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| 1 | Endoscopic ultrasound-guided fine needle aspiration in the differentiation of type 1 and type 2 autoimmune pancreatitis显示文摘AIM:To investigate the usefulness of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) in the differentiation of autoimmune pancreatitis(AIP).METHODS:We retrospectively reviewed 47 of 56 AIP patients who underwent EUS-FNA and met the Asian diagnostic criteria.On 47 EUS-FNA specimens,we evaluated the presence of adequate material and characteristic features of lymphoplasmacytic sclerosing pancreatitis(LPSP) and idiopathic duct-centric pancreatitis(IDCP) mentioned in the International Consensus Diagnostic Criteria and examined if these findings make a contribution to the differential diagnosis of type 1 and type 2 AIP.A disposable 22-gauge needle was used for EUS-FNA.RESULTS:Adequate specimens including pancreatic tissue for differentiating AIP from cancer were obtained from 43 of 47 patients who underwent EUSFNA.EUS-FNA was performed from the pancreatic head in 21 cases,which is known to be technically difficult when performed by core biopsy;there was no significant difference in the results compared with pancreatic body-tail.Nine of 47 patients met level 1 findings of LPSP and 5 patients met level 2 findings of LPSP.No one met level 1 findings of IDCP,but 3 patients met level 2 findings of IDCP.Of 10 seronegative cases,2 cases were diagnosed with 'definitive type 1 AIP',and 3 cases were diagnosed with 'probable type 2 AIP' when considering both the level 2 histological findings and response to steroids.CONCLUSION:EUS-FNA is useful in the differentiation of type 1 and type 2 AIP,particularly in seronegative cases. | Takuya Ishikawa Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Hirosh Matsubara Yuya Itoh Yosuke Nakamura Takeshi Hiramatsu Masanao Nakamura Ryoji Miyahara Naoki Ohmiya Hidemi Goto Yoshiki Hirooka | 2012 | World Journal of Gastroenterology2012，18，29： | 8 |
| 2 | Contrast-enhanced endoscopic ultrasonography in digestive diseases显示文摘 | Yoshiki Hirooka Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Yuya Itoh Yosuke Nakamura Takeshi Hiramatsu Hiroyuki Sugimoto Hajime Sumi Daijiro Hayashi Naoki Ohmiya Ryoji Miyahara Masanao Nakamura Kohei Funasaka Masatoshi Ishigami Yoshiaki Katano Hidemi Got | 2012 | Journal of Gastroenterology2012，，10： | 2 |
| 3 | Contrast-enhanced endoscopic ultrasonography in digestive diseases显示文摘 | Yoshiki Hirooka Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Yuya Itoh Yosuke Nakamura Takeshi Hiramatsu Hiroyuki Sugimoto Hajime Sumi Daijiro Hayashi Naoki Ohmiya Ryoji Miyahara Masanao Nakamura Kohei Funasaka Masatoshi Ishigami Yoshiaki Katano Hidemi Got | 2012 | Journal of Gastroenterology2012，，10： | 2 |
| 4 | Maximum standardized lymph node uptake value could be an important predictor of recurrence and survival in patients with cervical cancer显示文摘 | Keiichiro Nakamura Ikuo Joja Takeshi Nagasaka Tomoko Haruma Yuji Hiramatsu | 2014 | European Journal of Obstetrics and Gynecology2014，，： | 1 |
| 5 | Peripancreatic vascular involvements of autoimmune pancreatitis显示文摘 | Takuya Ishikawa Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Yuya Itoh Yosuke Nakamura Takeshi Hiramatsu Ryoji Miyahara Naoki Ohmiya Jyunichi Haruta Hidemi Goto Yoshiki Hirooka | 2012 | J Gastroenterol Hepatol2012，，12： | 1 |
| 6 | Surgical Results for Functional Univentricular Heart With Total Anomalous Pulmonary Venous Connection Over a 25-Year Experience显示文摘 | Yuki Nakayama Takeshi Hiramatsu Yusuke Iwata Toru Okamura Takeshi Konuma Goki Matsumura Kenji Suzuki Kyoko Hobo Toshio Nakanishi Hiromi Kurosawa Kenji Yamazaki | 2012 | The Annals of Thoracic Surgery2012，，2： | 1 |
| 7 | Mesenteric paraganglioma: Report of a case显示文摘We report a rare case of paraganglioma that developed in the mesentery of terminal ileum. A 78-year-old woman complained of right-sided abdominal pain. Abdominal computed tomography revealed a solid heterogeneously enhanced mass in the right lower abdomen. The tumor was laparoscopically excised. The mesenteric tumor was well circumscribed, ovoid, and encapsulated and measured 3 cm × 1.5 cm × 1.5 cm. Histological examination showed a cellular neoplasm comprised of nests and groups of tumor cells separated by fibrovascular connective tissue, giving a characteristic nested Zellballen pattern. Immunohistochemically, the tumor cells were positive for chromogranin, synaptophysin, CD56, and vimentin and negative for cytokeratins, SMA, CD34, CD117/c-kit and S100. On the basis of histologic and immunohistochemical features, a diagnosis of mesenteric paraganglioma was made. The operative and postoperative courses were unremarkable, and the patient was discharged on postoperative day 7. She was doing well 1 year after the surgery with no signs of recurrence. Extra-adrenal paragangliomas most commonly develop adjacent to the aorta, particularly the area corresponding to the organ of Zuckerkandl. Mesenteric paraganglioma, as in our case, is extremely rare; only 11 cases have been reported in the literature. We herein discuss the clinical findings of these cases. | Takeshi Fujita Kinji Kamiya Yoshiaki Takahashi Shinichiro Miyazaki Ichirota Iino Hirotoshi Kikuchi Yoshihiro Hiramatsu Manabu Ohta Satoshi Baba Hiroyuki Konno | 2013 | World Journal of Gastrointestinal Surgery2013，5，3： | 1 |
| 8 | Clinical oncology for pancreatic and biliary cancers:Advances and current limitations显示文摘In the early 2000s,the main stream of endoscopic ultrasonography(EUS)changed from a mechanical scanning method to electronic radial or linear scanning methods.Subsequently,useful applications in trans-abdominal ultrasonography came within reach of EUS.In particular,contrast-enhanced EUS(CE-EUS)and EUS-elastography became cutting-edge diagnostic modalities for pancreatic disorders.Each type of pancreatic disorder has characteristic hemodynamics.CE-EUS uses color Doppler flow imaging and harmonic imaging to classify pancreatic lesions.EUS-elastography can assess tissue hardness by measuring its elasticity.This parameter appears to correlate with the malignant potential of the lesions.Tissue elasticity studies can provide information on both its pattern and distribution.The former is the conventional method of morphological diagnosis,but it is restricted to observations made in a region of interest(ROI).The latter is an unbiased analysis that can be performed by image analysis software and is theoretically constant,regardless of the ROI.Though EUSfine needle aspiration(FNA)is also a very useful diagnostic tool,there are several limitations.Diagnostic EUS-FNA of pancreatic cystic lesions has marginal utility mainly due to low sensitivity.Therefore,in particular,endoscopists should keep this limitation in mind. | Yoshiki Hirooka Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Takuya Ishikawa Yuya Itoh Yosuke Nakamura Takeshi Hiramatsu Masanao Nakamura Ryoji Miyahara Naoki Ohmiya Masatoshi Ishigami Yoshiaki Katano Hidemi Goto | 2011 | World Journal of Clinical Oncology2011，2，5： | 1 |
| 9 | ASCL1-coexpression profiling but not single gene expression profiling defines lung adenocarcinomas of neuroendocrine nature with poor prognosis显示文摘 | Takeshi Fujiwara Miyako Hiramatsu Takayuki Isagawa Hironori Ninomiya Kentaro Inamura Shumpei Ishikawa Masaru Ushijima Masaaki Matsuura Michael H. Jones Miyuki Shimane Hitoshi Nomura Yuichi Ishikawa Hiroyuki Aburatani | 2011 | Lung Cancer2011，，1： | 1 |
| 10 | A neutral proteinase from Streptoinyees naraensis(III):An Improved purification and some physicochemical properties显示文摘 | Akira Hiramatsu Takeshi Ouchi | | 0，，： | 1 |
| 11 | Zinc of neutral proteinase from Streptomyces naraensis显示文摘 | Akira Hiramatsu Takeshi Ouchi | | 0，，7： | 1 |
| 12 | Evidence for essential histidine residue in neutral proteinase from Streptomyces naraensis显示文摘 | Akira Hiramatsu Yoshihisa Suzuki Takeshi Ouchi | | 0，，2： | 1 |
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