimated daily total intake of fluoride. The prevalence of dental fluorosis and dental caries in each group was calculated. Results: As expected,elevated levels of fluoride intake were significantly associated with a higher prevalence of dental fluorosis and an increasing amount of more severe defect dental fluorosis. When the daily total F intake was 2.78 mg/child/day,the prevalence of dental fluorosis was nearly 100%,with the prevalence of defect dental fluorosis increasing with increasing fluoride intake. There was also a significant negative(inverse) dose-response relationship between the daily total intake of fluoride and the overall preva-lence of dental caries,the prevalence of which decreased when the daily total intake of fluoride increased up to 3.32 mg/child/day. However,at higher levels of daily total intake of fluoride the prevalence of dental caries increased,giving rise to a U-shaped dose-response relationship curve. Conclusion: It is important to monitor total fluoride exposure and protect children from excessive fluoride intake,especially during the years of tooth development. | Quanyong Xiang Minghao Zhou Ming Wu Xinya Zhou Li Lin Jiuning Huan Youxing Liang | 2009 | Journal of Nanjing Medical University2009，23，1： | 3 |
| 11 | Important population viability analysis parameters for giant pandas(Aliuropoda melanoleuca)显示文摘Population viability analysis(PVA) is a tool to evaluate the risk of extinction for endangered species and aid conservation decision-making.The quality of PVA output is dependent on parameters related to population dynamics and life-history;however,it has been difficult to collect this information for the giant panda(Aliuropoda melanoleuca),a rare and endangered mammal native to China,confined to some 30 fragmented habitat patches.Since giant pandas are long-lived,mature late,have lower reproductive rates,and show little sexual dimorphism,obtaining data to perform adequate PVA has been difficult.Here,we develop a parameter sensitivity index by modeling the dynamics of six giant panda populations in the Minshan Mountains,in order to determine the parameters most influential to giant panda populations.Our data shows that the giant panda populations are most sensitive to changes in four female parameters:initial breeding age,reproductive rate,mortality rate between age 0 and 1,and mortality rate of adults.The parameter sensitivity index strongly correlated with initial population size,as smaller populations were more sensitive to changes in these four variables.This model suggests that demographic parameters of females have more influence on the results of PVA,indicating that females may play a more important role in giant panda population dynamics than males.Consequently,reintroduction of female individuals to a small giant panda population should be a high priority for conservation efforts.Our findings form a technical basis for the coming program of giant panda reintroduction,and inform which parameters are crucial to successfully and feasibly monitoring wild giant panda populations. | Minghao GONG Yanling SONG Zhisong YANG Chen LIN | 2012 | Zoological Research2012，33，3： | 3 |
| 12 | Appearance manifolds for modeling time-variant appearance of materials显示文摘 | Jiaping Wang Xin Tong Stephen Lin Minghao Pan Chao Wang Hujun Bao Baining Guo Heung-Yeung Shum | 2006 | ACM Transactions on Graphics (TOG)2006，，3： | 2 |
| 13 | Dating of two thermokarst lakes in Beiluhe Basin, Qinghai-Tibetan Plateau显示文摘Most of the thermokarst lakes are spread appreciably in Beiluhe Basin,Qinghai-Tibet Plateau,China,where ice-rich permafrost exists.Two typical thermokarst lakes with differing area and depth were examined to ascertain their age.We obtained lake-bottom samples of 50 cm length from lake BLH-A and 25 cm length from lake BLH-B.Environmental 137 Cs and 210 Pb and radiocarbon age dating techniques were applied to the 50 cm and 25 cm samples,respectively.The results indicate that the initiation of BLH-A is about 800–900 a B.P.,and approximately 1,450±30 a B.P.to 2,230±30 a B.P.for BLH-B.These results will provide scientific bases for sedimentological study and thermokarst activity in Beiluhe Basin. | ZhanJu Lin FuJun Niu Jing Luo MingHao Liu GuoAn Yin | 2014 | Research in Cold and Arid Regions2014，6，5： | 1 |
| 14 | MHC-mismatched mice liver transplantation promotes tumor growth in liver graft显示文摘 | Sheng Yan Yuan Ding Yang Tian Zhongjie Lu Yan Wang Qiyi Zhang Yufu Ye Lin Zhou Haiyang Xie Hui Chen Minghao Zheng Shusen Zheng | 2014 | Cancer Letters2014，，： | 1 |
| 15 | In-situ selective surface engineering of graphene micro-supercapacitor chips显示文摘Surface modification of graphene oxide(GO)is a powerful strategy to develop its energy density for electrochemical energy storage.However,pre-modified GO always exhibits unsatisfactory hydrophilia and its ink-relevant utilization is extremely limited.Although GO ink is widely utilized in fabricating micro energy storage devices via extrusion-based 3D-printing,simultaneously obtaining satisfactory hydrophilia and high energy density still remains a challenge.In this work,an in-situ surface engineering strategy was employed to enhance the performance of GO micro-supercapacitor chips.Three dimensionally printed GO micro-supercapacitor chips were treated with pyrrole monomer to achieve selective and spontaneous anchoring of polypyrrole on the microelectrodes without affecting interspaces between the finger electrodes.The interface-reinforced graphene scaffolds were edge-welded and exhibited a considerably improved specific capacitance,from 13.6 to 128.4 mF·cm^(-2).These results are expected to provide a new method for improving the performance of micro-supercapacitors derived from GO inks and further strengthen the practicability of 3D printing techniques in fabricating energy storage devices. | Yiming Chen Minghao Guo Lin Xu Yuyang Cai Xiaocong Tian Xiaobin Liao Zhaoyang Wang Jiashen Meng Xufeng Hong Liqiang Mai | 2022 | Nano Research2022，15，2： | 0 |
| 16 | Mapless navigation for UAVs via reinforcement learning from demonstrations显示文摘This paper is concerned with the problems of mapless navigation for unmanned aerial vehicles in the scenarios with limited sensor accuracy and computing capability.A novel learning-based algorithm called soft actor-critic from demonstrations(SACfD)is proposed,integrating reinforcement learning with imitation learning.Specifically,the maximum entropy reinforcement learning framework is introduced to enhance the exploration capability of the algorithm,upon which the paper explores a way to sufficiently leverage demonstration data to significantly accelerate the convergence rate while improving policy performance reliably.Further,the proposed algorithm enables an implementation of mapless navigation for unmanned aerial vehicles and experimental results show that it outperforms the existing algorithms. | YANG JiaNan LU ShengAo HAN MingHao LI YunPeng MA YuTing LIN ZeFeng LI HaoWei | 2023 | Science China(Technological Sciences)2023，66，5： | 0 |
| 17 | Improving performance of ZnO Schottky photodetector by inserting MXenes modified-layer显示文摘The development of low-cost and high-performance ZnO Schottky photodetectors (PDs) has drawn intensive attention,but still a challenge due to their poor conductivity and low light utilization efficiency.Here,we introduce Ti_(3)C_(2)T_(X) into ZnO films to fabricate Schottky UV PDs via facile spin-coated method.The fabricated ZnO/Ti_(3)C_(2)T_(X)/ZnO compound film shows outstanding performance on photocurrent,responsivity,noise equivalent power (NEP),normalized detection rate (D~*),and linear dynamic region (LDR),compared with the original Zn O device.The photocurrent is significantly increased by 466%,and the responsivity is improved by one order of magnitude.In addition,it exhibits relatively low NEP (5.99×10^(-11)W),strong D~*(2.53×10~9 Jones),and high LDR (28 dB).The superior performance is ascribed to the enhanced conductivity and light absorption of ZnO film after introduction of Ti_(3)C_(2)T_(X) modification layer,leading to simultaneously faster electron transfer,lower the radiation recombination of electron and holes on the ZnO/Ti_(3)C_(2)T_(X)/ZnO compound film.This work provides a facile way to develop low-cost and highperformance ZnO Schottky PDs. | Cheng Wu Xinzhi Luo Xiaoming Yu Xuan Yu Kun Lin Minghao Li Zhenhua Li Yu Cao Yingtang Zhou | 2023 | Chinese Chemical Letters2023，34，7： | 0 |
| 18 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 19 | Curcumin inhibits colorectal cancer development by blocking the YAP/TAZ signaling axis显示文摘Background:Curcumin is a plant polyphenol with antitumor properties and inhibits the development of colorectal cancer(CRC).However,as the molecular mechanism associated is still unclear,our study aimed to explore the underlying molecular mechanisms by which curcumin inhibits CRC.Methods:HT29 and SW480 cells were treated with curcumin or/and Doxycycline(DOX),and cell viability,colony forming ability,migration and invasion were confirmed by cell counting kit-8(CCK-8),colony forming,Transwell assays.And Yes-associated protein 1(YAP)and PDZ-binding motif(TAZ)signaling-related genes or proteins were analyzed using reverse transcription quantitative real-time PCR(RT-qPCR),western blot,and immunofluorescence assays.Then nude mice xenograft tumor model was constructed,YAP and Ki67 expressions were tested by immunohistochemistry(IHC)staining.Results:In our study,we proved that curcumin significantly inhibited the CRC cell viability,cell migration,and cell invasion abilities.In addition,curcumin inhibited YAP and Transcriptional coactivator with TAZ or the YAP/TAZ signaling axis in CRC cells.Further,in the nude mice model,curcumin treatment significantly decreased the size and weight of xenotransplant tumors.Conclusion:Therefore,curcumin significantly inhibited CRC development and invasion by regulating the YAP/TAZ signaling axis. | FEI SHA DAISHAN XIN JUN XU ZHIWEI ZHENG WENXIN LIN XIAORUI CAI FEI LIN MINGHAO ZHENG JIAOLING CHEN | 2024 | BIOCELL2024，48，3： | 0 |
| 20 | Current status and future perspective of natural killer cell therapy for cancer显示文摘Natural killer(NK)cells possess innate abilities to effectively eliminate cancer cells.However,because of difficulties of proliferation and easy to be induced dysfunction in the setting of cancer post NK cell therapy,the curative effect of NK cell infusion has been constrained and not been widely applicable in clinical practice.The rapid development of biotechnology has promoted the development of NK cell therapy for cancer treatment.In this review,we will provide a comprehensive analysis of the current status and future prospects of NK cell therapy for cancer,focusing on the biological characteristics of NK cells,as well as strategies to enhance their targeting capabilities and overcome tumor immune suppression within the microenvironment. | Xiangyu Zhao Minghao Lin Xiaojun Huang | 2023 | Medical Review2023，3，4： | 0 |
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