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| 1 | Transcranial Doppler ultrasonography: From methodology to major clinical applications显示文摘Non-invasive Doppler ultrasonographic study of cerebral arteries [transcranial Doppler(TCD)] has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency(≤ 2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays the most widespread indication for TCD in outpatient setting is the research of right to left shunting, responsable of so called 'paradoxical embolism', most often due to patency of foramen ovale which is responsable of the majority of cryptogenic strokes occuring in patients younger than 55 years old. TCD also allows to classify the grade of severity of such shunts using the so called 'microembolic signal grading score'. In addition TCD has found many useful applications in neurocritical care practice. It is useful on both adults and children for day-to-day bedside assessment of critical conditions including vasospasm in subarachnoidal haemorrhage(caused by aneurysm rupture or traumatic injury), traumatic brain injury, brain stem death. It is used also to evaluate cerebral hemodynamic changes after stroke. It also allows to investigate cerebral pressure autoregulation and for the clinical evaluation of cerebral autoregulatory reserve. | Antonello D'Andrea Marianna Conte Massimo Cavallaro Raffaella Scarafile Lucia Riegler Rosangela Cocchia Enrica Pezzullo Andreina Carbone Francesco Natale Giuseppe Santoro Pio Caso Maria Giovanna Russo Eduardo Bossone Raffaele Calabrò | 2016 | World Journal of Cardiology2016，8，7： | 10 |
| 2 | Remotely operated vehicle depth control显示文摘 | Zanoli Silvia M Conte Giuseppe | 2003 | Control Engineering Practice2003，，11： | 1 |
| 3 | Robust Control of a Remotely Operated Underwater Vehicle显示文摘 | Giuseppe Conte Andrea Serrani | 1998 | Automatica1998，34，2： | 1 |
| 4 | Remotely operated vehicle depth control显示文摘 | Silvia M Zanoli Giuseppe Conte | 2003 | Control Engineering Practice2003，11，： | 1 |
| 5 | Treatment of mild non-chemotherapy-induced iron deficiency anemia in cancer patients: Comparison between oral ferrous bisglycinate chelate and ferrous sulfate显示文摘 | Paola Ferrari Andrea Nicolini Maria Laura Manca Giuseppe Rossi Loretta Anselmi Massimo Conte Angelo Carpi Ferruccio Bonino | 2012 | Biomedicine & Pharmacotherapy2012，，6： | 1 |
| 6 | Inflammation and Cardiovascular Disease: From Pathogenesis to Therapeutic Target显示文摘 | Enrica Golia Giuseppe Limongelli Francesco Natale Fabio Fimiani Valeria Maddaloni Ivana Pariggiano Renatomaria Bianchi Mario Crisci Ludovica D’Acierno Roberto Giordano Gaetano Palma Marianna Conte Paolo Golino Maria Giovanna Russo Raffaele Calabrò Paolo C | 2014 | Current Atherosclerosis Reports2014，，9： | 1 |
| 7 | On the development of the coronary arteries in human embryos, stages 14–19显示文摘 | Giuseppe Conte Antonio Pellegrini | 1984 | Anatomy and Embryology1984，，： | 1 |
| 8 | Cystatin C is associated with an increased coronary atherosclerotic burden and a stable plaque phenotype in patients with ischemic heart disease and normal glomerular filtration rate显示文摘 | Giampaolo Niccoli Micaela Conte Roberta Della Bona Luca Altamura Massimo Siviglia Ilaria Dato Giuseppe Ferrante Antonio M. Leone Italo Porto Francesco Burzotta Salvatore Brugaletta Luigi M. Biasucci Filippo Crea | 2007 | Atherosclerosis2007，，2： | 1 |
| 9 | Autoimmune epilepsy显示文摘 | Antonio Greco Maria Ida Rizzo Armando De Virgilio Michela Conte Andrea Gallo Giuseppe Attanasio Giovanni Ruoppolo Marco de Vincentiis | 2015 | Autoimmunity Reviews2015，，： | 1 |
| 10 | Coronary atherosclerotic burden in patients with infection by CagA-positive strains of Helicobacter pylori显示文摘 | Giampaolo Niccoli Francesco Franceschi Nicola Cosentino Bianca Giupponi Guido De Marco Giuseppe Merra Micaela Conte Rocco Antonio Montone Giuseppe Ferrante Marco Bacà Antonio Gasbarrini Nicolò Gentiloni Silveri Filippo Crea | 2010 | Coronary Artery Disease2010，，4： | 1 |
| 11 | CagA antigen of helicobacter pylori and coronary instability: Insight from a clinico-pathological study and a meta-analysis of 4241 cases显示文摘 | Francesco Franceschi Giampaolo Niccoli Giuseppe Ferrante Antonio Gasbarrini Alfonso Baldi Marcello Candelli Florinda Feroce Nathalie Saulnier Micaela Conte Davide Roccarina Gaetano A. Lanza Giovanni Gasbarrini Silveri Nicolò Gentiloni Filippo Crea | 2008 | Atherosclerosis2008，，2： | 1 |
| 12 | Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma: Characterization in a 3D-cell culture model显示文摘AIM: To analyze the effect of three-dimensional(3D)-arrangement on the expression of epithelial-tomesenchymal transition markers in pancreatic adenocarcinoma(PDAC) cells.METHODS: HPAF-Ⅱ, HPAC, and PL45 PDAC cells were cultured in either 2D-monolayers or 3D-spheroids. Ultrastructure was analyzed by transmission electron microscopy. The expression of E-cadherin, β-catenin, N-cadherin, collagen type Ⅰ(COL-I), vimentin, α-smooth muscle actin(αSMA), and podoplanin was assayed by confocal microscopy in cells cultured on 12-mm diameter round coverslips and in 3D-spheroids. Gene expression for E-cadherin, Snail, Slug, Twist, Zeb1, and Zeb2 was quantified by real-time PCR. E-cadherin protein level and its electrophoretic pattern were studied by Western blot in cell lysates obtained from cells grown in 2D-monolayers and 3D-spheroids. RESULTS: The E-cadherin/β-catenin complex was expressed in a similar way in plasma membrane cell boundaries in both 2D-monolayers and 3D-spheroids. E-cadherin increased in lysates obtained from 3D-spheroids, while cleavage fragments were more evident in 2D-monolayers. N-cadherin expression was observed in very few PDAC cells grown in 2D-monolayers, but was more evident in 3D-spheroids. Some cells expressing COL-I were observed in 3D-spheroids. Podoplanin, expressed in collectively migrating cells, and αSMA were similarly expressed in both experimental conditions. The concomitant maintenance of the E-cadherin/β-catenin complex at cell boundaries supports the hypothesis of a collective migration for these cells, which is consistent with podoplanin expression.CONCLUSION: We show that a 3D-cell culture model could provide deeper insight into understanding the biology of PDAC and allow for the detection of marked differences in the phenotype of PDAC cells grown in 3D-spheroids. | Nicoletta Gagliano Giuseppe Celesti Lorenza Tacchini Stefano Pluchino Chiarella Sforza Marco Rasile Vincenza Valerio Luigi Laghi Vincenzo Conte Patrizia Procacci | 2016 | World Journal of Gastroenterology2016，22，18： | 0 |
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