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38篇 您的检索式:作者名="Siuzdak"
    题名 作者 年代 出处 被引量
1The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming显示文摘新陈代谢对房间功能的每个方面重要,然而,导致的 pluripotent 干细胞(iPSCs ) 的 metabolome 仍然保持大部分未经勘探。这里,我们报导,用一条 untargeted metabolomics 途径,那人的 iPSCs 份额有从他们的父母房间是不同的胚胎的干细胞(转换字符) 的 pluripotent metabolomic 签名,并且那被变化在涉及细胞的呼吸的代谢物描绘。细胞的 bioenergetics 的检查与我们的 metabolomic 分析支持了,并且证明体的房间在 pluripotency 从一个氧化状态变换成一个 glycolytic 状态。有趣地,各种各样的体的房间的 bioenergetics 与他们的 reprogramming 效率相关。我们进一步识别了在 iPSCs 和转换字符之间不同的代谢物,它揭示了在调整体的房间 reprogramming 起一个关键作用的新奇新陈代谢的小径。我们的调查结果是第一全球性分析 iPSCs 的 metabolome,并且提供机械学的卓见进涉及导致 pluripotency,并且在评估 iPSC 和转换字符等价的规定的新层。Athanasia D Panopoulos Oscar Yanes Sergio Ruiz Yasuyuki S Kida Dinh Diep Ralf Tautenhahn Aida Herrerias Erika M Batchelder Nongluk Plongthongkum Margaret Lutz W Travis Berggren Kun Zhang Ronald M Evans Gary Siuzdak Juan Carlos Izpisua Belmonte] 2012Cell Research2012,22,1:12
2Desorption-ionization mass spectrometry on porous silicon 显示文摘WEI J BURIAK J M SIUZDAK G 1999Nature1999,399,:1
3XCMS Online: a web-based platform to process untargeted metabolomic data 显示文摘Tautenhahn R Patti GJ Rinehart D Siuzdak G 2012Anal Chem2012,84,11:1
4A Single Filter for Edge Detection显示文摘SIUZDAK J 1998Pattern Recognition1998,31,:1
5The emergence of mass spectrometry in biochemical research显示文摘 1994Proc Natl Acad Sci USA1994,91,11:1
6Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins显示文摘Hongyan Zhou Shili Wu Jin Young Joo Saiyong Zhu Dong Wook Han Tongxiang Lin Sunia Trauger Geoffery Bien Susan Yao Yong Zhu Gary Siuzdak Hans R. Sch?ler Lingxun Duan Sheng Ding 2009Cell Stem Cell2009,,5:1
7Mass spectrometry in viral proteomics显示文摘THOMAS J J BAKHTIAR R SIUZDAK G 2000Acc Chem Res2000,3,3:1
8Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins显示文摘Hongyan Zhou Shili Wu Jin Young Joo Saiyong Zhu Dong Wook Han Tongxiang Lin Sunia Trauger Geoffery Bien Susan Yao Yong Zhu Gary Siuzdak Hans R. Sch?ler Lingxun Duan Sheng Ding 2009Cell Stem Cell2009,,5:1
9Peptide and protein analysis with mass spectrometry显示文摘Sunia A. Trauger William Webb Gary Siuzdak 2002Spectroscopy2002,,1:1
10显示文摘SIUZDAK G 1994Proc Natl Acad Sci USA1994,91,11:1
11显示文摘Siuzdak D A Mauritz K A 1999J Polym Sci Part B: Polym Phys1999,37,:1
12Electrospray and MALDI mass spectrometry in the identification of spermicides in criminal investigations显示文摘Hollenbeck TP Siuzdak G Blackledge RD 1999J Forensic Sci1999,44,4:1
13Mass spectrometry and viral analysis显示文摘Siuzdak G Bothner B Yeager M 1996Chem Biol1996,3,1:1
14Innovation: Metabolomics: the apogee of the omics trilogy显示文摘Patti G J Yanes O Siuzdak G 2012Nat Rev Mol Cell Biol2012,13,4:1
15Desorption-ionization mass spectrometry on porous silicon 显示文摘Wei J Buriak J M Siuzdak G 1999Nature1999,399,6733:1
16Compensation of a VLC phosphorescent white LED nonlinearity by means of Voherra DFE 显示文摘Stepniak G Siuzdak J Zwierko P 2011IEEE Photonics Technology Letters2011,25,16:1
17Peptide and protein analysis with mass spectrometry显示文摘Trauger SA Webb W Siuzdak G 2002Spectroscopy2002,16,1:1
18Compensation of a VLC phosphorescent white LED nonlinearity by means ofVolterra DFE 显示文摘Stepniak G Siuzdak J Zwierko P 2011IEEE Photonics Technology Letters2011,25,16:1
19The expanding role of mass spectrometry in metabolite profiling and characterization 显示文摘Want E J Cravatt B F Siuzdak G 2005ChemBioChem2005,6,11:1
20Compensation of a VLC phosphorescent white LED nonlinearity by means of Volterra DFE显示文摘Stepniak G Siuzdak J Zwierko P 2011IEEE Photonics Technology Letters2011,25,16:1
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