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| 1 | Management of liver transplantation biliary stricture: Results from a tertiary hospital显示文摘AIM: To review results of endoscopic treatment for anastomotic biliary strictures after orthotopic liver transplantation(OLT) during an 8-year period. METHODS: This is a retrospective review of all endoscopic retrograde cholangiopancreatographys(ERCPs) performed between May 2006 and June 2014 in deceased OLT recipients with anastomotic stricture at a tertiary care hospital. Patients were divided into 2 groups, according to the type of stent used(multiple plastic or covered self-expandable metal stents), which was chose on a case-by-case basis and their characteristics. The primary outcome was anastomotic stricture resolution rate determined if there was no more than a minimum waist at cholangiography and a 10 mm balloon could easily pass through the anastomosis with no need for further intervention after final stent removal. Secondary outcomes were technical successrate, number or ERCPs required per patient, number of stents placed, stent indwelling, stricture recurrence rate and therapy for recurrent anastomotic biliary stricture(AS). Stricture recurrence was defined as clinical laboratorial and/or imaging evidence of obstruction at the anastomosis level, after it was considered completely treated, requiring subsequent interventional procedure.RESULTS: A total of 195 post-OLT patients were assessed for eligibility. One hundred and sixty-four(164) patients were diagnosed with anastomotic biliary stricture. ERCP was successfully performed in 157/164(95.7%) patients with AS, that were treated with either multiple plastic(n = 109) or metallic billiary stents(n = 48). Mean treatment duration, number of procedures and stents required were lower in the metal stent group. Acute pancreatitis was the most common procedure related complication, occurring in 17.1% in the covered self-expandable metal stents(c SEMS) and 4.1% in the multiple plastic stent(MPS) group. Migration was the most frequent stent related complication, observed in 4.3% and 5.5%(c SEMS and MPS respectively). Stricture resolution was achieved in 86.8% in the c SEMS group and in 91% in MPS group. Stricture recurrence after a median follow up of 20 mo was observed in 10(30.3%) patients in the c SEMS and 7(7.7%) in the plastic stent group, a statistically significant difference(P = 0.0017). Successful stricture resolution after secondary treatment was achieved in 66.6% and 62.5% of patients respectively in the c SEMS and plastic stents groups. CONCLUSION: Multiple plastic stents are currently the first treatment option for AS in patients with duct-toduct anastomosis. c SEMS was associated with increased pancreatitis risk and higher recurrence rate. | Fernanda Prata Martins Michel Kahaleh Angelo P Ferrari | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，7： | 10 |
| 2 | Recent advances in amino acid analysis by capillary electrophoresis显示文摘 | PRATA C BONNAFOUS P FRAYSSE N | 2001 | Electrophoresis2001，22，19： | 1 |
| 3 | Recent advances in amino acid analysis by capillary electrophoresis 显示文摘 | Prata C Bonnafous P Fraysse N | 2001 | Electrophoresis2001，22，19： | 1 |
| 4 | Olfactory mucosa auto grafts in human spinal cord injury: a pilot clinical study 显示文摘 | Lima C Pratas -Vital J Escada P | 2006 | J Spinal Cord Med2006，29，3： | 1 |
| 5 | GReEn:A tool for effi- cient compression of genome resequencing data显示文摘 | Pinho A J Pratas D Garcia S P | 2012 | Nu- cleic Acids Research2012，40，4： | 1 |
| 6 | Olfactorymucosal autografts and rehabilitation for chronic traumatic spinal cord injury显示文摘 | Lima C Escada P Pratas VJ | | 0，，： | 1 |
| 7 | Theimpaet ofthe diurnal variation of albedo on the remote sensing of the daily mean albedo of grassland显示文摘 | Grant I F Prata A J Cechet R P | 2000 | Journal of Applied Meteorology2000，39，2： | 1 |
| 8 | The impact of the diurnal variation of albedo on the remote sensing of the daily mean albedo of grassland显示文摘 | Grant I F Prata A J Cechet R P | 2000 | Journal of Applied Meteorology2000，39，2： | 1 |
| 9 | A fast and elitist muhiob- jective genetic algorithm: NSGA- U 显示文摘 | DEB K PRATA P AGAWAL S | 2002 | IEEE Transactions on Evo- lutionary Computation2002，6，2： | 1 |
| 10 | Olfactory mucosa auto grafts in human spinal cord injury:a pilot clinical study显示文摘 | Pratas -Vital J Escada P | 2006 | J Spinal Cord Med2006，29，3： | 1 |
| 11 | Recent advances in amino acids analysis by capillary electrophoresis 显示文摘 | Prata C Bonnafouse P Fraysse N | 2001 | Electrophoresis2001，22，： | 1 |
| 12 | A Fast and Elitist Multiobjective Genetic Algorithm NSGA-Ⅱ 显示文摘 | Deb K Prata P A Agarwal S | 2002 | IEEE Transactions on Evolutionary Computa- tion2002，，6： | 1 |
| 13 | A fast and elitist multiobjective genetic algorithm: NSGA-II显示文摘 | DEB K PRATA P A AGARWAL S | 2002 | IEEE Transac- tions on Evolutionary Computation2002，，6： | 1 |
| 14 | Selective chemical extraction of heavy metals in tailings and soils contaminated by mining activity : environmental implications 显示文摘 | Favas P J C Pratas J Gomes M E P | 2011 | Geochemical Exploration2011，111，31： | 1 |
| 15 | Hormonal manipulation and factors that influence the reproductive efficiency of dairy cows 显示文摘 | Monteiro JOnior P Prata A B Spies C | 2015 | CiSncia VeterinOria nos Tr6picos2015，18，2： | 1 |
| 16 | Selective chemicalextraction of heavy metals in tailings and soils contaminatedby mining activity :environmental implications显示文摘 | Favas P J C Pratas J Gomes M E P | 2011 | Journal ofGeochemical Exploration2011，111，3： | 1 |
| 17 | Recent advances in amino acid analysis by capillary electrophoresis显示文摘 | Prata C Bonnafous P Fraysse N | 2001 | Electrophoresis2001，22，19： | 1 |
| 18 | Recent advances in amino acid analysis by capillary electrophoresis 显示文摘 | Prata C Bonnafous P Fraysse N | 2001 | Electrophoresis2001，22，19： | 1 |
| 19 | NODA-GATOC, a New Helatorcoupled Somatosta- tin Analogue Labeled With E67/68Ga] and for SPECT, PET, and Targeted Therapeutic Applica- tions of Somatostatin Receptor (hsst2) Expressing Tumors显示文摘 | Eisenwiener K P Prata M I Buschmann I | 2002 | Bioconjugate Chem2002，13，： | 1 |
| 20 | Potential of aquatic plants for phytofiltration of uranium-contaminated waters in laboratory conditions显示文摘 | Pratas J Paulo C Favas P J C | 2014 | Ecological Engineering2014，69，： | 1 |
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