|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Engineered trimeric ACE2 binds viral spike protein and locks it in'Thfee-up'conformation to potently inhibit SARS-CoV-2 infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has resulted in a severe global pandemic Following SARS-CoV,SARS-CoV-2 is yet another emerge nt beta-coronavirus threate ning human health.1 However,seventeen years after the SARS pandemic,no targeted vaccines or therapeutics have been approved for SARS,while some of them might have held promise for treating COVID-19.Many neutralizing antibodies against SARS-CoV-2 are currently being developed.However,RNA viruses are known to have high mutation rates. | Liang Guo Wenwen Bi Xinling Wang Wei Xu Renhong Yan Yuanyuan Zhang Kai Zhao Yaning Li Mingfeng Zhang Xia Cai Shibo Jiang Youhua Xie Qiang Zhou Lu Lu Bobo Dang | 2021 | Cell Research2021，31，1： | 5 |
| 2 | Effects of Calcination Temperature on the Structure and Adsorption Performance of Ce-Mn/AC Materials显示文摘Activated carbon-supported bimetallic cerium-manganese(Ce-Mn/AC) materials were prepared by impregnation method to study the effect of calcination temperature on the structure and adsorption performance of absorbents. The obtained materials were characterized by using X-ray diffraction(XRD), scanning electron microscope(SEM), N_2 adsorption-desorption isotherm, Fourier transformed infrared(FT-IR), and X-ray photoelectron spectroscopy(XPS). As the results showed, the diffraction peaks of CeO_2 decreased and even disappeared; Mn species were transformed from Mn_3O_4 to Mn_2O_3 on the surface of Ce-Mn/AC; the BET specific surface area increased first and then decreased on the elevating calcination temperature; the number of acid functions of AC was reduced after being modified by cerium and manganese. All these changes were directly attributed to the synergistic effects between Mn Ox and CeO_2. AC800 exhibited the best phenol adsorption capacity. The adsorption mechanism of phenol on Ce-Mn/AC was discussed with hydrophilic(hydrophobic) interaction and hard and soft acid-base theory. | GAO Wenwen ZHANG Zhifang CHEN Bi MA Xiangrong YAN Biao | 2017 | Wuhan University Journal of Natural Sciences2017，22，5： | 1 |
| 3 | Enhanced trimeric ACE2 exhibits potent prophylactic and therapeutic efficacy against the SARS-CoV-2 Delta and Omicron variants in vivo显示文摘Dear Editor,The outbreak of coronavirus disease 2019(COVID-19)has resulted in a severe global pandemic that has lasted for more than two years.1 Several vaccines were developed at an unprecedented speed to protect billions of people.2 Many monoclonal antibodies have also been discovered,several of which are in the clinical stages.3 However,limited vaccine availability and vaccine hesitancy compromise the impact of vaccines.The continuous evolution of SARS-CoV-2 has also resulted in many variants that can escape immunity,reducing the effects of vaccines and antibodies.4 With more than 30 mutations in the spike protein,the Omicron variant escapes the majority of existing antibodies and extensively evades vaccine-induced immunity.5,6 Thus,therapeutics that are broadly effective against current and future emerging SARS-CoV-2 variants are still highly desirable. | Mengjiao Li Zi-Wei Ye Kaiming Tang Liang Guo Wenwen Bi Yuyuan Zhang Yan-dong Tang Guoguang Rong Mohamad Sawan Xin Yin Ren Sun Shuofeng Yuan Bobo Dang | 2022 | Cell Research2022，32，6： | 1 |
| 4 | Analysis and Nursing Health Education of Current Status of Maintenance Hemodialysis Patients with Hyperphosphatemia显示文摘Concerned about the current situation of hemodialysis patients'awareness of the problems related to dialysis complicated with hyperphosphatemia,further analyze the existing problems and causes,give targeted and individualized health education,improve the compliance of diet,medication and self-management,strengthen nurse-patient communication,establish a good nurse-patient relationship,reduce and control the incidence of hyperphosphatemia,improve patients'quality of life,and improve prognosis. | Wenwen He Yingyi Bi Hongjiao Xu Liqian Gao Xing Zhao | 2020 | Journal of Advances in Medicine Science2020，3，2： | 1 |
| 5 | Arbuscular mycorrhizal symbiosis facilitates apricot seedling(Prunus sibirica L.)growth and photosynthesis in northwest China显示文摘Arbuscular mycorrhizal(AM)fungi can successfully enhance photosynthesis(P_(n))and plants growth in agricultural or grassland ecosystems.However,how the symbionts affect species restoration in sunlight-intensive areas remains largely unexplored.Therefore,this study’s objective was to assess the effect of AM fungi on apricot seedling physiology,within a specific time period,in northwest China.In 2010,an experimental field was established in Shaanxi Province,northwest China.The experimental treatments included two AM fungi inoculation levels(0 or 100 g of AM fungal inoculum per seedling),three shade levels(1900,1100,and 550µmol m^(−2) s^(−1)),and three ages(1,3,and 5 years)of transplantation.We examined growth,Pn,and morphological indicators of apricot(Prunus sibirica L.)seedling performances in 2011,2013,and 2015.The colonization rate in mycorrhizal seedlings with similar amounts of shade is higher than the corresponding controls.The mycorrhizal seedling biomass is significantly higher than the corresponding non-mycorrhizal seedling biomass.Generally,P_(n),stomatal conductance(G_(s)),transpiration rate(T_(r)),and water use efficiency are also significantly higher in the mycorrhizal seedlings.Moreover,mycorrhizal seedlings with light shade(LS)have the highest Pn.WUE is increased in non-mycorrhizal seedlings because of the reduction in T_(r),while T_(r) is increased in mycorrhizal seedlings with shade.There is a significant increase in the N,P,and K fractions detected in roots compared with shoots.This means that LS had apparent benefits for mycorrhizal seedlings.Our results also indicate that AM fungi,combined with LS,exert a positive effect on apricot behavior. | Yinli Bi Linlin Xie Zhigang Wang Kun Wang Wenwen Liu Wenwu Xie | 2021 | International Journal of Coal Science & Technology2021，8，4： | 0 |
| 6 | Atomically Precise Metal Nanoclusters as Single Electron Transferers for Hydroborylation显示文摘The emergence of metal nanoclusters with atomically precise compositions and structures provides an opportunity for in-depth investigation of catalysis mechanisms and structure−property correlations at the nanoscale.However,a serious problem for metal nanocluster catalysts is that the ligands inhibit the catalytic activity through deactivating the surface of the nanoclusters.Here,we introduce a novel catalytic mode for metal nanoclusters,in which the nanoclusters initiate the catalysis via single electron transfer(SET)without destroying the integrity of nanoclusters,providing a solution for the contradiction between activity and stability of metal nanoclusters.We illustrated that the novel activation mode featured low catalyst loading(0.01 mol%),high TOF,mild reaction conditions,and easy recycling of catalyst in alkyne hydroborylation,which often suffered from poor selectivity,low functional group tolerance,etc.Furthermore,the catalyst[Au_(1)Cu_(14)(TBBT)_(12)(PPh_(3))_(6)]^(+)(TBBTH:p-tert-butylthiophenol)can be applied in highly efficient tandem processes such as hydroborylation−deuteration and hydroborylation−isomerization,demonstrating the utility of the introduced activation mode for metal nanoclusters. | Wanli Zhu Sheng Zhang Weigang Fan Ying Yang Hongliang Zhao Wenwen Fei Hong Bi Jian He Man-Bo Li Zhikun Wu | 2023 | Precision Chemistry2023，1，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员