|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Risk factors and clinical responses of pneumonia patients with colistin-resistant Acinetobacter baumannii-calcoaceticus显示文摘BACKGROUND Nosocomial infections with carbapenem-resistant Acinetobacter baumanniicalcoaceticus complex(ABC)strains are great problem for intensive care units.ABC strains can develop resistance to all the antibiotics available.Carbapenem resistance is common and colistin resistance is rare in our country.Knowing the risk factors for colistin resistance is important since colistin seems to be the only remaining therapeutic option for the patients with pneumonia due to extensively drug resistant ABC for our country.AIM To investigate the comparison of clinical responses and outcomes between pneumonia patients with colistin-susceptible and-resistant Acinetobacter sp.Strains.METHODS During the study period,108 patients with pneumonia due to colistin-susceptible strains and 16 patients with colistin-resistant strains were included retrospectively.Continuous variables were compared with the Mann-Whitney U test,and categorical variables were compared using Pearson’s chi-square test or Fisher’s Exact chi-square test for two groups.A binary logistic regression model was developed to identify the potential independent factors associated with colistin resistance in patients with colistin-resistant strains.RESULTS High Acute Physiology and Chronic Health Evaluation II scores(OR=1.9,95%CI:1.4-2.7;P<0.001)and prior receipt of teicoplanin(OR=8.1,95%CI:1.0-63.3;P=0.045)were found to be independent risk factors for infection with colistin-resistant Acinetobacter sp.Different combinations of antibiotics including colistin,meropenem,ampicillin/sulbactam,amikacin and trimethoprim/sulfamethoxazole were used for the treatment of patients with colistin-resistant strains.Although the median duration of microbiological cure(P<0.001)was longer in the colistin-resistant group,clinical(P=0.703),laboratory(P=0.277),radiological(P=0.551),microbiological response(P=1.000)and infection related mortality rates(P=0.603)did not differ between the two groups.Among the patients with infections due to colistin-resistant strains,seven were treated with antibiotic combinations that included sulbactam.Clinical(6/7)and microbiological(5/7)response rates were quite high in these patients.CONCLUSION The optimal therapy regimen is unclear for colistin-resistant Acinetobacter sp.infections.Although combinations with sulbactam seems to be more effective in our study patients,data supporting the usefulness of combinations with sulbactam is very limited. | Hande Aydemir Hande Idil Tuz Nihal Piskin Guven Celebi Canan Kulah Furuzan Kokturk | 2019 | World Journal of Clinical Cases2019，7，10： | 7 |
| 2 | Analysis of glomerular filtration rate, serum cystatin C levels, and renal resistive index values in cirrhosis patients显示文摘 | Yucel Ustundag Ufuk Samsar Sereften Acikgoz Mehmet Cabuk Sibel Kiran Eyup Kulah Selim Aydemir | 2007 | Clinical Chemical Laboratory Medicine2007，，7： | 2 |
| 3 | Noise analysis and characterization of a sigma-delta capacitive microaccelerometer显示文摘 | KULAH H CHAE J YAZDI N | 2006 | IEEE Journal of solid-state Circuits2006，41，2： | 1 |
| 4 | A Current Mirroring Integration Based Readout Circuit for High Performance Infrared FPA Applications显示文摘 | Kulah H Akin T | | 0，，： | 1 |
| 5 | Presentation and outcome of incarcerated external hernias in adults显示文摘 | Kulah B Kulacoglu H Oruc T | 2001 | Am J Surg2001，181，2： | 1 |
| 6 | Analysis of glomerular filtration rate, serum cystatin C levels, and renal resistive index values in cirrhosis patients显示文摘 | Yucel Ustundag Ufuk Samsar Sereften Acikgoz Mehmet Cabuk Sibel Kiran Eyup Kulah Selim Aydemir | 2007 | Clinical Chemical Laboratory Medicine2007，，7： | 1 |
| 7 | Dimethyl sulfoxide in the management of patient with brain swelling and increased intracranial pressure after severe closed head injury显示文摘 | Kulah A Akar M Baykut L | 1990 | Neurochirurgia (Stuttg)1990，33，6： | 1 |
| 8 | Clinical Consequences ofIntermittent Elevation of C-reactive Protein Levels in Hemodial-ysis Patients显示文摘 | Sezer S Kulah E Ozdemir FN et a1 | 2004 | Transplant Proc2004，36，1： | 1 |
| 9 | Emergency hernia repairs in elderly patients 显示文摘 | Kulah B Duzgun AP Moran M | 2001 | Am J Surg2001，182，5： | 1 |
| 10 | Cystic meningiomas显示文摘 | Kulah A Ilcayto R Fiskeci C | 1991 | Acta Neurochir(Wien)1991，111，： | 1 |
| 11 | Modeling of a capacitive S-A MEMS accelerometer system including the noise components and verification with test result显示文摘 | Boga B Ocak I E Kulah H | | 0，，： | 1 |
| 12 | Presentation and out- come of incarcerated external hernias in adults 显示文摘 | Kulah B Kulacoglu IH Oruc MT | 2001 | Am J Surg2001，181，2： | 1 |
| 13 | Pericardial tamponade and systemic sclerosis显示文摘 | Keskin G Kulah E Turgay M | 1996 | Clin Exp Rheumatol1996，14，6： | 1 |
| 14 | Emergency hemia repairs in elderly patients 显示文摘 | Kulah B Duzgun AP Moran M | 2001 | Am J Surg2001，182，5： | 1 |
| 15 | The relationship of target organ damage and 24-hour ambulatory blood pressure monitoring with vitamin D receptor gene Fok-? polymorphism in essential hypertension 显示文摘 | Kulah E Dursun A Acigoz S | 2006 | Kid Blood Press Res2006，29，6： | 1 |
| 16 | Effects of angiotensin converting enzyme gene polymorphism and serum vitamin D levels on ambulatory blood pressure measurement and left ventricular mass in Turkish hypertensive population 显示文摘 | Kulah E Dursun A Aktunc E | 2007 | Blood Press Monit2007，12，4： | 1 |
| 17 | Presentation and outcome of incarcerated external hernias in adults显示文摘 | KULAH B KULACOGLU IH ORUC MT | 2001 | Am J Surg2001，181，2： | 1 |
| 18 | Emergency hernia repairs in elderly patients显示文摘 | KULAH B POLAT-DUZGUN A MORAN M | 2001 | Am J surg2001，182，5： | 1 |
| 19 | Noise analysis and characterization of a sigma-delta capacitive microac- celerometer 显示文摘 | Haluk Kulah Junseok Chae Khalil Najafi | 2006 | IEEE Journal of Solid-State Circuits2006，41，2： | 1 |
| 20 | Outcomes of emergency surgical treatment in malignant bowel obstructions 显示文摘 | Kulah B Ozmen M Ozer MV | 2005 | Hepatogastroenterology2005，52，64： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员