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| 1 | Astronomical tuning and magnetostratigraphy of Neogene biogenic reefs in Xisha Islands, South China Sea显示文摘Biogenic reefs are one of two major depositional types in the South China Sea, and are constructed by coral, algae and bryozoa. The West Pacific is a major area of biogenic reef development and plays a critical role in the global carbon cycle. However, the lack of geochronological studies in previous works inhibits our understanding of their contributions. Herein, we conduct a cyclostratigraphic and magnetostratigraphic study on Neogene biogenic reefs using the XK–1 core that was drilled at the Shidao Island,Xisha(Paracel) Islands. The main findings of this study are:(1) the establishment of reliable magentostratigraphy for Ledong, Huangliu, Meishan and Sanya Formations;(2) the magnetic susceptibility variation can be inferred as growth index and tuned to the 405–ka long eccentricity cycle;(3) the astronomical geochronology suggests that the bottom ages for Ledong, Yinggehai, Huangliu, Meishan,and Sanya Formations are 2.2 Ma, 5.7 Ma, 10.4 Ma, 16.6 Ma, and 24.3 Ma, respectively; and (4) Earth's eccentricity and obliquity played predominant roles in biogenic reef establishment on orbital to tectonic timescales. Thus, the reported geochronology offers an opportunity to test the contributions of various factors and hypothesize their roles in the global carbon cycle in future. | Liang Yi Zhimin Jian Xinyu Liu Youhua Zhu Daojun Zhang Zhenfeng Wang Chenglong Deng | 2018 | Science Bulletin2018，63，9： | 12 |
| 2 | A heavy mineral viewpoint on sediment provenance and environment in the Qiongdongnan Basin显示文摘Based on heavy mineral data in core samples from eleven drillings, supplemented by paleontological, element geochemical and seismic data, the evolution of sediment provenance and environment in the Qiongdongnan Basin(QDNB) was analysed. The results show that the basement in the QDNB was predominantly composed of terrigenous sediments. Since the Oligocene the QDNB has gradually undergone transgressions and evolution processes in sedimentary environment from terrestrial-marine transitional to littoral-neritic, neritic, and bathyal roughly. The water depth showed a gradually increasing trend and was generally greater in the southern region than that in the northern region in the same time. With changes in sedimentary environment, provenances of the strata(from the Yacheng Formation to the Yinggehai Formation) showed principal characteristics of multisources, evolving from autochthonous source, short source to distant source step by step. During the Early Oligocene, the sediments were mainly proximal basaltic pyroclastic source and adjacent terrigenous clastic source, afterwards were becoming distant terrigenous clastic sources, including Hainan Island on the north,Yongle Uplift on the south, Shenhu Uplift on the northeast, the Red River System on the northwest and Indochina Peninsula on the southwest, or even a wider region. The Hainan Island provenance began to develop during the Early Oligocene and has become a main provenance in the QDNB since the Middle Miocene. The provenances from Yongle Uplift and Shenhu Uplift most developed from the Late Oligocene to the Early Miocene and gradually subsided during the Middle Miocene. During the Late Miocene, as a main source of sediments filled in the central canyon, the Red River System provenance added to the QDNB massively, whose impact terminated at the end of the Pliocene. The western Yinggehai Basin(YGHB) provenance derived from Indochina Peninsula had developed from the Pliocene on to the Pleistocene. In addition, the material contribution of marine authigenous source to the basin(especially to the southern region) could not be ignored. | LIU Xiaofeng ZHANG Daojun ZHAI Shikui LIU Xinyu CHEN Hongyan LUO Wei LI Na XIU Chun | 2015 | Acta Oceanologica Sinica2015，34，4： | 10 |
| 3 | New insights on the origin of the basement of the Xisha Uplift,South China Sea显示文摘The study of basement geochronology provides crucial insights into the tectonic evolution of oceans. However, early studies on the basement of the Xisha Uplift were constrained by limited geophysical and seismic data; Xiyong1 was the only commercial borehole drilled during the 1970 s because of the huge thickness of overlying Cenozoic strata on the continental margin. Utilizing two newly-acquired basement samples from borehole XK1, we present petrological analysis and zircon uranium(U)-lead(Pb) isotope dating data in this paper that enhance our understanding of the formation and tectonic features of the Xisha Uplift basement. Results indicate that this basement is composed of Late Jurassic amphibole plagiogneisses that have an average zircon 206 Pb/238 U age of 152.9±1.7 Ma. However, the youngest age of these rocks, 137±1 Ma, also suggests that metamorphism termination within the Xisha basement occurred by the Early Cretaceous. These metamorphic rocks have adamellites underneath them which were formed by magmatic intrusions during the late stage of the Early Cretaceous(107.8±3.6 Ma). Thus, in contrast to the Precambrian age(bulk rubidium(Rb)-strontium(Sr) analysis, 627 Ma) suggested by previous work on the nearby Xiyong1 borehole, zircons from XK1 are likely the product of Late Mesozoic igneous activity. Late Jurassic-Early Cretaceous regional metamorphism and granitic intrusions are not confined to Xisha; rocks have also been documented from areas including the Pearl River Mouth Basin and the Nansha Islands(Spratly Islands) and thus are likely closely related to large-scale and long-lasting subduction of the paleo-Pacific plate underneath the continental margins of East Asia, perhaps the result of closure of the Meso-Tethys in the South China Sea(SCS). Controversies remain as to whether, or not, the SCS region developed initially on a uniform Precambrian-aged metamorphic crystalline basement. It is clear, however, that by this time both Mesozoic compressive subduction and Cenozoic rifting and extension had significantly modified the original basement of the SCS region. | ZHU WeiLin XIE XiNong WANG ZhenFeng ZHANG DaoJun ZHANG ChengLi CAO LiCheng SHAO Lei | 2017 | Science China Earth Sciences2017，60，12： | 10 |
| 4 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 5 | Geology and hydrocarbon accumulations in the deepwater of the northwestern South China Sea——with focus on natural gas显示文摘The deepwater of the northwestern South China Sea is located in the central to southern parts of the Qiongdongnan Basin(QDN Basin),which is a key site for hydrocarbon exploration in recent years.In this study,the authors did a comprehensive analysis of gravity-magnetic data,extensive 3D seismic survey,cores and cuttings,paleontology and geochemical indexes,proposed the mechanism of natural gas origin,identified different oil and gas systems,and established the model of hydrocarbon accumulations in the deep-water region.Our basin tectonic simulation indicates that the evolution of QDN Basin was controlled by multiple-phased tectonic movements,such as Indochina-Eurasian Plate collision,Tibetan Uplift,Red River faulting and the expansion of the South China Sea which is characterized by Paleogene rifting,Neogene depression,and Eocene intensive faulting and lacustrine deposits.The drilling results show that this region is dominated by marineterrestrial transitional and neritic-bathyal facies from the early Oligocene.The Yacheng Formation of the early Oligocene is rich in organic matter and a main gas-source rock.According to the geological-geochemical data from the latest drilling wells,Lingshui,Baodao,Changchang Sags have good hydrocarbon-generating potentials,where two plays from the Paleogene and Neogene reservoirs were developed.Those reservoirs occur in central canyon structural-lithologic trap zone,Changchang marginal trap zone and southern fault terrace of Baodao Sag.Among them,the central canyon trap zone has a great potential for exploration because the various reservoirforming elements are well developed,i.e.,good coal-measure source rocks,sufficient reservoirs from the Neogene turbidity sandstone and submarine fan,faults connecting source rock and reservoirs,effective vertical migration,late stage aggregation and favorable structural–lithological composite trapping.These study results provide an important scientific basis for hydrocarbon exploration in this region,evidenced by the recent discovery of the significant commercial LS-A gas field in the central canyon of the Lingshui Sag. | WANG Zhenfeng SUN Zhipeng ZHANG Daojun ZHU Jitian LI Xushen HUANG Baojia GUO Minggang JIANG Rufeng | 2015 | Acta Oceanologica Sinica2015，34，10： | 9 |
| 6 | Characterising the nature, evolution and origin of detachment fault in central depression belt, Qiongdongnan Basin of South China Sea: evidence from seismic reflection data显示文摘Using regional geological, newly acquired 2D and 3D seismic, drilling and well log data, especially 2D long cable seismic profiles, the structure and stratigraphy in the deep-water area of Qiongdongnan Basin are interpreted. The geometry of No.2 fault system is also re-defined, which is an important fault in the central depression belt of the deep-water area in the Qiongdongnan Basin by employing the quantitative analysis techniques of fault activity and backstripping. Furthermore, the dynamical evolution of the No.2 fault system and its controls on the central depression belt are analyzed. This study indicates that the Qiongdongnan Basin was strongly influenced by the NW-trending tensile stress field during the Late Eocene. At this time, No.2 fault system initiated and was characterized by several discontinuous fault segments, which controlled a series small NE-trending fault basins. During the Oligocene, the regional extensional stress field changed from NW-SE to SN with the oceanic spreading of South China Sea, the early small faults started to grow along their strikes, eventually connected and merged as the listric shape of the No.2 fault system as observed today. No.2 fault detaches along the crustal Moho surface in the deep domain of the seismic profiles as a large-scale detachment fault. A large-scale rollover anticline formed in hanging wall of the detachment fault. There are a series of small fault basins in both limbs of the rollover anticline, showing that the early small basins were involved into fold deformation of the rollover anticline. Structurally, from west to east, the central depression belt is characterized by alternatively arranged graben and half-graben. The central depression belt of the Qiongdongnan Basin lies at the extension zone of the tip of the V-shaped northwestern ocean sub-basin of the South China Sea, its activity period is the same as the development period of the northwestern ocean sub-basin, furthermore the emplacement and eruption of magma that originated from the mantle below the Moho surface occurred at the region between Songnan-Baodao and Changchang sags, from east to west with the early-stage spreading of the South China Sea. Therefore, this study not only helps in depicting the structural features and evolution of the deep-water basin in the Qiongdongnan Basin, but also provides the geological and structural evidence for establishing a unified model of continental margin extension and oceanic spreading. | REN Jianye ZHANG Daojun TONG Dianjun HUANG Anmin WANG Yahui LEI Chao ZUO Qianmei ZHAO Yanghui HE Weijun YANG Linlong | 2014 | Acta Oceanologica Sinica2014，33，12： | 8 |
| 7 | Evaluation of efficacy and safety of gandouling plus sodium dimercaptosulphonate in treatment of patients with neurological Wilson's disease from China显示文摘OBJECTIVE: To evaluate the efficacy and safety of gandouling plus sodium dimercaptosulphonate(DMPS) on neurological Wilson's disease(WD) in patients.METHODS: We retrospectively evaluated the clinical records of 125 WD patients with neurological syndromes who were treated with gandouling plus sodium DMPS or DMPS used alone. All patients had a history of neurological deterioration during their diseases courses. The clinical efficacies, adverse reactions, and results of the various hematological and biochemical investigations were recorded for statistical analysis.RESULTS: 92.30%(60 patients) of the WD patients treated with the combined therapy experienced an improved or stable neurological condition paral-leled by a significantly improved GAS score. Meanwhile, the WBC and PLT counts stabilized, liver function and renal function were improved or remained stable. The combined therapy also obviously promoted the 24-h urinary copper excretion. In particular, only 30.76% of the WD patients experienced mild adverse reactions, including neurological deterioration in 5 patients(7.69%), hepatic worsening in 1 subject(1.89%), which was less frequently than those in the control group treated with DMPS only.CONCLUSION: Our findings indicate that the safety and efficacy of gandou-ling plus DMPS is superior to those of DMPS used alone in the WD patients with neurological symptoms. | Zhang Jing Xie Daojun Guo Yanbing Li Yajun Li Liangyong Han Hui Zhang Juan Chen Huaizhen Wang Meixia | 2018 | Journal of Traditional Chinese Medicine2018，38，5： | 7 |
| 8 | Novel synthesis of fly-ash-derived Cu-loaded SAPO-34 catalysts and their use in selective catalytic reduction of NO with NH3显示文摘A combined acid–alkali hydrothermal method was used to prepare fly ash–derived SAPO-34 molecular sieves from a thermal power plant in Inner Mongolia(China).The specific surface area of the prepared fly-ash-derived SAPO-34 molecular sieves was 579 m^2 g^-1,the total pore volume was about 0.27 cm^3 g^-1,and the pore size was 0.56 nm;the molar ratios of Al2O3:P2O5:SiO2 were 1:0.86:0.45.Cu/SAPO-34 catalysts were prepared by impregnation of low-cost fly-ash-derived SAPO-34 molecular sieves as a support and tested in selective catalytic reduction with NH3(NH3-SCR).Powder X-ray diffraction(XRD),N2 adsorption–desorption,X-ray photoelectron spectroscopy(XPS),H2 temperatureprogrammed reduction(H2-TPR),NH3 temperature-programmed desorption(NH3-TPD),electron paramagnetic resonance(EPR),nuclear magnetic resonance(NMR),X-ray fluorescence analysis(XRF)and scanning electron microscopy(SEM)were used for catalyst characterization and investigation of the relationships between the catalyst structure and the catalytic activity.The actual silica:alumina ratio of the molecular sieves did not increase with increasing Cu loading,indicating that increasing the Cu loading does not change the original structure of the SAPO-34 molecular sieves.The XRF and NMR results showed that replacement by Cu results in more Si islands.The molecular sieve acidity decreased because of the increased number of Si islands.The NH3-TPD results showed that for the Cu/SAPO-34 catalysts there was a low correlation between the low-temperature activity and the amount of acidic sites.SCR activity is closely related to the location of Cu.The 4.47 Cu/SAPO-34 catalyst has the highest isolated Cu2+showed the highest NH3-SCR activities(>90%)at 250–350℃.This work opens up new avenues for recycling fly ash formed in coal-fired power plants(reducing environmental pollution)and developing low-cost SCR catalysts for NOx pollution control. | Ge Li Baodong Wang Qi Sun Wayne Qiang Xu Ziran Ma Hongyan Wang Daojun Zhang Jiali Zhou | 2019 | Green Energy & Environment2019，4，4： | 6 |
| 9 | Evolution of deepwater sedimentary environments and its implication for hydrocarbon exploration in Qiongdongnan Basin, northwestern South China Sea显示文摘Over the past several years, a number of hydrocarbon reservoirs have been discovered in the deepwater area of Qiongdongnan Basin, northwestern South China Sea. These oil/gas fields demonstrate that the evolution of the deepwater sedimentary environment are controlling the formation and distribution of large-scale clastic reservoirs. Integration between seismic and borehole data were necessary to best clarify the distribution and quality of these deepwater reservoirs. Geochemical and paleobiological evidence from discrete samples was also applied to document specific information regarding the sedimentary environment. Results show that the Qiongdongnan Basin has existed as a thriving marine environment since Oligocene, when several rifting depressions developed throughout the entire Qiongdongnan Basin. Triggered by the faults activities, several distinct provenances supplied the coarse sediments, transporting and depositing them in deep parts of the rifting depressions. A fan delta system then formed nearby the source in the deeper area of these rifting depressions. The sedimentary environment of Qiongdongnan gradiationally became deepwater since early Miocene.Consequently, abundances of sediments were transported from Hainan Island and Southern Uplift, and then sunk into the basin center. The submarine fans revealed by many boreholes in this area verified them as good reservoir. Because the area reached its lowest sea level at late Miocene and the Southern Uplift subsidenced under sea level, not providing any sediment, so that the carbonate mesa and biorhythms characteristic of this area also developed during this period. In the west part of Qiongdongnan Basin, sediments transported from Vietnam increased in response to the Tibetan Uplift. Consequently, a central canyon developed along the center of Qiongdongnan Basin, which has been confirmed by several boreholes as a favorable hydrocarbon reservoir. The clarification of the deepwater sedimentary environment's evolution is potentially highly beneficial to future hydrocarbon exploration in the deepwater area of Qiongdongnan Basin. | WANG Zhenfeng JIANG Tao ZHANG Daojun WANG Yahui ZUO Qianmei HE Weijun | 2015 | Acta Oceanologica Sinica2015，34，4： | 6 |
| 10 | Difference in full-filled time and its controlling factors in the Central Canyon of the Qiongdongnan Basin显示文摘Based on the interpretation of high resolution 2D/3D seismic data,sedimentary filling characteristics and fullfilled time of the Central Canyon in different segments in the Qiongdongnan Basin of northwestern South China Sea have been studied.The research results indicate that the initial formation age of the Central Canyon is traced back to 11.6 Ma(T40),at which the canyon began to develop due to the scouring of turbidity currents from west to east.During the period of 11.6–8.2 Ma(T40–T31),strong downcutting by gravity flow occurred,which led to the formation of the canyon.The canyon fillings began to form since 8.2 Ma(T31) and were dominated by turbidite deposits,which constituted of lateral migration and vertical superposition of turbidity channels during the time of8.2–5.5 Ma.The interbeds of turbidity currents deposits and mass transport deposits(MTDs) were developed in the period of 5.5–3.8 Ma(T30–T28).After then,the canyon fillings were primarily made up of large scale MTDs,interrupted by small scale turbidity channels and thin pelagic mudstones.The Central Canyon can be divided into three types according to the main controlling factors,geomorphology-controlled,fault-controlled and intrusionmodified canyons.Among them,the geomorphology-controlled canyon is developed at the Ledong,Lingshui,Songnan and western Baodao Depressions,situated in a confined basin center between the northern slope and the South Uplift Belt along the Central Depression Belt.The fault-controlled canyon is developed mainly along the deep-seated faults in the Changchang Depression and eastern Baodao Depression.Intrusion-modified canyon is only occurred in the Songnan Low Uplift,which is still mainly controlled by geomorphology,the intrusion just modified seabed morphology.The full-filled time of the Central Canyon differs from west to east,displaying a tendency of being successively late eastward.The geomorphology-controlled canyon was completely filled before3.8 Ma(T28),but that in intrusion-modified canyon was delayed to 2.4 Ma(T27) because of the uplifted southern canyon wall.To the Changchang Depression,the complete filling time was successively late eastward,and the canyon in eastern Changchang Depression is still not fully filled up to today.Difference in full-filled time in the Central Canyon is mainly governed by multiple sediment supplies and regional tectonic activities.Due to sufficient supply of turbidity currents and MTDs from west and north respectively,western segment of the Central Canyon is entirely filled up earlier.Owing to slower sediment supply rate,together with differential subsidence by deep-seated faults,the full-filled time of the canyon is put off eastwards gradually. | SHANG Zhilei XIE Xinong LI Xushen ZHANG Daojun HE Yunlong YANG Xing CUI Mingzhe | 2015 | Acta Oceanologica Sinica2015，34，10： | 5 |
| 11 | Abrogation of Hn RNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8^(+) T cell-mediated ferroptosis in castration-resistant prostate cancer显示文摘Owing to incurable castration-resistant prostate cancer(CRPC)ultimately developing after treating with androgen deprivation therapy(ADT),it is vital to devise new therapeutic strategies to treat CRPC.Treatments that target programmed cell death protein 1(PD-1)and programmed death ligand-1(PD-L1)have been approved for human cancers with clinical benefit.However,many patients,especially prostate cancer,fail to respond to anti-PD-1/PD-L1 treatment,so it is an urgent need to seek a support strategy for improving the traditional PD-1/PD-L1 targeting immunotherapy.In the present study,analyzing the data from our prostate cancer tissue microarray,we found that PD-L1 expression was positively correlated with the expression of heterogeneous nuclear ribonucleoprotein L(Hn RNP L).Hence,we further investigated the potential role of Hn RNP L on the PD-L1 expression,the sensitivity of cancer cells to T-cell killing and the synergistic effect with anti-PD-1 therapy in CRPC.Indeed,Hn RNP L knockdown effectively decreased PD-L1 expression and recovered the sensitivity of cancer cells to T-cell killing in vitro and in vivo,on the contrary,Hn RNP L overexpression led to the opposite effect in CRPC cells.In addition,consistent with the previous study,we revealed that ferroptosis played a critical role in T-cell-induced cancer cell death,and Hn RNP L promoted the cancer immune escape partly through targeting YY1/PD-L1 axis and inhibiting ferroptosis in CRPC cells.Furthermore,Hn RNP L knockdown enhanced antitumor immunity by recruiting infiltrating CD8^(+)T cells and synergized with anti-PD-1 therapy in CRPC tumors.This study provided biological evidence that Hn RNP L knockdown might be a novel therapeutic agent in PD-L1/PD-1 blockade strategy that enhanced anti-tumor immune response in CRPC. | Xumin Zhou Libin Zou Hangyu Liao Junqi Luo Taowei Yang Jun Wu Wenbin Chen Kaihui Wu Shengren Cen Daojun Lv Fangpeng Shu Yu Yang Chun Li Bingkun Li Xiangming Mao | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 4 |
| 12 | Effects of kanglaite capsules combined with transcatheter arterial chemoembolization (TACE) on patients with mid or late-stage primary hepatocellular carcinoma (HCC)显示文摘观察囊与 transcatheter 相结合的 kanglaite (KLT ) 的临床的效果的目的动脉的 chemoembolization (不作声) 在与中间或迟了阶段的主要肝细胞癌(HCC ) 对待病人。65 个盒子随机被划分成 2 个组,的方法在联合组的 32 个病人接受了 KLT 囊 + 的治疗不作声,在控制组的 33 个病人被对待与独自不作声。客观反应率(RR ) ,浆液高山哈 fetoprotein (法新社) ,外部血 T 淋巴细胞亚群(T-LS ) ,生命(QOL ) 的质量,前进(TTP ) 的时间和不利反应在 2 之间被遵守并且比较组。客观反应评估的结果和浆液高山哈 fetoprotein 层次没有在二个组之间的有效差量(P >
0.05 ) 。联合组是优异的在生命(QOL ) 的质量控制组,前进(TTP ) 的时间,外部血 T 淋巴细胞亚群(CD3+ , CD4+ , CD4+∖CD8 比率) 并且肝不利反应,与有效差量(P <
0.05 ) 。结论 KLT 囊与结合了不作声是到对待的一个有效方法失去了外科的治疗的机会的主要肝细胞癌(HCC ) 病人。 | Daojun Li Xinhua Xu Dan Bao Feng Xue Delan Dai | 2009 | The Chinese-German Journal of Clinical Oncology2009，8，2： | 4 |
| 13 | Improving DNA damage repair ability of E. coli to UV-radiosensitivity by DNA-mediated gene transfer of low energy ion beam显示文摘Using calcium chloride method of transfer gene as control, a new technique of transferring gene by low energy ion beam has been applied to the study of improving DMA damage repair ability of E. coli to UV-radiosensitivity. The genome DMA pieces of Deinococcus radio-durans, as 'foreign' genetic materials, were introduced into the UV-radiosensitive strains of E. | SONG Daojun and YU XunCenter of Ion Beam Bioengineering, Institute of Plasma Physics , Chinese Academy of Sciences , Hefei 230031, China College of Life Science , University of Science and Technology of China , Hefei 230026, China | 1999 | Chinese Science Bulletin1999，44，19： | 4 |
| 14 | Gas accumulation conditions and key technologies for exploration & development of Sulige gasfield显示文摘Up to now,the Sulige area in Ordos Basin has the favorable exploration area of 55×10^(3) km^(2),the total reserve of natural gas of nearly 6×10^(12) m^(3) and the proven reserve(including basic proven reserve)of 4.77×10^(12) m^(3),where the annual production of natural gas reaches 23×10^(9) m^(3),and the Sulige gasfield is the largest onshore natural gas field in China.The pay zone of the Sulige gasfield mainly is Member 8 of Shihezi Formation and Member 1 of Shanxi Formation of Permian which belong to the typical tight sandstone gas reservoir.The coal measure strata in Carboniferous Benxi Formation,Permian Taiyuan Formation and Shanxi Formation provide abundant gas sources for the Gulige gas reservoirs.An open-flow sedimentary model of lacustrine delta is developed,the gentle bottom,sand supply from multisource,strong hydrodynamic force and multi-period superposition control the distribution of largearea reservoir sand body.Lithology of the reservoir is the sandstone of the fluvial-delta facies,the physical property is poor and the heterogeneity is strong,the average porosity ranges from 4%to 12%and the average permeability varies from 0.01 to 1 mD.The gas reservoir is characterized by wide hydrocarbon generation,pervasive hydrocarbon charging,short-range migration and massive accumulation.The pressure coefficient of the gas reservoir ranges from 0.62 to 0.90,indicating the low-pressure gas reservoir,and the single-well yield is low.Full digital seismic technique in the desert area,nonlongitudinal seismic technique in the loess plateau,accurate logging evaluation technique,tight sand reservoir stimulation technology and horizontal well development technology are key technologies for exploration and development of Sulige gasfield. | Jinhua Fu Liyong Fan Xinshe Liu Daojun Huang | 2018 | Petroleum Research2018，3，2： | 3 |
| 15 | CFD simulation on the generation of turbidites in deepwater areas: a case study of turbidity current processes in Qiongdongnan Basin, northern South China Sea显示文摘Turbidity currents represent a major agent for sediment transport in lakes, seas and oceans. In particular, they formulate the most significant clastic accumulations in the deep sea, which become many of the world's most important hydrocarbon reservoirs. Several boreholes in the Qiongdongnan Basin, the northwestern South China Sea, have recently revealed turbidity current deposits as significant hydrocarbon reservoirs. However, there are some arguments for the potential provenances. To solve this problem, it is essential to delineate their sedimentary processes as well as to evaluate their qualities as reservoir. Numerical simulations have been developed rapidly over the last several years, offering insights into turbidity current behaviors, as geologically significant turbidity currents are difficult to directly investigate due to their large scale and often destructive nature. Combined with the interpretation of the turbidity system based on highresolution 3D seismic data, the paleotophography is acquired via a back-stripping seismic profile integrated with a borehole, i.e., Well A, in the western Qiongdongnan Basin; then a numerical model is built on the basis of this back-stripped profile. After defining the various turbidity current initial boundary conditions, including grain size, velocity and sediment concentration, the structures and behaviors of turbidity currents are investigated via numerical simulation software ANSYS FLUENT. Finally, the simulated turbidity deposits are compared with the interpreted sedimentary bodies based on 3D seismic data and the potential provenances of the revealed turbidites by Well A are discussed in details. The simulation results indicate that a sedimentary body develops far away from its source with an average grain size of 0.1 mm, i.e., sand-size sediment. Taking into account the location and orientation of the simulated seismic line, the consistence between normal forward simulation results and the revealed cores in Well A indicates that the turbidites should have been transported from Vietnam instead of Hainan Island. This interpretation has also been verified by the planar maps of sedimentary systems based on integration of boreholes and seismic data. The identification of the turbidity provenance will benefit the evaluation of extensively distributed submarine fans for hydrocarbon exploration in the deepwater areas. | JIANG Tao ZHANG Yingzhao TANG Sulin ZHANG Daojun ZUO Qianmei LIN Weiren WANG Yahui SUN Hui WANG Bo | 2014 | Acta Oceanologica Sinica2014，33，12： | 3 |
| 16 | A Deletable and Modifiable Blockchain Scheme Based on Record Verification Trees and the Multisignature Mechanism显示文摘As one of the most valuable technologies,blockchains have received extensive attention from researchers and industry circles and are widely applied in various scenarios.However,data on a blockchain cannot be deleted.As a result,it is impossible to clean invalid and sensitive data and correct erroneous data.This,to a certain extent,hinders the application of blockchains in supply chains and Internet of Things.To address this problem,this study presents a deletable and modifiable blockchain scheme(DMBlockChain)based on record verification trees(RVTrees)and the multisignature scheme.(1)In this scheme,an RVTree structure is designed and added to the block structure.The RVTree can not only ensure that a record is true and valid but,owing to its unique binary structure,also verify whether modification and deletion requests are valid.(2)In DMBlockChain,the multisignature mechanism is also introduced.This mechanism requires the stakeholders’signatures for each modification or deletion request and thus ensures that a record will not be modified arbitrarily.A user’s request is deemed valid only if it is dually verified by the RVTree and the multisignature mechanism.The analysis finds that DMBlockChain can provide a secure and valid means for modifying and deleting records in a block while ensuring the integrity of the block and that DMBlockChain can effectively save space in some scenarios that require frequent records modification. | Daojun Han Jinyu Chen Lei Zhang Yatian Shen Yihua Gao Xueheng Wang | 2021 | Computer Modeling in Engineering & Sciences2021，，7： | 3 |
| 17 | Poly(α-L-lysine)-based nanomaterials for versatile biomedical applications:Current advances and perspectives显示文摘Poly(α-L-lysine)(PLL)is a class of water-soluble,cationic biopolymer composed ofα-L-lysine structural units.The previous decade witnessed tremendous progress in the synthesis and biomedical applications of PLL and its composites.PLL-based polymers and copolymers,till date,have been extensively explored in the contexts such as antibacterial agents,gene/drug/protein delivery systems,bio-sensing,bio-imaging,and tissue engineering.This review aims to summarize the recent advances in PLL-based nanomaterials in these biomedical fields over the last decade.The review first describes the synthesis of PLL and its derivatives,followed by the main text of their recent biomedical applications and translational studies.Finally,the challenges and perspectives of PLL-based nanomaterials in biomedical fields are addressed. | Maochao Zheng Miao Pan Wancong Zhang Huanchang Lin Shenlang Wu Chao Lu Shijie Tang Daojun Liu Jianfeng Cai | 2021 | Bioactive Materials2021，6，7： | 2 |
| 18 | Mode for reducing wind curtailment based on battery transportation显示文摘Renewable energy sources, such as wind and solar, face several obstacles, including curtailment, where the generated energy exceeds local demand and production must be reduced because of limited transmission capacity.Simultaneously, consumer demand for large-capacity batteries is expanding given the recent rapid development of electric vehicles(EVs) and plug-in hybrid EVs. A batterycharging mode, in which discharged batteries are transported from battery exchange stations in high-load areas to wind farms, is proposed to alleviate curtailment. In this study, batteries store otherwise curtailed energy and smooth the wind power output simultaneously. The structure of the battery-charging device is discussed, and the concept of a battery-charging container is proposed. The control principle of the battery-charging management unit is presented with a simulation model constructed in the PSCAD/EMTDC environment. A case study is simulated,and the feasibility of the mode is analyzed considering the levelized cost and energy losses. Simulation results show that this mode is a feasible solution to alleviating wind curtailment and providing fresh impetus for developing EV battery exchanges. | Zhanlong ZHANG Daojun MEI Han JIANG Guohua LIU Hongpeng HE Yue CHEN | 2018 | Journal of Modern Power Systems and Clean Energy2018，6，6： | 2 |
| 19 | MAPT as a predisposing gene for sporadic amyotrophic lateral sclerosis in the Chinese Han population显示文摘A previous study of European Caucasian patients with sporadic amyotrophic lateral sclerosis demonstrated that a polymorphism in the microtubule-associated protein Tau(MAPT) gene was significantly associated with sporadic amyotrophic lateral sclerosis pathogenesis.Here,we tested this association in 107 sporadic amyotrophic lateral sclerosis patients and 100 healthy controls from the Chinese Han population.We screened the mutation-susceptible regions of MAPT–the 3′ and 5′ untranslated regions as well as introns 9,10,11,and 12–by direct sequencing,and identified 33 genetic variations.Two of these,105788 A>G in intron 9 and 123972 T>A in intron 11,were not present in the control group.The age of onset in patients with the 105788 A>G and/or the 123972 T>A variant was younger than that in patients without either genetic variation.Moreover,the patients with a genetic variation were more prone to bulbar palsy and breathing difficulties than those with the wild-type genotype.This led to a shorter survival period in patients with a MAPT genetic variant.Our study suggests that the MAPT gene is a potential risk gene for sporadic amyotrophic lateral sclerosis in the Chinese Han population. | Pu Fang Wenyuan Xu Chengsi Wu Min Zhu Xiaobing Li Daojun Hong | 2013 | Neural Regeneration Research2013，8，33： | 2 |
| 20 | A Comprehensive Review of Security-constrained Unit Commitment显示文摘Security-constrained unit commitment(SCUC)has been extensively studied as a key decision-making tool to determine optimal power generation schedules in the operation of electricity market.With the development of emerging power grids,fruitful research results on SCUC have been obtained.Therefore,it is essential to review current work and propose future directions for SCUC to meet the needs of developing power systems.In this paper,the basic mathematical model of the standard SCUC is summarized,and the characteristics and application scopes of common solution algorithms are presented.Customized models focusing on diverse mathematical properties are then categorized and the corresponding solving methodologies are discussed.Finally,research trends in the field are prospected based on a summary of the state-of-the-art and latest studies.It is hoped that this paper can be a useful reference to support theoretical research and practical applications of SCUC in the future. | Nan Yang Zhenqiang Dong Lei Wu Lei Zhang Xun Shen Daojun Chen Binxin Zhu Yikui Liu | 2022 | Journal of Modern Power Systems and Clean Energy2022，10，3： | 2 |
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