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| 1 | High-Efficiency Genome Editing in Arabidopsis Using YAO Promoter-Driven CRISPR/Cas9 System显示文摘 | Yan, Liuhua Wei, Shaowei Wu, Yaorong Hu, Ruolan Li, Hongju Yang, Weicai Xie, Qi | 2015 | Molecular Plant2015，8，12： | 50 |
| 2 | Correlative Mechanism of Hydraulic-mechanical Property in Cemented Paste Backfill显示文摘Hydraulic characteristic is a good indication of binder hydration, which determines the strength development of cemented paste backfill(CPB). Therefore, the hydraulic characteristic should be communicated with the mechanical property to provide an advanced knowledge that can help mine workers make a rational strategy and reduce the mining cycle. An experimental program was performed to obtain the hydraulic(monitored by suction and volumetric water content) and mechanical properties(unconfined compressive strength(UCS) test) of CPB at the 28 days curing age. According to the monitoring and testing results, the relationships between the hydration reaction rate and volumetric water content(VWC), suction and VWC, suction and UCS were established. The hydration degree showed a liner rise as the VWC decreased. Curves of the VWC and UCS were featured with a nonlinear reduction and nonlinear growth(both are exponential functions) as the suction rising, respectively. These established relationships validated the strong correlative mechanism of hydraulic and mechanics behavior for CPB. Also, the results of the present research indicated that the hydraulic characteristics and mechanical property were strongly coupled. These correlations and couplings will be of great importance to understand the hardening process of CPB and bring to a safe CPB field operation. | 王勇 吴爱祥 WANG Shaoyong WANG Hongjiang YANG Liuhua WANG Yiming RUAN Zhu'en | 2017 | Journal of Wuhan University of Technology(Materials Science)2017，32，3： | 3 |
| 3 | Alterations in mRNA expression of steroid receptors and heat shock proteins in the liver of rare minnow (Grobiocypris rarus) exposed to atrazine and p,p'-DDE 显示文摘 | Yang Liuhua Zha Jinmiao Zhang Xiaoyan | 2010 | Aquatic Toxicology2010，98，4： | 1 |
| 4 | Clinical surgical departments of medical performance evaluation method显示文摘 | Yangjian Nan Yang Liuhua | 2008 | China''s medical record2008，9，6： | 1 |
| 5 | Improved methodology for efficient establishment of the myocardial ischemia-reperfusion model in pigs through the median thoracic incision显示文摘To investigate the feasibility and effectiveness of establishing porcine ischemia-reperfusion models by ligating the left anterior descending(LAD)coronary artery,we first randomly divided 16 male Bama pigs into a sham group and a model group.After anesthesia,we separated the arteries and veins.Subsequently,we rapidly located the LAD coronary artery at the beginning of its first diagonal branch through a mid-chest incision.Then,we loosened and released the ligation line after five minutes of pre-occlusion.Finally,we ligated the LAD coronary artery in situ two minutes later and loosened the ligature 60 min after ischemia.Compared with the sham group,electrocardiogram showed multiple continuous lead ST-segment elevations,and ultrasound cardiogram showed significantly lower ejection fraction and left ventricular fractional shortening at one hour and seven days post-operation in the model group.Twenty-four hours after the operation,cardiac troponin T and creatine kinase-MB isoenzyme levels significantly increased in the model group,compared with the sham group.Hematoxylin and eosin staining showed the presence of many inflammatory cells infiltrating the interstitium of the myocardium in the model group but not in the sham group.Masson staining revealed a significant increase in infarct size in the ischemia/reperfusion group.All eight pigs in the model group recovered with normal sinus heart rates,and the survival rate was 100%.In conclusion,the method can provide an accurate and stable large animal model for preclinical research on ischemia/reperfusion with a high success rate and homogeneity of the myocardial infarction area. | Liuhua Zhou Jiateng Sun Tongtong Yang Sibo Wang Tiankai Shan Lingfeng Gu Jiawen Chen Tianwen Wei Di Zhao Chong Du Yulin Bao Hao Wang Xiaohu Lu Haoliang Sun Meng Lv Di Yang Liansheng Wang | 2023 | The Journal of Biomedical Research2023，37，4： | 1 |
| 6 | Urban Air Pollution May Enhance COVID-19 Case-Fatality and Mortality Rates in the United States显示文摘BACKGROUND The novel human coronavirus disease 2019(COVID-19)pandemic has claimed more than 600,000 lives worldwide,causing tremendous public health,social,and economic damages.Although the risk factors of COVID-19 are still under investigation,environmental factors,such as urban air pollution,may play an important role in increasing population susceptibility to COVID-19 pathogenesis.METHODS We conducted a cross-sectional nationwide study using zero-inflated negative binomial models to estimate the association between longterm(2010–2016)county-level exposures to NO2,PM2.5,and O3 and county-level COVID-19 case-fatality and mortality rates in the United States.We used both single-and multi-pollutant models and controlled for spatial trends and a comprehensive set of potential confounders,including state-level test positive rate,county-level health care capacity,phase of epidemic,population mobility,population density,sociodemographics,socioeconomic status,race and ethnicity,behavioral risk factors,and meteorology.RESULTS From January 22,2020,to July 17,2020,3,659,828 COVID-19 cases and 138,552 deaths were reported in 3,076 US counties,with an overall observed case-fatality rate of 3.8%.County-level average NO2 concentrations were positively associated with both COVID-19 case-fatality rate and mortality rate in single-,bi-,and tri-pollutant models.When adjusted for co-pollutants,per interquartile-range(IQR)increase in NO2(4.6 ppb),COVID-19 case-fatality rate and mortality rate were associated with an increase of 11.3%(95%CI 4.9%–18.2%)and 16.2%(95%CI 8.7%–24.0%),respectively.We did not observe significant associations between COVID-19 case-fatality rate and long-term exposure to PM2.5 or O3,although per IQR increase in PM2.5(2.6 mg/m3)was marginally associated,with a 14.9%(95%CI 0.0%–31.9%)increase in COVID-19 mortality rate when adjusted for co-pollutants.DISCUSSION Long-term exposure to NO2,which largely arises from urban combustion sources such as traffic,may enhance susceptibility to severe COVID-19 outcomes,independent of long-termPM2.5 and O3 exposure.The results support targeted public health actions to protect residents from COVID-19 in heavily polluted regions with historically high NO2 levels.Continuation of current efforts to lower traffic emissions and ambient air pollution may be an important component of reducing population-level risk of COVID-19 case fatality and mortality. | Donghai Liang Liuhua Shi Jingxuan Zhao Pengfei Liu Jeremy A.Sarnat Song Gao Joel Schwartz Yang Liu Stefanie T.Ebelt Noah Scovronick Howard H.Chang | 2020 | The Innovation2020，1，3： | 1 |
| 7 | Study on Mechanical Properties of High Fine Silty Basalt Fiber Shotcrete Based on Orthogonal Design显示文摘In order to improve the comprehensive utilization rate of highfines sand(HFS)produced by the mine,full solid waste shotcrete(HFS-BFRS)was prepared with HFS asfine aggregate in cooperation with basaltfiber(BF).The strength growth characteristics of HFS-BFRS were analyzed.And thefitting equation of compressive strength growth characteristics of HFS-BFRS under the synergistic effect of multiple factors was given.And based on the orthogonal experimental method,the effects on the compressive strength,splitting tensile strength andflex-ural strength of HFS-BFRS under the action of different levels of influencing factors were investigated.The effect of three factors on the mechanical properties of HFS-BFRS,3,and 28 d,respectively,was revealed by choosing the colloidal sand ratio(C/H),basaltfiber volume fraction(BF Vol)and naphthalene high-efficiency water reducing agent(FDN)as the design variables,combined with indoor tests and theoretical analysis.The results show that the sensitivity of the three factors on compressive strength andflexural strength is C/H>FDN>BF Vol,and split-ting tensile strength is BF Vol>FDN>C/H.Finally,thefitting ratio of HFS-BFRS was optimized by the factor index method,and the rationality was verified by thefield test.For thefluidity of HFS-BFRS,the slump can be improved by 139%under the action of 1.2%FDN,which guarantees the pump-ability of HFS-BFRS. | Jinxing Wang Yingjie Yang Xiaolin Yang Huazhe Jiao Qi Wang Liuhua Yang Jianxin Yu Fengbin Chen | 2023 | Journal of Renewable Materials2023，11，8： | 0 |
| 8 | Synergizing high valence metal sites and amorphous/crystalline interfaces in electrochemical reconstructed CoFeOOH heterostructure enables efficient oxygen evolution reaction显示文摘Cobalt hydroxide nanosheet is among the most popular oxygen evolution reaction(OER)catalyst yet still suffers from sluggish catalytic kinetics,limited activity,and poor stability.Here,an efficient in situ electrochemical reconstructed CoFe-hydroxides derived OER electrocatalyst was reported.The introduction of Fe promoted the transformation of Co^(2+)into Co^(3+)in CoFehydroxides nanosheet,along with the formation of abundant amorphous/crystalline interfaces.Thanks for the retained nanosheet microstructure,high valence Co^(3+)and Fe^(3+)species,and the amorphous/crystalline heterostructure interfaces,the as-designed electrochemical reconstructed CoFeOOH nanosheet/Ni foam(CoFeOOHNS/NF)electrode delivers 100 mA·cm^(−2) in alkaline at an overpotential of 275 mV and can stably electrocatalyze water oxidation for at least 35 h at 100 mA·cm^(−2).Meanwhile,the alkaline full water splitting electrolyzer achieves a current density of 10 mA·cm^(−2) only at 1.522 V for CoFeOOHNS/NF‖Pt/C/NF,which is much lower than that of Ru/C/NF‖Pt/C/NF(1.655 V@10 mA·cm^(−2)).This work paves the way for in-situ synergetic modification engineering of electrochemical active components. | Xiangjian Liu Rui Liu Jinming Wang Yarong Liu Liuhua Li Wenxiu Yang Xiao Feng Bo Wang | 2022 | Nano Research2022，15，10： | 0 |
| 9 | Systematic review of mixing technology for recycling waste tailings as cemented paste backfill in mines in China显示文摘The development of industry is inseparable from the support of mining.However,mining processes consume a large amount of energy,and increased tailing emissions can have a significant impact on the environment.In the past few decades,the mining industry developed many technologies that are related to mineral energy management,of which cemented paste backfill(CPB)is one of the representative technologies.CPB has been successfully applied to mine ground control and tailings management.In CPB technology,the mixing process is the key to achieving materials with good final quality and controlled properties.However,in the preparation process,the mixed homogeneity of the CPB is difficult to achieve because of fine tailings,high solid volume fraction,and high viscosity.Most research focused on the effect of mixing ingredients on CPB properties rather than on the preparation process of the CPB.Therefore,improving the performance and reducing the production cost of CPB by optimizing the mixing process are important.This review summarizes the current studies on the mixing technology of CPB and its application status in China.Then,it compares the advantages and disadvantages of multiple mixing equipment and discusses the latest results and research hotspots in paste preparation.Finally,it concludes the challenges and development trends of mixing technology on the basis of the relevant application cases in China to promoting cement-based material mixing technology development. | Liuhua Yang Jincang Li Hongbin Liu Huazhe Jiao Shenghua Yin Xinming Chen Yang Yu | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，8： | 0 |
| 10 | Study on Strength Reduction Law and Meso-Crack Evolution of Lower Layered Cemented Tailings Backfill显示文摘The green disposal of tailings solid waste is a problem to be solved in mine production.Cemented tailings filling stoping method can realize the dual goals of solid waste resource utilization and mined-out area reduction.However,the volume of the mined-out area of the open-pit method is larger than the filling capacity,resulting in the complex stratification of the underground backfill,and the strength of the backfill cannot meet the requirements.In this paper,according to the delamination situation,the specimens of horizontal and inclination angle layered cemented tailings backfill(LCTB)is made for a uniaxial compression test,and the failure process of delamination backfill is reduced by PFC.The results show that the corresponding reduction factorφof horizontal LCTB is 0.560–0.932,and the correspondingφvalue of inclination angle LCTB is 0.338–0.772.The failure mode of backfill in different layers is mainly manifested as a tensile failure.The PFC numerical simulation results are consistent with laboratory test results,which verifies the correctness of backfill failure.The research results provide a reliable theoretical basis for the strength design of backfill in goaf,which is of great significance for solid waste utilization and environmental protection. | Huazhe Jiao Wenxiang Zhang Yunfei Wang Xinming Chen Liuhua Yang Yangyang Rong | 2023 | Journal of Renewable Materials2023，11，3： | 0 |
| 11 | Heterogeneous assembling 3D free-standing Co@carbon membrane enabling efficient fluid and flexible zinc-air batteries显示文摘Developing an efficient,interface-rich,and free-standing non-noble-metal electrocatalyst is vital for the flexible zinc-air batteries(ZABs).Herein,a three-dimensional(3D)heterogeneous carbon-based flexible membrane was assembled by Co@carbon nanosheets/carbon nanotubes and hollow carbon nanofiber(Co@NS/CNT-CNF)as an efficient oxygen reduction reaction(ORR)catalyst with a positive half-wave potential of 0.846 V and a small Tafel slope of 79 mV·dec^(-1).Meanwhile,the Co@NS/CNT-CNF electrode also exhibits excellent open-circuit voltage,peak power density,and long-time cycling stability in liquid-state ZABs(1.605 V,163 mW·cm^(-2),and 400 h)and flexible ZABs under flat/bending condition(1.47 V,102 mW·cm^(-2),and 80 h).Such heterogeneous flexible membrane architecture not only optimizes the electrolyte infiltration,but also provides capacious possibility for O_(2)and electrolyte transfer.Meanwhile,work-function analyses coupled with density functional theory(DFT)results demonstrate that the electron transfer capability and metal-support interaction can be well optimized in the obtained Co@NS/CNT-CNF catalyst. | Jinming Wang Xiangjian Liu Liuhua Li Rui Liu Yarong Liu Changli Wang Zunhang Lv Wenxiu Yang Xiao Feng Bo Wang | 2023 | Nano Research2023，16，7： | 0 |
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