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| 1 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 2 | The RppC-AvrRppC NLR-effector interaction mediates the resistance to southern corn rust in maize显示文摘Southern corn rust(SCR),caused by the fungal pathogen Puccinia polysora,is a major threat to maize pro-duction worldwide.Efficient breeding and deployment of resistant hybrids are key to achieving durable control of SCR.Here,we report the molecular cloning and characterization of RppC,which encodes an NLR-type immune receptor and is responsible for a major SCR resistance quantitative trait locus.Further-more,we identified the corresponding avirulence effector,AvrRppC,which is secreted by P.polysora and triggers RppC-mediated resistance.Allelic variation of AvrRppC directly determines the effectiveness of RppC-mediated resistance,indicating that monitoring of AvrRppC variants in the field can guide the rational deployment of RppC-containing hybrids in maize production.Currently,RppC is the most frequently deployed SCR resistance gene in China,and a better understanding of its mode of action is crit-ical for extending its durability. | Ce Deng April Leonard James Cahill Meng Lv Yurong Li Shawn Thatcher Xueying Li Xiaodi Zhao Wenjie Du Zheng Li Huimin Li Victor Llaca Kevin Fengler Lisa Marshall Charlotte Harris Girma Tabor Zhimin Li Zhiqiang Tian Qinghua Yang Yanhui Chen Jihua Tang Xintao Wang Junjie Hao Jianbing Yan Zhibing Lai Xiaohong Fei Weibin Song Jinsheng Lai Xuecai Zhang Guoping Shu Yibo Wang Yuxiao Chang Weiling Zhu Wei Xiong Juan Sun Bailin Li Junqiang Ding | 2022 | Molecular Plant2022，15，5： | 6 |
| 3 | Contents of soil organic carbon and nitrogen in water-stable aggregates in abandoned agricultural lands in an arid ecosystem of Northwest China显示文摘Soil organic matter content in water-stable aggregates(WSA) in the arid ecosystems(abandoned agricultural lands especially) of China is poorly understood. In this study, we examined the WSA sizes and stability, and soil organic carbon(OC) and nitrogen(N) contents in agricultural lands with abandonment ages of 0, 3, 12, 20, 30 and 40 years, respectively, in the Minqin Oasis of Northwest China. The total soil OC and N contents at depths of 0–20, 20–40 and 40–60 cm in abandoned agricultural lands were compared to those in cultivated land(the control). Agricultural land abandonment significantly(P<0.05) influenced the distribution of MWD(mean weight diameter), and OC and N contents. There were significant increases in MWD and the proportion of macroaggregates(sizes >0.25 mm) as the age of agricultural land abandonment increased. The effect of abandonment ages of agricultural lands on MWD was determined by the changes of OC and N accumulation in WSA sizes >2 mm. The total OC and N contents presented a stratification phenomenon across soil depths in this arid ecosystem. That is, both of them decreased significantly at depths of 0–20 and 40–60 cm while increased at the depth of 20–40 cm. The WSA sizes <0.053 mm had the highest soil OC and N contents(accounting for 51.41%–55.59% and 42.61%–48.94% of their total, respectively). Soil OC and N contents in microaggregates(sizes 0.053–0.25 mm) were the dominant factors that influenced the variations of total OC and N contents in abandoned agricultural lands. The results of this study suggested that agricultural land abandonment may result in the recovery of WSA stability and the shifting of soil organic matter from the silt+clay(<0.053 mm) and microaggregate fractions to the macroaggregate fractions. However, agricultural land abandonment did not increase total soil OC and N contents in the short-term. | WANG Junqiang LIU Lichao QIU Xiaoqing WEI Yujie LI Yanrong SHI Zhiguo | 2016 | Journal of Arid Land2016，8，3： | 6 |
| 4 | Low Speed Axial Compressor Stall Margin Improvement by Unsteady Plasma Actuation显示文摘This research investigates the use of single dielectric barrier discharge(SDBD) actuators for energizing the tip leakage flow to suppress rotating stall inception and extend the stable operating range of a low speed axial compressor with a single rotor.The jet induced by the plasma actuator adds momentum to the flow in the tip region and has a significant impact on the tip-gap flow.Experiments are carried out on a low speed axial compressor with a single rotor.The static pressure is measured at both the rotor inlet and outlet.The flow coefficient and pressure rise coefficient are calculated.Then the characteristic line is acquired to show the overall performance of the compressor.With unsteady plasma actuation of 18kV and 60W the compressor stability range improvement is realized at rotor speed of 1500 r/min – 2400 r/min. | LI Gang XU Yanji YANG Lingyuan DU Wei ZHU Junqiang NIE Chaoqun | 2014 | Journal of Thermal Science2014，23，2： | 3 |
| 5 | Computational Investigation of Blade slotting on a High-Load Low-Pressure Turbine Profile at various Reynolds Numbers:Part Ⅰ——Slotting Scheme's Verification显示文摘Boundary layer separation and reattachment is often an unavoidable feature of low pressure (LP) turbine,one of the main causes of this phenomenon is the high altitude low Reynolds number experienced by the modern LP turbine stage in aero-engine.Although an excellent turbine airfoil design can avoid flow separation on certain extent,but within flight envelope,LP turbine's characteristic Reynolds number may varied greatly,so it will be still under the risk of the presence of separation bubble.In this two parts paper a new concept of slotted-blade was raised to testify the gain of the blade slotting.A high aerodynamic loading LP turbine blade IET-LPTA was under investigated with different Reynolds number.Computational results reveal that the blade slotting could be a way of choice to suppress separation bubble and reduce profile loss under the condition of low Reynolds number,although its position and geometry need to be further investigated. | Qiang Du Junqiang Zhu Min Zhou Wei Li | 2011 | Journal of Thermal Science2011，20，1： | 3 |
| 6 | Computational Investigation of Blade Slotting on a High-Load Low-Pressure Turbine Profile at Various Reynolds Numbers:Part Ⅱ——Optimization of Slotting Position显示文摘The concept of using blade slotting to suppress the large boundary layer separation of high aerodynamic loading low pressure turbine profile has been developed in Part 1.Calculated results highlight the inability performance accompanied with un-proper blade slotting at high Reynolds number,blade slotting optimization seems like compulsory.Meanwhile,to further dignify the rational for use of blade slotting,slotting position and its geometry needed to be optimized.Comparison of different slotting scheme calculation results promised that blade slotting parameter like outlet angle and outlet position are the most important parameters which must be investigated to satisfy the design purpose. | Qiang Du Junqiang Zhu Min Zhou Wei Li | 2011 | Journal of Thermal Science2011，20，1： | 2 |
| 7 | Clinicopathological features of pseudomyogenic hemangioendothelioma and precision therapy based on whole exome sequencing显示文摘Dear Editor Pseudomyogenic hemangioendothelioma(PHE)is a newly recognized subtype of hemangioendothelioma characterized by the presence of fibrohistiocytic and myoid cells arranged in a fibroma-like or dermatofibroma-like pattern[1].This rare type of tumor was first named by Hornick and Fletcher[2]and categorized as the novel soft tissue tumor classification system of the World Health Organization in 2013[3].Prior to this,it was referred to as fibroma-like variant of epithelioid sarcoma(ES)and epithelioid sarcoma-like hemangioendothelioma[4]. | Junqiang Wei Zhichao Liao Gang Zhao Nazmun Nahar Chao Zhang Jia Lu Yun Yang Jilong Yang | 2020 | Cancer Communications2020，40，4： | 2 |
| 8 | Osseointegration of hollow porous titanium prostheses loaded with cancellous bone matrix in rabbits显示文摘This study aimed to observe the osseointegration of hollow porous titanium prostheses (HPTP) loaded with cancellous bone matrix (CBM) in rabbits using histological and biomechanical perspectives.Experimental samples were implanted into the lateral femoral condyles of 66 New Zealand rabbits,allocated into the following groups:non-porous prosthesis group (Group A,n=22);HPTP group (Group B,n=22);HPTP+CBM group (Group C,n=22).The rabbits were sacrificed at 3,8 and 12 weeks,postoperatively.X-ray analyses,microscopy techniques and morphological measurement software and mechanical tests were used for evaluation.At each time point,the tissues surrounding the implants were similar in all of the groups,with bony in-growth into the 2-mm round holes observed for the defects in Groups B and C.However,the internal bone formation was significantly better in Group C than in Group B at different time points (P<0.01).Biomechanically,the pull-out forces were significantly greater in Groups B and C than in Group A (P<0.01),with no difference between Groups B and C (P>0.05).These results suggest that bone can grow into the cavities of HPTP to achieve more stable locking fixation,and those osteogenic materials,such as CBM,can enhance osteogenesis to achieve better osseointegration between the implant and the host bone. | WEI JunQiang CAI Xu WANG Yan ZHANG BoXun CHEN Hua ZHANG Li ZHAO Bin WANG AiYua | 2012 | Chinese Science Bulletin2012，57，20： | 2 |
| 9 | Effects of the crystallization time on the mesoporous structure,texture, morphology and styrene oxidation performances of V-MCM-41显示文摘The new V-MCM-41 molecular sieves with good ordered hexagonal mesoporous structure and crystallinity were synthesized through in-situ hydrothermal preparation method. The effects of the crystallization time were discussed. The synthesized samples were characterized by X-ray diffraction, N2adsorption/desorption, Fourier transformed infrared and scanning electron microscopy. The different structures, textures, morphologies of V-MCM-41 obtained with different crystallization times were observed and analyzed on the basis of the characterized results. The results showed that the V-MCM-41 molecular sieve obtained at 110 °C for 48 h crystallization times was of good spherical morphology, ordered hexagonal structure, most uniform pore size distribution and high surface area compared with other samples. Meanwhile, the V-MCM-41 molecular sieve with the high skeleton Si condensation and the good crystallinity was obtained. The heteroatom could be incorporated into MCM-41 framework with increasing crystallization times, which was beneficial to improve the catalytic activity and selectivity of pure siliceous MCM-41. The V-MCM-41 showed the good catalytic selectivity in catalytic oxidation of styrene using hydrogen peroxide, and the selectivity of the benzaldehyde and phenylacetic acid reached 30.68%and 49.44%, respectively. | Junqiang Xu Qiang Zhang Fang Guo Jingping Hong Wei Chu | 2016 | Journal of Energy Chemistry2016，25，6： | 2 |
| 10 | A 320 Gb/s capacity (32 users×10 Gb/s) SPECTS O-CDMA network testbed with enhanced spectral efficiency through forward error correction显示文摘 | Hernandez V J Cong Wei Hu Junqiang | 2007 | Journal of Lightwave Technology2007，25，1： | 1 |
| 11 | Silencing glypican-3 expression induces apoptosis in human hepatocellular carcinoma cells显示文摘 | Shiyuan Liu Yumin Li Wei Chen Pengfei Zheng Tao Liu Wenting He Junqiang Zhang Xiangting Zeng | 2012 | Biochemical and Biophysical Research Communications2012，，4： | 1 |
| 12 | Synthesis and characteriza- tion of mesoporous V-MCM-41 molecular sieves with good hydro- thermal and thermal stability 显示文摘 | Xu Junqiang Chu Wei Luo Shizhong | 2006 | Journal of Molecular Catalysis A: Chemical2006，256，12： | 1 |
| 13 | Bandwidth and tenability enhan-cement of wavelength conversion by quasi-phase-matching difference frequency generation显示文摘 | Liu Wei Sun Junqiang | 2003 | Optics Communications2003，216，： | 1 |
| 14 | Synthesis and characterization of mesoporous V-MCM-41 molecular sieves with good hydrothermal and thermal stability 显示文摘 | XU Junqiang CHU Wei LUO Shizhong | 2006 | J Mol Catal A: Chem2006，256，12： | 1 |
| 15 | Multi-objective optimization-based prediction of excavation-induced tunnel displacement显示文摘This paper proposes an inverse method for improving the prediction of tunnel displacements during adjacent excavation.In this framework,staged data assimilation and parameter identification are conducted using the multi-objective particle swarm optimization algorithm.Recent monitoring data are assumed to be more informative and assigned more weights in the multi-objective optimization to improve the prediction accuracy.Then,an empirical formula is applied to correct the time effect of tunnel displacement.The Kriging method is introduced to surrogate the finite element model to reduce computational cost.The proposed framework is verified using a typical staged“excavation nearing tunnel”case.The predictions using the updated parameters are in good agreement with the measurements.The identified values of underlying soil parameters are within the typical ranges for the unloading condition.The updated time effect indicates that tunnel displacements may develop excessively in the three months after the region S1-B is excavated to the bottom.The maximum vertical tunnel displacement may increase from the currently measured 12 mm to the calculated 26 mm if the later construction is suspended long enough.Subsequent constructions need to be timely conducted to restrain the time effect and control tunnel displacements. | Yuanqin Tao Wei He Honglei Sun Yuanqiang Cai Junqiang Chen | 2022 | Underground Space2022，7，5： | 1 |
| 16 | Bandwidth and tenability enhancement of wavelength conversion by quasi-phase-matching difference frequency generation显示文摘 | Liu Wei Sun Junqiang Kurz Jonathan | 2003 | Optics Communication2003，216，： | 1 |
| 17 | AHA1 upregulates IDH1 and metabolic activity to promote growth and metastasis and predicts prognosis in osteosarcoma显示文摘Osteosarcoma(OS)is the most common primary malignant bone tumor in children and adolescents.Although activator of HSP90 ATPase activity 1(AHA1)is reported to be a potential oncogene,its role in osteosarcoma progression remains largely unclear.Since metabolism reprogramming is involved in tumorigenesis and cancer metastasis,the relationship between AHA1 and cancer metabolism is unknown.In this study,we found that AHA1 is significantly overexpressed in osteosarcoma and related to the prognosis of osteosarcoma patients.AHA1 promotes the growth and metastasis of osteosarcoma both in vitro and in vivo.Mechanistically,AHA1 upregulates the metabolic activity to meet cellular bioenergetic needs in osteosarcoma.Notably,we identifed that isocitrate dehydrogenase 1(IDH1)is a novel client protein of Hsp90 AHA1.Furthermore,the IDH1 protein level was positively correlated with AHA1 in osteosarcoma.And IDH1 overexpression could partially reverse the effect of AHA1 knockdown on cell growth and migration of osteosarcoma.Moreover,high IDH1 level was also associated with poor prognosis of osteosarcoma patients.This study demonstrates that AHA1 positively regulates IDH1 and metabolic activity to promote osteosarcoma growth and metastasis,which provides novel prognostic biomarkers and promising therapeutic targets for osteosarcoma patients. | Diwei Zheng Weihai Liu Wenlin Xie Guanyu Huang Qiwei Jiang Yang Yang Jiarong Huang Zihao Xing Mengling Yuan Mengning Wei Yao Li Junqiang Yin Jingnan Shen Zhi Shi | 2021 | Signal Transduction and Targeted Therapy2021，6，2： | 1 |
| 18 | Synthesis and characterization of mesoporous V-MCM-41 molecular sieves with good hydrothermal and thermal stability显示文摘 | Xu Junqiang Chu Wei Luo Shizhong | 2006 | Journal of Molecular Catalysis A:Chemical2006，256，12： | 1 |
| 19 | Oxidations of two-dimensional semiconductors:Fundamentals and applications显示文摘Since the discovery of graphene,two-dimensional(2D)semiconductors have been attracted intensive interest due to their unique properties.They have exhibited potential applications in next generation electronic and optoelectronic devices.However,most of the 2D semiconductor are known to suffer from the ambient oxidation which degrade the materials and therefore hinder us from the intrinsic materials’properties and the optimized performance of devices.In this review,we summarize the recent progress on both fundamentals and applications of the oxidations of 2D semiconductors.We begin with the oxidation mechanisms in black phosphorus,transition metal dichalcogenides and transition metal monochalcogenides considering the factors such as oxygen,water,and light.Then we show the commonly employed passivation techniques.In the end,the emerging applications utilizing controlled oxidations will be introduced. | Junqiang Yang Xiaochi Liu Qianli Dong Yaqi Shen Yuchuan Pan Zhongwang Wang Kui Tang Xianfu Dai Rongqi Wu Yuanyuan Jin Wei Zhou Song Liu Jian Sun | 2022 | Chinese Chemical Letters2022，33，1： | 0 |
| 20 | Chinese Compilation of Physical Activities in healthy adults aged 18-64:Categories and metabolic intensities显示文摘A Chinese Compilation of Physical Activities was compiled to estimate the energy costs of physical activities(PAs)using data on adults aged 18–64.Data were obtained from published articles and laboratory measurements.Databases,including PubMed,Embase,Scopus,Ebsco,Web of Science,Chinese National Knowledge Infrastructure,Wan Fang Data,National Science and Technology Report Service,Public Health Scientific Data were searched to collect data from inception to January 2022,on energy expenditure associated with PA in the healthy Chinese population.Two reviewers independently screened the literature and extracted,classified,and summarized data.Data were measured for 36 PAs using indirect calorimetry.Detailed descriptions of specific activities and metabolic equivalent values were provided by summarizing 241 physical activities in 13 categories.The first edition of the Chinese Compilation of PAs in Healthy Adults Aged 18–64(CCPA)was created.It provides valuable resources for people who regularly engage in physical exercise,researchers,educators,fitness professionals,and health or commercial sectors to quickly obtain various PA MET intensities.In the future,the energy expenditure of various PAs of different ages within the Chinese population can be measured based on the CCPA. | Junqiang Qiu Junchao Yang Mingyue Lu Yuyang Chen Yanping Yang Wei Cao Kun Meng Yan Chen Jun Zhang Chunyan Xu Longyan Yi Xian Guo Yang Wang Xiaolei Liu Yi Yan Hanjun Li Qin Zhuo Wenhua Zhao Lianshi Feng Barbara E.Ainsworth | 2022 | Sports Medicine and Health Science2022，4，3： | 0 |
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