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| 1 | Modeling of fluid-induced vibrations and identification of hydrodynamic forces on flow control valves显示文摘Dynamics and vibration of control valves under flow-induced vibration are analyzed. Hydrodynamic load characteristics and structural response under flow-induced vibration are mainly influenced by inertia, damping, elastic, geometric characteristics and hydraulic parameters. The purpose of this work is to investigate the dynamic behavior of control valves in the response to self-excited fluid flow. An analytical and numerical method is developed to simulate the dynamic and vibrational behavior of sliding dam valves, in response to flow excitation. In order to demonstrate the effectiveness of proposed model, the simulation results are validated with experimental ones. Finally, to achieve the optimal valve geometry, numerical results for various shapes of valves are compared. Rounded valve with the least amount of flow turbulence obtains lower fluctuations and vibration amplitude compared with the flat and steep valves. Simulation results demonstrate that with the optimal design requirements of valves, vibration amplitude can be reduced by an average to 30%. | Samad Mehrzad Ilgar Javanshir Ahmad Rahbar Ranji Seyyed Hadi Taheri | 2015 | Journal of Central South University2015，22，7： | 3 |
| 2 | MITOCHONDRIAL REDOX IMAGING FOR CANCER DIAGNOSTIC AND THERAPEUTIC STUDIES显示文摘Mitochondrial redox states provide important information about energy-linked biological processes and signaling events in tissues for various disease phenotypes including cancer.The redox scanning method developed at the Chance laboratory about 30 years ago has allowed 3D highresolution(∼50×50×10µm^(3))imaging of mitochondrial redox state in tissue on the basis of the fluorescence of NADH(reduced nicotinamide adenine dinucleotide)and Fp(oxidized flavoproteins including flavin adenine dinucleotide,i.e.,FAD).In this review,we illustrate its basic principles,recent technical developments,and biomedical applications to cancer diagnostic and therapeutic studies in small animal models.Recently developed calibration procedures for the redox imaging using reference standards allow quantification of nominal NADH and Fp concentrations,and the concentration-based redox ratios,e.g.,Fp/(Fp+NADH)and NADH/(Fp+NADH)in tissues.This calibration facilitates the comparison of redox imaging results acquired for different metabolic states at different times and/or with different instrumental settings.A redox imager using a CCD detector has been developed to acquire 3D images faster and with a higher in-plane resolution down to 10µm.Ex vivo imaging and in vivo imaging of tissue mitochondrial redox status have been demonstrated with the CCD imager.Applications of tissue redox imaging in small animal cancer models include metabolic imaging of glioma and myc-induced mouse mammary tumors,predicting the metastatic potentials of human melanoma and breast cancer mouse xenografts,differentiating precancerous and normal tissues,and monitoring the tumor treatment response to photodynamic therapy.Possible future directions for the development of redox imaging are also discussed. | LIN Z.LI HE N.XU MAHSA RANJI SHOKO NIOKA BRITTON CHANCE | 2009 | Journal of Innovative Optical Health Sciences2009，2，4： | 3 |
| 3 | -449 C>G polymorphism of NFKB1 gene,coding nuclear factor-kappa-B,is associated with the susceptibility to ulcerative colitis显示文摘AIM:To clarify the association between a polymorphism-449 C>G(rs72696119) in 5'-UTR of NFKB1 with ulcerative colitis(UC).METHODS:The studied population comprised 639 subjects,including patients with UC(UC cases,n = 174) and subjects without UC(controls,n = 465).We employed polymerase chain reaction-single strand conformation polymorphism to detect the gene polymorphism.RESULTS:The rs72696119 G allele frequencies in controls and UC cases were 33.4% and 38.5%,respectively(P = 0.10).Genotype frequency of the GG homozygote in UC cases was significantly higher than that in controls(P = 0.017),and the GG homozygote was significantly associated with susceptibility to UC [odds ratio(OR),1.88;95%CI,1.13-3.14].In male subjects,the GG homozygote was associated with an increased risk for UC(OR,3.10;95%CI,1.47-6.54;P = 0.0053),whereas this association was not found in female subjects.In addition,the GG homozygote was significantly associated with the risk of non-continuous disease(OR,2.06;95%CI,1.12-3.79;P = 0.029),not having total colitis(OR,2.40;95%CI,1.09-3.80,P = 0.040),disease which developed before 20 years of age(OR,2.80;95%CI,1.07-7.32,P = 0.041),no hospitalization(OR,2.28;95%CI,1.29-4.05;P = 0.0090) and with a maximum of 8 or less on the UCDAI score(OR,2.45;95%CI,1.23-4.93;P = 0.022).CONCLUSION:Our results provide evidence that NFKB1 polymorphism rs72696119 was significantly associated with the development of UC.This polymorphism influences the susceptibility to and pathophysiological features of UC. | Ranji Hayashi Tomomitsu Tahara Tsukasa Yamaaki Takashi Saito Kazuhiro Matsunaga Nobuhiko Hayashi Atsushi Fukumura Kazuaki Ozaki Masakatsu Nakamura Hisakazu Shiroeda Mikihiro Tsutsumi Tomoyuki Shibata Tomiyasu Arisawa | 2012 | World Journal of Gastroenterology2012，18，47： | 2 |
| 4 | microRNAs signature in IL-2-induced CD4^+ T cells and their potential targets 显示文摘 | Ranji N Sadeghizadeh M Karimipoor M | 2015 | Biochem Genet2015，53，78： | 1 |
| 5 | Improving antibiotic selec- tion a systematic review and quantitative analysis of quality improve- ment Strategies 显示文摘 | Steinman MA Ranji SR Shojania KG et aL | 2006 | Medical Care2006，44，7： | 1 |
| 6 | In vivo fluorometric assessment of cyclosporine on mitochondrial function during myocardial ischemia and reperfusion显示文摘 | MATSUBARA M RANJI M LESHNOWER BG | 2010 | Ann Thorac Surg2010，89，5： | 1 |
| 7 | Genetic polymorphisms of IL17A and pri-microRNA-938, targeting IL17A 3′-UTR, influence susceptibility to gastric cancer显示文摘 | Tomiyasu Arisawa Tomomitsu Tahara Hisakazu Shiroeda Yasuhito Matsue Takahiro Minato Tomoe Nomura Hideto Yamada Ranji Hayashi Takashi Saito Kazuhiro Matsunaga Tomoki Fukuyama Nobuhiko Hayashi Toshimi Otsuka Atsushi Fukumura Masakatsu Nakamura Tomoyuki Shib | 2012 | Human Immunology2012，，7： | 1 |
| 8 | A semi-analytical solution for forced vibrations response of rectangular orthotropic plates with various boundary conditions显示文摘 | Rahbar Ranji A Rostami Hoseynabadi H | 2010 | Journal of Mechanical Science and Technology2010，24，： | 1 |
| 9 | Silibinin - induced apoptosis and downregulation of mieroRNA - 21 and mi- croRNA- 155 in MCF-7 human breast cancer cells显示文摘 | Zadeh MM Motamed N Ranji N | 2016 | J Breast Cancer2016，19，1： | 1 |
| 10 | Evaluation of fatigue life of aluminum alloy wheels under radial loads显示文摘 | P R Ramamurty B Satyanarayana K Ranji K S Babu | 2007 | Engineering Failure Analysis2007，14，： | 1 |
| 11 | On-line preconcentration and recovery ofpalladium from waters using polyaniline(PANI)loaded in mini-column and determination by ICP-MS:Elimination of spectral interferences显示文摘 | Balarama Krishna M V Ranji M T ChandrasekaranK | 2009 | Talanta2009，79，： | 1 |
| 12 | Carbon fiberbismaleimide composites filled with nickel-coated singlewalled carbon nanotubes for lightning-strike protection显示文摘 | Divya K C Valery N K Ranji V | | 0，，： | 1 |
| 13 | Association between functional promoter polymorphisms of macrophage migration inhibitory factor (MIF) gene and ulcerative colitis in Japan显示文摘 | Hisakazu Shiroeda Tomomitsu Tahara Masakatsu Nakamura Tomoyuki Shibata Tomoe Nomura Hideto Yamada Ranji Hayashi Takashi Saito Masayoshi Yamada Tomoki Fukuyama Toshimi Otsuka Hirokazu Yano Kazuaki Ozaki Mutsumi Tsuchishima Mikihiro Tsutsumi Tomiyasu Arisaw | 2010 | Cytokine2010，，2： | 1 |
| 14 | Induced abortion in Iran: prevalence, reasons, and consequences显示文摘 | Ranji A | 2012 | J Midwifery Womens Health2012，57，5： | 1 |
| 15 | 综述:急性腹痛时予阿片类药物可能改变查体结果但不增加治疗失误显示文摘问题:急性腹痛患者予阿片类药物止痛时,是否会改变病史和查体结果并增加处理失误?
方法
资料来源:Medline(截至2006年5月),EMBASE/Excerpta Medica,相关研究的参考书目。
研究选择和评估:用随机对照试验(RCTs)和准随机对照试验比较急腹症患者给予阿片类药物与安慰剂治疗时二者之间的差异,并报告在病史、体格检查发现或临床处理方面的变化。共12个RCTs符合选择标准,其中成人中有9个(1062例)及儿童中有3个(291例)。每项研究的质量评估依据分配隐匿和盲法。多数RCTs存在方法学问题。 | Ranji SR Goldman LE Simel DL 彭浩(译) | 2007 | 英国医学杂志中文版2007，10，4： | 1 |
| 16 | Rapid response systems in adult academic medical centers显示文摘 | Wood KA Ranji SR Ide B | 2009 | Jt Comm J Qual Patient Saf2009，35，82： | 1 |
| 17 | Genetic polymorphisms of MAFK, encoding a small Maf protein, are associated with susceptibility to ulcerative colitis in Japan显示文摘AIM To investigate whether single nucleotide polymorphisms in maf protein K(MAFK), which encodes the MAFK, lead to increased susceptibility to ulcerative colitis in the Japanese population. METHODS This case control study examined the associations between MAFK single nucleotide polymorphisms(rs4268033 G>A, rs3735656 T>C and rs10226620 C>T) and ulcerative colitis susceptibility in 174 patients with ulcerative colitis(UC) cases, and 748 subjects without no lower abdominal symptoms, diarrhea or hematochezia(controls). In addition, as the second controls, we set 360 subjects, who have an irregular bowel movement without abnormal lower endoscopic findings(IBM controls).RESULTS The genotype frequency of rs4268033 AA and allelic frequency of the rs4268033 A allele were significantly higher in the UC cases than in both controls(P = 0.0005 and < 0.0001, P = 0.015 and 0.0027 vs controls and IBM controls, respectively). Logistic regression analysis after adjustment for age and gender showed that the rs4268033 AA and rs3735656 CC genotypes were significantly associated with susceptibility to UC development(OR = 2.63, 95%CI: 1.61-4.30, P = 0.0001 and OR = 1.81; 95%CI: 1.12-2.94, P = 0.015, respectively). Similar findings were observed by the comparison with IBM controls. In addition, the rs4268033 AA genotype was significantly associated with all phenotypes of UC except early onset. There was no significant association between rs10226620 and ulcerative colitis. CONCLUSION Our results provide the first evidence that MAFK genetic polymorphisms are significantly associated with susceptibility to UC development. In particular, rs4268033 is closely associated with an increased risk for the development of UC. | Tomiyasu Arisawa Masakatsu Nakamura Toshimi Otsuka Wu Jing Naoko Sakurai Hikaru Takano Tasuku Hayashi Masafumi Ota Tomoe Nomura Ranji Hayashi Takeo Shimasaki Tomomitsu Tahara Tomoyuki Shibata | 2017 | World Journal of Gastroenterology2017，23，29： | 1 |
| 18 | Effects of quality improvementstrategies for type 2 diabetes on glycemic control: a meta-regression analysis显示文摘 | ShojaniaKG Ranji SR McDonald KM | 2006 | JAMA2006，296，： | 1 |
| 19 | Induced abortion in Iran: prevalence, reasons, andconsequences 显示文摘 | Ranji A | 2012 | J Midwifery Womens Health2012，57，5： | 1 |
| 20 | Improving antibiotic selection:a systematic review and quantitative analysis of quality improvement strategies显示文摘 | Steinman MA Ranji SR Shojania KG | 2006 | Medical Care2006，44，7： | 1 |
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