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| 1 | Low-frequency wide-band hybrid energy harvester based on piezoelectric and triboelectric mechanism显示文摘Recently,hybrid energy harvester has been considered as an attractive potential approach to response the worldwide energy crisis due to the combination of advantages from different harvesting mechanism.In this paper,a novel low-frequency wide-band hybrid energy harvester based on piezoelectric and triboelectric mechanism is presented and systematically studied including structural design,fabrication process,working principle simulation and measurement.With a vibrational excitation,the polyvinylidene fluoride(PVDF) cantilevers will vibrate and impact the polydimethylsiloxane(PDMS) film on the substrate,producing a piezoelectric output as well as a triboelectric output.The structural parameters of each cantilever are optimized using finite element simulation,and the well-designed PVDF cantilevers with controllable PDMS mass not only reduce the device working frequency but also enlarge the bandwidth.Under a sweep-frequency test,three voltage peaks induced by the piezoelectric part are observed at 15,32.5 and 47.5 Hz,with the value of 320,288 and 264 mV,respectively.With the combined triboelectric part,a 20 V peak-peak voltage is generated at 15 Hz.The electrical driving ability of this hybrid energy harvester also has been demonstrated by lighting up a commercial light emitting diode(LED). | HAN MengDi ZHANG XiaoSheng LIU Wen SUN XuMing PENG XuHua ZHANG HaiXia | 2013 | Science China(Technological Sciences)2013，56，8： | 17 |
| 2 | Low frequency wide bandwidth MEMS energy harvester based on spiral-shaped PVDF cantilever显示文摘In this paper,a piezoelectric energy harvester based on spiral-shaped polyvinylidene fluoride(PVDF)cantilever is designed and fabricated for harvesting low frequency vibration energy in the environment.In this design,the spiral-shaped PVDF cantilever is major for lowering the resonant frequency by increasing the length of the cantilever;Copper and silicon proof masses on both sides are working on further decreasing the resonant frequency and widen its bandwidth.Due to the high flexibility of the PVDF cantilever,this device is extremely sensitive to vibration and can harvest weak vibration energy.Both simulation and experimental results have approved that this device can operate at very low frequency which is about 20 Hz and can effectively harvest energy from 15–50 Hz.The peak of the output voltage can reach 1.8 V with the acceleration of 0.2 g.This is a promising harvester for powering the wireless sensors in the future. | LIU Wen HAN MengDi MENG Bo SUN XuMing HUANG XianLiang ZHANG HaiXia | 2014 | Science China(Technological Sciences)2014，57，6： | 13 |
| 3 | FHY3 and FAR1 Integrate Light Signals with the miR156-SPL Module-Mediated Aging Pathway to Regulate Arabidopsis Flowering显示文摘In response to competition for light from their neighbors,shade-intolerant plants flower precociously to ensure reproductive success and survival.However,the molecular mechanisms underlying this key developmental switch are not well understood.Here,we show that a pair of Arabidopsis transcription factors essential for phytochrome A signaling,FAR-RED ELONGATED HYPOCOTYL3(FHY3)and FAR-RED IMPAIRED RESPONSE1(FAR1),regulate flowering time by integrating environmental light signals with the miR156-SPL module-mediated aging pathway.We found that FHY3 and FAR1 directly interact with three flowering-promoting SQUAMOSA-PROMOTER BINDING PROTEIN-LIKE(SPL)transcription factors,SPL3,SPL4,and SPL5,and inhibit their binding to the promoters of several key flowering regulatory genes,including FRUITFUL(FUL),LEAFY(LFY),APETALA1(AP1),and MIR172C,thus downregulating their transcript levels and delaying flowering.Under simulated shade conditions,levels of SPL3/4/5 proteins increase,whereas levels of FHY3 and FAR1 proteins decline,thus releasing SPL3/4/5 from FHY3/FAR1 inhibition to allow activation of FUL,LFY,AP1,and MIR172C and,consequently,early flowering.Taken together,these results unravel a novel mechanism whereby plants regulate flowering time by integrating environmental cues(such as light conditions)and an internal developmental program(the miR156-SPL module-mediated aging pathway). | Yurong Xie Qin Zhou Yongping Zhao Quanquan Li Yang Liu Mengdi Ma Baobao Wang Rongxin Shen Zhigang Zheng Haiyang Wang | 2020 | Molecular Plant2020，13，3： | 8 |
| 4 | No expenditure difference among patients with liver cancer at stageⅠ-ⅣV:Findings from a multicenter cross-sectional study in China显示文摘Objective:The number of liver cancer patients in China accounts for more than half of the world.However,China currently lacks national,multicenter economic burden data,and meanwhile,measuring the differences among different subgroups will be informative to formulate corresponding policies in liver cancer control.Thus,the aim of the study was to measure the economic burden of liver cancer by various subgroups.Methods:A hospital-based,multicenter and cross-sectional survey was conducted during 2012・2014,covering 39 hospitals and 21 project sites in 13 provinces across China.The questionnaire covers clinical information,sociology,expenditure,and related variables.All expenditure data were reported in Chinese Yuan(CNY)using 2014 values.Results:A total of 2,223 liver cancer patients were enrolled,of whom 59.61%were late-stage cases(III-IV),and 53.8%were hepatocellular carcinoma.The average total expenditure per liver cancer patient was estimated as 53,220 CNY,including 48,612 CNY of medical expenditures(91.3%)and 4,608 CNY of non-medical expenditures(8.7%).The average total expenditures in stage I,H,m and stage IV were 52,817 CNY,50,877 CNY,50,678 CNY and 54,089 CNY(P>0.05),respectively.Non-medical expenditures including additional meals,additional nutrition care,transportation,accommodation and hired informal nursing were 1,453 CNY,839 CNY,946 CNY,679 CNY and 200 CNY,respectively.The one-year out-of-pocket expenditure of a newly diagnosed patient was 24,953 CNY,and 77.2%of the patients suffered an unmanageable financial burden.Multivariate analysis showed that overall expenditure differed in almost all subgroups(P<0.05),except for sex,clinical stage,and pathologic type.Conclusions:There was no difference in treatment expenditure for liver cancer patients at different clinical stages,which suggests that maintaining efforts on treatment efficacy improvement is important but not enough.To fiirtherly reduce the overall economic burden from liver cancer,more effort should be given to primary and secondary prevention strategies. | Haike Lei Lin Lei Jufang Shi Yongzhong Wu Ling Liang Huiyao Huang Mei He Fangzhou Bai Maomao Cao Hui Qiu Yuting Wang Chengcheng Liu Jia Du Hong Wang Yan Zhang Mengdi Cao Ji Peng Ni Li Chunfeng Qu Min Dai Wanqing Chen Jie He | 2020 | Chinese Journal of Cancer Research2020，32，4： | 7 |
| 5 | Safety and Efficacy of Physical Thermal Ablation Combined Sorafenib for Hepatocellular Carcinoma:A Meta-analysis显示文摘Background and Aims:To compare the efficacy and safety of physical thermal ablation(PTA),including radiofrequency ablation(RFA)and microwave ablation(MWA),combined with sorafenib and physical thermal ablation alone for the control and treatment of hepatocellular carcinoma(HCC)according to the available literature.Methods:Comprehensive searches were performed on PubMed,Embase,CNKI,the Cochrane Library,China Biomedical Literature Database(known as CBM),Weipu Journal,and Wanfang Database.Meta-analysis was performed using Revman 5.3 software.Results:A total of 15 studies,consisting of 2,227 HCC patients,were selected and included in this meta-analysis.Compared with the RFA-alone group,the patients in the RFA+sorafenib group had longer 1-,2-,and 3-year overall survival(all p<0.05),better overall efficacy(p<0.0001),longer radiofrequency interval(p<0.001),and lower 2-year recurrence rate(p=0.02).The 1-year overall survival(p=0.003)and overall efficacy(p=0.002)of the MWA+sorafenib group were also higher than those of the MWA-alone group.The incidences of adverse reactions in the RFA+sorafenib group,such as hand-foot skin reactions(p<0.001),diarrhea and constipation(p=0.0001),hypertension(p=0.009),and alopecia(p<0.001),were significantly higher than those in the RFA-alone group.Conclusions:RFA or MWA combined with sorafenib has produced a better therapeutic effect on HCC than physical thermal ablation alone;however,adverse reactions have been obvious.It is necessary to evaluate the safety of combination therapy,and pay close attention to the adverse reactions that develop in patients. | Mengdi Jin Qiong Yu Yahui Liu Weiling Xu Xueqi Fu Bai Ji | 2021 | Journal of Clinical and Translational Hepatology2021，9，2： | 6 |
| 6 | Overexpressed Cyclin D1 and CDK4 proteins are responsible for the resistance to CDK4/6 inhibitor in breast cancer that can be reversed by PI3K/mTOR inhibitors显示文摘CDK4/6 inhibitors are the standard treatment in advanced HR+/HER2-breast cancer patients.Nevertheless,the resistance to CDK4/6 inhibitors is inevitable and the strategies to overcome resistance are of great interest.Here,we show that the palbociclibresistant breast cancer cells expressed significantly higher levels of Cyclin D1 and CDK4 proteins because of upregulated protein synthesis.Silencing Cyclin D1 or CDK4 led to cell cycle arrest while silencing Cyclin E1 or CDK2 restored the sensitivity to palbociclib.Furthermore,PI3K/mTOR pathway was hyper-activated in palbociclib-resistant cells,leading to more phosphorylated 4E-BP1 and higher levels of Cyclin D1 and CDK4 translation.Targeting PI3K/mTOR pathway with a specific PI3Kαinhibitor(BYL719)or an mTOR inhibitor(everolimus)reduced the protein levels of Cyclin D1 and CDK4,and restored the sensitivity to palbociclib.The tumor samples expressed significantly higher levels of Cyclin D1,CDK4,p-AKT and p-4E-BP1 after progression on palbociclib treatment.In conclusion,our findings suggest that overexpressed Cyclin D1 and CDK4 proteins lead to the resistance to CDK4/6 inhibitor and PI3K/mTOR inhibitors are able to restore the sensitivity to CDK4/6 inhibitors,which provides the biomarker and rationale for the combinational use of CDK4/6 inhibitors and PI3K/mTOR inhibitors after CDK4/6 inhibitor resistance in breast cancer. | Zijie Cai Jingru Wang Yudong Li Qianfeng Shi Liang Jin Shunying Li Mengdi Zhu Qi Wang Lok Lam Wong Wang Yang Hongna Lai Chang Gong Yandan Yao Yujie Liu Jun Zhang Herui Yao Qiang Liu | 2023 | Science China(Life Sciences)2023，66，1： | 4 |
| 7 | Deficient Rnf43 potentiates hyperactive Kras-mediated pancreatic preneoplasia initiation and malignant transformation显示文摘Background:Largely due to incidental detection,asymptomatic pancreatic cystic le-sions(PCLs)have become prevalent in recent years.Among them,intraductal papillary mucinous neoplasm(IPMN)infrequently advances to pancreatic ductal adenocarcinoma(PDAC).Conservative surveillance versus surgical intervention is a difficult clinical decision for both caregivers and PCL patients.Because RNF43 loss-of-function mutations and KRAS gain-of-function mutations concur in a subset of IPMN and PDAC,their biological significance and therapeutic potential should be elucidated.Methods:Pancreatic Rnf43 knockout and Kras activated mice(Rnf43^(−/−);Kras^(G12D))were generated to evaluate their clinical significance in pancreatic pre-neoplastic initiation and malignant transformation.Results:Loss of Rnf43 potentiated the occurrence and severity of IPMN and PDAC in oncogenic Kras mice.The Wnt/β-catenin signaling pathway was activated in pan-creatic Kras^(G12D)and Rnf43 knockout mice and the PORCN inhibitor LGK974 blocked pancreatic IPMN initiation and progression to PDAC accordingly.Conclusions:Rnf43 is a tumor suppressor in the prevention of pancreatic malignant transformation.This genetically reconstituted autochthonous pancreatic Rnf43^(−/−);Kras^(G12D)preclinical cancer model recapitulates the pathological process from pancreatic cyst to cancer in humans and can be treated with inhibitors of Wnt/β-catenin signaling.Since the presence of RNF43 and KRAS mutations in IPMNs predicts future development of advanced neoplasia from PCLs,patients with these genetic anomalies warrant surveillance,surgery,and/or targeted therapeutics such as Wnt/β-catenin inhibitors. | Xian Zhou Zhichao Sun Mengdi Zhang Xiaoyu Qu Shuhui Yang Lianmei Wang Yanling Jing Li Li Weiwei Deng Fangming Liu Jin Di Jie Chen Jian Wu Hongbing Zhang | 2022 | Animal Models and Experimental Medicine2022，5，1： | 3 |
| 8 | High entropy spinel oxide for efficient electrochemical oxidation of ammonia显示文摘Ammonia has emerged as a promising energy carrier owing to its carbon neutral content and low expense in long-range transportation.Therefore,development of a specific pathway to release the energy stored in ammonia is therefore in urgent demand.Electrochemical oxidation provides a convenient and reliable route to attain efficient utilization of ammonia.Here,we report that the high entropy(Mn,Fe,Co,Ni,Cu)_(3)O_(4)oxides can achieve high electrocatalytic activity for ammonia oxidation reaction(AOR)in non-aqueous solutions.The AOR onset overpotential of(Mn,Fe,Co,Ni,Cu)_(3)O_(4)is 0.70 V,which is nearly 0.2 V lower than that of their most active single metal cation counterpart.The mass spectroscopy study reveals that(Mn,Fe,Co,Ni,Cu)_(3)O_(4)preferentially oxidizes ammonia to environmentally friendly diatomic nitrogen with a Faradic efficiency of over 85%.The Xray photoelectron spectroscopy(XPS)result indicates that the balancing metal d-band of Mn and Cu cations helps retain a longlasting electrocatalytic activity.Overall,this work introduces a new family of earth-abundant transition metal high entropy oxide electrocatalysts for AOR,thus heralding a new paradigm of catalyst design for enabling ammonia as an energy carrier. | Shi He Vasishta Somayaji Mengdi Wang Seung-Hoon Lee Zhijia Geng Siyuan Zhu Peter Novello Chakrapani V.Varanasi Jie Liu | 2022 | Nano Research2022，15，6： | 3 |
| 9 | Effects of phosvitin phosphopeptide-Ca complex prepared by efficient enzymatic hydrolysis on calcium absorption and bone deposition of mice显示文摘Phosvitin(PV)was treated with high-temperature,mild pressure(HTMP),and enzyme combination,and then phosvitin phosphopeptides-calcium(PPP-Ca)complexes were prepared.The low-calcium specific pathogen free-Kunming(SPF-KM)mice were used to determine the effect of PPP-Ca complexes on intestinal calcium absorption and their utilization for bone formation.The serum calcium content was the highest with the HTMP-Enz-PPP-Ca treatment(2.19 mmol/L),and it significantly down-regulated the abnormal elevation of serum alkaline phosphatase(AKP)caused by calcium deficiency.The low-calcium control group had the lowest calcium deposited to the femur(80.41 mg/g)and the lowest femur bone mineral density(BMD)(0.17 g/cm^(3)),while HTMP-Enz-PPP-Ca significantly improved bone calcium content(94.33 mg/g)and BMD(0.29 g/cm^(3)).The micro-computed tomography(MCT)images showed that the femur with the normal control,PV-Ca,and HTMP-Enz-PPP-Ca treatments had a more compact,complete,and thicker trabecular network than the low-calcium and CaCl_(2)treatments.These results indicated that the organic calcium(HTMP-Enz-PPP-Ca)promoted calcium absorption and bone deposition,and the effect of HTMP-Enz-PPP-Ca was better than the inorganic CaCl_(2). | Mengdie Zhao Dong Uk Ahn Songming Li Wei Liu Shengwei Yi Xi Huang | 2022 | Food Science and Human Wellness2022，11，6： | 3 |
| 10 | Genetic Interactions Reveal that Speci c Defects of Chloroplast Translation are Associated with the Suppression of var2-Mediated Leaf Variegation显示文摘Arabidopsis thaliana L.yellow variegated(var2)mutant is defective in a chloroplast FtsH family metalloprotease,AtFtsH2/VAR2,and displays an intriguing green and white leaf variegation.This unique var2 mediated leaf variegation offers a simple yet powerful tool for dissecting the genetic regulation of chloroplast development.Here,we report the isolation and characterization of a new var2suppressor gene,SUPPRESSOR OF VARIEGATION8(SVR8),which encodes a putative chloroplast ribosomal large subunit protein,L24.Mutations in SVR8suppress var2leaf variegation at ambient temperature and partially suppress the cold induced chlorosis phenotype of var2.Loss of SVR8 causes unique chloroplast rRNA processing defects,particularly the 23S–4.5S dicistronic precursor.The recovery of the major abnormal processing site in svr823S–4.5S precursor indicate that it does not lie in the same position where SVR8/L24 binds on the ribosome.Surprisingly,we found that the loss of a chloroplast ribosomal small subunit protein,S21,results in aberrant chloroplast rRNA processing but not suppression of var2variegation.These ndings suggest that the disruption of speci c aspects of chloroplast translation,rather than a general impairment in chloroplast translation,suppress var2variegation and the existence of complex genetic interactions in chloroplast development. | Xiayan Liu Mengdi Zheng Rui Wang Ruijuan Wang Lijun An Steve R.Rodermel Fei Yu | 2013 | Journal of Integrative Plant Biology2013，55，10： | 3 |
| 11 | Design and performance evaluation of additively manufactured composite lattice structures of commercially pure Ti(CP-Ti)显示文摘Ti alloys with lattice structures are garnering more and more attention in the field of bone repair or regeneration due to their superior structural,mechanical,and biological properties.In this study,six types of composite lattice structures with different strut radius that consist of simple cubic(structure A),body-centered cubic(structure B),and edge-centered cubic(structure C)unit cells are designed.The designed structures are firstly simulated and analysed by the finite element(FE)method.Commercially pure Ti(CP-Ti)lattice structures with optimized unit cells and strut radius are then fabricated by selective laser melting(SLM),and the dimensions,microtopography,and mechanical properties are characterised.The results show that among the six types of composite lattice structures,combined BA,CA,and CB structures exhibit smaller maximum von-Mises stress,indicating that these structures have higher strength.Based on the fitting curves of stress/specific surface area versus strut radius,the optimized strut radius of BA,CA,and CB structures is 0.28,0.23,and 0.30 mm respectively.Their corresponding compressive yield strength and compressive modulus are 42.28,30.11,and 176.96 MPa,and 4.13,2.16,and 7.84 GPa,respectively.The CP-Ti with CB unit structure presents a similar strength and compressive modulus to the cortical bone,which makes it a potential candidate for subchondral bone restorations. | Wei Xu Aihua Yu Xin Lu Maryam Tamaddon Mengdi Wang Jiazhen Zhang Jianliang Zhang Xuanhui Qu Chaozong Liu Bo Su | 2021 | Bioactive Materials2021，6，5： | 2 |
| 12 | A cubic triboelectric generator as a self-powered orientation sensor显示文摘Recently, triboelectric generator(TEG) has attracted a lot of attention due to its high output voltage and low-cost fabrication process. Here, a novel cubic TEG box is designed, which has separated electrodes on different surfaces. Thanks to the specially designed structure, it can scavenge vibration energy from all directions. Firstly the device is investigated through finite element method(FEM) simulation. Then the device is evaluated by experiments. The measuremental results show that this device can generate an amount of 25 n C charge during once shake by charging a 10 n F capacitor. Besides, an output voltage about 100 V is obtained, which is able to directly light up several light-emitting diodes(LEDs) simultaneously. At last, the device is utilized as a self-powered orientation sensor, which shows explicit directivity. This work extends the applications of TEG for ambient vibration energy harvesting techniques and the self-powered orientation sensor. | QIU GuoLin LIU Wen HAN MengDi CHENG XiaoLiang MENG Bo SMITHA Ankanahalli Shankaregowda ZHAO JiangMing ZHANG HaiXia | 2015 | Science China(Technological Sciences)2015，58，5： | 2 |
| 13 | Anti-arthritic effects of microneedling with bee venom gel显示文摘Objective:To combine with transdermal drug delivery using microneedle to simulate the bee venom therapy to evaluate the permeation of bee venom gel.Methods:In this study,the sodium urate and LPS were used on rats and mice to construct the model.Bee venom gelemicroneedle combination effect on the model is to determine the role of microneedle gel permeation by observing inflammation factors.Results:Compared with the model group,the bee venom gelemicroneedle combination group can reduce the level of serum nitric oxide of the acute gouty inflammation model caused by sodium urate,and on LPS induced mouse model of acute inflammation effect and the micro.Conclusions:Bee venom can significantly suppress the occurrence of gouty arthritis inflammation in rats and mice LPS inflammatory reaction.Choose the 750 mm microneedle with 10N force on skin about 3 minutes,bee venom can play the optimal role,and the anti-inflammatory effect is obvious.Microneedles can promote the percutaneous absorption of the active macromolecules bee venom gel. | Mengdi Zhao Jie Bai Yang Lu Shouying Du Kexin Shang Pengyue Li Liu Yang Boyu Dong Ning Tan | 2016 | Journal of Traditional Chinese Medical Sciences2016，3，4： | 2 |
| 14 | Antioxidant and ACE inhibitory activities of peptides prepared from adzuki bean by semi-solid enzymatic hydrolysis显示文摘In this study,adzuki bean peptides were prepared by semi-solid enzymatic hydrolysis(SEH)and their antioxidant and Angiotensin-I-converting enzyme(ACE)inhibitory activities and internal absorption were studied.By modifying different enzymatic hydrolysis times and enzyme additions,the optimal enzymatic hydrolysis condition for SEH could be obtained as adzuki bean powder:water=4:1(w/w),alcalase:neutrase=2:1(w/w),enzyme addition 3.75%(w/w),4 h enzymatic hydrolysis at 50℃ and pH=8.Within these hydrolysis conditions,the content of adzuki bean peptides was 11.37%,the OH−scavenging rate of 1 mg/mL peptides was 72.75%,the total antioxidant capacity was 0.88±0.02 mmol/L FeSO4,the ACE inhibition rate was 77.49%.In vivo absorption test proved that the peptides prepared by SEH were absorbed faster and exhibited higher antioxidant activity compared with liquid enzymatic hydrolysis.In conclusion,the process of SEH can improve not only the efficiency of hydrolysis,but also the antioxidant and ACE inhibitory activity as well as the internal absorption of adzuki bean peptides. | Mengdi Cao Wenhui Li He Li Jian Zhang Yu Liu Xinqi Liu | 2022 | Food Bioscience2022，47，3： | 2 |
| 15 | Zn/Sr dual ions-collagen co-assembly hydroxyapatite enhances bone regeneration through procedural osteo-immunomodulation and osteogenesis显示文摘The immune microenvironment induced by biomaterials played vital roles in bone regeneration.Hydroxyapatite(HA)and its ion-substituted derivates represent a large class of core inorganic materials for bone tissue engineering.Although ion substitution was proved to be a potent way to grant HA more biological functions,few studies focused on the immunomodulatory properties of ion-doped HA.Herein,to explore the potential osteoimmunomodulatory effects of ion-doped HA,zinc and strontium co-assembled into HA through a collagen template biomimetic way(ZnSr-Col-HA)was successfully achieved.It was found that ZnSr-Col-HA could induce a favorable osteo-immune microenvironment by stimulating macrophages.Furthermore,ZnSr-Col-HA demonstrated a procedural promoting effect on osteogenic differentiation of bone marrow mesenchymal stem cells(BMSCs)in vitro.Specifically,the osteo-immune microenvironment acted as a dominant factor in promoting osteogenic gene expressions at the early stage through OSM signal pathway.Whereas the direct stimulating effects on BMSCs by Zn^(2+)/Sr^(2+) were more effectively at the later stage with Nfatc1/Maf and Wnt signals activated.In vivo study confirmed strong promoting effects of ZnSr-Col-HA on critical-sized cranial defect repair.The current study indicated that such a combined biomaterial design philosophy of dual ion-doping and biomimetic molecular co-assembly to endow HA applicable osteoimmunomodulatory characteristics might bring up a new cutting-edge concept for bone regeneration study. | Zhenyu Zhong Xiaodan Wu Yifan Wang Mengdie Li Yan Li XuLong Liu Xin Zhang Ziyang Lan Jianglin Wang Yingying Du Shengmin Zhang | 2022 | Bioactive Materials2022，7，4： | 2 |
| 16 | QTL mapping of quality traits in peanut using whole-genome resequencing显示文摘Oil and protein content and fatty acid composition are quality traits in peanut.Elucidating the genetic mechanisms underlying these traits may help researchers to obtain improved cultivars by molecular breeding.Whole-genome resequencing of a recombinant inbred population of 318 lines was performed to construct a high-density linkage map and identify QTL for peanut quality.The map,containing 4561 bin markers,covered 2032 c M with a mean marker density of 0.45 c M.A total of 110 QTL for oil and protein content,and fatty acid composition were mapped on the 18 peanut chromosomes.The QTL q A05.1 was detected in four environments and showed a major phenotypic effect on the contents of oil,protein,and six fatty acids.The genomic region spanned by q A05.1,corresponding to a physical interval of approximately 1.5 Mb,contains two SNPs polymorphic between the parents that could cause missense mutations.The two SNP sites were employed as KASP markers and validated using lines with extremely high and low oil contents.These sites may be useful in the marker-assisted breeding of peanut cultivars with high oil contents. | Ziqi Sun Feiyan Qi Hua Liu Li Qin Jing Xu Lei Shi Zhongxin Zhang Lijuan Miao Bingyan Huang Wenzhao Dong Xiao Wang Mengdi Tian Jingjing Feng Ruifang Zhao Xinyou Zhang Zheng Zheng | 2022 | The Crop Journal2022，10，1： | 2 |
| 17 | Wearable and flexible electrochemical sensors for sweat analysis:a review显示文摘Flexible wearable sweat sensors allow continuous,real-time,noninvasive detection of sweat analytes,provide insight into human physiology at the molecular level,and have received significant attention for their promising applications in personalized health monitoring.Electrochemical sensors are the best choice for wearable sweat sensors due to their high performance,low cost,miniaturization,and wide applicability.Recent developments in soft microfluidics,multiplexed biosensing,energy harvesting devices,and materials have advanced the compatibility of wearable electrochemical sweat-sensing platforms.In this review,we summarize the potential of sweat for medical detection and methods for sweat stimulation and collection.This paper provides an overview of the components of wearable sweat sensors and recent developments in materials and power supply technologies and highlights some typical sensing platforms for different types of analytes.Finally,the paper ends with a discussion of the challenges and a view of the prospective development of this exciting field. | Fupeng Gao Chunxiu Liu Lichao Zhang Tiezhu Liu Zheng Wang Zixuan Song Haoyuan Cai Zhen Fang Jiamin Chen Junbo Wang Mengdi Han Jun Wang Kai Lin Ruoyong Wang Mingxiao Li Qian Mei Xibo Ma Shuli Liang Guangyang Gou Ning Xue | 2023 | Microsystems & Nanoengineering2023，9，1： | 2 |
| 18 | Investigation and characterization of an arc-shaped piezoelectric generator显示文摘A novel arc-shaped piezoelectric generator based on flexible PVDF thin film is presented and systemically studied.With a periodical external force,the generator can produce peak voltage of 45.6 V and peak power of 30.7μW.The maximum power density reaches 38.4μW/cm3with a 4 cm×2 cm×100μm device,at the optimum load resistance of 33.33 MOhm.The influence of frequency,size dimension and load resistance are investigated through experimental measurements.With this high output arc-shaped generator,capacitors can be effectively charged and three commercial LEDs have been directly lighted without any energy storage unit. | HAN MengDi LIU Wen ZHANG XiaoSheng MENG Bo ZHANG HaiXia | 2013 | Science China(Technological Sciences)2013，56，11： | 2 |
| 19 | Insights into the phenomenon of an explosive growth and sharp decline in haze:A case study in Beijing显示文摘A severe haze episode occurred in winter in the North China Plain(NCP),and the phenomenon of an explosive growth and sharp decline in PM2.5(particulate matter with an aerodynamic diameter equal to or less than 2.5μm)concentration was observed.To study the systematic causes for this phenomenon,comprehensive observations were conducted in Beijing from November 26 to December 2,2015;during this period,meteorological parameters,LIDAR data,and the chemical compositions of aerosols were determined.The haze episode was characterized by rapidly varying PM2.5 concentration,and the highest PM2.5 concentration reached 667μg/m3.During the haze episode,the NCP was dominated by a weak high-pressure system and continuously low PBL(planetary boundary layer)heights,which are unfavorable conditions for the diffusion of pollutants.The large increases in the concentrations of SNA(SO42-,NO3-and NH4+)during the haze implied that the formation of SNA was the largest contribution.Water vapor also played a vital role in the formation of haze by promoting the chemical transformation of secondary pollutants,which led to higher PM2.5 concentrations.The spatial distributions of PM2.5 in Beijing at different times and the backward trajectories of the air masses also indicated that pollutants from surrounding provinces in particular,contributed to the higher PM2.5concentration. | Wenguang Li Xingang Liu Yuanhang Zhang Qinwen Tan Miao Feng Mengdi Song Lirong Hui Yu Qu Junling An Haokai Gao | 2019 | Journal of Environmental Sciences2019，31，10： | 1 |
| 20 | Springless Cubic Harvester for Converting Three Dimensional Vibration Energy显示文摘 | Mengdi Han Wen Liu Bo Meng | 2014 | International Conference on MEMS2014，，： | 1 |
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