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| 1 | Changes in the level of serum liver enzymes after laparoscopic surgery显示文摘AIM: The purpose of this study was to investigate the effectof laparoscopic surgery on liver function in humans and thepossible mechanisms behind such effect.METHODS: Blood samples from 286 patients whounderwent laparoscopic cholecystectomy (LC) and 40patients who underwent open cholecystectomy (OC) weretested for liver function by measuring the level of serumalanine aminotrasferase (ALT) and aspartate aminotrasferase(AST) before and after the operations. The same tests werealso applied to 18 laparoscopic colorectal cancer resection(LCR) patients and 23 open colorectal cancer resection (OCR)patients to determine whether CO2 pneumoperitoneum couldalter the serum liver enzymes.RESULTS: The level of serum ALT and AST increasedsignificantly during the first 48 hours post operations in bothLC and LCR patients. However, no significant change of theserum liver enzymes was detected in both OC and OCRpatients. As a result, there was statistically significantdifference in change of both ALT and AST levels betweenLC and OC patients and LCR and OCR patients, respectively.By the 7th day post operation, the level of both enzymesreturned to normal values in LC, OC and OCR patients exceptLCR patients whose enzymes remained at a higher level.CONCLUSION: Transient elevation of hepatic transaminasesoccurred after laparoscopic surgery. The major causativefactor seemed to be the CO2 pneumoperitoneum. In mostof the laparoscopic surgery patients, the transient elevationof serum liver enzymes showed no apparent clinicalimplications. However, if preoperative liver function was verypoor, laparoscopic surgery may not be the best choice forthe treatment of patients with certain abdominal diseases. | Min Tan Feng-Feng Xu Jun-Shen Peng Dong-Ming Li Liu-Hua Chen Bao-Jun Lv Zhen-Xian Zhao Chen Huang Chao-Xu Zheng Department of General Surgery, the First Affiliated Hospital of Zhong Shah University, 58 Zhongshan 2 Road Guangzhou 510080, Guangdong Province China | 2003 | World Journal of Gastroenterology2003，9，2： | 42 |
| 2 | Trend of China land water storage redistribution at medi- and large-spatial scales in recent five years by satellite gravity observations显示文摘卫星严肃使命提供了的优雅(严肃恢复和气候实验) 学习土地的一个新方法在最近的年里在 medi 空间、长空间的规模浇集体再分配。我们在 2003 ~ 2007 期间用优雅观察在中国估计大陆人水团再分配。结果随增加显示出一些大区域或土地的减少在 Xinjiang Uygur 自治区域在中央北区域,西藏的高原,三个峡区域, Qinghai,四川和 Gansu 省相遇的地方,和 Altun 山区域浇集体存储。在开始的二个区域,水(冰) 集中,是明显的存储正在减少。在以 2.4 cm/a 等价物的线性率的中央北区域减少的水质量浇高度,在五年的时期期间每年等于到 52 亿立方的米,并且浇集体弄空在 Hebei 省是 ∼45 亿立方的米每滥用的地下的水的年每在一样的时期,它与一般水准一致的年浇 40 亿立方的米的集体弄空在最近 Hebei 省估计的 30 年浇资源局。而且,优雅能检测 ∼ 的水团累积在散布超过大约 12 万的区域以内的 5 厘米相等的水高度由于三峡摆平公里在 2003 年 6 月的水坝建设。我们也发现 ∼ 的水团获得在 Qinghai,四川和 Gansu 省相遇的区域的 1.1 cm/a。这显示这些区域的气候在最近的年里一直在变得逐渐地潮湿。 | ZHONG Min DUAN JianBin XU HouZe PENG Peng YAN HaoMing ZHU YaoZhong | 2009 | Chinese Science Bulletin2009，54，5： | 35 |
| 3 | The cloning of 3'-truncated preS/S gene from HBV genomic DNA and its expression in transgenic mice显示文摘INTRODUCTIONHepatitis B virus (HBV) is regarded as one of themain etiologic factors involved in the developmentof human hepatocellular carcinoma (HCC).The open reading frame (orf)of X gene of HBVencoded a transactivating factor is the evidence thatstrongly supported the notion that the X gene ofHBV DNA integrated in HCC genomic DNA couldcontribute to the carcinogenesis of liver cells byactivation of some related cellular genes | Yi Ping Hu~1 Yu Cheng Yao~1 Jian Xiu Li~1 Xin Min Wang~1 Hong Li~2 Zhong Hua Wang~1 Zhang Heng Lei~3 1 Department of Cell Biology,Second Military Medical University,Shanghai 200433,China 2 Department of Biology,Department of Basic Medicine,West-China University of Medical Sciences,Chengdu 610041,China 3 Department of Biology,North Sichuan Medical College,Nanchong 637007,China | 2000 | World Journal of Gastroenterology2000，6，5： | 18 |
| 4 | Genotyping for Kidd, Kell, Duffy, Scianna, and RHCE blood group antigens polymorphisms in Jiangsu Chinese Han显示文摘 | LIU Zhong ZENG Rong CHEN Qing LI Min SHI Guang-yao WEI Peng HUANG Cheng-yin TANG Rong-cai SUN Jun ZHANG Xue-guang | 2012 | Chinese Medical Journal2012，，6： | 18 |
| 5 | A nowcasting model for the prediction of typhoon tracks based on a long short term memory neural network显示文摘It is of vital importance to reduce injuries and economic losses by accurate forecasts of typhoon tracks. A huge amount of typhoon observations have been accumulated by the meteorological department, however, they are yet to be adequately utilized. It is an effective method to employ machine learning to perform forecasts. A long short term memory(LSTM) neural network is trained based on the typhoon observations during 1949–2011 in China's Mainland, combined with big data and data mining technologies, and a forecast model based on machine learning for the prediction of typhoon tracks is developed. The results show that the employed algorithm produces desirable 6–24 h nowcasting of typhoon tracks with an improved precision. | GAO Song ZHAO Peng PAN Bin LI Yaru ZHOU Min XU Jiangling ZHONG Shan SHI Zhenwei | 2018 | Acta Oceanologica Sinica2018，37，5： | 17 |
| 6 | Synthesis of spherical LiNi_(0.8)Co_(0.15)Al_(0.05)O_2 cathode materials for lithium-ion batteries by a co-oxidation-controlled crystallization method显示文摘球形的 Ni0.8Co0.15Al0.05OOH 先锋,由一个 co-oxidation-controlled 结晶化方法准备了,被用来综合 LiNi0.8Co0.15Al0.05O2。获得的 LiNi0.8Co0.15Al0.05O2 材料看了优秀电气化学的性能,与 193.5 mAh/g 的一个起始的分泌物能力和在 50 个周期以后的 95.1% 的能力保留什么时候以在 2.8 和 4.3 V 之间的 0.2 C 率骑车了。 | Wan Min Liu Guo Rong Hu Zhong Dong Peng Ke Du Yan Bing Cao Qiang Liu | 2011 | Chinese Chemical Letters2011，22，9： | 17 |
| 7 | Sea level variations in the South China Sea inferred from satellite gravity,altimetry,and oceanographic data显示文摘Sea level variations(SLVs) can be divided into two major components:the steric SLV and the mass-induced SLV.These two components of SLV in the South China Sea(SCS) are studied by using satellite altimetry,GRACE(Gravity Recovery and Climate Experiment) satellite gravity,and oceanographic data on annual and inter-annual timescales.On the annual timescale,the geographic distribution of mass-induced SLV's amplitude jointly estimated from altimetry and the ECCO(Estimation of the Circulation and Climate of the Ocean) model agrees very well with that from GRACE.GRACE observes obvious seasonal mass-induced SLV in the SCS with annual amplitude of 2.7±0.4 cm,which is consistent with the annual amplitude of 2.7±0.3 cm estimated from the steric-corrected altimetry.On the inter-annual timescales,the mean SLV in the SCS shows a large oscillation,which is mainly caused by the steric effect.The trend of mean SLV inferred from altimetry in the SCS is 5.5±0.7 mm/yr for the period of 1993-2009,which is significantly higher than the global sea level rise rate of 3.3±0.4 mm/yr in the same period.There is no obvious trend signal in the mass-induced SLV detected from GRACE that indicates the water exchange between the SCS and its adjacent seas and land is in balance within the study period. | FENG Wei 1,2,ZHONG Min 1,3 & XU HouZe 1,3 1 State Key Laboratory of Geodesy and Earth’s Dynamics,Institute of Geodesy and Geophysics,Chinese Academy of Sciences,Wuhan 430077,China 2 Graduate University of Chinese Academy of Sciences,Beijing 100049,China 3 Institute of Geophysics,Huazhong University of Science and Technology,Wuhan 430074,China | 2012 | Science China Earth Sciences2012，55，10： | 15 |
| 8 | Expression of lung resistance protein in patients with gastric carcinoma and its clinical significance显示文摘INTRODUCTION The efficacy of chemotherapy in the treatment of cance patients is often hampered by the presence or appearance of multidrug resistance(MDR) of tumor cells. | Zhong Min Liu Nan Hai Shou Xi Hong Jiang | 2000 | World Journal of Gastroenterology2000，6，3： | 15 |
| 9 | Dynamics Analysis of the Baiyun Sag in the Pearl River Mouth Basin,North of the South China Sea显示文摘摘要:Baiyun 下垂是在珍珠河嘴盆的斜坡上发展的深的。它水平地作为合成 graben 发生,并且由二亚 sags 对亚 sags 构成低高举。垂直地,沉积建筑学能被划分成三层,即底部,在中间的差错可锻的拉长层和顶上的 draping 层上的指责的层。sag 的主要 rifting 阶段应当被可锻的扩展描绘并且外壳变瘦。特殊变丑模式可能被归因于事实 Baiyun 下垂位于弱地区,使 sag 成为了一个强烈使变形的区域,由极大地变瘦的岩石圈和活跃 magmatism 描绘了的先存在的转移地区。在 Baiyun 下面的高度升起的披风下垂应该是为可锻的变丑负责的重要机制,它引起了上面的披风的部分融化。Upwelling 到上面的外壳和沉积的层,部分融化材料提供了 extensional 紧张并且引起了非指责的垂直沉淀。岩浆在 rifting 的第一个阶段以后在转移地区下面被收集,并且沿着趋势 NW 基础差错在对对 sag 和 upwelled 的 ENE 和 WSW 部分的扩展垂直的一个方向旁边地转了,在的地方趋势 WNW 砍差错在群发展了。指责的活动和 Baiyun 的沉积历史下垂可能被海洋山脉影响了在 24 妈和海地板在 16 妈附近传播的停止附近跳。 | SUN Zhen ZHONG Zhihong ZHOU Di PANG Xiong HUANG Chunju CHEN Changmin HE Min XU Hehua | 2008 | Acta Geologica Sinica(English Edition)2008，82，1： | 13 |
| 10 | Effects of chromium on the corrosion and electrochemical behaviors of ultra high strength steels显示文摘The effects of chromium on the corrosion and the electrochemical behaviors of ultra high strength steels were studied by the salt spray test and electrochemical methods.The results show that ultra high strength steels remain martensite structures and have anodic dissolution characteristic with an increase of chromium content.There is no typical passive region on the polarization curves of an ultra high strength stainless steel,AerMet 100 steel,and 300M steel.However,chromium improves the corrosion resistance of the stainless steel remarkably.It has the slowest corrosion rate in the salt spray test,one order of magnitude less than that of AerMet 100 and 300M steels.With the increase of chromium content,the polarization resistance becomes larger,the corrosion potential shifts towards the positive direction with a value of 545 mV,and the corrosion current density decreases in electrochemical measures in 3.5wt% NaCl solutions.Because of the higher content of chromium,the ultra high strength stainless steel has a better corrosion resistance than AerMet 100 and 300M steels. | Jin-yan Zhong Min Sun Da-bo Liu Xiao-gang Li Tian-qi Liu | 2010 | International Journal of Minerals,Metallurgy and Materials2010，17，3： | 12 |
| 11 | Data-Driven Based Fault Prognosis for Industrial Systems:A Concise Overview显示文摘Fault prognosis is mainly referred to the estimation of the operating time before a failure occurs,which is vital for ensuring the stability,safety and long lifetime of degrading industrial systems.According to the results of fault prognosis,the maintenance strategy for underlying industrial systems can realize the conversion from passive maintenance to active maintenance.With the increased complexity and the improved automation level of industrial systems,fault prognosis techniques have become more and more indispensable.Particularly,the datadriven based prognosis approaches,which tend to find the hidden fault factors and determine the specific fault occurrence time of the system by analysing historical or real-time measurement data,gain great attention from different industrial sectors.In this context,the major task of this paper is to present a systematic overview of data-driven fault prognosis for industrial systems.Firstly,the characteristics of different prognosis methods are revealed with the data-based ones being highlighted.Moreover,based on the different data characteristics that exist in industrial systems,the corresponding fault prognosis methodologies are illustrated,with emphasis on analyses and comparisons of different prognosis methods.Finally,we reveal the current research trends and look forward to the future challenges in this field.This review is expected to serve as a tutorial and source of references for fault prognosis researchers. | Kai Zhong Min Han Bing Han | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，2： | 12 |
| 12 | Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction显示文摘Zika 病毒(ZIKV ) 的最近的爆发为治疗学加亮迫切需要。朊酶建筑群 NS2B-NS3 在 flaviviral polyprotein 处理期间起必要作用,并且因此代表一个吸引人的药目标。这里,我们开发了裂口酶识别直接指向 flavivirus NS2B-NS3 相互作用的 orthosteric 禁止者的基于互补的高产量的屏蔽试金。由屏蔽一个总数 2 816 同意了并且 investigational 药,我们识别了三个有势力候选人, temoporfin, niclosamide,和 nitazoxanide,,有 nanomolar 力量的 flavivirus NS2B-NS3 相互作用禁止者。显著地,在老鼠的在人的胎盘、神经的祖先房间的大多数有势力化合物, temoporfin,不是仅仅禁止的 ZIKV 复制,而且阻止的导致 ZIKV 的 viremia 和死亡当模特儿。结构的停靠建议 temoporfin 潜在地绑保持批评 NS2B 残余的 NS3 衣袋,因此禁止以一种非竞争的方式处理的 flaviviral polyprotein。当这些药已经在 USA 或另外的国家在另外的指示任何一个为临床的使用被同意了,他们由 ZIKV 和另外的 flaviviruses 为感染的管理代表有希望、容易开发的治疗。 | Zhong Li Matthew Brecher Yong-Qiang Deng Jing Zhang Srilatha Sakamuru Binbin Liu Ruili Huang Cheri A Koetzner Christina A Allen Susan A Jones Haiying Chen Na-Na Zhang Min Tian Fengshan Gao Qishan Lin Nilesh Banavali Jia Zhou Nathan Boles Menghang Xia Laura D Kramer Cheng-Feng Qin Hongmin Li | 2017 | Cell Research2017，27，8： | 11 |
| 13 | Middle-term follow-up results of Pipkin type Ⅳ femoral head fracture patients treated by reconstruction plate and bioabsorbable screws显示文摘 | Shan-Xi Wang Bo-Hua Li Jun Li Fu-Guo Huang Zhou Xiang Gang Zhong Yue Fang Min Yi Xiao-Dan Zhao Lei Liu | 2018 | Chinese Journal of Traumatology2018，21，3： | 11 |
| 14 | High-speed wind tunnel test of the CAE aerodynamic validation model显示文摘For the purpose of establishing and validating aerodynamic performance predictions at transonic Mach numbers, a wind tunnel test was conducted in the High-Speed Tunnel(HST) of the German-Dutch Wind Tunnels. The test article is the aerodynamic validation model from the Chinese Aeronautical Establishment, which is a full-span scale model representation of a business jet aircraft. The wind tunnel test comprised of parallel deployments of balance, pressures, infrared thermography, and model marker measurement techniques. Dedicated investigations with a dummy support were conducted as well, in order to derive and correct for the interference that the support system imposed on the overall model loads. This enabled the establishment of a comprehensive dataset in which the steady overall model loads, the wing load distribution, the state of the wing boundary layer, and the aeroelastic wing shape were quantified for conditions up to and beyond the cruise Mach number of 0.85. | Roy GEBBINK Ganglin WANG Min ZHONG | 2018 | Chinese Journal of Aeronautics2018，31，3： | 11 |
| 15 | Targeted mutagenesis of amino acid transporter genes for rice quality improvement using the CRISPR/Cas9 system显示文摘High grain protein content(GPC) reduces rice eating and cooking quality(ECQ). We generated OsAAP6 and OsAAP10 knockout mutants in three high-yielding japonica varieties and one japonica line using the CRISPR/Cas9 system. Mutation efficiency varied with genetic background in the T_0 generation, and GPC in the T_1 generation decreased significantly,owing mainly to a reduction in glutelin content. Amylose content was down-regulated significantly in some Osaap6 and all Osaap10 mutants. The increased taste value of these mutants was supported by Rapid Visco Analysis(RVA) profiles, which showed higher peak viscosity and breakdown viscosity and lower setback viscosity than the wild type. There were no significant deficiencies in agronomic traits of the mutants. Targeted mutagenesis of OsAAP6 and OsAAP10, especially OsAAP10, using the CRISPR/Cas9 system can rapidly reduce GPC and improve ECQ of rice, providing a new strategy for the breeding cultivars with desired ECQ. | Shiyu Wang Yihao Yang Min Guo Chongyuan Zhong Changjie Yan Shengyuan Sun | 2020 | The Crop Journal2020，8，3： | 11 |
| 16 | Protective effects of baicalin on oxygen/glucose deprivation - and NMDA -induced injuries in rat hippocampal slices显示文摘 | Lu - Ying Liu Er - Qing Wei Yan- Min Zhao Fang - Xue Chen Meng - Ling Wang Wei - Ping Zhang Zhong Chen | 2005 | 中国药理通讯2005，22，4： | 11 |
| 17 | Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A1 receptor-mediated transactivation of epidermal growth factor receptor显示文摘目的: 从中国植物 Paeoniae 根值的 Paeoniflorin 被显示了改善中间的服的动脉在老鼠的导致吸藏的局部缺血。这研究的目的是调查在有教养的老鼠位于 PF 的 neuroprotective 行动下面的机制外皮的神经原。 | Min ZHONG Wan-ling SONG Ye-chun XU Yang YE Lin-yin FENG | 2015 | Acta Pharmacologica Sinica2015，36，3： | 11 |
| 18 | Recent development of a CFD-wind tunnel correlation study based on CAE-AVM investigation显示文摘This paper starts with brief introduction to the open topic of the CFD and wing tunnel correlation study, followed by a description of the Chinese Aeronautical Establishment(CAE) –Aerodynamic Validation Model(AVM) and its wind tunnel test in the German-Dutch Wind tunnels(DNW). The features of the aerodynamic design, the CFD approach, the wind tunnel model fabrication and the experimental techniques are discussed along with the motivation of the CAEDNW workshop on CFD-wind tunnel correlation study. The workshop objective is focused on the interference from the aero-elastic deformation of the wind tunnel model and the model support system to the aerodynamic performance and CFD validations. The four study cases, geometry and mesh preparation of the workshop are introduced. A comprehensive summary of the CFD results from the organizer and the participants is provided. Major observations, both CFD to CFD and CFD to wind tunnel, are identified and summarized. The CFD results of the participants are in good agreement with each other, and with the wind tunnel test data when the wing deformation and a Z-sting system are included in the CFD, indicating the importance of considering such interference at high subsonic Mach number of 0.85. | Jun HUA Sui ZHENG Min ZHONG Ganglin WANG Georg EITELBERG Sinus HEGEN Roy GEBBINK | 2018 | Chinese Journal of Aeronautics2018，31，3： | 10 |
| 19 | Establishment of transgenic mouse harboring hepatitis B virus (adr subtype) genomes显示文摘INTRODUCTIONHepatitis B virus (HBV) belongs to the group ofhepatovirus, a major pathogen of human acute andchronic hepatitis B[1 4], which has a very closeassociation with human hepatocellular carcinoma(HCC)[5-8], For example, a statistical data from ahospital in Shanghai showed that 80% of HCCpatients were positive for HBsAg ( personalcommunication). | Yi Ping Hu1 Wei Jiang Hu1 Wen Chao Zheng2 Jian Xiu Li1 De Shun Dai1 Xin Min Wang1 Shu Zhong Zhang1 Hong Yu Yu3 Wei Sun4 Guang Rong Hao4 1Department of Cell Biology, Second Military Medical University, Shanghai 200433, China2University of Wisconsin, Madison, WI 53705, USA3Department of Pathology, Second Military Medical University, Shanghai 200433, China4Center of laboratory Animals, Second Military Medical University, Shanghai 200433, China | 2001 | World Journal of Gastroenterology2001，7，1： | 9 |
| 20 | Construction of an integrated map and location of a bruchid resistance gene in mung bean显示文摘Bruchid beetle(Callosobruchus chinensis) poses a serious threat to the production and storage of mung bean(Vigna radiata). Mapping bruchid resistance(Br) will provide an important basis for cloning the responsible gene(s) and elucidating its functional mechanism, and will also facilitate marker-assisted selection in mung bean breeding. Here, we report the construction of the genetic linkage groups of mung bean and mapping of the Br1 locus using an RIL population derived from a cross between Berken, a bruchid-susceptible line, and ACC41, a bruchid-resistant line. A total of 560 markers were mapped onto 11 linkage groups,with 38.0% of the markers showing distorted segregation. The lengths of the linkage groups ranged from 45.2 to 117.0 c M with a total coverage of 732.9 c M and an average interval of1.3 c M between loci. Br1 was located on LG9 between BM202(0.7 c M) and Vr2-627(1.7 c M).Based on 270 shared SSR markers, most of the linkage groups were assigned to specific chromosomes. These results should further accelerate the genetic study of this crop. | Lixia Wang Chuanshu Wu Min Zhong Dan Zhao Li Mei Honglin Chen Suhua Wang Chunji Liu Xuzhen Cheng | 2016 | The Crop Journal2016，4，5： | 9 |
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