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| 1 | Novel concepts in radiation-induced cardiovascular disease显示文摘Radiation-induced cardiovascular disease(RICVD) is the most common nonmalignant cause of morbidity and mortality among cancer survivors who have undergone mediastinal radiation therapy(RT).Cardiovascular complications include effusive or constrictive pericarditis,cardiomyopathy,valvular heart disease,and coronary/vascular disease.These are pathophysiologically distinct disease entities whose prevalence varies depending on the timing and extent of radiation exposure to the heart and great vessels.Although refinements in RT dosimetry and shielding will inevitably limit future cases of RICVD,the increasing number of long-term cancer survivors,including those treated with older higher-dose RT regimens,will ensure a steady flow of afflicted patients for the foreseeable future.Thus,there is a pressing need for enhanced understanding of the disease mechanisms,and improved detection methods and treatment strategies.Newly characterized mechanisms responsible for the establishment of chronic fibrosis,such as oxidative stress,inflammation and epigenetic modifications,are discussed and linked to potential treatments currently under study.Novel imaging modalities may serve as powerful screening tools in RICVD,and recent research and expert opinion advocating their use is introduced.Data arguing for the aggressive use of percutaneous interventions,such as transcutaneous valve replacement and drug-eluting stents,are examined and considered in the context of prior therapeutic approaches.RICVD and its treatment options are the subject of a rich and dynamic body of research,and patients who are at risk or suffering from this disease will benefit from the care of physicians with specialty expertise in the emerging field of cardiooncology. | Jason R Cuomo Gyanendra K Sharma Preston D Conger Neal L Weintraub | 2016 | World Journal of Cardiology2016，8，9： | 17 |
| 2 | Inoprint lithography with 25-nanometer resolation显示文摘 | Stephen Y C Pete R K Preston J R | 1996 | Science1996，272，5： | 1 |
| 3 | Radical reaction of C60显示文摘 | Krusic P J Wassermann E Keizer P N Morton J R Preston K F | 1991 | Science1991，254，： | 1 |
| 4 | Effects of frost and immaturity on the quality of a Canadian hard red spring wheat显示文摘 | Preston K R Kilborn R H Morgan B C | 1991 | Cereal Chem1991，68，2： | 1 |
| 5 | A comparison of methods for the prediction of Cantonese noodle color 显示文摘 | Kruger J E Matsuo R R Preston K | 1992 | Canadian Journal of Plant Science1992，72，： | 1 |
| 6 | 1984, Deternlination of amino acids in wheat and barley by near infrared reflectance spectroscopy 显示文摘 | Williams P C K R Preston K H Norris P M Starky | 1984 | J Food Scielwe1984，49，： | 1 |
| 7 | Development of a high extraction flour for the GRL Pilot Mill to evaluate Canadian wheat potential for the Chinese market 显示文摘 | Dexter J E Preston K R Matsuo R R | 1984 | Can Inst Food Sci Technol J1984，14，： | 1 |
| 8 | Relationship of exoproteolytic and endoproteolytic activity to storage protein hydrolysis in germinating du- rum and hard red spring wheat 显示文摘 | Preston K R Dexter J E Kruger J E | 1978 | Cereal Chemistry1978，，55： | 1 |
| 9 | Determination of amino acid in wheat and arley by NIRS显示文摘 | Williams P C Preston K R | 1984 | Food Sci1984，49，： | 1 |
| 10 | Matching ruminant production system with available resources in the tropics and sub-tropics 显示文摘 | Preston T R Leng K A | 1987 | Penambul Books Armidal1987，30，20： | 1 |
| 11 | Development of a high extraction flour for the GRL pilot mill to evaluate Canadian wheat potential for the Chinese market显示文摘 | Dexter J E Preston K R Matsuo R R | 1984 | Canadian Institute of Food Science and Technology Journal1984，14，： | 1 |
| 12 | Fusarium head blight: effect on the milling and baking of some Canadian wheats显示文摘 | Dexter J E Clear R M Preston K R | 1996 | Cereal Chemistry1996，73，6： | 1 |
| 13 | The effects of protein content and starch damage on the physical dough properties and bread making quality of Canadian durum wheat 显示文摘 | Dexter J E Preston K R Martin D G | 1994 | Journal of Cereal Science1994，20，： | 1 |
| 14 | Abuse potential and pharmacologic comparison of tramadol and morphine显示文摘 | Preston K L Jasinski D R Testa M | 1991 | Drug Alcohol Depend1991，27，1： | 1 |
| 15 | SPECT brain imaging abnormalities in attention deficit hyperactivity disorder显示文摘 | Sieg K G Gaffney G R Preston D F | 1995 | Clin Nucl Med1995，20，1： | 1 |
| 16 | Physiology of sunburn development in apples显示文摘 | Andrews Preston K Johnson James R | 1996 | Good Fruit Grower1996，47，12： | 1 |
| 17 | Imprint of Sub-25nm Vias and Trenches in Polymers显示文摘 | Stephen Y C Peter R K Preston J R | 1995 | Applied Physics Letters1995，67，21： | 1 |
| 18 | A comparison of methodsfor the prediction of Cantonese noodle colour显示文摘 | Kruger J E Matsuo R R Preston K | 1992 | CanadianJournal of Plant Science1992，72，： | 1 |
| 19 | The reinforcing and subjective effects of morphine in post - addicts:a doseresponse study显示文摘 | Lamb R J Preston K L Schindler C W | 1991 | J Pharmacol Exp Ther1991，259，3： | 1 |
| 20 | Evaluation of tilidine formorphine-like subjects and euphoria显示文摘 | Jasinski D R Preston K L | 1986 | Drug Alcohol Dep1986，18，3： | 1 |
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