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| 1 | Neoatherosclerosis:Coronary stents seal atherosclerotic lesions but result in making a new problem of atherosclerosis显示文摘Chronic inflammation of the native vessel wall with infiltration of lipid-laden foamy macrophages through impaired endothelium results in atherosclerosis. Percutaneous coronary intervention, including metallic stent implantation, is now widely utilized for the treatment of atherosclerotic lesions of the coronary artery. Baremetal stents and the subsequently developed drugeluting stents seal the atherosclerosis and resolve lumen stenosis or obstruction of the epicardial coronary artery and myocardial ischemia. After stent implantation, neointima proliferates within the stented segment. Chronic inflammation caused by a foreign body reaction to the implanted stent and subsequent neovascularization, which is characterized by the continuous recruitment of macrophages into the vessel, result in the transformation of the usual neointima into an atheromatous neointima. Neointima with an atherosclerotic appearance, such as that caused by thin-cap fibroatheromas, is now recognized as neoatherosclerosis, which can sometimes cause in-stent restenosis and acute thrombotic occlusion originating from the stent segment following disruption of the atheroma. Neoatherosclerosis is emerging as a new coronary stent-associated problem that has not yet been resolved. In this review article, we will discuss possible mechanisms, clinical challenges, and the future outlook of neoatherosclerosis. | Hidenori Komiyama Masamichi Takano Noritake Hata Yoshihiko Seino Wataru Shimizu Kyoichi Mizuno | 2015 | World Journal of Cardiology2015，7，11： | 7 |
| 2 | Visualization of flashback in a premixed burner with swirling flow显示文摘In this study,the measurement object is a flame propagating in a premixed burner with swirling flow in order to investigate unsteady flame behavior in a gas turbine premixer.During flashback,the flame propagating upstream was visualized with a high-speed camera.Moreover,we established the technique to measure the instantaneous flow fields of unburned fuel-air mixture in a swirling premixed burner using particle image velocimetry(PIV).As a result,the characteristics of flame behavior propagating upstream were examined.And it was found that a low velocity region existed in the vicinity of the flame tip.The relationship between low velocity region and flame behavior was discussed in detail. | Satoshi TANIMURA Masaharu KOMIYAMA Kenichiro TAKEISHI Yuji IWASAKI Kiyonobu NAKAYAMA | 2010 | Science China(Technological Sciences)2010，53，1： | 4 |
| 3 | Percoll fractionation of adult mouse spermatogonia improvesgerm cell transplantation显示文摘Aim: To isolate and transplant germ cells from adult mouse testes for transplantation. Methods: In order to distinguish transplanted cells from endogenous cells of recipients, donor transgenic mice expressing green fluorescent protein (GFP) were used. Germ cells were collected from the donors at 10-12 weeks of age and spermatogonia were concentrated by percoll fractionation and transplanted into recipient seminiferous tubules that had been previously treated with busulfan at 5 weeks of age to remove the endogenous spermatogenic cells. Results: Twenty weeks after the transplantation, a wide spread GFP signal was observed in the recipient seminiferous tubules. The presence of spermatogenesis and spermatozoa was confirmed in sections of 12 out of 14 testes transplanted (86%).However, when germ cells were transplanted without concentration the success rate was zero (0/9). Conclusion:Germ cells from adult mouse testes can be successfully transplanted into recipient seminiferous tubules if the cell population is rich in spermatogonia and the percoll fractionation is useful in obtaining such a cell population. | Kyu-Bom Koh Masatoshi Komiyama Yoshiro Toyama Tetsuya Adachi Chisato Mori | 2004 | Asian Journal of Andrology2004，6，2： | 3 |
| 4 | Calculation of child and adult standard liver volume for liver transplantation显示文摘 | Koichi Urata Seiji Kawasaki Hidetoshi Matsunami Yasuhiko Hashikura Toshihiko Ikegami Shinpachi Ishizone Yoshitaka Momose Atsushi Komiyama Masatoshi Makuuchi | 1995 | Hepatology1995，，5： | 3 |
| 5 | Ileo-ileal intussusception caused by lymphangioma of the small bowel treated by single-incision laparoscopic-assisted ileal resection显示文摘Intraabdominal lymphangiomas are uncommon;additionally,those affecting the gastrointestinal tract are rare and account for less than 1%of cases.Intussusception caused by a cystic lymphangioma of the small bowel is extremely rare.The patient was a20-year-old woman who visited our emergency room with a complaint of abdominal pain.A computed tomography image revealed ileo-ileal intussusception with a leading hypovascular mass measuring 1 cm in a diameter.Single-incision laparoscopic-assisted ileal resection was performed.The surgical specimen consisted of a soft polycystic mass.Macroscopically,a pedunculated polyp with a convolutional pattern was found.Microscopically,the inner surfaces of the cysts were covered with a single layer of endothelial cells.On immunohistochemical examination,the endothelial cells were partially positive for D2-40 and CD34.Smooth muscle cells were also found around the cysts.The lesion was diagnosed as a cystic lymphangioma.Dozens of cases of small bowel lymphangiomas have previously been reported.Of these,cases with intussusception were very rare.This is the first case of small bowel intussusception due to lymphangioma treated by singleincision laparoscopic-assisted surgery. | Atsushi Kohga Akihiro Kawabe Yuto Hasegawa Kiyoshige Yajima Takuya Okumura Kimihiro Yamashita Jun Isogaki Kenji Suzuki Akira Komiyama | 2017 | World Journal of Gastroenterology2017，23，1： | 2 |
| 6 | Calculation of child and adult standard liver volume for liver transplantation显示文摘 | Koichi Urata Seiji Kawasaki Hidetoshi Matsunami Yasuhiko Hashikura Toshihiko Ikegami Shinpachi Ishizone Yoshitaka Momose Atsushi Komiyama Masatoshi Makuuchi | 1995 | Hepatology1995，，5： | 2 |
| 7 | Age-related diferences in proliferarive responses of Schwann cells during Wallerian degeneration 显示文摘 | Komiyama A Suzuki K | 1992 | Brain Res1992，573，2： | 1 |
| 8 | Hydrolysis of RNA and protein by rare earth metal ions显示文摘 | | 1995 | Taupkushitsu Kakusan Koso1995，40，7： | 1 |
| 9 | Tailor-made re- ceptors by molecular imprinting 显示文摘 | Asanuma H Hishiya T Komiyama M | 2000 | Advanced Materi- als2000，14，： | 1 |
| 10 | Age-related changes in attachment and proliferation of mouse Schwann cells in vitro 显示文摘 | Komiyama A Suzuki K | 1991 | Brain Res DevBrain Res1991，，： | 1 |
| 11 | Expression of secretory phospholipase A2s in human atherosclerosis development 显示文摘 | Kimura-Matsumoto M Ishikawa Y Komiyama K | 2008 | Atherosclerosis2008，196，1： | 1 |
| 12 | IL-17 plays an important role in the developmental autoimmune encephalom- yelitis显示文摘 | Komiyama YS Nakae T Matsuki A | 2006 | J Immunol2006，177，1： | 1 |
| 13 | 308-nm excimer lamp for the treatment of alopecia areata: clinical trial on 16 cases显示文摘 | Ohtsuki A Hasegawa T Komiyama E | 2013 | Indian J Dermatol2013，58，4： | 1 |
| 14 | IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis显示文摘 | Komiyama Y Nakae S Matsuki T | 2006 | J Immunol2006，177，1： | 1 |
| 15 | Local activation of TGF-betal at endometriosis sites 显示文摘 | Korniyama S Aoki D Komiyama M | 2007 | J Reprod Med2007，52，： | 1 |
| 16 | Development of Hybrid Power Train Control System for Exeavator显示文摘 | Kagoshima M Sora T Komiyama M | 2003 | JSAE2003，，： | 1 |
| 17 | IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis显示文摘 | Komiyama Y Nakae S Matsuki T | 2006 | J Immunol2006，177，1： | 1 |
| 18 | Selective permeation of metal ions through cation exchange membrane carrying N-(8-quinolyl)-sulfonamide as a chelating ligand显示文摘 | Kojima T Takano T Komiyama T | 1995 | J Membr Sci1995，102，12： | 1 |
| 19 | Long-Term Survival After Report Resection of Pulmonary Metastases from Hepatocellular Carcinoma: Report of Two Cases显示文摘 | Toru Nakamura Taizo Kimura Yasuhiko Umehara Kenji Suzuki Kazuya Okamoto Takuya Okumura Sei Morizumi Toshiki Kawabata Akira Komiyama | 2005 | Surgery Today2005，，10： | 1 |
| 20 | Hydrolysis of DNA and RNA by lanthanide ions: mechanistic studies leading to new applications显示文摘 | Komiyama M Takada N Shigekawa H | 1999 | Chemical Communications1999，，： | 1 |
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