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| 1 | Metabolic profiling analysis of a D-galactosamine/lipopolysaccharide- induced mouse model of fulminant hepatic failure显示文摘 | Feng, B Wu, SM Lv, S Liu, F Chen, HS Yan, XZ Li, Y Dong, FT Wei, L | 2007 | 中国生物学文摘2007，21，11： | 23 |
| 2 | Leber's hereditary optic neuropathy is associated with the mitochondrial ND4 G11696A mutation in five Chinese families显示文摘 | Zhou XT Wei QP Yang L Tong Y Zhao FX Lu CJ Qian YP Sun YH Lu F Qu J Guan MX | 2006 | 中国生物学文摘2006，20，4： | 18 |
| 3 | Interleukin-10 gene polymorphisms and hepatocellular carcinoma susceptibility:A meta-analysis显示文摘AIM: To assess the association between Interleu-kin-10 (IL-10) gene IL-10-1082 (G/A), IL-10-592(C/A), IL-10-819 (T/C) polymorphisms and hepatocellular carcinoma (HCC) susceptibility.METHODS: Two investigators independently searched the Medline, Embase, China National Knowledge Infrastructure, and Chinese Biomedicine Database. Summary odds ratios (ORs) and 95% conf idence intervals (95% CIs) for IL-10 polymorphisms and HCC were cal-culated in a fixed-effects model (the Mantel-Haenszel method) and a random-effects model (the DerSimonian and Laird method) when appropriate. RESULTS: This meta analysis included seven eligiblestudies, which included 1012 HCC cases and 2308 controls. Overall, IL-10-1082 G/A polymorphism was not associated with the risk of HCC (AA vs AG + GG, OR = 1.11, 95% CI = 0.90-1.37). When stratifying for ethnicity, the results were similar (Asian, OR = 1.12, 95% CI = 0.87-1.44; non-Asian, OR = 1.10, 95% CI = 0.75-1.60). In the overall analysis, the IL-10 polymorphism at position -592 (C/A) was identified as a genetic risk factor for HCC among Asians; patients carrying the IL-10-592*C allele had an increased risk of HCC (OR = 1.29, 95% CI = 1.12-1.49). No association was observed between the IL-10-819 T/C polymorphism and HCC susceptibility (TT vs TC + CC, OR = 1.02, 95% CI = 0.79-1.32).CONCLUSION: This meta-analysis suggests that IL-10-592 A/C polymorphism may be associated with HCC among Asians. IL-10-1082 G/A and IL-10-819 T/C polymorphisms were not detected to be related to the risk for HCC. | Yong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin YangYong-Gang Wei, Fei Liu, Bo Li, Xi Chen, Yu Ma, Lv-Nan Yan, Tian-Fu Wen, Ming-Qing Xu, Wen-Tao Wang, Jia-Yin Yang, Department of Liver and Vascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Prov- ince, China Author contributions: Wei YG and Liu F designed the study, collected and analyzed the data and wrote the manuscript Li B collected and analyzed the data and wrote the manuscript Chen X and Ma Y collected and analyzed the data Yan LN analyzed the data and contributed to the discussion Wen TF and Xu MQ revised the manuscript Wang WT and Yang JY contributed to the discussion Wei YG and Liu F contributed equally to this work. | 2011 | World Journal of Gastroenterology2011，17，34： | 3 |
| 4 | Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility:a case-control analysis显示文摘The BRCA1 Associated RING Domain(BARD1) gene has been identified as a high penetrance gene for breast cancer, whose germline and somatic mutations were reported in both non-BRCA1/2 hereditary site-specific and sporadic breast cancer cases. BARD1 plays a crucial role in tumor repression, along with its heterodimeric partner BRCA1. In the current study, we tested the hypothesis that common non-synonymous polymorphisms in BARD1 are associated with breast cancer susceptibility in a case-control study of 507 patients with incident breast cancer and 539 frequency-matched cancer-free controls in Chinese women. We genotyped all three common(minor allele frequency (MAF) > 0.10) non-synonymous polymorphisms(Pro24Ser, Arg378Ser, and Val507Met) in BARD1. We found that the BARD1 Pro24Ser variant genotypes(24Pro/Ser and 24Ser/Ser) and Arg378Ser variant homozygote 378Ser/Ser were associated with a significantly decreased breast cancer risk, compared with their wild-type homozygotes, respectively. Furthermore, a significant locus-locus interaction was evident between Pro24Ser and Arg378Ser (P-int = 0.032). Among the 378Ser variant allele carriers, the 24Pro/Pro wild-type homozygote was associated with a significantly increased breast cancer risk (adjusted OR = 1.81, 95% CI = 1.11-2.95), but the subjects having 24Pro/Ser or Ser/Ser variant genotypes had a significantly decreased risk(adjusted OR = 0.74, 95% CI = 0.56-0.99). In stratified analysis, this locus-locus interaction was more evident among subjects without family cancer history, those with positive estrogen receptor (ER) and individuals with negative progesterone receptor(PR). These findings indicate that the potentially functional polymorphisms Pro24Ser and Arg378Ser in BARD1 may jointly contribute to the susceptibility of breast cancer. | Huo, X Hu, Z. B Zhai, X. J Wang, Y Wang, S Wang, X. C Qin, J. W Chen, W. S Jin, G. F Liu, J. Y Gao, J Wei, Q. Y Wang, X. R Shen, H. B | 2007 | 南京医科大学学报(自然科学版)2007，27，7： | 3 |
| 5 | An antagonist decoy receptor and a death domain-containing receptor for TRAIL 显示文摘 | Pan G Ni J Wei Y F | 1997 | Science1997，277，5327： | 2 |
| 6 | UV curing behavior of methacrylated hyperbranched poly (amine-ester) s 显示文摘 | Wei H Y Lu Y Shi W F | 2001 | Journal of Applied Polymer Science2001，80，1： | 1 |
| 7 | Inverse algorithm for tsunami forecasts显示文摘 | Wei Y Cheung K F Curtis G D | 2003 | J Waterw Port Coastal Ocean Eng2003，129，2： | 1 |
| 8 | Effect of pore structure on Ni catalyst for CO2 reforming of CH4显示文摘 | SUN N WEN X WANG F WEI W SUN Y | 2010 | Energy Environ Sci2010，3，3： | 1 |
| 9 | Chemical modification of L-asparaginase from Escherichia coli with a modified polyethyleneglycol under substrate protection conditions显示文摘 | Zhang J F Shi L Y Wei D Z | 2004 | Biotechnology Letters2004，26，： | 1 |
| 10 | The antiadenovirus activities of cinnamaldehyde in vitro 显示文摘 | Liu L Wei F X Qu Z Y | 2009 | Lab Med2009，40，： | 1 |
| 11 | Abiogenic gas: should the carbon isotope order be reversed? 显示文摘 | Wei Z F Zou Y R Cai Y L | 2012 | Journal of Petroleum Science and Engineering2012，84，85： | 1 |
| 12 | Soybean GmbZIP44,GmbZIP62 and GmbZIP78 genes function as negative regulator of ABA signaling and confer salt and freezing tolerance in transgenic Arabidopsis显示文摘 | Liao Y Zou H F Wei W | 2008 | Planta2008，228，2： | 1 |
| 13 | Surveys of transmitted HIV drug resistance in 7 geographic regions in China, 2008-2009 显示文摘 | Liao L Xing H Dong Y Qin G Ma Y Lu H Chen L Zhang L Osborne C Seguy N Wei D Sun F Yang J Ru- an Y Shao Y | 2012 | Clin Infect Dis2012，54，4： | 1 |
| 14 | Pulmonary sequestration: a retrospective analysis of 2625 cases in China显示文摘 | Wei Y Li F | 2011 | Eur J Cardiothorae Surg2011，40，1： | 1 |
| 15 | Enhanced strain-rate sensitivity in fcc nanocrystals due to grain boundary diffusion and sliding 显示文摘 | Wei Y J Bower A F Gao H J | 2008 | Acta Materialia2008，56，： | 1 |
| 16 | Implication of boron isotope geochemistry for the pedogenic environments in loess and paleosol sequences of central China显示文摘 | Wei H Z Lei F Jiang S Y Lu H Y Xiao Y K Zhang H Z Sun X F | 2015 | Quatern Res2015，83，1： | 1 |
| 17 | Preparation and properties of novel inherent flame-retardant cyclotriphosphazene-containing epoxy resins 显示文摘 | Liu F F Wei H Huang X B Zhang J W Zhou Y B Tang X Z | 2010 | Journal of Macromolecular Science Part B: Physics2010，49，5： | 1 |
| 18 | Characterization and quantification of triacylglycerols in peanut oil by off-line comprehensive two-dimensional liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry显示文摘 | HU J WEI F DONG X Y | 2013 | J Sepsci2013，36，2： | 1 |
| 19 | Porous and lamella-like Fe/MgO catalysts prepared under hydrothermal conditions for high-yield syn thesis of double-walled carbon nanotubes显示文摘 | Ning G Q Liu Y Wei F | 2007 | J Phys Chem C2007，111，5： | 1 |
| 20 | Determination of rutin using a CeO2 nanoparticle-modified electrode显示文摘 | WEI Y WANG G F LI M G | 2007 | Microchim Acta2007，158，： | 1 |
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