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您的检索式：作者名="Guven Celebi"
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| 1 | Risk factors and clinical responses of pneumonia patients with colistin-resistant Acinetobacter baumannii-calcoaceticus显示文摘BACKGROUND Nosocomial infections with carbapenem-resistant Acinetobacter baumanniicalcoaceticus complex(ABC)strains are great problem for intensive care units.ABC strains can develop resistance to all the antibiotics available.Carbapenem resistance is common and colistin resistance is rare in our country.Knowing the risk factors for colistin resistance is important since colistin seems to be the only remaining therapeutic option for the patients with pneumonia due to extensively drug resistant ABC for our country.AIM To investigate the comparison of clinical responses and outcomes between pneumonia patients with colistin-susceptible and-resistant Acinetobacter sp.Strains.METHODS During the study period,108 patients with pneumonia due to colistin-susceptible strains and 16 patients with colistin-resistant strains were included retrospectively.Continuous variables were compared with the Mann-Whitney U test,and categorical variables were compared using Pearson’s chi-square test or Fisher’s Exact chi-square test for two groups.A binary logistic regression model was developed to identify the potential independent factors associated with colistin resistance in patients with colistin-resistant strains.RESULTS High Acute Physiology and Chronic Health Evaluation II scores(OR=1.9,95%CI:1.4-2.7;P<0.001)and prior receipt of teicoplanin(OR=8.1,95%CI:1.0-63.3;P=0.045)were found to be independent risk factors for infection with colistin-resistant Acinetobacter sp.Different combinations of antibiotics including colistin,meropenem,ampicillin/sulbactam,amikacin and trimethoprim/sulfamethoxazole were used for the treatment of patients with colistin-resistant strains.Although the median duration of microbiological cure(P<0.001)was longer in the colistin-resistant group,clinical(P=0.703),laboratory(P=0.277),radiological(P=0.551),microbiological response(P=1.000)and infection related mortality rates(P=0.603)did not differ between the two groups.Among the patients with infections due to colistin-resistant strains,seven were treated with antibiotic combinations that included sulbactam.Clinical(6/7)and microbiological(5/7)response rates were quite high in these patients.CONCLUSION The optimal therapy regimen is unclear for colistin-resistant Acinetobacter sp.infections.Although combinations with sulbactam seems to be more effective in our study patients,data supporting the usefulness of combinations with sulbactam is very limited. | Hande Aydemir Hande Idil Tuz Nihal Piskin Guven Celebi Canan Kulah Furuzan Kokturk | 2019 | World Journal of Clinical Cases2019，7，10： | 7 |
| 2 | Plasma concentrations of13,14-dihydro-15-keto PGF 2 and progesterone during the oviposition cycle of the domestic goose(Anser anser domesticus)显示文摘 | Celebi F Guven B | 2001 | Poultry Science2001，80，： | 1 |
| 3 | Plasma concentrations of 13,14-dihydro- 15-keto PGF2alpha and progesterone during the oviposition cy- cle of the domestic goose (Anser anser domesticus)显示文摘 | Celebi F Guven B | 2001 | Poultry Science2001，80，： | 1 |
| 4 | Diclofenac suppository administration in conjunction with lidocaine gel during transrectal ultrasound-guided prostate biopsy: Prospective, randomized, placebo-controlled study显示文摘 | Bora Irer Aytac Gulcu Guven Aslan Yigit Goktay Ilhan Celebi | 2005 | Urology2005，，4： | 1 |
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