共被期刊论文引用了2次
您的检索式：您选中1篇文献正在查看引证文献汇总
|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Roles and mechanisms of exosomal non-coding RNAs in human health and diseases显示文摘Exosomes play a role as mediators of cell-to-cell communication,thus exhibiting pleiotropic activities to homeostasis regulation.Exosomal non-coding RNAs(ncRNAs),mainly microRNAs(miRNAs),long non-coding RNAs(lncRNAs),and circular RNAs(circRNAs),are closely related to a variety of biological and functional aspects of human health.When the exosomal ncRNAs undergo tissuespecific changes due to diverse internal or external disorders,they can cause tissue dysfunction,aging,and diseases.In this review,we comprehensively discuss the underlying regulatory mechanisms of exosomes in human diseases.In addition,we explore the current knowledge on the roles of exosomal miRNAs,lncRNAs,and circRNAs in human health and diseases,including cancers,metabolic diseases,neurodegenerative diseases,cardiovascular diseases,autoimmune diseases,and infectious diseases,to determine their potential implication in biomarker identification and therapeutic exploration. | Chen Li Yu-Qing Ni Hui Xu Qun-Yan Xiang Yan Zhao Jun-Kun Zhan Jie-Yu He Shuang Li You-Shuo Liu | 2021 | Signal Transduction and Targeted Therapy2021，6，12： | 3 |
| 2 | Nanoparticles in the diagnosis and treatment of vascular aging and related diseases显示文摘Aging-induced alternations of vasculature structures,phenotypes,and functions are key in the occurrence and development of vascular aging-related diseases.Multiple molecular and cellular events,such as oxidative stress,mitochondrial dysfunction,vascular inflammation,cellular senescence,and epigenetic alterations are highly associated with vascular aging physiopathology.Advances in nanoparticles and nanotechnology,which can realize sensitive diagnostic modalities,efficient medical treatment,and better prognosis as well as less adverse effects on non-target tissues,provide an amazing window in the field of vascular aging and related diseases.Throughout this review,we presented current knowledge on classification of nanoparticles and the relationship between vascular aging and related diseases.Importantly,we comprehensively summarized the potential of nanoparticles-based diagnostic and therapeutic techniques in vascular aging and related diseases,including cardiovascular diseases,cerebrovascular diseases,as well as chronic kidney diseases,and discussed the advantages and limitations of their clinical applications. | Hui Xu Shuang Li You-Shuo Liu | 2022 | Signal Transduction and Targeted Therapy2022，7，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员