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| 1 | Progression of remnant gastric cancer is associated with duration of follow-up following distal gastrectomy显示文摘AIM: To re-evaluate the recent clinicopathological features of remnant gastric cancer (RGC) and to develop desirable surveillance programs. METHODS: Between 1997 and 2008, 1149 patients underwent gastrectomy for gastric cancer at the Department of Digestive Surgery, Kyoto Prefectural University of Medicine, Japan. Of these, 33 patients underwent gastrectomy with lymphadenectomy for RGC. Regarding the initial gastric disease, there were 19 patients with benign disease and 14 patients with gastric cancer. The hospital records of these patients were reviewed retrospectively. RESULTS: Concerning the initial gastric disease, the RGC group following gastric cancer had a shorter interval [P < 0.05; gastric cancer vs benign disease: 12 (2-22) vs 30 (4-51) years] and were more frequently reconstructed by Billroth-Ⅰ procedure than those following benign lesions (P < 0.001). Regarding reconstruction, RGC following Billroth-Ⅱ reconstruction showed a longer interval between surgical procedures [P < 0.001; Billroth-Ⅱ vs Billroth-Ⅰ: 32 (5-51) vs 12 (2-36) years] and tumors were more frequently associated with benign disease (P < 0.001) than those following Billroth-Ⅰ reconstruction. In tumor location of RGC, after Billroth-Ⅰ reconstruction, RGC occurred more frequently near the suture line and remnant gastric wall. After Billroth-Ⅱ reconstruction, RGC occurred more frequently at the anastomotic site. The duration of follow-up was significantly associated with the stage of RGC (P < 0.05). Patients diagnosed with early stage RGC such as stage Ⅰ-Ⅱ tended to have been followed up almost every second year. CONCLUSION: Meticulous follow-up examination and early detection of RGC might lead to a better prognosis. Based on the initial gastric disease and the procedure of reconstruction, an appropriate follow-up interval and programs might enable early detection of RGC. | Shuhei Komatsu Daisuke Ichikawa Kazuma Okamoto Daito Ikoma Masahiro Tsujiura Yukihisa Nishimura Yasutoshi Murayama Atsushi Shiozaki Hisashi Ikoma Yoshiaki Kuriu Masayoshi Nakanishi Hitoshi Fujiwara Toshiya Ochiai Yukihito Kokuba Eigo Otsuji | 2012 | World Journal of Gastroenterology2012，18，22： | 25 |
| 2 | Surgical treatment of hepatocellular carcinoma with severe intratumoral arterioportal shunt显示文摘We report a case of hepatocellular carcinoma (HCC) that caused a severe arterioportal shunt (APS). A 49-year-old man was admitted to hospital due to esophagogastric variceal hemorrhage and HCC, and underwent endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS). He was then referred to our hospital. Abdominal computed tomography revealed a lowdensity lesion in the posterior segment of the liver and an intratumoral APS, which caused portal hypertension. Although the patient underwent EVL, EIS, Hassab’s operation, and transcatheter arterial embolization for APS, he vomited blood due to rupture of esophagogastric varices. Right hepatectomy was performed for the treatment of HCC and APS, although the indocyanine green retention value at 15 min after intravenous injection was poor (30%). The patient’s postoperative course was uneventful. Eventually, APS disappeared and the esophagogastric varices improved. | Hiromichi Ishii Teruhisa Sonoyama Shingo Nakashima Hiroyuki Nagata Atsushi Shiozaki Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Daisuke Ichikawa Hitoshi Fujiwara Kazuma Okamoto Toshiya Ochiai Yukihito Kokuba Chohei Sakakura Eigo Otsuji | 2010 | World Journal of Gastroenterology2010，16，25： | 11 |
| 3 | Differences of the Lymphatic Distribution and Surgical Outcomes Between Remnant Gastric Cancers and Primary Proximal Gastric Cancers显示文摘 | Shuhei Komatsu Daisuke Ichikawa Kazuma Okamoto Daito Ikoma Masahiro Tsujiura Atsushi Shiozaki Hitoshi Fujiwara Yasutoshi Murayama Yoshiaki Kuriu Hisashi Ikoma Masayoshi Nakanishi Toshiya Ochiai Yukihito Kokuba Eigo Otsuji | 2012 | Journal of Gastrointestinal Surgery2012，，3： | 2 |
| 4 | Molecular analysis of a novel hereditary C3 deficiency with systemic lupus erythematosus显示文摘 | TSUKAMOTO H HORIUCHI T KOKUBA H | 2005 | Biochem Biophys Res Commun2005，330，1： | 1 |
| 5 | Surgical resection of stage Ⅳ colorectal cancer and prognosis显示文摘 | Katoh H Yamashita K Kokuba Y | 2008 | World J Surg2008，32，6： | 1 |
| 6 | A case report of metastatic neuroendocrine carcinoma of the right adrenal gland successfully treated with chemotherapy and surgery显示文摘 | Toshiya Ochiai Sosuke Komiyama Hisashi Ikoma Takeshi Kubota Masayoshi Nakanishi Daisuke Ichikawa Shojiro Kikuchi Hitoshi Fujiwara Chohei Sakakura Yukihito Kokuba Teruhisa Sonoyama Eigo Otsuji | 2010 | International Journal of Clinical Oncology2010，，4： | 1 |
| 7 | Phase I trial of neoadjuvant preopera- tive chenmtherapy with S - 1 and irinotecan plus radiation in patients with locally advanced rectal cancer显示文摘 | Sato T Kokuba Y Koizumi W | 2007 | Int J Radiat Oneol Biol Phys2007，69，5： | 1 |
| 8 | Surgical resection of stage Ⅳ colorectal cancer and prognosis显示文摘 | Katoh H Yamashita K Kokuba Y | | 0，，06： | 1 |
| 9 | White blood cell count,C-reactive protein and erythrocyte sedimention rate in respiratory syncytial virus infection of the lower respiratory tract显示文摘 | Sai JoM Ishii T Kokuba M | 1996 | Acta Paediatr Jpn1996，38，6： | 1 |
| 10 | Neoadjuvantchemoradio- therapy for locally advanced rectal cancer 显示文摘 | Kuriu Y Kokuba Y Murayama Y | 2012 | Gan To Kagaku Ryoho2012，39，12： | 1 |
| 11 | Production of haploid plant by anther culture of setaria italica显示文摘 | Ben Y Kokuba T Miyaji Y | 1971 | Bull Fac Agric Kogoshima Univ1971，21，： | 1 |
| 12 | Effect of D-methionine-containing solution on tumor cell growth in vitro显示文摘 | Sasamura T Matsuda A Kokuba Y | 1999 | Arzneimittelforschung1999，49，6： | 1 |
| 13 | Bullous pemphigoidfollowed by pustular psori肪is showing Thl, Th2, Treg and TTil7immunological changes显示文摘 | Yasukawa S Dainichi T Kokuba H | 2009 | Eur J Dermatol2009，19，1： | 1 |
| 14 | Tumor growth inhibition and nutritional effect of D-amino acid solution in AH109A hepatomabearing rats显示文摘 | Sasamura T Matsuda A Kokuba Y | 1998 | J Nutr Sci Vitaminol1998，44，1： | 1 |
| 15 | Phase Ⅰ trial of neoadjuvant preoperative chemotherapy with S-1 and irinotecan plus radiation in patients with locally advanced rectal cancer显示文摘 | Sato T Kokuba Y Koizumi W | | 0，，： | 1 |
| 16 | Short-term outcomes of laparoscopic intersphincteric resection from a phase II trial to evaluate laparoscopic surgery for stage 0/I rectal cancer: Japan Society of Laparoscopic Colorectal Surgery Lap RC显示文摘 | Shoichi Fujii Seiichiro Yamamoto Masaaki Ito Shigeki Yamaguchi Kazuhiro Sakamoto Yusuke Kinugasa Yukihito Kokuba Junji Okuda Kenichi Yoshimura Masahiko Watanabe | 2012 | Surgical Endoscopy2012，，11： | 1 |
| 17 | Tumor growth inhibition and nutritional effect of D-amino acid solution in AH109A hepatoma- bearing rats显示文摘 | Sasamura T Matsuda A Kokuba Y | 1995 | Nutr Sci Vitaminol Tokyo1995，44，1： | 1 |
| 18 | Nutritional effects of a D- Methionine-containing solution on AH109A hepatoma-bearing rats 显示文摘 | Sasamura T Matsuda A Kokuba Y | 1998 | Biosci Biotechnol Biochem1998，62，12： | 1 |
| 19 | Effects of D-methionine-containing solution on tumor cell growth in vitro 显示文摘 | Sasamura T Matsuda A Kokuba Y | 1999 | Arzneimittelforschung1999，49，： | 1 |
| 20 | Case of diabetic scleredema: diagnostic value of magnetic resonance imaging 显示文摘 | Kurihara Y Kokuba H Furue M | 2011 | J Dermatol2011，38，7： | 1 |
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