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| 1 | 新型吸入麻醉剂-七氟醚的研究进展II.兽医药效学显示文摘新型吸入麻醉剂七氟醚在犬、猫、马、鼠的 MAC分别为 2 .1 0~ 2 .36 ,2 .5 8,2 .31 ,2 .40~ 2 .5 0 Vol%。像异氟醚那样 ,七氟醚可降低脑血管阻力、脑代谢率、脑耗氧量、心肌收缩功能和血压。七氟醚可引起猫惊厥。虽然猪的心跳在七氟醚麻醉下维持稳定 ,但研究表明犬的心率则升高。七氟醚麻醉下引起心律失常的肾上腺素剂量与异氟醚相似 ,但大大高于氟烷或安氟醚。七氟醚对呼吸道的刺激性明显低于其他吸入麻醉剂。尚未见其肝肾毒性。 | 熊惠军 Sabine Tacke Ernst Schimke | 2001 | 动物医学进展2001，22，2： | 3 |
| 2 | 七氟醚 氟烷 异氟醚对犬心脏功能影响的临床比较显示文摘为评价七氟醚对心脏功能的影响 ,并与氟烷和异氟醚作比较 ,对动物医院就诊、心肺功能正常、拟作手术治疗的 86例患犬进行麻醉试验。所有犬均以 l-美散痛和安定作为麻醉前给药。分别以 1.5 %七氟醚、1.0 %七氟醚与 6 6 .7%笑气、1.0 %氟烷、1.5 %异氟醚维持手术麻醉 ,并作人工呼吸。各组均未观察到心律异常。手术麻醉期间 ,七氟醚组犬心率降幅 (4 .73% )低于异氟醚组 (9.74% )或氟烷组 (10 .2 3% )。七氟醚组、氟烷组和异氟醚组的收缩压 /舒张压轻度升高 (七氟醚 3.38% / 11.93% ,氟烷 6 .0 9% / 9.0 9% ,异氟醚 4.82 % / 6 .2 5 % )。而七氟醚与笑气组的收缩压 /舒张压则降低 (6 .84% / 5 .73% )。 | 熊惠军 Sabine Tacke Ernst Schimke | 2001 | 中国兽医杂志2001，37，5： | 3 |
| 3 | Beta-7 integrin controls enterocyte migration in the small intestine显示文摘AIM:To hypothesize that beta-7 integrin affects cellularmigration of both,lymphocytes and enterocytes.METHODS:The nucleoside analog Brd U was ip injected in beta-7-deficient mice(C57BL/6-Itgbtmlcgn/J)of male gender and age-matched male C57BL/J J mice(wild type)4,20,or 40 h before analysis.The total small intestine was isolated,dissected,and used for morphometrical studies.Brd U-positive epithelial cells were numbered in at least 15 hemi-crypts per duodenum,jejunum,and ileum of each animal.The outer most Brd U-positive cell(cellmax)was determined per hemi-crypt,numerically documented,and statistically analysed.RESULTS:Integrins containing the beta-7-chain were exclusively expressed on leukocytes.In the small intestinal mucosa of beta-7 integrin-deficient mice the number of intraepithelial lymphocytes was drastically decreased.Moreover,the Peyer’s patches of beta-7integrin-deficient mice appeared hypoplastic.In beta-7integrin-deficient mice the location of cellmax was found in a higher position than it was the case for the controls.The difference was already detected at 4 h after Brd U application,but significantly increased with time(40 h after Brd U injection)in all small intestinal segments investigated,i.e.,duodenum,jejunum,and ileum.Migration of small intestinal enterocytes was different between the experimental groups measured by cellmax locations.CONCLUSION:The E-cadherin beta-7 integrin pathway probably controls migration of enterocytes within the small intestinal surface lining epithelial layer. | Elke Kaemmerer Paula Kuhn Ursula Schneider Thomas Clahsen Min Kyung Jeon Christina Klaus Julia Andruszkow Michael Hrer Sabine Ernst Angela Schippers Norbert Wagner Nikolaus Gassler | 2015 | World Journal of Gastroenterology2015，21，6： | 3 |
| 4 | 犬七氟醚 氟烷 异氟醚麻醉后的苏醒时间和苏醒特点的临床比较显示文摘 | 熊惠军 TACKE Sabine SCHIMKE Ernst | 2001 | 中国兽医杂志2001，37，7： | 2 |
| 5 | Initial Experience With Remote Catheter Ablation Using a Novel Magnetic Navigation System Magnetic Remote Catheter Ablation显示文摘 | Sabine Ernst Feifan Ouyang Christian Linder | 2004 | Circulation2004，109，12： | 1 |
| 6 | The Helicobacter pylori plasticity region locus jhp0947–jhp0949 is associated with duodenal ulcer disease and interleukin-12 production in monocyte cells显示文摘 | Ramon de Jonge Ernst J. Kuipers Sabine C.L. Langeveld Ruud J.L.F. Loffeld Jeroen Stoof Arnoud H.M. van Vliet Johannes G. Kusters | 2004 | FEMS Immunology and Medical Microbiology2004，，2： | 1 |
| 7 | Superlubricity of dry nano- contacts显示文摘 | Enrico G Sabine M Ernst M | 2008 | Journal of Physics: Condensed Matter2008，20，35： | 1 |
| 8 | Docetaxel monotherapy in heavily pretreated metastatic breast cancer: a multicenter, community-based feasibility trial显示文摘 | Manuela Schmidinger Alexandra C. Budinsky Catharina Wenzel Gottfried J. Locker Ursula Pluschnig Thomas Brodowicz Ernst Kubista Sylvia Maca August Zabernigg Peter Ilsinger Lothar Seewann Sabine Hojas Michaela Blach Christoph C. Zielinski Guenther G. Steger | 2000 | Cancer Chemotherapy and Pharmacology2000，，1： | 1 |
| 9 | Crosstalk and differential response to abiotic and biotic stressors reflected at the transcriptional level of effector genes from secondary metabolism显示文摘 | Sabine Glombitza Pierre-henri Dubuis Oliver Thulke Gerhard Welzl Lucien Bovet Michael G?tz Matthias Affenzeller Birgit Geist Alain Hehn Carole Asnaghi Dieter Ernst Harald Seidlitz Heidrun Gundlach Klaus Mayer Enrico Martinoia Daniele Werck-reichhart Felix | 2004 | Plant Molecular Biology2004，，6： | 1 |
| 10 | Autoimmune hepatitis after high-dose intravenous methylprednisolone pulse in RR-MS显示文摘 | Reinhard Reu? Kerstin Retzlaff Sabine Vogel Folker Ernst Franke Patrick Oschmann | 2007 | Central European Journal of Medicine2007，，3： | 1 |
| 11 | Recovered Pulmonary Vein Conduction as a Dominant Factor for Recurrent Atrial Tachyarrhythmias After Complete Circular Isolation of the Pulmonary Veins: Lessons From Double Lasso Technique显示文摘 | Feifan Ouyang Matthias Antz Sabine Ernst Hitoshi Hachiya Hercules Mavrakis Florian T. Deger Anselm Schaumann Julian Chun Peter Falk Detlef Hennig Xingpeng Liu Dietmar B?nsch Karl-Heinz Kuck | 2005 | Circulation2005，，2： | 1 |
| 12 | Crosstalk and differential response to abiotic and biotic stressors reflected at the transcriptional level of effector genes from secondary metabolism显示文摘 | Sabine Glombitza Pierre-henri Dubuis Oliver Thulke Gerhard Welzl Lucien Bovet Michael G?tz Matthias Affenzeller Birgit Geist Alain Hehn Carole Asnaghi Dieter Ernst Harald Seidlitz Heidrun Gundlach Klaus Mayer Enrico Martinoia Daniele Werck-reichhart Felix | 2004 | Plant Molecular Biology2004，，6： | 1 |
| 13 | 七氟醚、氟烷、异氟醚对犬肝肾功能影响的临床比较显示文摘为评价七氟醚对肝肾功能的影响 ,并与氟烷和异氟醚作比较 ,对动物医院就诊的心肺功能正常 ,拟作手术治疗的 6 1头患犬进行麻醉试验。所有犬均以l 美散痛和安定作为麻醉前给药。分别以 1 5 %七氟醚、1 0 %氟烷、1 5 %异氟醚维持手术麻醉。所有 3组中无一组可见肝肾毒性副作用。至七氟醚麻醉后 48h ,GLDH ,AST ,ALT ,γ GT ,总胆红素 ,AP ,尿素氮和肌酐显示正常。 | 熊惠军 Sabine Tacke Ernst Schimke | 2002 | 畜牧兽医学报2002，33，5： | 1 |
| 14 | Complete Isolation of Left Atrium Surrounding the Pulmonary Veins: New Insights From the Double-Lasso Technique in Paroxysmal Atrial Fibrillation显示文摘 | Feifan Ouyang Dietmar B?nsch Sabine Ernst Anselm Schaumann Hitoshi Hachiya Minglong Chen Julian Chun Peter Falk Afsaneh Khanedani Matthias Antz Karl-Heinz Kuck | 2004 | Circulation2004，，15： | 1 |
| 15 | Modification of the Substrate for Maintenance of Idiopathic Human Atrial Fibrillation: Efficacy of Radiofrequency Ablation Using Nonfluoroscopic Catheter Guidance显示文摘 | Sabine Ernst Michael Schlüter Feifan Ouyang Afsaneh Khanedani Riccardo Cappato Joachim Hebe Marius Volkmer Matthias Antz Karl-Heinz Kuck | 1999 | Circulation1999，，20： | 1 |
| 16 | Electroanatomic Substrate of Idiopathic Left Ventricular Tachycardia: Unidirectional Block and Macroreentry Within the Purkinje Network显示文摘 | Feifan Ouyang Riccardo Cappato Sabine Ernst Masahiko Goya Marius Volkmer Joachim Hebe Matthias Antz Thomas Vogtmann Anselm Schaumann Parwis Fotuhi Martin Hoffmann-Riem Karl-Heinz Kuck | 2002 | Circulation: Journal of the American Heart Association2002，，4： | 1 |
| 17 | Initial Experience With Remote Catheter Ablation Using a Novel Magnetic Navigation System Magnetic Remote Catheter Ablation 显示文摘 | Sabine Ernst Feifan Ouyang Christian Linder | 2004 | Circulation2004，109，12： | 1 |
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