|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The Lp-saturation of mixed exponential type integral operator显示文摘 | Chen Wenzhong Chui Zhenlu | 1993 | J Math Res & Exposition1993,13,1: | 2 |
| 2 | E3 ligase FBXW7 aggravates TMPD-induced systemic lupus erythematosus by promoting cell apoptosis显示文摘Systemic lupus erythematosus(SLE)is a systemic autoimmune disease,and the pathogenesis of SLE has not been fully elucidated.The E3 ubiquitin ligase FBXW7 has been well characterized in cancer as a tumor suppressor that can promote the ubiquitination and subsequent degradation of various oncoproteins;however,the potential role of FBXW7 in autoimmune diseases is unclear.In the present study,we identified that FBXW7 is a crucial exacerbating factor for SLE development and progression in a mouse model induced by 2,6,10,14-tetramethylpentadecane(TMPD).Myeloid cell-specific FBXW7-deficient(Lysm+FBXW7f/f)C57BL/6 mice showed decreased immune complex accumulation,glomerulonephritis,glomerular mesangial cell proliferation,and basemembrane thickness in the kidney.Lysm+FBXW7f/f mice produced fewer anti-Sm/RNP and anti-ANA autoantibodies and showed a decreased MHC II expression in B cells.In Lysm+FBXW7f/f mice,we observed that cell apoptosis was reduced and that fewer CD11b+Ly6Chi inflammatory monocytes were recruited to the peritoneal cavity.Consistently,diffuse pulmonary hemorrhage(DPH)was also decreased in Lysm+FBXW7f/f mice.Mechanistically,we clarified that FBXW7 promoted TMPD-induced cell apoptosis by catalyzing MCL1 degradation through K48-linked ubiquitination.Our work revealed that FBXW7 expression in myeloid cells played a crucial role in TMPD-induced SLE progression in mice,which may provide novel ideas and theoretical support for understanding the pathogenesis of SLE. | Zhenlu Chong Chunjing Bao Jia He Tianxiao Chen Lijia Zhong Gaopeng Li Huanle Li Lutong Fang Yinjing Song Guoxiang Fu Xuyan Yang Lihua Lai Yang Liu Qingqing Wang | 2018 | Cellular & Molecular Immunology2018,15,12: | 2 |
| 3 | The Lp-saturation of mixed exponential type integral operator显示文摘 | Chen Wenzhong Chui Zhenlu | 1993 | J Math Res&Exposition1993,13,1: | 1 |
| 4 | Vapor phase condensation of methyl acetate with formaldehyde to preparing methyl acrylate over cesium supported SBA-15 catalyst显示文摘 | Jianbiao Yan Chunlei Zhang Chunli Ning Yong Tang Yi Zhang Lili Chen Shuang Gao Zhenlu Wang Wenxiang Zhang | 2014 | Journal of Industrial and Engineering Chemistry2014,,: | 1 |
| 5 | Iridium-Catalyzed Enantioselective C(sp^3)-H Borylation of Cyclobutanes显示文摘of main observation and conclusion We herein report the first example of iridium-catalyzed enantioselective C(sp^3)-H borylation of cyclobutanes using benzoxazoline as the directing group.The combination of a chiral bidentate boryl ligand and an iridium precursor has found to effectively catalyze C(sp)-H borylation to afford a variety of cyclobutylboronates with good to excellent enantioselectivities.We also demonstrate the synthetic utility of the current method by converting the stereogenic C—B bond to other functionalities. | Xiang Chen Lili Chen Hongliang Zhao Qian Gao Zhenlu Shen Senmiao Xu | 2020 | Chinese Journal of Chemistry2020,38,12: | 1 |
| 6 | Porous 2D CuO nanosheets for efficient triethylamine detection at low temperature显示文摘The freshness of seafood can be judged by detecting the concentration of triethylamine(TEA). In this work, 2D Cu O porous nanosheets(Cu O PNs) were prepared by a graphene oxide template method and their particle sizes were regulated by changing the calcination temperature. Their structure, morphology and gas sensing performances were investigated by various characterization methods. The response(Rg/Ra) of the gas sensor based on Cu O PNs calcined at 700oC was as high as 440-100 ppm TEA at the operating temperature of 40 ℃. The detection limit was as low as 0.25 ppm. In addition, the gas sensor has good selectivity and stability. The excellent TEA sensitivity is mainly resulted from the appropriate particle size and loose porous framework. This work not only paves the way to explore the novel low temperature TEA gas sensors, but also provides deep insight on improving the structure and properties of gas sensitive materials by controlling the calcination temperature. | Feng Wang Haoran Zhong Zhenlu Chen Ding Wang Zhuangchai Lai Yonghui Deng Xianying Wang | 2023 | Chinese Chemical Letters2023,34,2: | 0 |
| 7 | 概率的类型 inLp 空格的操作员的 Asymptotic 行为 | Chen Wenzhong (1) (2) Cui Zhenlu (1) (2) | 1994 | Applied Mathematics(A Journal of Chinese Universities)1994,9,3: | 0 |
| 8 | Surface reconstruction and structural transformation of twodimensional Ni-Fe MOFs for oxygen evolution in seawater media显示文摘As a four-electron transfer reaction,oxygen evolution reaction(OER)is limited by large overpotential and slow kinetics.Here,we in-situ synthesized two-dimensional(2D)Ni-Fe metal-organic framework nanosheets on nickel foam(NixFe-TPA/NF,TPA=terephthalic acid)for oxygen evolution in alkaline and alkaline seawater electrolytes.In 1 M KOH,Ni3Fe-TPA/NF shows a low overpotential(η10)of 189 mV at 10 mA·cm^(-2) and an ultra-low overpotential of only 260 mV at 500 mA·cm^(-2).In alkaline seawater,Ni3Fe-TPA/NF still provides impressive OER performance,with anη10 of 265 mV.In-situ Raman characterization results show that the phase transition occurs during the OER,and Ni3FeOOH with more oxygen vacancies is in-situ formed,reducing the OER energy barrier.Density functional theory(DFT)reveals that the synergy between Ni and Fe reduces the energy barrier and accelerates the rate-determining step.In addition,the ultra-thin 2D sheet structure and the close combination of Ni3FeOOH and highly conductive NF support ensure the high catalytic OER activity.Therefore,the surface reconstruction and structural modification strategy can be used to design and prepare high-performance OER electrocatalysts for energy-related applications. | Liyuan Xiao Xue Bai Jingyi Han Tianmi Tang Siyu Chen Hui Qi Changmin Hou Fuquan Bai Zhenlu Wang Jingqi Guan | 2024 | Nano Research2024,17,4: | 0 |
| 9 | Preparation and formaldehyde sensitive properties of N-GQDs/SnO2 nanocomposite显示文摘Graphene quantum dots(GQDs)have both the properties of graphene and semiconductor quantum dots,and exhibit stronger quantum confinement effect and boundary effect than graphene.In addition,the band gap of GQDs will transform to non-zero from 0 eV of graphene by surface functionalization,which can be dispersed in common solvents and compounded with solid materials.In this work,the SnO2 nanosheets were prepared by hydrothermal method.As the sensitizer,nitrogen-doped graphene quantum dots(N-GQDs)were prepared and composited with SnO2 nanosheets.Sensing performance of pristine SnO2 and N-GQDs/SnO2 were investigated with HCHO as the target gas.The response(Ra/Rg)of0.1%N-GQDs/SnO2 was 256 for 100 ppm HCHO at 60℃,which was about 2.2 times higher than pristine SnO2 nanosheet.In addition,the material also had excellent selectivity and low operation temperature.The high sensitivity of N-GQDs/SnO2 was attributed to the increase of active sites on materials surface and the electrical regulation of N-GQDs.This research is helpful to develop new HCHO gas sensor and expand the application field of GQDs. | Zhenlu Chen Ding Wang Xianying Wang Junhe Yang | 2020 | Chinese Chemical Letters2020,31,8: | 0 |