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| 1 | Clinical trial with traditional Chinese medicine intervention ''tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'' for chronic hepatitis B-associated liver failure显示文摘AIM:To study the clinical efficacy of traditional Chinese medicine(TCM)intervention'tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'('TTK')for treating liver failure due to chronic hepatitis B.METHODS:We designed the study as a randomized controlled clinical trial.Registration number of Chinese Clinical Trial Registry is Chi CTR-TRC-12002961.A total of 144 patients with liver failure due to infection with chronic hepatitis B virus were enrolled in this randomized controlled clinical study.Participants were randomly assigned to the following three groups:(1)a modern medicine control group(MMC group,36patients);(2)a'tonifying qi and detoxification'('TQD')group(72 patients);and(3)a'tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'('TTK')group(36patients).Patients in the MMC group received general internal medicine treatment;patients in the'TQD'group were given a TCM formula'tonifying qi and detoxification'and general internal medicine treatment;patients in the'TTK'group were given a TCM formula of'TTK'and general internal medicine treatment.All participants were treated for 8 wk and then followed at 48 wk following their final treatment.The primaryefficacy end point was the patient fatality rate in each group.Measurements of various virological and biochemical indicators served as secondary endpoints.The one-way analysis of variance and the t-test were used to compare patient outcomes in the different treatment groups.RESULTS:At the 48-wk post-treatment time point,the patient fatality rates in the MMC,'TQD',and'TTK'groups were 51.61%,35.38%,and 16.67%,respectively,and the differences between groups were statistically significant(P<0.05).However,there were no significant differences in the levels of hepatitis B virus DNA or prothrombin activity among the three groups(P>0.05).Patients in the'TTK'group had significantly higher levels of serum total bilirubin compared to MMC subjects(339.40μmol/L±270.09μmol/L vs 176.13μmol/L±185.70μmol/L,P=0.014).Serum albumin levels were significantly increased in both the'TQD'group and'TTK'group as compared with the MMC group(31.30 g/L±4.77g/L,30.72 g/L±2.89 g/L vs 28.57 g/L±4.56 g/L,P<0.05).There were no significant differences in levels of alanine transaminase among the three groups(P>0.05).Safety data showed that there was one case of stomachache in the'TQD'group and one case of gastrointestinal side effect in the'TTK'group.CONCLUSION:Treatment with'TTK'improved the survival rates of patients with liver failure due to chronic hepatitis B.Additionally,liver tissue was regenerated and liver function was restored. | Han-Min Li Zhi-Hua Ye Jun Zhang Xiang Gao Yan-Ming Chen Xin Yao Jian-Xun Gu Lei Zhan Yang Ji Jian-Liang Xu Ying-He Zeng Fan Yang Lin Xiao Guo-Guang Sheng Wei Xin Qi Long Qing-Jing Zhu Zhao-Hong Shi Lian-Guo Ruan Jia-Yao Yang Chang-Chun Li Hong-Bin Wu Sheng-Duo Chen Xin-La Luo | 2014 | World Journal of Gastroenterology2014，20，48： | 20 |
| 2 | Three dimensional velocity structure and accurate earthquake location in Changning–Gongxian area of southeast Sichuan显示文摘In order to understand the crustal structure and tectonic background of the Changning–Gongxiang area, southeastern Sichuan Province, where a series of moderate-to-strong earthquakes occurred in recent years, we utilized the seismic phase data both from a local dense array and from the regional seismic networks;we used the tomoDD program to invert for the high-resolution three-dimensional velocity structure within the depth range of 0–10 km and for accurate hypocentral locations in this area. We analyzed the seismogenic structures for the events of Xingwen M5.7 in 2018 and Gongxian M5.3 and Changning M6.0 in 2019. The results show that:(1) widespread lateral inhomogeneity exists in the velocity structure of the study area, and the location of the velocity anomaly is largely consistent with known structures. In the range of distinguishable depth, the inhomogeneity decreases with increasing depth, and the velocity structure anomalies in some areas are continuous in depth;(2) earthquakes occurred in clusters, showing the characteristics of zonal folding trends in the NW-SE and NE-SW directions;the focal depth in the area is generally shallow in both the sedimentary cap and the crystalline basement. The seismogenic structures of small earthquake clusters are different in size and occurrence in different sections, and the clusters occurred mostly in regions with high P-or S-wave velocities;(3) synthesis of a variety of data suggests that the seismogenic structures of the Xingwen M5.7 and Changning M6.0 earthquakes are associated with slip faults that trend NW-SE in, respectively, the south wing and the axis of the Changning–Shuanghe anticline, while that of the Gongxian M5.3 earthquake is associated with thrust faults that trend N-S in the Jianwu syncline region. The dynamic sources of the three earthquakes are all from the SE pushing of the Qinghai–Tibet block on the Sichuan basin;(4) the risk of future strong earthquakes in this area must be reevaluated in light of the facts(a)that in recent years, moderate-to-strong earthquake swarms have occurred frequently in southeast Sichuan;(b) that the complex structural area exhibits the easy-to-trigger characteristic, and(c) that the small-scale faults in this area are characterized by the phenomenon of stress 'lock and release'. | Feng Long ZhiWei Zhang YuPing Qi MingJian Liang Xiang Ruan WeiWei Wu GuoMao Jiang LongQuan Zhou | 2020 | Earth and Planetary Physics2020，4，2： | 13 |
| 3 | Fermentation-enabled wellness foods:A fresh perspective显示文摘Fermented foods represent an important segment of current food markets,especially traditional or ethnic food markets.The demand for efficient utilization of agrowastes,together with advancements in fermentation technologies(microbial-and enzyme-based processing),are stimulating rapid growth and innovation in the fermented food sector.In addition,the health-promoting benefits of fermented foods are attracting increasingly attention.The microorganisms contained in many common fermented foods can serve as“microfactories”to generate nutrients and bioactives with specific nutritional and health functionalities.Herein,recent research relating to the manufacture of fermented foods are critically reviewed,placing emphasis on the potential health benefits of fermentation-enabled wellness foods.The importance of the correct selection of microorganisms and raw materials and the need for precise control of fermentation processes are explored.Major knowledge gaps and obstacles to fermented food production and market penetration are discussed.The importance of integrating multidisciplinary knowledge,communicating with consumers,establishing regulatory frameworks specifically for fermentation-enabled wellness foods and functional fermented foods,are highlighted. | Huan Xiang Dongxiao Sun-Waterhouse Geoffrey I.N.Waterhouse Chun Cui Zheng Ruan | 2019 | Food Science and Human Wellness2019，8，3： | 12 |
| 4 | An efficient and fast polarity optimization approach for mixed polarity Reed-Muller logic circuits显示文摘尽管基因算法广泛地在混合极性芦苇思考(MPRM ) 逻辑电路的极性优化被使用了,很少研究考虑了极性变换顺序。以便改进 MPRM 逻辑电路的极性优化的效率,我们就极性变换顺序而言建议一条有效、快的极性优化途径(FPOA ) 。第一,在 FPOA 后面的主要想法是那等评估的极性集合的最好的极性变换顺序被使用建议混合基因算法(HGA ) 获得;第二,每在极性集合的极性根据 HGA 获得的最好的极性变换顺序被变换。我们的建议 FPOA 在 C 被实现,比较分析为 MCNC 基准电路被介绍了。试验性的结果证明为有更多的变量的电路, FPOA 在与极性变换顺序和改进极性优化与启发式的技术接近疏忽的传统的极性优化途径相比改进 MPRM 逻辑电路的极性优化的效率是高度有效的。 | Zhenxue HE Limin XIAO Fei GU Tongsheng XIA Shubin SU Zhisheng HUO Rong ZHANG Longbing ZHANG Li RUAN Xiang WANG | 2017 | Frontiers of Computer Science2017，11，4： | 6 |
| 5 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 6 | Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease显示文摘Accumulating evidence suggests that C-type lectin-like receptor-2(CLEC-2)plays an important role in atherothrombosis.In this case-control study,we investigated the association between CLEC-2 and incidence of coronary artery disease(CAD).A total of 216 patients,including 14 cases of stable angina pectoris(SAP,non-ACS)and 202 cases of acute coronary syndrome(ACS),and 89 non-CAD control subjects were enrolled.Plasma levels of soluble CLEC-2(sCLEC-2)were measured using the enzyme-linked immunosorbent assay(ELISA).Compared with the control group(65.69(55.36–143.22)pg/mL),the plasma levels of sCLEC-2 were significantly increased in patients with CAD(133.67(88.76–220.09)pg/mL)and ACS(134.16(88.88–225.81)pg/mL).The multivariate adjusted odds ratios(95%confidence interval)of CAD reached 2.01(1.52–2.66)(Ptrend<0.001)for each 1-quartile increase in sCLEC-2.Restricted cubic splines showed a positive dose-response association between sCLEC2 and CAD incidence(Plinearity<0.001).The addition of sCLEC-2 to conventional risk factors improved the C statistic(0.821 vs.0.761,P=0.004)and reclassification ability(net reclassification improvement:57.45%,P<0.001;integrated discrimination improvement:8.27%,P<0.001)for CAD.In conclusion,high plasma sCLEC-2 is independently associated with CAD risk,and the prognostic value of sCLEC-2 may be evaluated in future prospective studies. | Min Fei Li Xiang Xichen Chai Jingchun Jin Tao You Yiming Zhao Changgeng Ruan Yiwen Hao Li Zhu | 2020 | Frontiers of Medicine2020，14，1： | 5 |
| 7 | Molecular characterization of transformation and halogenation of natural organic matter during the UV/chlorine AOP using FT-ICR mass spectrometry显示文摘UV/chlorine process,as an emerging advanced oxidation process(AOP),was effective for removing micro-pollutants via various reactive radicals,but it also led to the changes of natural organic matter(NOM)and formation of disinfection byproducts(DBPs).By using negative ion electrospray ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry(ESI FT-ICR MS),the transformation of Suwannee River NOM(SRNOM)and the formation of chlorinated DBPs(Cl-DBPs)in the UV/chlorine AOP and subsequent post-chlorination were tracked and compared with dark chlorination.In comparison to dark chlorination,the involvement of Cl O·,Cl·,and HO·in the UV/chlorine AOP promoted the transformation of NOM by removing the compounds owning higher aromaticity(AI mod)value and DBE(double-bond equivalence)/C ratio and causing the decrease in the proportion of aromatic compounds.Meanwhile,more compounds which contained only C,H,O,N atoms(CHON)were observed after the UV/chlorine AOP compared with dark chlorination via photolysis of organic chloramines or radical reactions.A total of 833 compounds contained C,H,O,Cl atoms(CHOCl)were observed after the UV/chlorine AOP,higher than 789 CHOCl compounds in dark chlorination,and one-chlorine-containing components were the dominant species.The different products from chlorine substitution reactions(SR)and addition reactions(AR)suggested that SR often occurred in the precursors owning higher H/C ratio and AR often occurred in the precursors owning higher aromaticity.Post-chlorination further caused the cleavages of NOM structures into small molecular weight compounds,removed CHON compounds and enhanced the formation of Cl-DBPs.The results provide information about NOM transformation and Cl-DBPs formation at molecular levels in the UV/chlorine AOP. | Xiaoxue Ruan Yingying Xiang Chii Shang Shuangshuang Cheng Jingfu Liu Zhineng Hao Xin Yang | 2021 | Journal of Environmental Sciences2021，33，4： | 5 |
| 8 | Adiponectin receptor 1 and small ubiquitin-like modifier 4 polymorphisms are associated with risk of coronary artery disease without diabetes显示文摘编码 adiponectin 受体 1 的基因( ADIPOR1 )和小象ubiquitin一样修饰词( SUMO4 ) 4 被连接了到 anti-atherogenic 效果,但是很少对是否被知道在二基因的多型性,独立行动或交往,没有 diabetes.MethodsWe genotyped ,影响冠的动脉疾病( CAD )的风险没有糖尿病的 200 个 CAD 病人和没有 CAD 的 200 控制,它被选择基于前一个没有 diabetes.ResultsRisk 等位基因,协会也是的潜力在 ADIPOR1 (rs7539542-G, rs7514221-C 和 rs3737884-G ) 在三 SNP 在这些 SNP 和 CAD 的临床的特征之间探索了,没有糖尿病,在在 SUMO4 的 SNP rs237025 的 G 等位基因显著地增加了 CAD 的风险,与从 1.79 ~ 4.44 的 ORs。任何这四风险等位基因的搬运人出现了类似不利 ? 临床的特征。与有 CC 或 GC 遗传型的个人相比,有在 rs3737884 的 GG 遗传型的那些在影响了左前面的下降冠的动脉的 CAD 的显著地更高的风险(或:6.77, P = 0.009 ) ,恰好冠的动脉(或:4.81, P = 0.028 ) 或容器的一个相对大的数字(P = 0.04 ) 。没有糖尿病,在 SUMO4 在 SNP 象风险等位基因一样在 ADIPOR1 在三 SNP 中的至少一个带风险等位基因的个人比不带任何风险等位基因的个人在 CAD 的显著地更高的风险(或:5.82, 95% CI:1.2327.7, P = 0.013 ) 没有糖尿病,在 ADIPOR1 和 SUMO4 的 .ConclusionsSNPs 与 CAD 的提高的风险被联系,并且在二基因的 SNP 可以交往联合影响疾病风险。 | Hong LI Ze YANG Lian-Mei PU Xiang LI Yang RUAN Fan YANG Shuai MENG Duo YANG Wei YAO Hao FU Feng ZHANG Ze-Ning JIN | 2016 | Journal of Geriatric Cardiology2016，13，9： | 4 |
| 9 | A Power and Area Optimization Approach of Mixed Polarity Reed-Muller Expression for Incompletely Specified Boolean Functions显示文摘力量和芦苇思考(RM ) 电路的区域优化广泛地被担心了。然而,几乎没有退出的力量和区域,优化来临能获得所有 Pareto 原版的最佳的答案问题并且足够有效。而且,他们没认为 dont 是照顾术语,它使电路成为性能不能进一步优化。在这糊,我们建议混合极性 RM 的一条力量和区域优化途径为不完全地指定的布尔功能的表示(MPRM ) 基于非统治的排序基因算法 II (NSGA-II ) 。第一,不完全地指定的布尔功能不完全地被转变成零极性由使用的指定 MPRM (ISMPRM ) 一篇小说 ISMPRM 获得算法。第二,极性和分配 ISMPRM 的照顾术语没作为染色体被编码。最后, Pareto 最佳的答案被使用 NSGA-II 获得,在里面哪个 MPRM 相应于给定的染色体被使用一个染色体获得变换算法。结果上重要力量和区域改进能与存在力量和区域优化相比被做的电路表演 RM 接近的不完全地指定的布尔功能和 MCNC 基准电路。 | Zhen-Xue He Li-Min Xiao Li Ruan Fei Gu Zhi-Sheng Huo Guang-Jun Qin Ming-Fa Zhu F Long-Bing Zhang Rui Liu Xiang Wang | 2017 | Journal of Computer Science & Technology2017，32，2： | 4 |
| 10 | The seismicity and tectonic stress field characteristics of the Longmenshan fault zone before the Wenchuan M_S8.0 earthquake显示文摘The seismicity of Longmenshan fault zone and its vicinities before the 12 May 2008 Wenchuan MS8.0 earthquake is studied.Based on the digital seismic waveform data observed from regional seismic networks and mobile stations, the focal mechanism solutions are determined.Our analysis results show that the seismicities of Longmenshan fault zone before the 12 May 2008 Wenchuan earthquake were in stable state.No obvious phenomena of seismic activity intensifying appeared.According to focal mechanism solutions of some small earthquakes before the 12 May 2008 Wenchuan earthquake, the direction of principal compressive stress P-axis is WNW-ESE.The two hypocenter fault planes are NE-striking and NW-striking.The plane of NE direction is among N50o?70oE, the dip angles of fault planes are 60o?70o and it is very steep.The faultings of most earthquakes are dominantly characterized by dip-slip reverse and small part of faultings present strike-slip.The azimuths of principal compressive stress, the strikes of source fault planes and the dislocation types calculated from some small earthquakes before the 12 May 2008 Wenchuan earthquake are in accordance with that of the main shock.The average stress field of micro-rupture along the Longmenshan fault zone before the great earthquake is also consistent with that calculated from main shock.Zipingpu dam is located in the east side 20 km from the initial rupture area of the 12 May 2008 Wenchuan earthquake.The activity increment of small earthquakes in the Zipingpu dam is in the period of water discharging.The source parameter results of the small earthquakes which occurred near the initial rupture area of the 12 May 2008 Wenchuan earthquake indicate that the focal depths are 5 to 14 km and the source parameters are identical with that of earthquake. | Zhiwei Zhang Wanzheng Cheng Xiang Ruan Peng Wu | 2009 | Earthquake Science2009，22，2： | 3 |
| 11 | Robust minimum-variance time-reversal beamforming for target detection and localization in uncertain environment显示文摘在有颠倒( TR )技术是 investigated.TR 的柔韧的时间的不明确的环境的目标察觉和本地化是物理进程以及信号 processing.Therefore 的一个方法,经由 TR 执行 beamforming 是自然的,即, TR beamforming ( TRBF ) .To 还原剂 TR 上的环境无常的效果时间空间的集中,播送 TRBF 与当模特儿而不是物理探查来源被学习,有斜装载的柔韧的最小变化的收到 TRBF 被放 forward. | RUAN Yidi PAN Xiang LI Jianlong GONG Xianyi | 2010 | Chinese Journal of Acoustics2010，29，1： | 3 |
| 12 | Spatio-temporal variation and focal mechanism of the Wenchuan M_S8.0 earthquake sequence显示文摘Based on abundant aftershock sequence data of the Wenchuan MS8.0 earthquake on May 12, 2008, we studied the spatio-temporal variation process and segmentation rupture characteristic.Dense aftershocks distribute along Longmenshan central fault zone of NE direction and form a narrow strip with the length of 325 km and the depth between several and 40 km.The depth profile(section of NW direction) vertical to the strike of aftershock zone(NE direction) shows anisomer-ous wedgy distribution characteristic of aftershock concentrated regions;it is related to the force form of the Longmenshan nappe tectonic belt.The stronger aftershocks could be divided into northern segment and southern segment apparently and the focal depths of strong aftershocks in the 50 km area between northern segment and southern segment are shallower.It seems like ‘to be going to rupture' segment.We also study focal mechanisms and segmentation of strong aftershocks.The principal compressive stress azimuth of aftershock area is WNW direction and the faulting types of aftershocks at southern and northern segment have the same proportion.Because aftershocks distribute on different secondary faults, their focal mechanisms present complex local tectonic stress field.The faulting of seven strong earthquakes on the Longmenshan cen-tral fault is mainly characterized by thrust with the component of right-lateral strike-slip.Meantime six strong aftershocks on the Longmenshan back-range fault and Qingchuan fault present strike-slip faulting.At last we discuss the complex segmen-tation rupture mechanism of the Wenchuan earthquake. | Wanzheng Cheng Zhiwei Zhang Xiang Ruan | 2009 | Earthquake Science2009，22，2： | 2 |
| 13 | The Effects of Hydrogen-Rich Saline on the Contractile and Structural Changes of Intestine Induced by Ischemia-Reperfusion in Rats显示文摘 | Han Chen Yan Ping Sun Ping Fang Hu Wen Wu Liu Hong Gang Xiang Yang Li Rong Lin Yan Ning Su Can Ping Ruan Xue Jun Sun Qiang Wang | 2011 | Journal of Surgical Research2011，，2： | 2 |
| 14 | Hydrogen-rich saline ameliorates the severity of l -arginine-induced acute pancreatitis in rats显示文摘 | Han Chen Yan Ping Sun Yang Li Wen Wu Liu Hong Gang Xiang Lie Ying Fan Qiang Sun Xin Yun Xu Jian Mei Cai Can Ping Ruan Ning Su Rong Lin Yan Xue Jun Sun Qiang Wang | 2010 | Biochemical and Biophysical Research Communications2010，，2： | 2 |
| 15 | 基于综合集成研讨厅的群体智能设计研究(英文)显示文摘本文提出了一种基于综合集成研讨厅的群体智能设计技术,包括系统的体系架构、基于综合集成研讨的设计决策过程以及设计资源推送技术,最后在对本文工作进行总结的基础上,对下一步研究方向进行了展望。 | Bo-hu LI Hui-yang QU Ting-yu LIN Bao-cun HOU Xiang ZHAI Guo-qiang SHI Jun-hua ZHOU Chao RUAN | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，1： | 2 |
| 16 | Efficacy,safety and immunogenicity of hexavalent rotavirus vaccine in Chinese infants显示文摘A randomized,double-blind,placebo-controlled multicenter trial was conducted in healthy Chinese infants to assess the efficacy and safety of a hexavalent live human-bovine reassortant rotavirus vaccine(HRV)against rotavirus gastroenteritis(RVGE).A total of 6400 participants aged 6-12 weeks were enrolled and randomly assigned to either HRV(n?3200)or placebo(n?3200)group.All the subjects received three oral doses of vaccine four weeks apart.The vaccine efficacy(VE)against RVGE caused by rotavirus serotypes contained in HRV was evaluated from 14 days after three doses of administration up until the end of the second rotavirus season.VE against severe RVGE,VE against RVGE hospitalization caused by serotypes contained in HRV,and VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were also investigated.All adverse events(AEs)were collected for 30 days after each dose.Serious AEs(SAEs)and intussusception cases were collected during the entire study.Our data showed that VE against RVGE caused by serotypes contained in HRV was 69.21%(95%CI:53.31-79.69).VE against severe RVGE and RVGE hospitalization caused by serotypes contained in HRV were 91.36%(95%CI:78.45-96.53)and 89.21%(95%CI:64.51-96.72)respectively.VE against RVGE,severe RVGE,and RVGE hospitalization caused by natural infection of any serotype of rotavirus were 62.88%(95%CI:49.11-72.92),85.51%(95%CI:72.74-92.30)and 83.68%(95%CI:61.34-93.11).Incidences of AEs from the first dose to one month post the third dose in HRV and placebo groups were comparable.There was no significant difference in incidences of SAEs in HRV and placebo groups.This study shows that this hexavalent reassortant rotavirus vaccine is an effective,well-tolerated,and safe vaccine for Chinese infants. | Zhiwei Wu Qingliang Li Yan Liu Huakun Lv Zhaojun Mo Fangjun Li Qingchuan Yu Fei Jin Wei Chen Yong Zhang Teng Huang Xiaosong Hu Wei Xia Jiamei Gao Haisong Zhou Xuan Bai Yueyue Liu Zhenzhen Liang Zhijun Jiang Yingping Chen Jiuwei Zhang Jialiang Du Biao Yang Bo Xing Yantao Xing Ben Dong Qinghai Yang Chen Shi Tingdong Yan Bo Ruan Haiyun Shi Xingliang Fan Dongyang Feng Weigang Lv Dong Zhang Xiangchu Kong Liuyifan Zhou Dinghong Que Hong Chen Zhongbing Chen Xiang Guo Weiwei Zhou Cong Wu Qingrong Zhou Yuqing Liu Jian Qiao Ying Wang Xinguo Li Kai Duan Yuliang Zhao Gelin Xu Xiaoming Yang | 2022 | Virologica Sinica2022，37，5： | 2 |
| 17 | Research on the Dynamic Change of Regional Stress Fields before the M_S8.0 Wenchuan Earthquake显示文摘Using the digital telemetric seismic waveform data of Chengdu and Kunming, this article studies the focal mechanism solutions and the apparent stress values of a large number of small earthquakes, and then analyzes the dynamic variation of regional stress fields and the spatio-temporal distribution of apparent stress values. The annual variation values of the azimuth of average principal stress field before the May 12, 2008 M_S8.0 Wenchuan earthquake in the Sichuan-Yunnan region were 58° from 2003 to 2004, 85° from 2003 to 2005,61° from 2006 to 2007 and 90° from 2006 to April 2008 respectively. In recent years, deflection or disturbances occurred in the azimuth of the average principal stress field in the Sichuan-Yunnan region. Analysis shows that this may be related to the change of stress field states of crustal blocks before and after the December 26, 2004 M_S9.0 Sumatra earthquake and the 2008 M_S8.0 Wenchuan earthquake. The ratio of thrust-type earthquakes in the Sichuan-Qinghai block was on the higher side in the period from 2006 to 2007, and the source faulting type of the regional moderate and small earthquakes had changed before the M_S8.0 Wenchuan earthquake. The change of state of the stress field is consistent with the changes in block displacement fields revealed by GPS data and the crustal shortening velocity vertical to the Longmenshan fault zone. Based on the radiation energy calculated from all bands of the seismic waveform, the value of apparent stress σ_app is obtained. The fluctuation shape of the fitting trend of the apparent stress is related to the intensity of regional seismicity. It reveals that the micro-dynamic fluctuation process of the regional stress value is similar to the azimuth transition of the regional principal compressive stress field, which can be used to probe for pregnant physical processes. Areas with a higher value of apparent stress σ_app are possible areas of potential seismic risk. It can be seen from the spatial distribution of the medium and short-term apparent stress σ_app before the M_S8.0 Wenchuan earthquake, the Longmenshan fault zone is in a low stress distribution area, and the relatively high apparent stress is in the peripheral area. These images may show medium and short-term locking phenomena near the seismogenic tectonics of the M_S8.0 Wenchuan earthquake. For example, changes with time of the focal parameter consistency of the sub-blocks in Sichuan and Yunnan Provinces, continual increase of thrust-type earthquakes in the Sichuan-Qinghai block and the appearance of spatial distribution areas of high apparent σ_app stress. The work on this aspect was continued after the M_S8.0 Wenchuan earthquake, and the results seem to be shown a clearer relationship between these phenomena and future great earthquakes. | Cheng Wanzheng Ruan Xiang Qiao Huizhen Zhang Zhiwei Zhang Yongjiu | 2009 | Earthquake Research in China2009，23，3： | 2 |
| 18 | 2D Digital Simplified Servo Valve显示文摘 | Ruan Jian Li Sheng Pei Xiang | 2004 | Chinese Journal of Meehanieal En- gineering2004，17，2： | 1 |
| 19 | 3-D finite element simulation of the vertical-horizontal rolling process 显示文摘 | RUAN Jin-hua ZHANG Li-wen YUE Chong- xiang etal | 2011 | Advanced Materials Research2011，145，： | 1 |
| 20 | Pore Pressure Accumulation of Anisotropically Consolidated Soft Clay Subjected to Complex Loads Under Different Stress Paths显示文摘Owing to different influence factors of foundation soil,the initial stress state of the soil under various working conditions is complex.To simulate this situation,in this paper,a series of tests on undisturbed soft clay under pure principal stress axis rotation were carried out by using the hollow cylinder apparatus(HCA).The influence of initial consolidation angle ζ(the angle between the vertical direction and direction of the applied load in consolidation)and intermediate principal stress coefficient b on pore water pressure accumulation of undisturbed soft clay were mainly studied.The test results show that,during pure principal stress axis rotation,the pore water pressure accumulation of the undisturbed soft clay fluctuates and increases with the rotation of the major principal stress;the values of major principal stress anglesα,corresponding to the peak value of the pore water pressure in a certain cycle,are different with different initial consolidation angles;the pore water pressure accumulation of soft clay is greatly affected by the intermediate principal stress coefficient b.With the fixed initial consolidation angle ζ,the variation trend of the maximum pore water pressure for each cycle is appropriately the same with different b values.With the increase of cycles,the difference value of pore water pressure between b=0 and b=1 in each cycle increases gradually with different initial consolidation angles ζ.While with different initial consolidation anglesζ,the increase of the pore water pressure when b increases from 0 to 0.5 is different with that when b increases from 0.5 to 1;the variation of maximum pore water pressure withζis significantly affected by the value of b;the value of maximum pore water pressure increases with the cycle number increases under all test conditions,but the growth rate decreases gradually.And the variation of maximum pore water pressure with the cycle number N is obviously influenced by both ζ and b. | WANG Yu-ke WAN Yong-shuai RUAN Hang YU Xiang SHAO Jing-gan REN De-bo | 2021 | China Ocean Engineering2021，35，3： | 1 |
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