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| 1 | Is intra-operative cholangiography necessary during laparoscopic cholecystectomy? A multicentre rural experience from a developing world country显示文摘AIM: To evaluate the feasibility and safety of performing laparoscopic cholecystectomy (LC) in nonteaching rural hospitals of a developing country without intra-operative cholangiography (IOC). To evaluate the possibility of reduction of costs and hospital stay for patients undergoing LC.METHODS: A prospective analysis of patients with symptomatic benign diseases of gall bladder undergoing LC in three non-teaching rural hospitals of Kashmir Valley from Jan 2001 to Jan 2007. The cohort represented a sample of patients requiring LC, aged 13 to 78 (mean 47.2) years. Main outcome parameters included mortality, complications, re-operation, conversion to open procedure without resorting to IOC, reduction in costs borne by the hospital, and the duration of hospital stay.RESULTS: Twelve hundred and sixty-seven patients (976 females/291 males) underwent laparoscopic cholecystectomy. Twenty-three cases were converted to open procedures; 12 patients developed port site infection, nobody died because of the procedure. One patient had common bile duct (CBD) injury, 4 patients had biliary leak, and 4 patients had subcutaneous emphysema. One cholecystohepatic duct was detected and managed intraoperatively, 1 patient had retained CBD stones, while 1 patient had retained cystic duct stones. Incidental gallbladder malignancy was detected in 2 cases. No long-term complications were detected up to now.CONCLUSION: LC can be performed safely even in non-teaching rural hospitals of a developing country provided proper equipment is available and the surgeons and other team members are well trained in the procedure. It is stressed that IOC is not essential to prevent biliary tract injuries and missed CBD stones. The costs to the patient and the hospital can be minimized by using reusable instruments, intracorporeal sutures, and condoms instead of titanium clips and endobags. | Iqbal Saleem Mir Mir Mohsin Omar Kirmani Tafazul Majid Khurshid Wani Mehmood-ul Hassan Javed Naqshbandi Mohammed Maqbool | 2007 | World Journal of Gastroenterology2007，13，33： | 3 |
| 2 | A Preliminary Study on Combination Therapy of Artemisinin Dimer Oxime and Topotecan against Nonsmall Cell Lung Cancer in Mice显示文摘Background: Artemisinin dimer oxime – dimer molecule synthesized from artemisinin possesses high bioavailability and marked in vitro anticancer activities against solid tumor?derived cell lines, endothelial cell proliferation, migration, and angiogenic processes. Numerous murine models have been developed to study human cancer. The most widely used models are the human tumor xenograft mouse model. Materials and Methods: In this study, human tumor cells(NCI?H640, 1 × 107 in 100 μL) are implanted subcutaneously, or 1 × 107 in 50 μL in the thoracic cavity, in athymic nude mice(nu/nu). The implanted cells were allowed to grow for 10 days before initiation of drug treatment(dimer oxime and topotecan, ip). Tumor volume and thoracic/body weight ratio were recorded. Results: We successfully established subcutaneous and thoracic xenografts with human nonsmall cell lung cancer cell line xenografts in athymic nude mice in only 10 days. Using these models, we attempted treatment of xenografts with topotecan – a known anticancer drug and artemisinin dimer oxime or combination of these two drugs. Combination therapy showed a significant reduction in tumor volume and tumor/body weight. Treatments with combination of topotecan and dimer oxime resulted in the reduced mortality rates in comparison with untreated mice. Conclusions: Xenograft tumor models are useful for preclinical screening of new pharmacophores. From this preliminary study, it appears that combination of dimer oxime and topotecan may be used as chemotherapeutic agents against nonsmall cell lung cancer. Further studies are needed to evaluate other combination treatment regimens as well as the mechanism(s) of action. | Mohammad K.Ashfaq Mohamed Sadek Abdel-Bakky Mir Tahir Maqbool Waseem Gul Mahmoud A.ElSohly | 2018 | World Journal of Traditional Chinese Medicine2018，4，1： | 3 |
| 3 | Synthesis and properties of symmetrically substituted 4,4'- Bis ( 1,3,5 -triazinyl) - Diamino Stilbene -2,2 '- Disulfonic acid derivatives as UV absorbing and fluorescent whitening agents 显示文摘 | Maqbool Hussain Khalid Mohammed Khanl Syed Ishrat Ali | 2009 | Fibers and Poly- mers2009，10，4： | 1 |
| 4 | 阿拉伯胶和香精油对香蕉及番木瓜贮藏过程中炭疽病及品质的控制效果显示文摘 | Mehdi Maqbool Asgar Ali Peter G.Alderson Mahmud Tengku Muda Mohamed Yasmeen Siddiqui Noosheen Zahid | 2011 | 保鲜与加工2011，，05： | 1 |
| 5 | Microbial quality of shrimp products of export trade produced from aquacuhured shrimp显示文摘 | Mohamed Hatha A A Maqbool T K | 2003 | International Journal of Food Microbiology2003，82，： | 1 |
| 6 | Microbial quality of shrimp products of export trade produced from aquacultured shrimp显示文摘 | MOHAMED HATHA A A MAQBOOL T K SURESH KUMAR S | 2003 | International Journal of Food Microbiology2003，82，3： | 1 |
| 7 | Microbial quality of shrimp products of export trade produced from aquacultured shrimp显示文摘 | MOHAMED H A MAQBOOL T K SURESH K S | 2003 | Int J Food Microbiol2003，82，3： | 1 |
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