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| 1 | Effect of Reclamation Time and Land Use on Soil Properties in Changjiang River Estuary,China显示文摘The objective of this study is to analyze soil physical and chemical properties,soil comprehensive functions and impact factors after different years of reclamation.Based on the survey data taken from 216 soil sampling points in the Fengxian Reclamation Area of the Changjiang (Yangtze) River Estuary,China in April 2009 and remotely sensed TM data in 2006,while by virtue of multivariate analysis of variance (MANOVA),geo-statistical analysis (GA),prin-cipal component analysis (PCA) and canonical correspondence analysis (CCA),it was concluded that:1) With the in-crease in reclamation time,soil moisture,soil salinity,soil electric conductivity and soil particle size tended to decline,yet soil organic matter tended to increase.Soil available phosphorous tended to increase in the early reclamation period,yet it tended to decline after about 49 years of reclamation.Soil nitrate nitrogen,soil ammonia nitrogen and pH changed slightly in different reclamation years.Soil physical and chemical properties reached a steady state after about 30 years of reclamation.2) According to the results of PCA analysis,the weighted value (0.97 in total) that represents soil nutrient factors (soil nitrate nitrogen,soil organic matter,soil available phosphorous,soil ammonia nitrogen,pH and soil particle size) were higher than the weighted value (0.48 in total) of soil limiting factors (soil salinity,soil elec-tric conductivity and soil moisture).The higher the F value is,the better the soil quality is.3) Different land use types play different roles in the soil function maturity process,with farmlands providing the best contribution.4) Soil physi-cal and chemical properties in the reclamation area were mainly influenced by reclamation time,and then by land use types.The correlation (0.1905) of the composite index of soil function (F) with reclamation time was greater than that with land use types (-0.1161). | SUN Yongguang LI Xiuzhen ülo MANDER HE Yanlong JIA Yue MA Zhigang GUO Wenyong XIN Zaijun | 2011 | Chinese Geographical Science2011，21，4： | 17 |
| 2 | Rocky Desertification Risk Zone Delineation in Karst Plateau Area:A Case Study in Puding County,Guizhou Province显示文摘Karst rocky desertification is a geo-ecological problem in Southwest China.The rocky desertification risk zone delineation could be used as a guide for the regional and hierarchical rocky desertification management and prevention.We chose the middle and lower reaches of the Houzhai underground basin on the karst plateau in Puding County, Guizhou Province, China as the study area and selected land use type, elevation, slope, aspect, lithology and settlement buffer as the main driving factors of the rocky desertification.The potential risk of rocky desertification was quantified with the factor-weights union method and statistical analysis method.Five grades of rocky desertification risk were delineated based on Geographic Information System.The extremely low, low, moderate, high and extremely high rocky desertification risk zones accounted for 5.01%, 44.17%, 33.92%, 15.59% and 1.30%, respectively.As a whole, the rocky desertification risk level was moderate because the area of low and moderate rocky desertification risk zones occupied 78.09% of the study area.However, more than half of the area(about 50.81%) was predicted to have moderate rocky desertification risk and above, indicating that the study area was subject to rocky desertification.Rocky desertification risk was higher in the southeast and lower in the northwest of the study area.Distinct differences in the distribution of rocky desertification risk zones corresponding to different factors have been found. | ZHANG Panpan HU Yuanman XIAO Duning LI Xiuzhen YIN Jie HE Hong S | 2010 | Chinese Geographical Science2010，20，1： | 15 |
| 3 | Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes显示文摘 | Qiaozhen Liu Rui Yang Xiuzhen Huang Hui Zhang Lingjuan He Libo Zhang Xueying Tian Yu Nie Shengshou Hu Yan Yan Li Zhang Zengyong Qiao Qing-Dong Wang Kathy O Lui Bin Zhou | 2016 | Cell Research2016，26，1： | 12 |
| 4 | Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium显示文摘 | Hui Zhang Xiuzhen Huang Kuo Liu Juan Tang Lingjuan He Wenjuan pu Qiaozhen Liu Yan Li Xueying Tian Yue Wang Libo Zhang Ying Yu Hongyan Wang Ronggui Hu Fengchao Wang Ting Chen Qing-Dong Wang Zengyong Qiao Li Zhang Kathy O Lui Bin Zhou | 2017 | Cell Research2017，27，9： | 6 |
| 5 | A Landscape Pattern Analysis Method Based on Boundaries and Nodes:A Case Study in Upper Minjiang River,China显示文摘Traditionally,patch-based analysis at the landscape scale fragmentation has been used in the study of landscape ecology while the study of boundary and node has not been considered as much detail until recently.This study investigated the possibility of applying boundary-and node-based methods in landscape pattern analysis to the upper reaches of the Minjiang River in the southwestern China.Boundary-based and node-based landscape indices were selected to be used in analyzing changes in landscape patterns,and the results were compared with analysis using traditional pattern indices.We compared the responses of patch-area-based,boundary-length-based and node-number-based indices,and concluded that boundary-based and node-based indices are more sensitive to disturbance than patch-based indices with various patterns,and node-based indices are even more sensitive than boundary-based ones.Thus,the results suggest that boundary-based and node-based pattern analysis methods provide helpful supplementary information to traditional patch-based pattern analysis methods.The results about pattern dynamics of landscapes in the upper reaches of the Minjiang River based on boundaries and nodes showed that with human disturbance,the dominance of forest landscape was weakened by other landscape types;thus the landscape pattern of the study area became more homogeneous and the boundary network became more complex.These changes further augmented disturbance interfaces in the landscape and increased the possibilities of further landscape fragmentation. | WEN Qingchun LI Xiuzhen HE Hongshi HU Yuanman CHEN Xin CHANG Yu WANG Wei BU Rencang | 2014 | Chinese Geographical Science2014，24，1： | 3 |
| 6 | Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries显示文摘冠的动脉把血流动带到心肌肉。理解冠的动脉的发展程序提供卓见进冠的动脉疾病的治疗。多重来源被描述了为包括 proepicardium,湾穴 venosus (SV ) ,和心内膜贡献冠的动脉。然而,冠的容器的发展起源仍然在强烈学习下面。我们为学习冠的开发生产了一个新基因工具,一只 AplnCreER 老鼠在开发冠的容器明确地衬里 recombinase,它表示可诱导的 Cre。冠的开发和 AplnCreER 命运跟踪的预定正式就职的定量分析证明 subepicardial endothelial 房间(EC ) 的子孙两个都入侵紧缩的心肌层形成冠的动脉并且在表面上留下生产静脉。我们发现这些 subepicardial EC 是 intramyocardial 的主要来源在发展中的心的冠的容器。在 vitro 将生物的活组织移植于培养基中培养,试金显示这些 subepicardial EC 的多数从 SV 和中庭的心内膜,然而并非从室的心内膜产生。Apln 积极的房间的同种细胞的分析显示单个 subepicardial EC 同等地作出贡献到冠的动脉和静脉。一起,这些数据建议 subepicardial EC 是 intramyocardial 的主要来源在室的冠的动脉墙,和那冠的动脉和静脉在发展中的心有普通起源。 | Xueying Tian Tianyuan Hu Hui Zhang Lingjuan He Xiuzhen Huang Qiaozhen Liu Wei Yu Liang He Zhongzhou Yang Zhen Zhang Tao P Zhong Xiao Yang Zhen Yang Yan Yan Antonio Baldini Yunfu Sun Jie Lu Robert J Schwartz Sylvia M Evans Adriana C Gittenberger-de Groot Kristy Red-Horse Bin Zhou | 2013 | Cell Research2013，23，9： | 3 |
| 7 | Embryonic senescent cells re-enter cell cycle and contribute to tissues after birth显示文摘 | Yi Li Huan Zhao Xiuzhen Huang Juan Tang Shaohua Zhang Yan Li Xiuxiu Liu Lingjuan He Zhengyu Ju Kathy O. Lui Bin-Zhou | 2018 | Cell Research2018，28，7： | 2 |
| 8 | Impact Factors on Distribution and Characteristics of Natural Plant Community in Reclamation Zones of Changjiang River Estuary显示文摘To identify impact factors on the distribution and characters of natural plants community in reclamation area, with survey data from 67 plant quadrats in July 2009, soil properties data from 216 sampling points in April 2009, and TM (30 m) data in 2006, the composition and characteristics of natural plants community in different time of the Fengxian area in the Changjiang (Yangtze) River estuary were analyzed with two-way indicator species analysis (TWINSPAN), multivariate analysis of variance (MANOVA), detrended canonical correspondence analysis (DCCA) and canonical correspondence analysis (CCA). The results show that: 1) The plant communities in the reclaimed area are mainly mesophytes and helophytic-mesophytic transitional communities, showing a gradient distribution trend with the change in reclamation years. Species richness (MA), species diversity (H) and above-ground biomass also increase with the increase of reclamation years. Nevertheless, they appear to decline slightly in the middle and late reclamation period (> 30 years). 2) With the rise in land use levels, the changes in species richness and species diversity tend to increase at first and then decrease; species dominance (D), however, tends to decline; and above-ground biomass increases slightly. 3) The distribution of the plant community is mainly influenced by the following factors: land use levels (R = 0.55, p < 0.05), soil moisture (R = 0.53, p < 0.05), soil salinity (R = 0.43, p < 0.05) and reclamation time (R = 0.40, p < 0.05). | SUN Yongguang LI Xiuzhen HE Yanlong JIA Yue MA Zhigang GUO Wenyong XIN Zaijun | 2012 | Chinese Geographical Science2012，22，2： | 2 |
| 9 | Global- ization, institutional change, and industrial location : eco- nomic transition and industrial concentration in China 显示文摘 | Canfei He Yehua Dennis Wei and Xiuzhen Xie | 2008 | Regional Studies2008，42，7： | 1 |
| 10 | Impact Analysis of Green Procurement Policy for Forest Products in France and Its Reference显示文摘In order to combat illegal logging and associated trade and promote sustainable forest management, major developed countries, including France, have implemented green procurement policy for forest products. This paper described the background of why France implements green procurement policy for forest products, analyzed the basic content of the policy, and made a comprehensive assessment of the impact of green procurement policy on suppliers, processors, eco-environment and competitiveness of forest products. Finally, with the experiences from French implementation of the green procurement policy for forest products, the paper put forward policy recommendations for China to implement green procurement policy for forest products. | Wang Xiuzhen Chen Jie He Youjun Zhou Dalin | 2011 | Chinese Forestry Science and Technology2011，10，3： | 1 |
| 11 | Globalization, Institutional Change, and Industrial Location: Economic Transition and Industrial Concentration in China显示文摘 | Canfei He Yehua Dennis Wei Xiuzhen Xie | 2008 | Regional Studies2008，，7： | 1 |
| 12 | Evaluating the effectiveness of neutral landscape models to represent a real landscape 显示文摘 | LI Xiuzhen HE Hongshi WANG Xugao | 2004 | Lands Urban Plans2004，69，： | 1 |
| 13 | An Intronic Variant of CHD7 Identified in Autism Patients Interferes with Neuronal Differentiation and Development显示文摘Genetic composition plays critical roles in the pathogenesis of autism spectrum disorder(ASD).Especially,inherited and de novo intronic variants are often seen in patients with ASD.However,the biological significance of intronic variants is difficult to address.Here,among a Chinese ASD cohort,we identified a recurrent inherited intronic variant in the CHD7 gene,which is specifically enriched in East Asian populations.CHD7 has been implicated in numerous developmental disorders including CHARGE syndrome and ASD.To investigate whether the ASD-associated CHD7 intronic variant affects neural development,we established human embryonic stem cells carrying this variant using CRISPR/Cas9 methods and found that the level of CHD7 mRNA significantly decreased compared to control.Upon differentiation towards the forebrain neuronal lineage,we found that neural cells carrying the CHD7 intronic variant exhibited developmental delay and maturity defects.Importantly,we found that TBR1,a gene also implicated in ASD,was significantly increased in neurons carrying the CHD7 intronic variant,suggesting the intrinsic relevance among ASD genes.Furthermore,the morphological defects found in neurons carrying CHD7 intronic mutations were rescued by knocking down TBR1,indicating that TBR1 may be responsible for the defects in CHD7-related disorders.Finally,the CHD7 intronic variant generated three abnormal forms of transcripts through alternative splicing,which all exhibited loss-of-function in functional assays.Our study provides crucial evidence supporting the notion that the intronic variant of CHD7 is potentially an autism susceptibility site,shedding new light on identifying the functions of intronic variants in genetic studies of autism. | Ran Zhang Hui He Bo Yuan Ziyan Wu Xiuzhen Wang Yasong Du Yuejun Chen Zilong Qiu | 2021 | Neuroscience Bulletin2021，37，8： | 1 |
| 14 | Verifiable multi-secret sharing based on LFSR sequences显示文摘 | He Chunqiang Liao Xiaofeng Cheng Xiuzhen | 2012 | Theoretical Computer Science2012，445，1： | 1 |
| 15 | Division of labor in rhizomatous species: Comparative performance of native and invasive species in the tidal marshes of the Yangtze River estuary, China显示文摘 | HE Yanlong LI Xiuzhen GUO Wenyong | 2012 | Journal of Experimental Marine Biology and Ecology2012，，： | 1 |
| 16 | Tree Planting:How Fast Can It Accelerate Post-fire Forest Restoration?——A Case Study in Northern Da Hinggan Mountains,China显示文摘In 1987,a catastrophic fire burned over 1330000 ha in the densely forested area of the Da Hinggan Mountains in the northeastern China.After the fire,intensive management including burned trunk harvesting and coniferous tree planting had been conducted to accelerate forest restoration.To study the long term effect of these activities on forest recovery,we used a simulation modeling approach to study long-term(300 years) forest dynamics under current planting and natural regeneration scenarios.Results indicate that under tree planting scenario in the severely burned area,the dominant species Dahurian larch(Larix gmelinii) can reach pre-fire level(60% of the area) within 20 years and the maximum abundance can reach nearly 90% within 100 years.While under natural regeneration scenario,it needs about 250 years to reach its pre-fire level.From the perspective of timber production,tree planting can bring twice as much timber volume as that under natural regeneration within 300 years,which is the average longevity of L.gmelinii.It needs about 70 years to reach the timber volume of pre-fire level under the planting scenario,whereas it requires at least 250 years to reach the timber volume of pre-fire level under natural regeneration scenario.Another dominant species Asian White birch(Betula platyphylla) responded negatively to the planting of coniferous species.In general,tree planting of coniferous species after fire can greatly accelerate forest restoration in terms of species abundance and target timber volume,with desirable ecological and economic returns. | LI Xiuzhen HE Hong S WANG Xugao XIE Fuju HU Yuanman LI Yuehui | 2010 | Chinese Geographical Science2010，20，6： | 1 |
| 17 | Globalization, Iinstitutional Change and Industrial Location : Economic Transaction and Industrial Concentration in China 显示文摘 | He Canfei Wei Yehua Xie Xiuzhen | 2008 | Regional Study2008，42，7： | 1 |
| 18 | Depth of edge influence of the agricultural-forest landscape boundary, Southwestern China显示文摘 | Liguang Li Xingyuan He Xiuzhen Li Qingchun Wen Hong S. He | | 0，，： | 1 |
| 19 | Globalization, Institutional Change, and Industrial Location: Economic Transition and Industrial Concentration in China显示文摘 | Canfei He Yehua Dennis Wei Xiuzhen Xie | 2008 | Regional Studies2008，，7： | 1 |
| 20 | Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway显示文摘Primary hepatic carcinoma is a common malignant tumor.The classic molecular targeted drug sorafenib is costly and is only effective for some patients.Therefore,it is of great clinical significance to search for new molecular targeted drugs.Eupalinolide B(EB)from Eupatorium lindleyanum DC.is used to treat chronic tracheitis in clinical practice.However,the role of EB in hepatic carcinoma is unknown.In this study,we first measure the effect of EB on tumor growth in a xenograft model and PDX model.The cell proliferation and migration are also detected in human hepatocarcinoma cell lines(SMMC-7721 and HCCLM3).Then,we investigate cell cycle,cell apoptosis,cell necrosis,cell autophagy,and ferroptosis by flow cytometry,western blot analysis and electron microscopy.The results demonstrate that EB exerts anti-proliferative activity in hepatic carcinoma by blocking cell cycle arrest at S phase and inducing ferroptosis mediated by endoplasmic reticulum(ER)stress,as well as HO-1 activation.When HO-1 is inhibited,EB-induced cell death and ER protein expression are rescued.The migration-related mechanism consists of activation of the ROS-ER-JNK signaling pathway and is not connected to ferroptosis.In summary,we first discover that EB inhibits cell proliferation and migration in hepatic carcinoma,and thus EB is a promising anti-tumor compound that can be used for hepatic carcinoma. | Yonghui Zhang Haoyang Zhang Jinage Mu Meiyue Han Zhihao Cao Feng Dong Tingting Wang Lian Pan Wujing Luo Jiaxin Li Huan Liu Lishan Jin Wenxuan Ding Yong Wei Xuesong Deng Dan Liu Xiuzhen He Yi Pang Xiao Mu Zhongjun Wu Dilong Chen | 2022 | Acta Biochimica et Biophysica Sinica2022，54，7： | 1 |
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