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| 1 | Shedding light on bi?oscience显示文摘 | Cole MJ Pirity M Hadjantonakis AK | 2003 | EMBO Rep2003，4，： | 1 |
| 2 | P-glycoprotein is overexpressed and functional in severely heat-shocked hepatoma cells显示文摘 | Hever-Szabo A Pirity M Szathmari M | 1998 | Anticancer Res1998，18，4： | 1 |
| 3 | Rybp,a polycombcomplex-associated protein,is required for mouse eyedevelopment显示文摘 | Pirity MK Wang WL Wolf LV | 2007 | BMC Dev Biol2007，7，： | 1 |
| 4 | Rybp/DEDAF is required for early postimplantation and for central nervous system development显示文摘 | Pirity M K Locker J Schreiber-Agus N | 2005 | Mol Cell Biol2005，25，16： | 1 |
| 5 | Rybp, a polycomb complex-associated protein, is required for mouse eye development 显示文摘 | Pirity M K Wang W L Wolf L V | 2007 | BMC Dev Biol2007，7，： | 1 |
| 6 | Overexpression of P-glycoprotein in heat-and/or drug-resistance hepatoma variants显示文摘 | Pirity M Hever-Szabo A Venetianer A | 1996 | Cytotechnology1996，19，3： | 1 |
| 7 | Rybp/DEDAF is required for early postimplantation and for central nervous system development 显示文摘 | Pirity M K Locker J Schreiber-Agus N | 2005 | Mol Cell Biol2005，25，16： | 1 |
| 8 | P-glycoprotein is overexpressed and functional in severely heat-shocked hepatoma cells显示文摘 | Hever-Szabo A Pirity M Szathmari M | 1998 | Anticancer-Res1998，18，4： | 1 |
| 9 | Overexpression of P-glycoprotein in heat-and/or drug-resistance hepatoma variants显示文摘 | Pirity M Hever-Szabo A Venetianer A | 1996 | Cytotechnology1996，19，： | 1 |
| 10 | Shedding light on bioscience显示文摘 | Cole M J Pirity M Hadjantonakis A K | 2003 | EMBO Rep2003，4，9： | 1 |
| 11 | Lessons learn-ed from Myc/Max/Mad knockout mice 显示文摘 | PIRITY M BLANCK J K SCHREIBER AGUS N | 2006 | CTMI2006，302，： | 1 |
| 12 | Shedding light on bioscience 显示文摘 | Cole M J Pirity M Hadjantonakis AK | 2003 | EMBO Rep2003，4，9： | 1 |
| 13 | Generation of rabbit pluripotent stem cell lines显示文摘 | Z. Tancos C. Nemes Z. Polgar E. Gocza N. Daniel T.A.E. Stout P. Maraghechi M.K. Pirity P. Osteil Y. Tapponnier S. Markossian M. Godet M. Afanassieff Z. Bosze V. Duranthon P. Savatier A. Dinnyes | 2012 | Theriogenology2012，，8： | 1 |
| 14 | Overexpression of P-glycoprotein in heat- and/or drug-resistant hepatoma variants显示文摘 | Pirity M Hever-Szabo A Venetianer A | 1996 | Cytotechnology1996，19，3： | 1 |
| 15 | Embryoid body formation from embryonic and induced pluripotent stem cells:Benefits of bioreactors显示文摘Embryonic stem(ES)cells have the ability to differ-entiate into all germ layers,holding great promise not only for a model of early embryonic development but also for a robust cell source for cell-replacement therapies and for drug screening.Embryoid body (EB)formation from ES cells is a common method for producing different cell lineages for further applications. However,conventional techniques such as hanging drop or static suspension culture are either inherently incapable of large scale production or exhibit limited control over cell aggregation during EB formation and subsequent EB aggregation.For standardized mass EB production,a well defined scale-up platform is necessary.Recently,novel scenario methods of EB formation in hydrodynamic conditions created by bioreactor culture systems using stirred suspension systems(spinner flasks),rotating cell culture system and rotary orbital culture have allowed large-scale EB formation.Their use allows for continuous monitoring and control of the physical and chemical environment which is difficult to achieve by traditional methods.This review summarizes the current state of production of EBs derived from pluripotent cells in various culture systems.Furthermore,an overview of high quality EB formation strategies coupled with systems for in vitro differentiation into various cell types to be applied in cell replacement therapy is provided in this review. Recently,new insights in induced pluripotent stem(iPS) cell technology showed that differentiation and lineage commitment are not irreversible processes and this has opened new avenues in stem cell research.These cells are equivalent to ES cells in terms of both self-renewal and differentiation capacity.Hence,culture systems for expansion and differentiation of iPS cells can also apply methodologies developed with ES cells,although direct evidence of their use for iPS cells is still limited. | Sasitorn Rungarunlert Mongkol Techakumphu Melinda K Pirity Andras Dinnyes | 2009 | World Journal of Stem Cells2009，1，1： | 1 |
| 16 | P-glycoprotein is overexpressed and functional in severely heat-shocked hepatoma cells显示文摘 | Hever-Szabo A Pirity M Szathmari M | 1998 | Anticancer Res1998，18，4： | 1 |
| 17 | Germline competence of mouse ES and iPS cell lines: Chimera technologies and genetic background显示文摘In mice,gene targeting by homologous recombination continues to play an essential role in the understanding of functional genomics.This strategy allows precise location of the site of transgene integration and is most commonly used to ablate gene expression('knock-out'),or to introduce mutant or modified alleles at the locus of interest('knock-in').The efficacy of producing live,transgenic mice challenges our understanding of this complex process,and of the factors which influence germline competence of embryonic stem cell lines.Increasingly,evidence indicates that culture conditions and in vitro manipulation can affect the germline-competence of Embryonic Stem cell(ES cell) lines by accumulation of chromosome abnormalities and/or epigenetic alterations of the ES cell genome. The effectiveness of ES cell derivation is greatly strain-dependent and it may also influence the germline transmission capability.Recent technical improvements in the production of germline chimeras have been focused on means of generating ES cells lines with a higher germline potential.There are a number of options for generating chimeras from ES cells (ES chimera mice);however,each method has its advantages and disadvantages.Recent developments in induced pluripotent stem(iPS)cell technology have opened new avenues for generation of animals from genetically modified somatic cells by means of chimera technologies.The aim of this review is to give a brief account of how the factors mentioned above are influencing the germline transmission capacity and the developmental potential of mouse pluripotent stem cell lines.The most recent methods for generating specifically ES and iPS chimera mice,including the advantages and disadvantages of each method are also discussed. | Ana Claudia Carstea Melinda K Pirity Andras Dinnyes | 2009 | World Journal of Stem Cells2009，1，1： | 1 |
| 18 | Mxil -SRa : a no el Mxil isoform with enhanced transcriptional repression polential 显示文摘 | Dugasl-Dat aeq C Pirity M Blanck JK | 2004 | Oncogene2004，23，55： | 1 |
| 19 | The function of heat-shock proteins in stress tolerance显示文摘 | Venetianer A Pirity M Hever-Szabo A | 1994 | Cell Biology International1994，18，： | 1 |
| 20 | Mxil -SR : a novel Mxil isoform with enhanced transcriptional repression potential 显示文摘 | Dugast-Darzacq C Pirity M Blanek JK | 2004 | Oncogene2004，23，55： | 1 |
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