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| 1 | Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Modulate the Anesthetic Potency of Isoflurane in Mice显示文摘The lateral hypothalamic area(LHA)plays a pivotal role in regulating consciousness transition,in which orexinergic neurons,GABAergic neurons,and melanin-concentrating hormone neurons are involved.Glutamatergic neurons have a large population in the LHA,but their anesthesia-related effect has not been explored.Here,we found that genetic ablation of LHA glutamatergic neurons shortened the induction time and prolonged the recovery time of isoflurane anesthesia in mice.In contrast,chemogenetic activation of LHA glutamatergic neurons increased the time to anesthesia and decreased the time to recovery.Optogenetic activation of LHA glutamatergic neurons during the maintenance of anesthesia reduced the burst suppression pattern of the electroencephalogram(EEG)and shifted EEG features to an arousal pattern.Photostimulation of LHA glutamatergic projections to the lateral habenula(LHb)also facilitated the emergence from anesthesia and the transition of anesthesia depth to a lighter level.Collectively,LHA glutamatergic neurons and their projections to the LHb regulate anesthetic potency and EEG features. | Shiyi Zhao Rui Li Huiming Li Sa Wang Xinxin Zhang Dan Wang Juan Guo Huihui Li Ao Li Tingting Tong Haixing Zhong Qianzi Yang Hailong Dong | 2021 | Neuroscience Bulletin2021，37，7： | 5 |
| 2 | Role of HO-1 in protec- tive effect of electro-acupuncture against endotoxin shock- induced acute lung injury in rabbits 显示文摘 | Yu JB Dong SA Luo XQ | 2013 | Exp Biol Med (Maywood)2013，238，6： | 1 |
| 3 | Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5显示文摘 | Xiao FQ Dong SA Irvin SY | | 0，，： | 1 |
| 4 | Immunogenicity of the Mycobacterium tuberculosis PPE55(Rv3347c) protein during incipient and clinical tuberculosis显示文摘 | Singh KK Dong Y Patibandla SA | 2005 | Infect Immun2005，73，8： | 1 |
| 5 | Estrogen Receptor-A in Medial Preoptic Area Contributes to Sex Difference of Mice in Response to Sevoflurane Anesthesia显示文摘A growing number of studies have identified sex differences in response to general anesthesia;however,the underlying neural mechanisms are unclear.The medial preoptic area(MPA),an important sexually dimorphic structure and a critical hub for regulating consciousness transition,is enriched with estrogen receptor alpha(ERa),particularly in neuronal clusters that participate in regulating sleep.We found that male mice were more sensitive to sevoflurane.Pharmacological inhibition of ERαin the MPA abolished the sex differences in sevoflurane anesthesia,in particular by extending the induction time and facilitating emergence in males but not in females.Suppression of ERαin vitro inhibited GABAergic and glutamatergic neurons of the MPA in males but not in females.Furthermore,ERα.knockdown in GABAergic neurons of the male MPA was sufficient to eliminate sex differences during sevoflurane anesthesia.Collectively,MPA ERαpositively regulates the activity of MPA GABAergic neurons in males but not in females,which contributes to the sexdifference of mice in sevoflurane anesthesia. | Yunyun Zhang Huiming Li Xinxin Zhang Sa Wang Dan Wang Jiajia Wang Tingting Tong Zhen Zhang Qianzi Yang Hailong Dong | 2022 | Neuroscience Bulletin2022，38，7： | 1 |
| 6 | Quick, sensitive and specific detection and evaluation of quantification of minor variants by high-throughput sequencing 显示文摘 | Leung R K Dong Z Q Sa F | 2013 | Mol Biosyst2013，10，2： | 1 |
| 7 | Characterization of an Arabidopsis mutant that is nonresponsive to inducers of systemic acquired resistance显示文摘 | Cao H Bowling SA Gordon S Dong X | | 0，，06： | 1 |
| 8 | Role of HO-1 in protective effect of electro-acupuncture against endotoxin shock-inducedacute lung injury in rabbits 显示文摘 | Yu JB Dong SA Luo XQ | 2013 | Exp Biol Med(Maywood)2013，238，6： | 1 |
| 9 | Ag-catalyzed GaSb nanowires for flexible near-infrared photodetectors显示文摘High-quality narrow bandgap semiconductors nanowires(NWs)challenge the flexible near-infrared(NIR)photodetectors in next-generation imaging,data communication,environmental monitoring,and bioimaging applications.In this work,complementary metal oxide semiconductor-compatible metal of Ag is deposited on glass as the growth catalyst for the surfactantassisted chemical vapor deposition of GaSb NWs.The uniform morphology,balance stoichiometry,high-quality crystallinity,and phase purity of as-prepared NWs are checked by scanning electron microscopy,energy dispersive X-ray spectroscopy,high-resolution transmission electron microscopy,and X-ray diffraction.The electrical properties of as-prepared NWs are studied by constructing back-gated field-effect-transistors,displaying a high I_(on)/I_(off) ratio of 10^(4) and high peak hole mobility of 400 cm^(2)/(V·s).Benefiting from the excellent electrical and mechanical flexibility properties,the as-fabricated NW flexible NIR photodetector exhibits high sensitivity and excellent photoresponse,with responsivity as high as 618 A/W and detectivity as high as 6.7×10^(10) Jones.Furthermore,there is no obvious decline in NIR photodetection behavior,even after parallel and perpendicular folding with 1200 cycles. | Zixu Sa Fengjing Liu Dong Liu Mingxu Wang Jie Zhang Yanxue Yin Zhiyong Pang Xinming Zhuang Peng Wang Zaixing Yang | 2022 | Journal of Semiconductors2022，43，11： | 1 |
| 10 | A fatal case of simultaneous,very late thrombosis involving three drug- eluting stents in three coronary arteries显示文摘 | Yong SA Cho JH Dong HK | 2008 | Korean Circ J2008，38，： | 1 |
| 11 | Role of HO-1 in protective effect of electro-acupuncture against endotoxin shock-induced acute lung injury in rabbits 显示文摘 | Yu JB Dong SA Luo XQ | 2013 | Exp Biol Med (Maywood)2013，238，6： | 1 |
| 12 | A randomized phase II study of weekly docetaxel/cisplatin versus weekly docetaxel/oxaliplatin as first-line therapy for patients with advanced gastric cancer显示文摘 | Young Saing Kim Sun Jin Sym Se Hoon Park Inkeun Park Junshik Hong Hee Kyung Ahn Jinny Park Eun Kyung Cho Woon Ki Lee Min Chung Jae Hoon Lee Dong Bok Shin | 2014 | Cancer Chemotherapy and Pharmacology2014，，1： | 1 |
| 13 | Mitomycin C plus S-1 as second-line therapy in patients with advanced gastric cancer: a noncomparative phase II study显示文摘 | Se Hoon Park Young Saing Kim Junshik Hong Jinny Park Eunmi Nam Eun Kyung Cho Dong Bok Shin Jae Hoon Lee Woon Kee Lee Min Chung | 2008 | Anti-Cancer Drugs2008，，3： | 1 |
| 14 | Effect of electroacupuncture atZusanli(ST36) and Sanyinjiao(SP6) acupoints on adrenocorticalfunction in etomidate anesthesia patients显示文摘 | Yu JB Dong SA Gong LR | 2014 | Med Sci Monit2014，20，： | 1 |
| 15 | Lentivirus - mediated gene transfer induces long - term transgene expression of BMP - 2 in vitro and new bone formation in vivo 显示文摘 | Osamu S Dong SA Sam PKK | 2005 | Mol Ther2005，3，： | 1 |
| 16 | Phase II trial of weekly docetaxel and gemcitabine for previously untreated, advanced non-small cell lung cancer显示文摘 | Se Hoon Park Junshik Hong Young Saing Kim Yujin Kim Sun Young Kyung Chang Hyeok An Sang Pyo Lee Jeong Woong Park Sung Hwan Jeong Jinny Park Eun Kyung Cho Dong Bok Shin Jae Hoon Lee | 2008 | Lung Cancer2008，，1： | 1 |
| 17 | Percutaneous vertebro- plasty compared with conservative treatment in patients with chronic painful osteoporotic spinal fractures 显示文摘 | Dong C Zhi-Quan A Sa S | 2014 | Journal of Clinical Neuroscience2014，21，3： | 1 |
| 18 | A Case of Primary Adenosquamous Carcinoma of the Liver Presented with Liver Abscess显示文摘 | Oh Sa ng Kwon Hong Sik Le e Dong Wook Ko h | 2001 | The Korean Journal of Internal Medicine2001，16，2： | 1 |
| 19 | Role of HO-1 in protective ef- fect of electro-acupuncture against endotoxin shock-induced acute lung injury in rabbits 显示文摘 | Yu JB Dong SA Luo XQ | 2013 | Exp Biol Med (Maywood)2013，238，6： | 1 |
| 20 | 5-Aza-2'-deoxycytidine (decitabine) can relieve p21 WAF1 repression in human acute leukemia by a mechanism involving release of histone deacetylase 1 (HADC1) without requiring promoter demethylation显示文摘 | Scott SA Dong WF Ichinohasama R | 2006 | Leukemia Reseach2006，30，1： | 1 |
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