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| 1 | Synergistic antibacterial effect of honey and Herba Ocimi Basilici against some bacterial pathogens显示文摘OBJECTIVE: To evaluate the antibacterial activity of the combination of different honey brands and methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS: The antibacterial activity was determined against thirteen pathogenic bacterial clinical isolates including six gram negative(Klebsiella pneumonia, Pseudomonas aeroginosa, Escherichia coli, Salmonella typhi, Salmonella typhimirium, Xanthomonas campestris) and six gram positive strains(Enterococcus faecalis faecalis, Bacillus subtilis, Staphylococcus aureus, Clostridium perfringens type C, Clostridium perfringens type D, Clostridium chauvoei). Agar well diffusion method was used while zones of inhibition were measured with vernier scale. RESULTS: At higher concentration, all the honey brands showed good to significant activity. The highest activity was observed for Hamdard brand honey(27.60±0.40) against Enterococcus faecalis. CONCLUSION: These results revealed that combinations of plant extracts of Herba Ocimi Basilici with honey can be used for the development of potent and novel antibacterial agents. | Ali Talha Khalil Imran Khan Kafeel Ahmad Yusra Ali Khan Momin Khan Muhammad Jaseem Khan | 2013 | Journal of Traditional Chinese Medicine2013，33，6： | 4 |
| 2 | Role of dietary phytochemicals in modulation of miRNA expression:Natural swords combating breast cancer显示文摘The National Cancer Institute had projected breast cancer(BC) as one of the topmost prevalent malignancies around the globe.In many cases,BC becomes resistant to chemotherapy,radiation and hormonal therapies.Traditional BC therapies are associated with adverse side effects,drug resistance and recurrence.Extensive research work has shown that these dietary phytochemicals(DPs) may exert therapeutic effects by regulating the miRNA expression.A large number of DPs have been researched as miRNA regulatory agents against BC and some other DPs have not yet been tested against BC.We have discussed the effects of curcumin,diallyl disulphide,3,3′ diindolylmethane,ellagic acid,genistein,indole-3-carbinol,quercetin,resveratrol,and sulforaphane on regulation of expression of BC miRNAs in a wide range of in vitro and in vivo models.We have also shown some of the possible DPs(Oleanolic acid,capsaicin,benzyl isothiocyanate,epigallocatechin gallate,phenethyl isothiocyanate and ursolic acid) that have shown miRNA regulatory activities and have not yet been tested against BC miRNAs.Finally,current limitations,challenges,future perspectives of DPs and BC research are also critically discussed. | Banzeer Ahsan Abbasi Javed Iqbal Tariq Mahmood Ali Talha Khalil Barkat Ali Sobia Kanwal Sayed Afzal Shah Riaz Ahmad | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，9： | 3 |
| 3 | Antibacterial activity of honey in north-west Pakistan against select human pathogens显示文摘OBJECTIVE:To investigate the antimicrobial activity of commercially available honey and raw honey samples in Khyber Pakhtunkhwa,Pakistan,against pathogenic bacterial strains.METHODS:Well diffusion assays were performed to screen pure and diluted honey samples for antibacterial activity against six Gram-negative and six Gram-positive bacterial strains.Zones of inhibition were measured and compared with 10 mg Gentamycin.RESULTS:When honey samples were diluted to20%-70%,the honey samples showed no activity to mild antibacterial activity.The highest antibacterial activity was recorded when 90%and pure undiluted honey samples were tested and compared with a control Gentamycin disc(10 mg).CONCLUSION:Commercially processed honey and raw honey samples from north-west of Pakistan possess good antimicrobial potential. | Ali Talha Khalil Imran Khan Yusra Ali Khan Zabta Khan Shinwari Kafeel Ahmad Jangrez Khan | 2014 | Journal of Traditional Chinese Medicine2014，34，1： | 2 |
| 4 | A review on protein based nanocarriers for polyphenols:interaction and stabilization mechanisms显示文摘Protein has been used as the carrier for protecting and targeting polyphenols and increasing their shelf-life.Interactions of a protein molecule with polyphenols are important,which change functions and physiochemical properties of the complex and provide protection to polyphenols.Interactions between proteins and polyphenols are largely non-covalent.Factors that affect such interactions include pH,temperature,and the structure of both proteins and polyphenols.Moreover,excellent stability of polyphenols can be achieved by using nanoencapsulation techniques such as emulsion,nanohydrogel,and nanocomplex formation.The use of protein combined with other compounds such as lipids and carbohydrates was found to be the most suitable carrier for polyphenols encapsulation.This review aims to describe the interaction between proteins and polyphenols,focusing on applying nanoencapsulation for increasing stability and targeted delivery of phenolic compounds. | Yun Xiao Talha Ahmad Tarun Belwal Rana Muhammad Aadil Muhammad Siddique Limin Pang Yanqun Xu | 2023 | Food Innovation and Advances2023，2，3： | 0 |
| 5 | Disease Diagnosis System Using IoT Empowered with Fuzzy Inference System显示文摘Disease diagnosis is a challenging task due to a large number of associated factors.Uncertainty in the diagnosis process arises frominaccuracy in patient attributes,missing data,and limitation in the medical expert’s ability to define cause and effect relationships when there are multiple interrelated variables.This paper aims to demonstrate an integrated view of deploying smart disease diagnosis using the Internet of Things(IoT)empowered by the fuzzy inference system(FIS)to diagnose various diseases.The Fuzzy Systemis one of the best systems to diagnose medical conditions because every disease diagnosis involves many uncertainties,and fuzzy logic is the best way to handle uncertainties.Our proposed system differentiates new cases provided symptoms of the disease.Generally,it becomes a time-sensitive task to discriminate symptomatic diseases.The proposed system can track symptoms firmly to diagnose diseases through IoT and FIS smartly and efficiently.Different coefficients have been employed to predict and compute the identified disease’s severity for each sign of disease.This study aims to differentiate and diagnose COVID-19,Typhoid,Malaria,and Pneumonia.This study used the FIS method to figure out the disease over the use of given data related to correlating with input symptoms.MATLAB tool is utilised for the implementation of FIS.Fuzzy procedure on the aforementioned given data presents that affectionate disease can derive from the symptoms.The results of our proposed method proved that FIS could be utilised for the diagnosis of other diseases.This study may assist doctors,patients,medical practitioners,and other healthcare professionals in early diagnosis and better treat diseases. | Talha Mahboob Alam Kamran Shaukat Adel Khelifi Wasim Ahmad Khan Hafiz Muhammad Ehtisham Raza Muhammad Idrees Suhuai Luo Ibrahim A.Hameed | 2022 | Computers, Materials & Continua2022，，3： | 0 |
| 6 | Antifungal, phytotoxic and hemagglutination activity of methanolic extracts of Ocimum basilicum显示文摘OBJECTIVE: To report some of the pharmacological features of the medicinal plant Ocimum basilicum.METHODS: In the current studies, Antifungal activity of crude methanolic fraction of Ocimum basilicum was determined against eight pathogenic fungal strains using tube dilution assay. The methanolic fraction was also investigated for phytotoxic and hemagglutination activity.RESULTS: Of the eight strains investigated only Candida albicans and Curvilaria lunata were found to be least affected by plant extract while the rest were significantly inhibited. Moderate phytotoxic activity was observed against lemna minor. Hemagglutination activity showed absence of phytolectins and hence no agglutination of erythrocytes.CONCLUSION: The crude extract of Ocimum basilicum has significant properties against fungi and phytotoxic substances. | Kafeel Ahmad Ali talha Khalil Yusra Ramla Somayya | 2016 | Journal of Traditional Chinese Medicine2016，36，6： | 0 |
| 7 | Evaluation of antileishmanial,antibacterial and brine shrimp cytotoxic potential of crude methanolic extract of Herb Ocimum basilicum(Lamiacea)显示文摘OBJECTIVE:To collect and screen for ethnopharmacological properties(antileishmanial,antibacterial and brine lethality assays) of medicinal plant Ocimum basilicum from Peshawar region(34.008 latitude and 71.57 altitudes).METHODS:In the present study a general antileishmanial activity against Leishmania tropica strain was carried out.The antibacterial potential of the plant was performed against 06 gram positive and 06 gram negative bacteria.Brine shrimp cytotoxicity assay at different concentrations were investigated.RESULTS:The anti-promastigotes profile of the plant showed good antileishmanial activity exhibited LC_(50) value 21.67 μg/mL.The result for gram positive antibacterial activity revealed that the O.basilicum leaves extract possesses significant inhibitory activity at highest two concentrations ranging from20.66 ± 0.31 to 31.86 ± 0.80 for Clostridium perfringens type C and Bacillus subtitilis,respectively,as compared to the gentamycin(27.36 ± 0.55 and21.80 ± 0.72,respectively).For gram negative bacteria good activity was observed.A highest zone of inhibition was recorded for Pseudomonas aeroginosa(28.83 ± 0.28) atthe highest concentration(10 mg/mL).The LC_(50) value obtained for brine shrimp lethality assay was 91.56 μg/mL.CONCLUSION:The herb basil possesses effective cidal activities which make this plant a good candidate for the isolation of antiprotozoal and antibacterial compounds which may lead to the development of novel drug. | Imran Khan Kafeel Ahmad Ali Talha Khalil Jangrez Khan Yusra Ali Khan Muhammad Shahab Saqib Muhammad Naveed Umar Hilal Ahmad | 2015 | Journal of Traditional Chinese Medicine2015，35，3： | 0 |
| 8 | Response of Contrasting Rice Genotypes to Zinc Sources under Saline Condition显示文摘Abiotic stresses are among the major limiting factors for plant growth and crop productivity.Among these,salinity is one of the major risk factors for plant growth and development in arid to semi-arid regions.Cultivation of salt tolerant crop genotypes is one of the imperative approaches to meet the food demand for increasing population.The current experiment was carried out to access the performance of different rice genotypes under salinity stress and Zinc(Zn)sources.Four rice genotypes were grown in a pot experiment and were exposed to salinity stress(7 dS m^(−1)),and Zn(15 mg kg^(-1)soil)was applied from two sources,ZnSO4 and Zn-EDTA.A control of both salinity and Zn was kept for comparison.Results showed that based on the biomass accumulation and K^(+)/Na^(+)ratio,KSK-133 and BAS-198 emerged as salt tolerant and salt sensitive,respectively.Similarly,based on the Zn concentration,BAS-2000 was reported as Zn-in-efficient while IR-6 was a Zn-efficient genotype.Our results also revealed that plant growth,relative water content(RWC),physiological attributes including chlorophyll contents,ionic concentrations in straw and grains of all rice genotypes were decreased under salinity stress.However,salt tolerant and Zn-in-efficient rice genotypes showed significantly higher shoot K^(+)and Zn concentrations under saline conditions.Zinc application significantly alleviates the harmful effects of salinity by improving morpho-physiological attributes and enhancing antioxidant enzyme activities,and the uptake of K and Zn.The beneficial effect of Zn was more pronounced in salt-tolerant and Zn in-efficient rice genotypes as compared with salt-sensitive and Zn-efficient genotypes.In sum,our results confirmed that Zn application increased overall plant’s performance under saline conditions,particularly in Zn in-efficient and tolerant genotypes as compared with salt-sensitive and Zn efficient rice genotypes. | Muhammad Jan Muhammad Anwar-Ul-Haq Talha Javed Sadam Hussain Ilyas Ahmad Muhammad Ashraf Sumrah Javed Iqbal Babar Hussain Babar Aqsa Hafeez Muhammad Aslam Muhammad Tahir Akbar Marjan Aziz Khadiga Alharbi Izhar Ullah | 2023 | Phyton-International Journal of Experimental Botany2023，92，5： | 0 |
| 9 | A low complexity online controller using fuzzy logic in energy harvesting WSNs显示文摘In this paper, we present a fuzzy logic based scheme for a two hop energy harvesting(EH)wireless sensor network(WSN). Incorporating data and energy causality constraints, discrete transmission rates, finite energy and data buffers, a fuzzy model is developed which uses network throughput, battery level and channel gain as inputs. The fuzzy scheme is then compared with optimum, modified optimum, and Markov decision process(MDP) schemes in terms of computational complexity, throughput, battery level and data buffer capacity. The throughput results show that the fuzzy online scheme preforms closely to the compared schemes and avoids battery depletion even when the number of discrete transmission rates are increased. | Talha AZFAR Waqas AHMED Abdul HASEEB Rizwan AHMAD Sufi Tabassum GUL Fu-Chun ZHENG | 2019 | Science China(Information Sciences)2019，62，4： | 0 |
| 10 | A Quantum Spatial Graph Convolutional Network for Text Classification显示文摘The data generated from non-Euclidean domains and its graphical representation(with complex-relationship object interdependence)applications has observed an exponential growth.The sophistication of graph data has posed consequential obstacles to the existing machine learning algorithms.In this study,we have considered a revamped version of a semi-supervised learning algorithm for graph-structured data to address the issue of expanding deep learning approaches to represent the graph data.Additionally,the quantum information theory has been applied through Graph Neural Networks(GNNs)to generate Riemannian metrics in closed-form of several graph layers.In further,to pre-process the adjacency matrix of graphs,a new formulation is established to incorporate high order proximities.The proposed scheme has shown outstanding improvements to overcome the deficiencies in Graph Convolutional Network(GCN),particularly,the information loss and imprecise information representation with acceptable computational overhead.Moreover,the proposed Quantum Graph Convolutional Network(QGCN)has significantly strengthened the GCN on semi-supervised node classification tasks.In parallel,it expands the generalization process with a significant difference by making small random perturbationsG of the graph during the training process.The evaluation results are provided on three benchmark datasets,including Citeseer,Cora,and PubMed,that distinctly delineate the superiority of the proposed model in terms of computational accuracy against state-of-the-art GCN and three other methods based on the same algorithms in the existing literature. | Syed Mustajar Ahmad Shah Hongwei Ge Sami Ahmed Haider Muhammad Irshad Sohail M.Noman Jehangir Arshad Asfandeyar Ahmad Talha Younas | 2021 | Computer Systems Science & Engineering2021，36，2： | 0 |
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