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| 1 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014,5,2: | 5 |
| 2 | Current state of endohepatology: Diagnosis and treatment of portal hypertension and its complications with endoscopic ultrasound显示文摘The diagnosis and management of cirrhosis and portal hypertension(PH)with its complications including variceal hemorrhage,ascites,and hepatic encephalopathy continues to evolve.Although there are established“standards of care”in liver biopsy and measurement of PH,gastric varices remain an area without a universally accepted therapeutic approach.The concept of“Endo Hepatology”has been used to describe of the applications of endoscopic ultrasound(EUS)to these challenges.EUS-liver biopsy(EUS-LB)offers an alternative to percutaneous and transjuglar liver biopsy without compromising safety or efficacy,and with added advantages including the potential to reduce sampling error by allowing biopsies in both hepatic lobes.Furthermore,EUS-LB can be performed during the same procedure as EUS-guided portal pressure gradient(PPG)measurements,allowing for the collection of valuable diagnostic and prognostic data.EUS-guided PPG measurements provide an appealing alternative to the transjugular approach,with proposed advantages including the ability to directly measure portal vein pressure.In addition,EUS-guided treatment of gastric varices(GV)offers several possible advantages to current therapies.EUS-guided treatment of GV allows detailed assessment of the vascular anatomy,similar efficacy and safety to current therapies,and allows the evaluation of treatment effect through doppler ultrasound visualization.The appropriate selection of patients for these procedures is paramount to ensuring generation of useful clinical data and patient safety. | Sean R Rudnick Jason D Conway Mark W Russo | 2021 | World Journal of Hepatology2021,13,8: | 4 |
| 3 | Arabidopsis microRNA167 controls patterns of ARF6 and ARF8 expression, and regulates both female and male reproduction显示文摘 | Wu M F Tian Q Jason W R | 2006 | Development2006,133,: | 1 |
| 4 | Dairy tariff-quota liberalization:contrasting bilateral and most favored na-tion reform options显示文摘 | JASON H G THOMAS W H THOMAS F R | 2009 | American Journal of Agricultural Eco-nomics2009,91,3: | 1 |
| 5 | Calcium efflux is essential for bacterial survival in the eukaryotic host 显示文摘 | Jason W R Jack S Geli G | 2008 | Molecular Microbiology2008,70,2: | 1 |
| 6 | Network Dy- namics and Field Evolution : The Growth of Interorganizational Col- laboration in the Life Sciences 显示文摘 | Powell W W White D R Koput K W Jason O S | 2005 | American Journal of Sociology2005,110,4: | 1 |
| 7 | Effects of the combination treatment of raloxifene and alendronate on the biomechanical properties of vertebral bone显示文摘 | Tamim D Jason W Susan R | 2011 | J Bone Miner Res2011,26,: | 1 |
| 8 | Rib Fractures Under Anterior-posterior Dynamic Loads: Experimental and Finite Element Study显示文摘 | Li Zuoping Kindig Matthew W Kerrigan Jason R | 2010 | Journal of Biomechanics2010,43,2: | 1 |
| 9 | X-Ray Absorp-tion Fine Structure Characterization of the Local Structure ofFe in Fe-ZSM-5 显示文摘 | Sun H C Benjamin R W Jason A R | 2003 | J Phys Chem B2003,107,11: | 1 |
| 10 | Calorie restriction and resveratrol in cardiovascular health and disease 显示文摘 | Dolinsky Vernon W Dyck Jason R B | 2011 | Bioehimica et hiophysiea aeta2011,1812,11: | 1 |
| 11 | Retained surgical sponge simulating a pancreatic mass 显示文摘 | Jason R S Chisolm A Lubetsky H W | 1979 | J Natl Med Assoc1979,71,5: | 1 |
| 12 | Surface passivation of bare aluminum nanoparticles using perfluoroalkyl carboxylic acids 显示文摘 | Jason J R Andrea D W David M R | 2005 | Chem Mater2005,,17: | 1 |
| 13 | The Effect of space and parabolic flight on macrophage hematopoiesis and function显示文摘 | Armstrong Jason W Richard A Gerren R A | 1995 | Exp Cell Res1995,216,1: | 1 |
| 14 | Rib fractures under anterior-posterior dynamic loads: experimental and finite element study 显示文摘 | Li Zuo-ping Kindig Matthew W Kerrigan Jason R | 2010 | Journal of Biomechanics2010,43,2: | 1 |
| 15 | Surface passivation of bare aluminum nanoparticles using perfluoroalkyl carboxylic acids显示文摘 | Jason J R Andrea W D David R M | 2005 | Chem Mater2005,17,11: | 1 |
| 16 | Quantifying threats to imperiled species in the Unite States显示文摘 | David S W David R Jason D | | 0,,08: | 1 |
| 17 | Flexible Boron- Doped Laser- Induced Graphene Microsupercapacitors显示文摘 | Peng Z W Ye R Q Jason A M | 2015 | ACS Nano2015,9,6: | 1 |
| 18 | Symptom occurrence in persons with chronic fatigue syndrome显示文摘 | Torres-Harding S R Carrico A W | 2002 | Biol Psychol2002,59,: | 1 |
| 19 | Nutrient uptake, partition- ing, and remobilization in modern, transgenic insect-protected maize hybrids显示文摘 | Ross R B Jason W H Matias L R | 2013 | Agronomy Journal2013,105,: | 1 |
| 20 | Control of SIVmac239 is not predicted by inheritance of Mamu-B * 17- containing haplotypes 显示文摘 | Jason A W Yant L J Wiseman R W | 2007 | J Virol2007,81,: | 1 |