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| 1 | Interrelationship between chromosome 8 aneuploidy,C-MYC amplification and increased expression in individuals from northern Brazil with gastric adenocarcinoma显示文摘AIM: To investigate chromosome 8 numerical aberra- tions, C-MYC oncogene alterations and its expression in gastric cancer and to correlate these findings with histo- pathological characteristics of gastric tumors. METHODS: Specimens were collected surgically from seven patients with gastric adenocarcinomas. Immu- nostaining for C-MYC and dual-color fluorescence in situ hybridization (FISH) for C-MYC gene and chromosome 8 centromere were performed. RESULTS: All the cases showed chromosome 8 aneu- ploidy and C-MYC amplification, in both the diffuse and intestinal histopathological types of Lauren. No significant difference (P < 0.05) was observed between the level ofchromosome 8 ploidy and the site, stage or histological type of the adenocarcinomas. C-MYC high amplification, like homogeneously stained regions (HSRs) and double minutes (DMs), was observed only in the intestinal-type. Structural rearrangement of C-MYC, like translocation, was observed only in the diffuse type. Regarding C-MYC gene, a significant difference (P < 0.05) was observed between the two histological types. The C-MYC protein was expressed in all the studied cases. In the intestinal- type the C-MYC immunoreactivity was localized only in the nucleus and in the diffuse type in the nucleus and cytoplasm. CONCLUSION: Distinct patterns of alterations between intestinal and diffuse types of gastric tumors support the hypothesis that these types follow different genetic path- ways. | Danielle Queiroz Calcagno Mariana Ferreira Leal Aline Damaceno Seabra Andre Salim Khayat Elizabeth Suchi Chen Samia Demachki Paulo Pimentel Assumpcao Mario Henrique Girao Faria Silvia Helena Barem Rabenhorst Márcia Valéria Pitombeira Ferreira Marília de Arruda Cardoso Smith Rommel Rodríguez Burbano | 2006 | World Journal of Gastroenterology2006，12，38： | 9 |
| 2 | Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design显示文摘 | Marta Burrel María Reig Alejandro Forner Marta Barrufet Carlos Rodríguez de Lope Silvia Tremosini Carmen Ayuso Josep M Llovet María Isabel Real Jordi Bruix | 2012 | Journal of Hepatology2012，，6： | 3 |
| 3 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 4 | A critical evaluation of flurescence as a potential marker for the Maillard reation显示文摘 | Silvia B Matiacevich M Pilar B | 2006 | Food Chemistry2006，95，： | 1 |
| 5 | Identification and determination of metabolites and degradation products of sulfonamide antibiotics显示文摘 | Garcia-Galan Jesus M Diaz-Cruz Silvia M Barcelo Damia | 2008 | Trends in Analytical Chemistry2008，27，11： | 1 |
| 6 | Liquid crystalline ionic dendrimer scontaining luminescent oxadiazole moieties显示文摘 | Silvia H A Barber J Marcos M | 2012 | Maeromole- cules2012，45，2： | 1 |
| 7 | Polymers containing quaternary ammonium groups based on poly ( N- vinylimidazole) 显示文摘 | CORNELIA L SILVIA M MARCEL P | 2002 | European Polymer Journal2002，38，8： | 1 |
| 8 | Survival of patients with hepatocellular carcinoma treated by transarterial chemoembolisation (TACE) using Drug Eluting Beads. Implications for clinical practice and trial design显示文摘 | Marta Burrel María Reig Alejandro Forner Marta Barrufet Carlos Rodríguez de Lope Silvia Tremosini Carmen Ayuso Josep M Llovet María Isabel Real Jordi Bruix | 2012 | Journal of Hepatology2012，，6： | 1 |
| 9 | Subclasses of starlike functions subordinate to convex functions显示文摘 | SILVERMAN H SILVIA E M | 1985 | Canadian Journal of Mathematics1985，37，1： | 1 |
| 10 | Rice bran oil,not fiber,lowers cholesterol in humans显示文摘 | Marlene M Most Richard Tulley Silvia Morales | 2005 | American Journal of Clinical Nutrition2005，1，： | 1 |
| 11 | Manipulation of Strawberry Fruit Softening by Antisense Expression of a Pectate Lyase gene显示文摘 | SILVIA J B JOSE R N JUAN M B | 2002 | Plant Physiol2002，，128： | 1 |
| 12 | Brassica juncea can improve selenite and selenate abatement in selenium contaminated soil through the aid of its rhizospheric bacterial population显示文摘 | Simona D G Silvia L Fernando M | 2006 | Plant Soil2006，285，： | 1 |
| 13 | Identification of a Vacuolar Sucrose Transporter in Barley and Arabidopsis Meso- phyll cells by a Tonoplast Proteomic Approach显示文摘 | ANNE E STEFAN M SILVIA S | 2006 | American So- ciety of Plant Biologists2006，141，1： | 1 |
| 14 | Differences in the pheno- lic composition and sensory profile between red wines aged in oak barrels and wines aged with oak chips显示文摘 | Miriam O H Silvia P M Estela C M | 2010 | LWT-Food Science and Technology2010，，43： | 1 |
| 15 | Neurological mechanisms of green tea polyphenols inAlzheimer's and Parkinson's diseases显示文摘 | Orly W Silvia M Tamar A | 2004 | J Nutri Biochem2004，15，： | 1 |
| 16 | Remotely operated vehicle depth control显示文摘 | Zanoli Silvia M Conte Giuseppe | 2003 | Control Engineering Practice2003，，11： | 1 |
| 17 | Eleetronie noses for food quality: A review 显示文摘 | Amy L Silvia C Ganesh K M | 2015 | Journal of Food Engineering2015，144，： | 1 |
| 18 | Determination of antimicrobials in sludge from infiltration basins at two artificial recharge plants by pressurized liquid extraction-liquid chromatography-tandem mass spectrometry显示文摘 | SILVIA DIAZ-CRUZ M JOSE LOPEZ DE ALDA M BARCELO D | 2006 | J Chromatogr:A2006，1130，1： | 1 |
| 19 | Interaction of bovine serum albumin with gemini surfactants 显示文摘 | SILVIA T ADALBERTO B CAMILLO L M | 2010 | Journal of Colloid and Interface Science2010，347，1： | 1 |
| 20 | Effect of Pfaffia paniculata (Brazilian ginseng)on the Ehrlich tumor in its ascetic form显示文摘 | Patricia M Gokithi A Silvia C S O | 2003 | Life Sci2003，74，： | 1 |
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