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| 1 | RS and GIS-based Statistical Analysis of Secondary Geological Disasters after the 2008 Wenchuan Earthquake显示文摘用 RS 和 GIS 工具,这篇文章在 Wenchuan 县,四川省,中华人民共和国以及大规模山崩的特征分析一般地质的特征和结构的带分发特征,泥岩石流动,地震湖,等等,在地震以后在 2008 年 5 月 12 日。基于上述工作,全面室内、室外的研究在有地震,地面,阶层,岩性学,和结构的灾难分发特征和他们的关系上被发射。证据方法的重量被利用到份量上分析并且在地震发生了以后,评估第二等的地质的灾难的空间分发。为第二等的地质的灾难的 3 补救等级从证据的重量的结果被导出,由给补救地震的建议列在后面第二等的灾难。 | CHEN Jianping LI Jianfeng QIN Xuwen DONG Qingji SUN Yan | 2009 | Acta Geologica Sinica(English Edition)2009，83，4： | 13 |
| 2 | Sedimentary records of eutrophication in the Changjiang Estuary upwelling area over last 100 a显示文摘The upwelling area in the Changjiang Estuary was selected to collect the core, where the red tide occurred frequently and hypoxic existed. The total organic carbon (TOC), total nitrogen (TN), biogenic silica (BSi) and stable organic carbon isotopic ratios(δ13 Corg) were determined on the 210Pb-dated sediment core. The concentrations of TOC, TN, BSi as well as their sedimentation fluxes have increased to some extent since the 1970s. TOC and TN fluxes increased about 45%, 36% respectively. The average δ13 Corg value in the core was -23.67×10-3 which remained nearly constant before the 20 century. The δ13 Corg values increased after the 1900s, two marked increases were observed from the 1950s and the 1970s. A simple δ13 Corg model was used to estimate the contribution of terrigenous and marine organic matter inputs for the sediment, which indicated the increase in accumulation since the 1970s has been almost exclusively marine. The increasing of marine organic matter accumulation (TOC, TN and BSi) was corresponding with the increasing of fertilizer consumption and the NO3-N budgets from the Changjiang River. The riverine runoff of fertilizers and nutrients stimulated the algae blooming. Enhanced primary production resulted in an enrichment of organic matter in the sediment. These data support the hypothesis that anthropogenic nutrient loading has been a significant factor on the eutrophication in the Changjiang Estuary. | FENG Xuwen JING Xianglong YU Xiaoguo LI Hongliang CHEN Jianfang QIAN Jiangchu | 2008 | Acta Oceanologica Sinica2008，27，6： | 12 |
| 3 | Zacopride selectively activates the Kir2.1 channel via a PKA signaling pathway in rat cardiomyocytes显示文摘We recently reported that zacopride is a selective inward rectifier potassium current (IK1 ) channel agonist, suppressing ventricular arrhythmias without affecting atrial arrhythmias. The present study aimed to investigate the unique pharmacological properties of zacopride. The whole-cell patch-clamp technique was used to study IK1 currents in rat atrial myocytes and Kir2.x currents in human embryonic kidney (HEK)-293 cells transfected with inward rectifier potassium channel (Kir)2.1, Kir2.2, Kir2.3, or mutated Kir2.1 (at phosphorylation site S425L). Western immunoblots were performed to estimate the relative protein expression levels of Kir2.x in rat atria and ventricles. Results showed that zacopride did not affect the IK1 and transmembrane potential of atrial myocytes. In HEK293 cells, zacopride increased Kir2.1 homomeric channels by 40.7%±9.7% at 50 mV, but did not affect Kir2.2 and Kir2.3 homomeric channels, and Kir2.1-Kir2.2, Kir2.1-Kir2.3 and Kir2.2-Kir2.3 heteromeric channels. Western immunoblots showed that similar levels of Kir2.3 protein were expressed in rat atria and ventricles, but atrial Kir2.1 protein level was only 25% of that measured in the ventricle. In addition, 5-hydroxytryptamine (5-HT) 3 receptor was undetectable, whereas 5-HT 4 receptor was weakly expressed in HEK293 cells. The Kir2.1-activating effect of zacopride in these cells was abolished by inhibition of protein kinase A (PKA), but not PKC or PKG. Furthermore, zacopride did not activate the mutant Kir2.1 channel in HEK293 cells but selectively activated the Kir2.1 homomeric channel via a PKA-dependent pathway, independent to that of the 5-HT receptor. | ZHANG Li LIU QingHua LIU ChengFang ZHAI XuWen FENG QiLong XU RuiLing CUI XiangLi ZHAO ZhiQing CAO JiMin WU BoWei | 2013 | Science China(Life Sciences)2013，56，9： | 7 |
| 4 | Co-regulation of indole glucosinolates and camalexin biosynthesis by CPK5/CPK6 and MPK3/MPK6 signaling pathways^°°显示文摘Secondary plant metabolites,represented by indole glucosinolates(IGS)and camalexin,play important roles in Arabidopsis immunity.Previously,we demonstrated the importance of MPK3 and MPK6,two closely related MAPKs,in regulating Botrytis cinerea(Bc)-induced IGS and camalexin biosynthesis.Here we report that CPK5 and CPK6,two redundant calcium-dependent protein kinases(CPKs),are also involved in regulating the biosynthesis of these secondary metabolites.The loss-of-function of both CPK5 and CPK6 compromises plant resistance to Be.Expression profiling of CPK5-VK transgenic plants,in which a truncated constitutively active CPK5 is driven by a steroidinducible promoter,revealed that biosynthetic genes of both IGS and camalexin pathways are coordinately upregulated after the induction of CPK5-VK,leading to high-level accumulation of camalexin and 4-methoxyindole-3-ylmethylglucosinolate(4MI3G).Induction of camalexin and 4MI3G,as well as the genes in their biosynthesis pathways,is greatly compromised in cpks cpk6 mutant in response to Be.In a conditional cpk5 cpk6 mpk3 mpk6 quadruple mutant,Be resistance and induction of IGS and camalexin are further reduced in comparison to either cpks cpk6 or conditional mpk3 mpk6 double mutant,suggesting that both CPK5/CPK6 and MPK3/MPK6 signaling pathways contribute to promote the biosynthesis of 4MI3G and camalexin in defense against Be. | Liuyi Vang Yan Zhang Rongxia Guan Sen Li Xuwen Xu Shuqun Zhang Juan Xu | 2020 | Journal of Integrative Plant Biology2020，62，11： | 6 |
| 5 | The YDA-MKK4/MKK5-MPK3/MPK6 Cascade Functions Downstream of the RGF1-RGI Ligand-Receptor Pair in Regulating Mitotic Activity in Root Apical Meristem显示文摘The mitotic activity of root apical meristem(RAM)is critical to primary root growth and development.Previous studies have identified the roles of ROOT GROWTH FACTOR 1(RGF1),a peptide ligand,and its receptors,RGF1 INSENSITIVEs(RGIs),a clade of five leucine-rich-repeat receptor-like kinases,in promoting cell division in the RAM,which determines the primary root length.However,the downstream signaling components remain elusive.In this study,we identify a complete mitogen-activated protein kinase(MAPK or MPK)cascade,composed of YDA,MKK4/MKK5,and MPK3/MPK6,that functions downstream of the RGF1-RGI ligand-receptor pair.Similar to the rgi1/2/3/4/5 quintuple mutant,loss-of-function mutants of MPK3 and MPK6,MKK4 and MKK5,or YDA show a short-root phenotype,which is associated with reduced mitotic activity and lower expression of PLETHORA 1(PLT1)/PLT2 in the RAM.Furthermore,MPK3/MPK6 activation in response to exogenous RGF1 treatment is impaired in the rgi1/2/3/4/5 quintuple,yda single,and mkk4 m kk5 double mutants.Epistatic analyses demonstrated that the expression of constitutively active MKK4,MKK5,or YDA driven by the RGI2 promoter can rescue the short-root phenotype of the rgi1/2/3/4/5 mutant.Taken together,these results suggest that the YDA-MKK4/MKK5-MPK3/MPK6 cascade functions downstream of the RGF1-RGI ligand-receptor pair and upstream of PLT1/PLT2 to modulate the stem cell population and primary root growth in Arabidopsis. | Yiming Shao Xinxing Yu Xuwen Xu Yong Li Wenxin Yuan Yan Xu Chuanzao Mao Shuqun Zhang Juan Xu | 2020 | Molecular Plant2020，13，11： | 6 |
| 6 | Memristive Artificial Synapses for Neuromorphic Computing显示文摘Neuromorphic computing simulates the operation of biological brain function for information processing and can potentially solve the bottleneck of the von Neumann architecture.This computing is realized based on memristive hardware neural networks in which synaptic devices that mimic biological synapses of the brain are the primary units.Mimicking synaptic functions with these devices is critical in neuromorphic systems.In the last decade,electrical and optical signals have been incorporated into the synaptic devices and promoted the simulation of various synaptic functions.In this review,these devices are discussed by categorizing them into electrically stimulated,optically stimulated,and photoelectric synergetic synaptic devices based on stimulation of electrical and optical signals.The working mechanisms of the devices are analyzed in detail.This is followed by a discussion of the progress in mimicking synaptic functions.In addition,existing application scenarios of various synaptic devices are outlined.Furthermore,the performances and future development of the synaptic devices that could be significant for building efficient neuromorphic systems are prospected. | Wen Huang Xuwen Xia Chen Zhu Parker Steichen Weidong Quan Weiwei Mao Jianping Yang Liang Chu Xing’ao Li | 2021 | Nano-Micro Letters2021，13，5： | 4 |
| 7 | Marine sponges of the genus Stelletta as promising drug sources: chemical and biological aspects显示文摘Marine sponges of the genus Stelletta are well known as rich sources of diverse and complex biologically relevant natural products, including alkaloids, terpenoids, peptides, lipids, and steroids. Some of these metabolites, with novel structures and promising biological activities, have attracted a lot of attention from chemists seeking to perform their total synthesis in parallel to intensive biological studies towards new drug leads. In this review, we summarized the distribution of the chemically investigated Stelletta sponges, the isolation, synthesis and biological activities of their secondary metabolites, covering the literature from 1982 to early 2018. | Qihao Wu Bastien Nay Min Yang Yeke Ni Hong Wang Ligong Yao Xuwen Li | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 3 |
| 8 | A modified image matching algorithm based on robust Hausdorff distance显示文摘Hausdorff distance measure is one of the widely adopted feature-based image matching algorithms due to its simplicity and accuracy.However,it is considered that its robustness still needs to be improved.In this paper,various forms of original and improved Hausdorff distance(HD) and their limitations are studied.Focusing on robust Hausdorff distance(RHD),an improved RHD with an adaptive outlier point threshold selection method is proposed.Furthermore,another new form of the Hausdorff distance which possesses the merits of RHD and M-HD is prsented.Finally,a recursive algorithm is introduced to accelerate the image matching speed of Hausdorff algorithms.Extensive simulation and experiment results are presented to validate the feasibility of the proposed Hausdorff distance algorithm. | 吴强 Wu Xuefeng Li Xuwen Jia Kebin | 2014 | High Technology Letters2014，20，1： | 3 |
| 9 | Interaction Between Tangeretin and Ovalbumin to Reduce the Allergic Effects of Ovalbumin显示文摘 | SHI Xiaolei ZHANG Ting LI Xuwen FENG Yu TAN Xin JIN Yongri | 2016 | Chemical Research in Chinese Universities2016，32，4： | 2 |
| 10 | Studies on New Steroidal Saponins from Allii macrostemonis Bulbus and Their Antitumor Activities显示文摘 | YAO Hua WANG Tong WU Qian LIU Ying LI Peng LI Xuwen JIN Yongri | 2018 | Chemical Research in Chinese Universities2018，34，1： | 2 |
| 11 | A distributed routing algorithm based-on simplified topology in LEO satellite networks显示文摘 | 曾媛 Liang Xuwen Li Yong | 2010 | High Technology Letters2010，16，2： | 2 |
| 12 | Research Progress of Rice-Fish Integrated Farming显示文摘Rice-fish integrated farming( RFIF) can change the agricultural production pattern from mono-farming model to the co-farming model,and the stereoscopic and integrated farming system established by RFIF can change the flat production to the stereoscopic production. Therefore,RFIF is the important development direction for agriculture to change pattern and adjust structure. In order to further promote development of the research and application of RFIF,the general development situation of RFIF in China was reviewed; the effects of RFIF on increasing farmer' income and enhancing agricultural efficiency were clarified. The technologies matched with RFIF,such as rice paddy engineering technology,safe plant protection technology,security fertilization technology,fish disease prevention and control technology and water quality management technology,were summarized,and the supporting role of RFIF for agriculture was pointed out. In addition,the development prospect of RFIF was proposed,as well as the key research direction of RFIF. | Shunlong MENG Gengdong HU DANDan LI Liping QIU Chao SONG Limin FAN Yao ZHENG Wei WU Jiazhang CHEN Xuwen BING | 2018 | Agricultural Biotechnology2018，7，4： | 2 |
| 13 | Polyoxygenated anti-inflammatory biscembranoids from the soft coral Sarcophyton tortuosum and their stereochemistry显示文摘Five novel biscembranoids,ximaolides H-L(1-5),along with four known related compounds(6-9) were isolated from the Hainan soft coral Sarcophyton tortuosum.The structures of the new compounds were determined by extensive spectroscopic analysis,quantum chemical calculations,and/or by comparing their CD spectra with those of the known compounds.Compounds 1 and 2 are the first examples of biscembranoids bearing a 1,35-bridged lactone moiety,4 is the first biscembranoid comprising an uncommon oxetane ring,and 5 represents the first 36-peroxyl biscembranoid.Ximaolides Ⅰ(2),K(4) and F(9) exhibited interesting anti-inflammatory activity by the inhibition of LPS-induced TNF-α protein release in RAW264.7 macrophages. | Yufen Li Songwei Li Cristina Cuadrado Chenglong Gao Qihao Wu Xiaolu Li Tao Pang Antonio Hernandez Daranas Yuewei Guo Xuwen Li | 2021 | Chinese Chemical Letters2021，32，1： | 1 |
| 14 | Observer-based fuzzy control design with adaptation to delay parameter for time-delay systems 显示文摘 | FU Jiangxie LI Xuwen HAN Qinlong | 2005 | Fuzzy Sets and Systems2005，152，3： | 1 |
| 15 | Studies on Triterpenoid Glycosides from Rhizomes ofPanacis majoris and Their Antiplatelet Aggregation Activity显示文摘A new triterpenoid glycoside(l) and seven known triterpenoid glycosides, pseudoginsenoside RT2(2),yesanchinoside R2(3), vinaginsenoside R13(4), vinaginsenoside R8(5), notoginsenoside E(6), 6"'-O-acetylginsenosideRe(7), 6"-O-acetylginsenoside Rbl(8), were isolated from the rhizomes of Panaeis maforis. The new triterpenoidglycoside was elucidated as 3-O-[β-D-glucopyranosyl-(l→2)-fl-D-(6'-O-ethyl)-glucuronopyranosyl]-oleanolicacid-28-O-β-D-glucopyranoside by extensive spectroscopic and phytochemical methods. Compounds 2-8 wereobtained from the plant for the first time. Compounds 3 and 4 displayed good activities against adenosine diphosphate(ADP)-induced platelet aggregation, and compounds 1, 5, 6 and 8 showed moderate activities. Compound 6 exhibitedmoderate antiplatelet aggregation activity induced by arachidonic acid(AA). | LI Min JIN Yongri WANG Xiaozhong WU Qian LIU Ying LI Peng LI Xuwen | 2016 | Chemical Research in Chinese Universities2016，32，6： | 1 |
| 16 | The exploration of N6-deoxyadenosine methylation in mammalian genomes显示文摘N^(6)-methyladenine(N^(6)-mA,m^(6)dA,or 6mA),a prevalent DNA modification in prokaryotes,has recently been identified in higher eukaryotes,including mammals.Although 6mA has been well-studied in prokaryotes,the function and regulatory mechanism of 6mA in eukaryotes are still poorly understood.Recent studies indicate that 6mA can serve as an epigenetic mark and play critical roles in various biological processes,from transposable-element suppression to environmental stress response.Here,we review the significant advances in methodology for 6mA detection and major progress in understanding the regulation and function of this non-canonical DNA methylation in eukaryotes,predominantly mammals. | Xuwen Li Zijian Zhang Xinlong Luo Jacob Schrier Andrew D.Yang Tao P.Wu | 2021 | Protein & Cell2021，12，10： | 1 |
| 17 | Study on corrosion electrochemical behavior of several different coating systems by EIS 显示文摘 | Liu Xuwen Xiong Jinping Li Yongwu | 2009 | Progress in Organic Coating2009，，64： | 1 |
| 18 | Studies on interaction between flavonoids and bovine serum albumin by spectral methods显示文摘 | SHI Xiaolei LI Xuwen GUI Mingyu | 2010 | Journal of Luminescenc2010，130，4： | 1 |
| 19 | 基于RS/GIS的汶川震后次生地质灾害统计分析显示文摘采用遥感(RS)与地理信息系统(GIS)相结合的手段和方法,分析了汶川地区区域地质概况、主要构造带的分布性状,以及2008年5月12日地震后大型滑坡、泥石流、堰塞湖等地质灾害的发育特征。在上述工作完成的基础上,进一步开展室内外综合研究,从遥感宏观分析角度通过对地质灾害分布特征以及与地震、地貌、地层、岩性、构造等相互关系的综合分析,利用证据权重法对区域地质灾害发生发展的空间性做出定量的综合评价,并依此提出对研究区的灾害治理进行分级,随后给出治理的建议。 | CHEN Jianping LI Jianfeng QIN Xuwen DONG Qingji 孙岩(译) 李剑峰(译) | 2012 | 世界地震译丛2012，，1： | 1 |
| 20 | Phenotypic plasticity and genetic variation of cotton yield and its related traits under water-limited conditions显示文摘Global warming is limiting availability of water resources in arid and semi-arid regions,and so understanding water use efficiency(WUE)is increasingly important for agricultural production in those areas.As China is the largest cotton producing area,the problem of balancing WUE and efficient cotton production is a major issue.In this study,we used a natural population of 517 Upland cotton accessions to conduct a water-controlled trial in south and north of Xinjiang over two years.A total of 18 traits including agronomic traits,fiber yield indices and fiber quality indices,were investigated for broad-sense heritability and coefficient of variation.Appropriate water limitation was found to promote the establishment of favorable agronomic traits in cotton,associated with an increased cotton yield of 8.46%in Xinjiang,at the expense of a certain degree of fiber quality,such as decreased fiber length and an over-higher micronaire value.We detected 33 QTL related to response to water limitation using a drought resistance coefficient(DRC),and 6 QTL were found using a comprehensive indicator of CIDT(comprehensive index of drought tolerance)at the genetic level by integrating resequencing data.Two novel QTL-hotspots including six differentially expressed genes(DEGs)were further identified related to the drought response of cotton.These findings not only suggested a new approach to irrigation of cotton fields in Xinjiang,but also provided abundant genetic evidence for genetic breeders to study drought improvement of crops. | Baoqi Li Qin Tian Xuwen Wang Bei Han Li Liu Xianhui Kong Aijun Si Juan Wang Zhongxu Lin Xianlong Zhang Yu Yu Xiyan Yang | 2020 | The Crop Journal2020，8，6： | 1 |
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