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| 1 | Multicenter study of endoscopic preoperative biliary drainage for malignant distal biliary obstruction显示文摘AIM: To determine the optimal method of endoscopic preoperative biliary drainage for malignant distal biliary obstruction.METHODS: Multicenter retrospective study was conducted in patients who underwent plastic stent(PS) or nasobiliary catheter(NBC) placement for resectable malignant distal biliary obstruction followed by surgery between January 2010 and March 2012. Procedurerelated adverse events, stent/catheter dysfunction(occlusion or migration of PS/NBC, developmentof cholangitis, or other conditions that required repeat endoscopic biliary intervention), and jaundice resolution(bilirubin level < 3.0 mg/d L) were evaluated. Cumulative incidence of jaundice resolution and dysfunction of PS/NBC were estimated using competing risk analysis. Patient characteristics and preoperative biliary drainage were also evaluated for association with the time to jaundice resolution and PS/NBC dysfunction using competing risk regression analysis.RESULTS: In total, 419 patients were included in the study(PS, 253 and NBC, 166). Primary cancers included pancreatic cancer in 194 patients(46%), bile duct cancer in 172(41%), gallbladder cancer in three(1%), and ampullary cancer in 50(12%). The median serum total bilirubin was 7.8 mg/d L and 324 patients(77%) had ≥ 3.0 mg/d L. During the median time to surgery of 29 d [interquartile range(IQR), 30-39 d]. PS/NBC dysfunction rate was 35% for PS and 18% for NBC [Subdistribution hazard ratio(SHR) = 4.76; 95%CI: 2.44-10.0, P < 0.001]; the pig-tailed tip was a risk factor for PS dysfunction. Jaundice resolution was achieved in 85% of patients and did not depend on the drainage method(PS or NBC).CONCLUSION: PS has insufficient patency for preoperative biliary drainage. Given the drawbacks of external drainage via NBC, an alternative method of internal drainage should be explored. | Naoki Sasahira Tsuyoshi Hamada Osamu Togawa Ryuichi Yamamoto Tomohisa Iwai Kiichi Tamada Yoshiaki Kawaguchi Kenji Shimura Takero Koike Yu Yoshida Kazuya Sugimori Shomei Ryozawa Toshiharu Kakimoto Ko Nishikawa Katsuya Kitamura Tsunao Imamura Masafumi Mizuide Nobuo Toda Iruru Maetani Yuji Sakai Takao Itoi Masatsugu Nagahama Yousuke Nakai Hiroyuki Isayama | 2016 | World Journal of Gastroenterology2016，22，14： | 18 |
| 2 | Identification of monoclonal insulin autoantibodies in insulin autoimmune syndrome associated with HLA - DRB1 * 0401 显示文摘 | Mizuide M Kashima K | 2000 | Horm Res2000，54，1： | 1 |
| 3 | NO x emission characteristics in rich–lean combustion of hydrogen显示文摘 | Toshio Shudo Takashi Mizuide | 2002 | JSAE Review2002，，1： | 1 |
| 4 | Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski显示文摘 | Takeda M Mizuide M Oka M | 2004 | Mol Biol Cell2004，15，3： | 1 |
| 5 | NOx emission characteristics in rich-lean combustion of hydrogen显示文摘 | SHUDO T MIZUIDE T | 2002 | Jsae Review2002，23，1： | 1 |
| 6 | A Prospective Randomized Controlled Trial of AJG522 versus Standard PEG + E as Bowel Preparation for Colonoscopy显示文摘 | Toshihiko Sagawa Ken Sato Taku Tomizawa Masafumi Mizuide Hidetoshi Yasuoka Yasuyuki Shimoyama Shiko Kuribayashi Satoru Kakizaki Osamu Kawamura Motoyasu Kusano Masanobu Yamada Sachiyo Nomura | 2015 | BioMed Research International2015，，： | 1 |
| 7 | Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN 显示文摘 | Mizuide M Hara T Furuya T | 2003 | J Biol Chem2003，278，1： | 1 |
| 8 | Identification ofmonoclonalinsulinautoantibodies in insulin autoinunune syndromeassociated with HLA- DRBI*0401显示文摘 | Mur akami M Mizuide M Kashima K | 2000 | Horm Res2000，54，1： | 1 |
| 9 | Interaction with Smad4 is indispensable for suppression of BMP signaling by c-Ski显示文摘 | Takeda M Mizuide M Oka M | 2004 | Mol Biol Cell2004，15，3： | 1 |
| 10 | A sensor measuring the Fourier coefficients of the magnetic flux density for pipe crack detection using the magnetic flux leakage method 显示文摘 | NARA T TAKANASHI Y MIZUIDE M | 2011 | Journal of Applied Physics2011，109，7： | 1 |
| 11 | A sensor measuring the Fourier coefficients of the magnetic flux density for pipe crack detection using the magnetic flux leakage method显示文摘 | Nara T Takanashi Y Mizuide M | 2011 | Journal of Applied Physics2011，109，7： | 1 |
| 12 | NOx emission characteristics in rich-lean combustion of hydrogen 显示文摘 | Toshio Shudo Takashi Mizuide | 2002 | JSAE Review2002，23，： | 1 |
| 13 | Identification of monoclonal insulin autoantibodies in insulin autoimmune syndrome associated with HLA-DRB1*0401 显示文摘 | MURAKAMI M MIZUIDE M KASHIMA K | 2000 | Horm Res2000，54，1： | 1 |
| 14 | Identification of monoclonal insulin autoantibodies in insulin autoimmune syndrome associated with HLA-DRB1·0401显示文摘 | Murakami M Mizuide M Kashima K | 2000 | Hrom Res2000，54，： | 1 |
| 15 | Interaction with Smad4 is indispen-sable for suppression of BMP signaling by c-Ski显示文摘 | Takeda M Mizuide M Oka M | | 0，，： | 1 |
| 16 | Identification ofmonoclonal insulin autoantibodies in insulin autoimmune syndrome associated withHLA-DRBI*0401显示文摘 | Murakami M Mizuide M Kashima K | 2000 | Horm Res2000，54，1： | 1 |
| 17 | Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN显示文摘 | Mizuide M Hara T Furuya T | 2003 | J Biol Chem2003，278，1： | 1 |
| 18 | Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN显示文摘 | Mizuide M Hara T Furuya T | 2003 | J Biol Chem2003，278，1： | 1 |
| 19 | Interaction with Smad 4 is indispensable for suppression of BMP signaling by c-Ski显示文摘 | TAKEDA M MIZUIDE M OKA M | 2004 | Mol Biol Cell2004，15，96： | 1 |
| 20 | Solitary pituitary metastasis resulting from pulmonary large cell neuroendocrine carcinoma显示文摘Solitary pituitary metastasis is a rare phenomenon in human neoplasms. We report a case of lung cancer with the initial manifestation of endocrinopathy resulting from pituitary metastasis. The patient's initial diagnosis was a poorly differentiated carcinoma, however, morbid anatomy revealed a definite diagnosis of large cell neuroendocrine carcinoma(LCNEC). Clinical physicians should be aware of potential initial manifestations such as endocrine abnormalities including panhypopituitarism and diabetes insipidus due to solitary pituitary metastasis. This case demonstrates that an endocrine abnormality such as panhypopituitarism could be an initial manifestation of LCNEC. | Takuya Watanabe Kyoichi Kaira Masafumi Mizuide Noriaki Sunaga Nobuyuki Shibusawa Takeshi Hisada Tetsurou Satoh Masatomo Mori Masanobu Yamada | 2014 | World Journal of Respirology2014，4，1： | 0 |
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