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| 1 | ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13显示文摘这研究的目的是在房间增长和肺腺癌的 autophagy 调查 apelin 的角色。在肺腺癌的 APJ 的在表示上被 immunohistochemistry 检测,当在肺癌症病人的血浆 apelin 水平被连接酶的 immunosorbent 试金测量时。我们的调查结果表明 apelin-13 显著地增加了 ERK1/2 的 phosphorylation, cyclin D1 的表示,联系微导管的蛋白质 1 轻链 3A/B (LC3A/B ) ,和 beclin1,并且证实 apelin-13 支持了 A549 房间增长并且经由 ERK1/2 发信号导致了 A549 房间 autophagy。而且,人的肺腺癌房间线 A549 的表面和光滑、光滑的 apelin-13 原因房间表面上有毛孔是在原子力量下面观察了显微镜学。这些结果建议 ERK1/2 发信号小径调停 apelin-13-induced 肺腺癌房间增长和 autophagy。在我们的试验性的条件下面,与 3-methyladenine 联系的 autophagy 不涉及房间增长。 | Li Yang Tao Su Deguan Lv FengXie Wei Liu Jiangang Cao Irshad Ali Sheikh Xuping Qin Lanfang Li Linxi Chen | 2014 | Acta Biochimica et Biophysica Sinica2014，46，2： | 15 |
| 2 | Comparison of breast-conserving surgery and mastectomy in early breast cancer using observational data revisited:a propensity score-matched analysis显示文摘Recent observational studies showed that breast-conserving surgery(BCS) resulted in superior survival compared to mastectomy in breast cancer patients. This study compared the clinical outcomes of BCS and mastectomy using propensity score(PS)matching analysis, which had advantages over conventional methods in reducing bias. Nonmetastatic breast cancer patients who underwent BCS and mastectomy were matched 1:1 based on their PS. We used the Kaplan-Meier method and Cox-regression model to estimate the treatment effects. A total of 2,866 patients with a median follow-up time of 67 months were included in the original study population. Although the mastectomy cohort(N=1,219) had more advanced disease compared to the BCS cohort(N=1,647), LRFS was similar between the two groups(93.8% vs. 92.4%, P>0.05). BCS(vs. mastectomy) was associated with improved DFS(73.8% vs. 58.7%, P<0.01) and CSS(91% vs. 78.2%, P<0.01) in the original population. In the PS-matched population(N=1,668), clinicopathological features were equally distributed between the two cohorts. BCS(vs. mastectomy) was not associated with improved DFS(70.7% vs. 66.9%, P>0.05) or CSS(87.5% vs. 84.9%, P>0.05). We found that PS methods reduce bias when estimating treatment effects using observational data. BCS and mastectomy show equivalent outcomes in nonmetastatic breast cancer patients. | Kai Chen Zihao Pan Liling Zhu Tingting Hu Min Peng Weijuan Jia Fengxi Su Shunrong Li Erwei Song | 2018 | Science China(Life Sciences)2018，61，12： | 12 |
| 3 | Introduction of a multicenter online database for non-metastatic breast cancer in China显示文摘Dear Editor,Breast cancer is now the most frequently diagnosed cancer and is the fifth leading cause of cancer-related death in Chinese women. Therefore, the burden of breast cancer in China is gradually increasing. According to figures released by the Chinese Cancer Center in 2018, the number of newly diagnostic breast cancer is about 278,900 cases, accounting for 16.51%of all women who were diagnosed with the first primary malignant tumors;and 66,000 cases of breast cancer died in 2014 (Chen et al., 2016). | Yaping Yang Jieqiong Liu Min Peng Fengxi Su Xiaoming Xie Zhenzhen Liu Jundong Wu Wei Wei Dongxian Zhou Weiwen Li Ailing Zhang Guosen Su Weixiong Yang Jishang Chen Dekui Ma Yongguang Cai Kai Chen Liling Zhu Qiang Liu Erwei Song | 2020 | Science China(Life Sciences)2020，63，9： | 4 |
| 4 | In pursuit of a flawless aphrodite:paving the way to scarless oncoplastic breast surgery显示文摘Introduction Breast cancer is the most commonly diagnosed malig-nancy in women worldwide[1,2]and in the twentieth century,mastectomy was the primary surgical treatment for breast cancer patients.Advances in breast-conserving surgery(BCS)propelled a change in treatment rational from“maximum tolerable”to“minimum effective”ther-apy.Oncoplastic breast surgery aims to restore the shape of the breast and has been widely adopted since the past decade.Although the cosmetic outcome has been sig-nificantly improved,the scar remaining on the surgeried breast skin is still a major pitfall that urges urgent consid-eration.In this editorial,we review a series of techniques that can be incorporated in oncoplastic breast surgery to minimize scarring,signifying the beginning of an era for scarless oncoplastic surgery. | Liling Zhu Shunrong Li Luyuan Tan Xiaolan Zhang Jiannan Wu Fengxi Su Kai Chen Erwei Song | 2019 | Cancer Communications2019，39，1： | 4 |
| 5 | A Positive Feedback Loop between Mesenchymal-like Cancer Cells and Macrophages Is Essential to Breast Cancer Metastasis显示文摘 | Shicheng Su Qiang Liu Jingqi Chen Jianing Chen Fei Chen Chonghua He Di Huang Wei Wu Ling Lin Wei Huang Jin Zhang Xiuying Cui Fang Zheng Haiyan Li Herui Yao Fengxi Su Erwei Song | 2014 | Cancer Cell2014，，5： | 3 |
| 6 | 比较B超定位和常规体表定位法静脉输液港植入术在乳腺癌患者中的应用(英文)显示文摘Objective:The aim of this study was to compare the anatomic-landmark and ultrasound-guided techniques in the placement of an internal jugular vein port in patients with advanced breast cancer.Methods:Between March 2010 and October 2010,60 patients with advanced breast cancer underwent central venous port placement for the delivery of chemotherapy,preferably through the internal jugular vein.Patients were randomly assigned to either the anatomic-landmark or the ultrasound-guided group.Failure on first attempt,number of attempts until successful catheterization,time to successful placement,the accordance of the two placement approaches,and the demographics of each patient were recorded.Results: The consistency of the direction of two lines drawn using the anatomic-landmark and ultrasound-guided techniques or of the diameter of the internal jugular vein as determined by the two approaches was 85%(51/60).The rate of successful placement at first attempt was higher in the ultrasound group than in the anatomic-landmark group(P<0.05).A greater number of attempts and longer time to successful port placement were needed in the latter(P<0.05).Conclusion:The findings of this study indicate that,in the placement of an internal jugular vein port,the ultrasound(US)-guided technique has several advantages over the anatomic-landmark technique. | Nanyan Rao Jiannan Wu Shunrong Li Liang Jin Weijuan Jia Heran Deng Fengxi Su | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，12： | 2 |
| 7 | Strong solutions of SDE driven by countably many Brownian motions显示文摘 | ZONG Fengxi LI Rubing | 2010 | Jour-nal of Yunnan University o{ Nationalities2010，19，5： | 1 |
| 8 | Properties of countably many Brownian motions显示文摘 | ZONG Fengxi LI Rubing | 2009 | Journal of Shandong Nor real University2009，24，2： | 1 |
| 9 | Synthesis of MCM-48 Using Mixed Cationic-Anionic Surfactants as Tem- plates显示文摘 | Chen Fengxi Huang Liming Li Quanzhi | 1997 | Chem Mater1997，9，12： | 1 |
| 10 | Effect of Hydro- thermal Conditions on the Synthesis of Siliceous MCM-48 in Mixed Cationic-Anionic Surfactants Systems 显示文摘 | Chen Fengxi Yan Xuewu Li Quanzhi | 1998 | Stud SurfSci Catal1998，117，： | 1 |
| 11 | Mixed Cationic- Anionic Templating Route to A1-MCM-48 显示文摘 | Chen Fengxi Song Fubing Li Quanzhi | 1999 | Microporous MesoporousMater1999，29，3： | 1 |
| 12 | A method for speeding up feature extraction based on KPCA显示文摘 | Yong Xu David Zhang Fengxi Song Jing-Yu Yang Zhong Jing Miao Li | 2006 | Neurocomputing2006，，4： | 1 |
| 13 | Research Progress on the Bismuth Containing Complex Oxide in Photocatalystic Technology显示文摘The photocatalytic degradation on the bismuth containing complex oxide was revised in detail including the synthesis and classification of photocatalyts,and then the photocatalytic reaction,scavenger,and the mechanism of reaction. In particular,the perspectives of photocatalytic degradation on the bismuth containing oxide were analyzed in detail. | Miao Yingchun Yang Huiqiong Li Fengxi Liang Yiwei | 2015 | Meteorological and Environmental Research2015，6，5： | 0 |
| 14 | Genome-wide association analysis identified molecular markers and candidate genes for flower traits in Chinese orchid (Cymbidium sinense)显示文摘The orchid,the champagne of f lowers,brings luxury,elegance,and novelty to nature.Cymbidium sinense is a symbol of gigantic floral variability on account ofwavering shapes and sizes of f loral organs,althoughmarker-trait association(MTA)has not been studied for its f loral traits.We evaluated markers associated with 14 f loral traits of C.sinense through a genome-wide association study(GWAS)of 195 accessions.A total of 65318522 single-nucleotide polymorphisms(SNPs)and 3906176 insertion/deletion(InDel)events were identified through genotyping-by-sequencing.Among these,4694 potential SNPs and 477 InDelswere identified as MTAs at−log10 P>5.The genes related to these SNPs and InDels were largely associated with f loral regulators,hormonal pathways,cell division,and metabolism,playing essential roles in tailoring f loral morphology.Moreover,20 candidate SNPs/InDels linked to 11 genes were verified,8 of which were situated on exons,onewas located in the 5-UTR and twowere positioned in introns.Here,themultitepal trait-related gene RABBIT EARS(RBE)was found to be the most crucial gene.We analyzed the role of CsRBE in the regulation of flower-related genes via efficient transient overexpression in C.sinense protoplasts,and found that the floral homeotic genes CsAP3 and CsPI,as well as organ boundary regulators,including CsCUC and CsTCP genes,were regulated by CsRBE.Thus,we obtained key gene loci for important ornamental traits of orchids using genome-wide association analysis of populations with natural variation.The findings of this study can do a great deal to expedite orchid breeding programs for shape variability. | Fengxi Yang Yudi Guo Jie Li Chuqiao Lu Yonglu Wei Jie Gao Qi Xie Jianpeng Jin Genfa Zhu | 2023 | Horticulture Research2023，10，11： | 0 |
| 15 | 细胞浆中与NF-KB相互作用的长非编码RNA NKILA通过调控IkB磷酸化抑制乳腺癌转移显示文摘细胞出版社《癌细胞》杂志创刊于2002年,其旨在出版具有高影响力的癌症研究论文。《癌细胞》每年出版12期,每期正式出版前会选择部分文章提前在线出版。该杂志2015年公布的影响因子为23.523。 | Bodu Liu Lijuan Sun Qiang Liu Chang Gong Yandan Yao Xiaobin Lv Ling Lin Herui Yao Fengxi Su Dangsheng Li Musheng Zeng 宋尔卫 | 2016 | 科学新闻2016，0，1： | 0 |
| 16 | Astragalus injection as an adjuvant treatment for colorectal cancer:a meta-analysis显示文摘Background:The combination of Chinese patent medicine Astragalus injection and Western medicine has achieved a certain clinical effect in colorectal cancer patients.However,due to the uneven basic conditions and research indicators of these clinical trials,it is difficult to comprehensively evaluate the effect of Astragalus injection in the adjuvant treatment of colorectal cancer.This study aimed to systematically evaluate the efficacy and safety of Astragalus injection as an adjuvant treatment for colorectal cancer.Methods:The Cochrane Library,VIP database,Wanfang database,and Chinese Academic Journal Full Text database were searched for potentially eligible articles from inception to December 15,2018.Randomized controlled trials in which patients were diagnosed with colorectal cancer were included.Patients in the control group received chemotherapy alone or combined with other drugs,or chemotherapy combined with radiotherapy.Patients in the experimental group were treated with Astragalus injection combined with interventions in the control group.Results:A total of 8 articles were included.Compared with Western medicine alone,the Astragalus injection could improve the therapeutic effect(RR=1.18,95%CI(1.01,1.38),P=0.03),improved the quality of life of colorectal cancer patients(SMD=1.18,95%CI(0.86,1.50),P<0.001),inhibited leukopenia(RR=0.55,95%CI(0.42,0.71),P<0.001),reduced neurotoxicity(RR=0.43,95%CI(0.34,0.56),P<0.001),and reduced the incidence of nausea and vomiting(RR=0.67,95%CI(0.55,0.80),P<0.001).Conclusion:Astragalus injection can reduce the toxicity and improve the efficiency of the conventional Western medicine in the treatment of colorectal cancer. | Jia Wang Zhu Yang Fengxi Long Li Luo Jinlin Wu Ting Yu Dongxin Tang | 2020 | Traditional Medicine Research2020，5，1： | 0 |
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