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| 1 | Diagnosis of hepatocellular carcinoma显示文摘Hepatocellular carcinoma (HCC) is one of the commonest cancers worldwide, particularly in parts of the developing world, and is increasing in incidence. This article reviews the current modalities employed for the diagnosis of HCC, including serum markers, radiological techniques and histological evaluation, and summarises international guidelines for the diagnostic approach to HCC. | Asmaa I Gomaa Shahid A Khan Edward LS Leen Imam Waked Simon D Taylor-Robinson | 2009 | World Journal of Gastroenterology2009，15，11： | 44 |
| 2 | 长白山区典型泥炭藓沼泽的有壳变形虫显示文摘选择长白山区哈泥、金川、圆池和赤池4个典型泥炭藓沼泽作为研究地点,在系统采样基础上调查了有壳变形虫的种类组成特征。75个样品共记录到有壳变形虫33种。这些种类均为国外研究中的常见种类,其中优势种类有苔藓鳞盖虫(Assulina muscorum)、表壳圆壳虫(Cyclopyxis arcelloidestype)、蛹壳虫/三足虫(Croythion-Trinematype)、巧茄壳虫(Hyalosphenia eleglans)、结节鳞壳虫(Euglypha tuberculatatype)、网匣壳虫(Centropyxiscassistype)、染色梨壳虫(Nebela tincta)、泥炭藓截口虫(Heleopera sphagni)。特别是凤蝶茄壳虫(H.papilio)为国内新纪录,它是泥炭藓沼泽的典型种类之一。其他研究中常见的Amphitrema flavum在本研究中未发现。 | 李鸿凯 王升忠 卜兆君 赵红艳 安芷生 Edward A D Mitchell 马云艳 | 2010 | 湿地科学2010，8，3： | 11 |
| 3 | Mechanosignaling activation of TGFβmaintains intervertebral disc homeostasis显示文摘Intervertebral disc(IVD) degeneration is the leading cause of disability with no disease-modifying treatment.IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal(NC) cells to maintain IVD homeostasis. Here we report that mechanical stress can result in excessive integrin α_vβ_6-mediated activation of transforming growth factor beta(TGFβ), decreased NC cell vacuoles, and increased matrix proteoglycan production, and results in degenerative disc disease(DDD). Knockout of TGFβ type II receptor(TβRII) or integrin α_v in the NC cells inhibited functional activity of postnatal NC cells and also resulted in DDD under mechanical loading.Administration of RGD peptide, TGFβ, and α_vβ_6-neutralizing antibodies attenuated IVD degeneration. Thus,integrin-mediated activation of TGFβ plays a critical role in mechanical signaling transduction to regulate IVD cell function and homeostasis. Manipulation of this signaling pathway may be a potential therapeutic target to modify DDD. | Qin Bian Lei Ma Amit Jain Janet L Crane Khaled Kebaish Mei Wan Zhengdong Zhang X Edward Guo Paul D Sponseller Cheryle A Seguin Lee H Riley Yongjun Wang Xu Cao | 2017 | Bone Research2017，5，1： | 9 |
| 4 | Reoperation for prosthetic aortic valve obstruction in the era of echocardiography: trends in diagnostic testing and comparison with surgical findings显示文摘 | Steven E Girard Fletcher A Miller Thomas A Orszulak Charles J Mullany Samantha Montgomery William D Edwards Henry D Tazelaar Joseph F Malouf A.Jamil Tajik | 2001 | Journal of the American College of Cardiology2001，，2： | 2 |
| 5 | Dose Reconstruction显示文摘 | Lloyd D C Edwards AA Protracted Overexposure to a 137Cs Source:Ⅰ | 1999 | Radiation Protection Dosimetry1999，81，2： | 1 |
| 6 | Analysis of stained objects in histological sections by spectral imaging and differential absorption显示文摘 | Woemer B M Edwards D A | 1999 | Journal of Histochemistry & Cytochemistry1999，47，10： | 1 |
| 7 | Measurement ofinterfacial dilational viscosity at high rates of interface expansion using the maximum bubble pressure method 1:Gas-liquid interface显示文摘 | Edwards D A Wasan D T | 1992 | Journal of Colloid and Interface Science1992，148，1： | 1 |
| 8 | A role forSalmonella fimbriae in intraperitoneal infections 显示文摘 | Edward tk A Schifferli D M Maloy S R | 2000 | Proc Natl Acad Sci USA2000，97，3： | 1 |
| 9 | The effect of cultural conditions on growth and secondary metabolism in Streptomycesth ermovilaceus显示文摘 | JAMES P D A EDWARDS C | 1988 | FEMS Microbiol Lett1988，52，： | 1 |
| 10 | The effect of cultural conditions on growth and secondary metabolism in Strepto- mycesth ermovilaceus显示文摘 | James P D A Edwards C | 1998 | FEMS Microbiol Lett1998，52，： | 1 |
| 11 | Effect of chemical amendments on ammonia volatilization from poultry litter显示文摘 | Moore P A J Daniel T C Edwards D R | 1995 | Journal of Environmental Quality1995，24，： | 1 |
| 12 | Influence of sorption on the biological utilization of two simple carbon substrates显示文摘 | JONES D L EDWARDS A C | 1998 | Soil Biology & Biochemistry1998，30，： | 1 |
| 13 | Toll-like receptor expression in murine DCsubsets:lack of TLR7 expression by CD8-DC correlates with unresponsiveness to imidazoquinolinrs显示文摘 | Edwards A D Diebold S S Slack E M | 2003 | Eur J Immunol2003，33，： | 1 |
| 14 | Measurement ofinterfacial dilational viscosity at high rates of interface expansion using the maximum bubble pressure method1:Liquid-liquid interface显示文摘 | Edwards D A Wasan D T | 1993 | Journal of Colloid and Interface Science1993，155，： | 1 |
| 15 | A three-component deformation model for image-guided surgery显示文摘 | Edwards P J Hill D L G Little J A | 1998 | Medical Image Analysis1998，2，4： | 1 |
| 16 | Hemodilution reduces early reperfusion injury in an ex vivo rabbit lung preservation model 显示文摘 | John D P Oka T Mayer E Edward A | 1994 | Ann Thorac Surg1994，57，： | 1 |
| 17 | PKI Elliptic Curve Cryptography,and Digital Signatures显示文摘 | William J C Edward P D Scott A R | 1999 | Computers and Security1999，18，： | 1 |
| 18 | The diffraction of a planar detonation wave at an abrupt area change 显示文摘 | Edwards D H Thomas G O Nettleton M A | 1979 | Journal of Fluid Mechanics1979，95，： | 1 |
| 19 | Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD显示文摘 | Lonas D A Silverman E K Edwards L D | 2009 | Eur Respir J2009，34，1： | 1 |
| 20 | Role of granule-bound starch synthase in determination of amylopectin structure and starchgranule morphology in potato显示文摘 | Fulton D Edwards A Pilling E | 2002 | J Biol Chem2002，277，10： | 1 |
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