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| 1 | Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma显示文摘AIM: To characterize the alpha-fetoprotein (AFP) positive and negative hepatocellular carcinoma (HCC) samples.METHODS: Thirty-seven paraffin-embedded human HCC samples were analyzed by immunohistochemistry for the following antigens: AFP, β-catenin, p53, CD44, MSH-2,MLH-1, and HNF-4. The tumors were divided into two groups based on the AFP expression. The immunophenotypic data and important clinical parameters were studied between the two groups.RESULTS: Twenty-one of the thirty-seven examined HCCs were AFP positive. Seven with nuclear p53 staining were AFP positive, while seven tumors with nuclear β-catenin staining were AFP negative. CD44 staining and high histological tumor grade were more frequent among the AFP-positive HCCs. The other immunophenotypical and dinical parameters did not show statistically significant difference in their distribution between the AFP positive and negative samples.CONCLUSION: AFP expression in HCC correlates with unfavorable prognostic factors, while nuclear β-catenin positivity is more common among the AFP-negative liver tumors. This observation supports the microarray data onin vivo human tumors. | Dénes Grg János Regly-Mérei Sándor Paku László Kopper Péter Nagy | 2005 | World Journal of Gastroenterology2005，11，32： | 6 |
| 2 | Acute gouty synovitis associated with 'urate milk' 显示文摘 | FAM A G REIS M D SZALAI J P | 1997 | J Rheumatol1997，24，12： | 1 |
| 3 | Vapor Bubble Departure in Forced Convection Boiling显示文摘 | Rei R Bernhard D M | 1993 | Int J Heat and Mass Transfer1993，36，： | 1 |
| 4 | Sulfate reduction in acidogenic phase anaerobic-digestion 显示文摘 | REIS M A M GONCALVES L M D CARRONDO M J T | 1988 | Water Science and Technology1988，20，1112： | 1 |
| 5 | Tailored Welded Blanks-an Experimental and Numerical Study in Sheet Metal Forming on the Effect of Welding显示文摘 | Reis A Teixeira P Ferreira D J | | 0，，： | 1 |
| 6 | Genetic pro- file of gliosarcomas显示文摘 | Reis R M Konu-Lebleblicioglu D Lopes J M | 2000 | Am J Pathol2000，156，2： | 1 |
| 7 | Biological dinitro- gen fixation in Gramineae and palm trees显示文摘 | Reis V M Baldani J I Baldani V L D | 2000 | Critical Rev Plant Sci2000，19，3： | 1 |
| 8 | Intrinsic neurons of fastigial nucleus mediate neurogenic neuroproteetion against excitotoxic and isehemic neuronal injury in rat显示文摘 | GLICKSTE1N S B GOLANOV E V REIS D J | 1999 | J Neurosci1999，19，24： | 1 |
| 9 | Tumor size and surviv alinbreast cancer a reappraisal显示文摘 | Foulkes W D Reis - Filho J S Narod S A | 2010 | Nat RevClinOncol2010，7，： | 1 |
| 10 | Microhardness of Ni-Cr alloys under different casting conditions显示文摘 | Bauer J R Loguercio A D Reis A | 2006 | Braz Oral Res2006，20，1： | 1 |
| 11 | Experimental Investigation of the Mechanical Properties of Polymer Mortars with Nanoparticles显示文摘 | REIS J M L MOREIRA D C NUNES L C S | | 0，，18： | 1 |
| 12 | Changes in regional blood flow and cardiodynamics evoked by electrical stimulation of the fastigial nucleus in the cat and their similarity to orthostatic reflexes 显示文摘 | Doba N Reis D J | 1972 | J Physiol1972，227，3： | 1 |
| 13 | Ex- pression of nonadrenergic imidazoline sites in ehro- marlin cells and mitochondrial membranes of bovine adrenal medulla显示文摘 | REGUNATHAN S MEELEY M P REIS D J | 1993 | Biochem Pharmacol1993，45，： | 1 |
| 14 | Brief electrical stimulation of cerebellar fastigial nucleus conditions long-lasting salvage from focal cerebral ischemia:conditioned central neurogenic neuroprotection显示文摘 | Reis D J Kobylarz K Yamamoto S | 1998 | Brain Res1998，780，： | 1 |
| 15 | Anatomical characterization of a novel reticulospinal vasodepressor area in the rat medulla oblongata显示文摘 | Aicher S A Reis D J Ruggiero D A | 1994 | Neuroscience1994，60，3： | 1 |
| 16 | Neuroprotective electrical stimulation of cerebellar fastigial nucleus attenuates expression of periinfarction depolarizing waves and inhibits cortical spreading depression显示文摘 | Golanov E V Reis D J | 1999 | Brain Res1999，818，： | 1 |
| 17 | Accentuated osteoclastic response to parathy- roid hormone undermines bone mass acquisition in osteonectin-null mice 显示文摘 | Machado do Reis L Kessler CB Adams D J | 2008 | Bone2008，43，2： | 1 |
| 18 | Mimosine,administered orally,and two related compounds as chemical defleecing agents for sheep显示文摘 | REIS P J TUNKS D A DOWNES A M | 1978 | J Agric Res1978，29，8： | 1 |
| 19 | Electrical stimulation of cerebellar fastigial nucleus reduces ischemic infarction elicited by middle cerebral artery occlusion in rat显示文摘 | Reis D J Berger SB Underwood MD | 1991 | J Cereb Blood Flow Metab1991，11，5： | 1 |
| 20 | Sulfate Reduction in Acidogenic Phase Anaerobic Digestion显示文摘 | REIS M A M GONCALVES L M D CARRONDO M J T | 1988 | Water Science and Technology1988，20，1112： | 1 |
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