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| 1 | 弥漫性中线胶质瘤,组蛋白H3-K27M突变型:47例形态学变异谱系及相关遗传学改变分析显示文摘最近发现在儿童和年轻人丘脑、桥脑和脊髓的高级别胶质瘤中存在编码组蛋白H3的亚型H3.3和H3.1的H3F3A和HIST1H3B基因体细胞突变。然而,关于发生这些肿瘤的患者和部位具体范围,以及形态学谱系和相关遗传学改变仍然不确定。本文检测47例伴组蛋白H3-K27M突变的弥漫性中线胶质瘤,包括25例男性和22例女性患者,年龄2~65岁(中位年龄14岁)。肿瘤中心位置除了位于桥脑(17例)、丘脑(15例)和脊髓(9例),还可见于第三脑室(3例)、下丘脑(1例)、松果体区(1例)和小脑(1例)。 | Solomon D A Wood M D Tihan T 李晓玲 王行富 | 2016 | 临床与实验病理学杂志2016，32，9： | 49 |
| 2 | Hepatitis B and C infection and liver disease trends among human immunodeficiency virus-infected individuals显示文摘AIM:To examine trends in and correlates of liver disease and viral hepatitis in an human immunodeficiency virus (HIV)-infected cohort. METHODS:The multi-site adult/adolescent spectrum of HIV-related diseases (ASD) followed 29 490 HIVinfected individuals receiving medical care in 11 U.S. metropolitan areas for an average of 2.4 years,and a total of 69 487 person-years,between 1998 and 2004. ASD collected data on the presentation,treatment,and outcomes of HIV,including liver disease,hepatitis screening,and hepatitis diagnoses. RESULTS:Incident liver disease,chronic hepatitis B virus (HBV),and hepatitis C virus (HCV) were diagnosed in 0.9,1.8,and 4.7 per 100 person-years. HBV and HCV screening increased from fewer than 20% to over 60% during this period of observation (P < 0.001). Deaths occurred in 57% of those diagnosed with liver disease relative to 15% overall (P < 0.001). Overall 10% of deaths occurred among individuals with a diagnosis of liver disease. Despite care guidelines promoting screening and vaccination for HBV and screening for HCV,screening and vaccination were not universally conducted or,if conducted,not documented. CONCLUSION:Due to high rates of incident liver disease,viral hepatitis screening,vaccination,and treatment among HIV-infected individuals should be a priority. | Susan E Buskin Elizabeth A Barash John D Scott David M Aboulafia Robert W Wood | 2011 | World Journal of Gastroenterology2011，17，14： | 2 |
| 3 | 年龄相关性线粒体功能障碍加速动脉粥样硬化形成显示文摘老化是动脉粥样硬化的最强危险因素之一。然而,老化是否独立于慢性高血脂症而增加动脉粥样硬化的风险尚不清楚。该研究旨在确定高血脂症诱导前的血管老化是否会加速动脉粥样硬化的形成。研究者分析了幼年和老年正常血脂野生型(wild type,WT)、无疾病小鼠的主动脉,发现老化导致白细胞介素(interleukin,IL)6水平升高和线粒体功能障碍,并与线粒体自噬增加和其相关蛋白Parkin增加相关。在主动脉组织培养中,研究者发现随着老化的出现,线粒体功能障碍与IL-6存在正反馈关系。研究者通过诱导低密度脂蛋白受体的肝脏特异性降解,再结合10周的西方食物喂养,在老年和幼年小鼠中诱发急性高血脂症,发现老年WT小鼠的动脉粥样硬化增强。高血脂症进一步降低了老年小鼠的线粒体功能,增加了主动脉中Parkin的水平,但幼鼠则没有。 | 刘青(译) 叶鹏(摘、审校) Tyrrell DJ Blin M Song J Wood S Zhang M Beard DA Goldstein D | 2020 | 中华高血压杂志2020，28，2： | 2 |
| 4 | Novel and economical purification of recombinant proteins:intein-mediated protein purification using in vivo polyhydroxybutyrate (PHB) matrix association显示文摘 | BANKI M R GERNGROSS T U WOOD D W | 2005 | Protein Science2005，14，： | 1 |
| 5 | Effect of feeding organic acids on selected intestinal content measurements at varying times postweaning in pigs显示文摘 | Risley C R Kornegay E T Lindemann M D Wood C M Eigel W N | 1992 | Journal of Animal Science1992，70，： | 1 |
| 6 | Strain softening and parameter for sand modeling显示文摘 | WOOD D M BELKHEIR K SHEN C K | 1994 | Geo- technique1994，44，2： | 1 |
| 7 | Manipulating meat quality and composition 显示文摘 | WOOD J D ENSER M FISHER A V | 1999 | Proc Nutr Soc1999，58，2： | 1 |
| 8 | Senescence of human fibroblasts induced by oncogenic Raf显示文摘 | Zhu JY Woods D McMahon M | 1998 | Genes & Development1998，12，19： | 1 |
| 9 | 显示文摘 | Rieke P C Marsh B D Wood M L | 1995 | Langmuir1995，11，1： | 1 |
| 10 | Reproducibility of serology assays for pandemic influenza H1N1:collaborative study to evaluate a candidate WHO international standard显示文摘 | WOOD J M MAJOR D HEATH A | | 0，，02： | 1 |
| 11 | Simple bioseparations using self-cleaving elastin-like polypeptide tags 显示文摘 | BANKI M R FENG L WOOD D W | 2005 | Nature Methods2005，2，： | 1 |
| 12 | Human DNA repair genes 显示文摘 | Wood R D Mitchell M Sgouros J | 2001 | Science2001，291，： | 1 |
| 13 | Severn-trent sand: a kinematic- hardening constitutive model: the q-p formulation显示文摘 | GAJO A WOOD D M | 1999 | Geoteehnique1999，49，5： | 1 |
| 14 | The role of nanobacteria in urologic disease显示文摘 | WOOD H M SHOSKES D A | 2006 | World Uro12006，24，1： | 1 |
| 15 | Central nervous system control of food intake显示文摘 | Schwartz M W Woods S C Porte D Jr | 2000 | Nature2000，404，： | 1 |
| 16 | Directed evolution of ionizing radiation resistance in Escherichia coli 显示文摘 | Harris D R Pollock S V Wood E A Goiffon R J Klingele A J Cabot E L Schackwitz W Martin J Eggington J Durfee T J Middle C M Norton J E Popelars M C Li H Klugman S A Hamilton L L Bane L B Pennacchio L A Albert T J Perna N T Cox M M Battista J R | 2009 | Journal of Bacteriology2009，191，16： | 1 |
| 17 | 2006 Bethesda International Consensus recommendations on the immunophenotypic analysis of hematolymphoid neoplasia by flow cytometry:optimal reagents and reporting for the flow cytometric diagnosis of hematopoietic neoplasia显示文摘 | Wood BL Arroz M Barnett D | | 0，，01： | 1 |
| 18 | Backfat composition in pigs: Differences between fat thickness groups and sexes 显示文摘 | WOOD J D ENSER M WHITTINGTON F M | 1989 | Livestock Production Science1989，22，34： | 1 |
| 19 | Heterotrophic nitrification in an acidforest soil:isolation and characterisation of a nitrifying bacterium显示文摘 | Brierley E D R Wood M | 2001 | Soil Biology and Biochemistry2001，33，10： | 1 |
| 20 | Disco-vering shared interests u-sing graph analysis显示文摘 | SCHWARTZ M F WOOD D C M | 1993 | Communications of the ACM1993，36，8： | 1 |
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