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| 1 | Research progress on electrical signals in higher plants显示文摘This review introduces the characteristics of electrical signals in higher plants and their corresponding physiological significance, and describes in detail the impact of environmental factors (e.g. light and temperature) on the electrical potential of the plants. Also, we evaluate the measurement techniques used for electrical signals in plants, including intracellular measurement, extracellular measurement, measurement of the ion channel based on the patch-clamp technique and on the non-invasive microelectrode vibrating probe technique. We also give a brief review of the applications of these methods for investigating electrical signals in plants. The ionic mechanism of electrical activity in plants is then discussed in terms of environmental response in higher plants, and this is used to provide a theoretical basis for quantitative description of the electrical signals in plants. A model for interpretation of the electrical signal mechanisms in higher plants is discussed, but further experiments are required for the verification of this model. | Xiaofei Yana, Zhongyi Wang a, Lan Huang a, Cheng Wang b, Ruifeng Hou b, Zhilong Xu b, Xiaojun Qiao b a College of Information and Electrical Engineering, China Agricultural University, Beijing 100083, China b National Engineering Research Center for Information Technology in Agriculture, Beijing 100097, China | 2009 | Progress in Natural Science:Materials International2009，19，5： | 13 |
| 2 | miR-21 promotes the differentiation of hair folliclederived neural crest stem cells into Schwann cells显示文摘Hair follicle-derived neural crest stem cells can be induced to differentiate into Schwann cells in vivo and in vitro. However, the underlying regulatory mechanism during cell differentiation remains poorly understood. This study isolated neural crest stem cells from human hair follicles and induced them to differentiate into Schwann cells. Quantitative RT-PCR showed that microRNA(miR)-21 expression was gradually increased during the differentiation of neural crest stem cells into Schwann cells. After transfection with the miR-21 agonist(agomir-21), the differentiation capacity of neural crest stem cells was enhanced. By contrast, after transfection with the miR-21 antagonist(antagomir-21), the differentiation capacity was attenuated. Further study results showed that SOX-2 was an effective target of miR-21. Without compromising SOX2 mRNA expression, miR-21 can down-regulate SOX protein expression by binding to the 3′-UTR of miR-21 mRNA. Knocking out the SOX2 gene from the neural crest stem cells significantly reversed the antagomir-21 inhibition of neural crest stem cells differentiating into Schwann cells. The results suggest that miR-21 expression was increased during the differentiation of neural crest stem cells into Schwann cells and miR-21 promoted the differentiation through down-regulating SOX protein expression by binding to the 3′-UTR of SOX2 mRNA. | Yuxin Ni Kaizhi Zhang Xuejuan Liu Tingting Yang Baixiang Wang Li Fu Lan A Yanmin Zhou | 2014 | Neural Regeneration Research2014，9，8： | 9 |
| 3 | Prognostic implication of isolated tumor cells and micrometastases in regional lymph nodes of gastric cancer显示文摘AIM: To determine the prognostic significance of isolated tumor cells (ITCs) and lymph node micrometastases in gastric cancer.METHODS: Hematoxylin and eosin-stained slides of lymph node dissections of 632 consecutive gastric cancers were reviewed. Cytokeratin immunostaining was performed in 280 node-negative cases and 5 cases indefinite for lymph node metastases. Lymph node metastases were divided into ITC s, micrometastases, or macrometastases, according to the sizes of tumor deposits in largest dimension. ITCs were further classified into four groups according to metastasis pattern.RESULTS: Lymph node metastases were identified by immunostaining in 58 of 280 node-negative cases (20.7%)and were not significantly associated with patient survival (P = 0.3460). After cytokeratin immunostaining, 196 cases were classified as pN1, which consisted of 20 cases with micrometastases detected by immunostaining (pN1mi(i+)),34 cases with only micrometastases (pN1mi), and 142 cases with pN1 with one or more macrometastases (pN1).Cases with pN1mi and pN1mi(i+) had a significantly better prognosis than the cases with pN1 (P = 0.0037). ITCs were found in 38 of these 58 cases, and could be divided into four groups: 12 cases with only a single cell pattern,7 cases with multiple individual cells, 5 cases with single small cluster, and 14 cases with multiple small clusters.Among these four groups, cases with ITCs of multiple individual cell pattern showed the worst survival (median survival: 28 mo, P<0.0001).CONCLUSION: Both size and pattern of lymph node metastases can give prognostic information on the survival of gastric cancer patients. | Hye Seung Lee Min A Kim Han-Kwang Yang Byung Lan Lee Woo Ho Kim | 2005 | World Journal of Gastroenterology2005，11，38： | 5 |
| 4 | Noncoherent sequential acquisition of PN sequence for DS/SS communications with/without dhannel fading显示文摘 | TANTARTANS S LAN A W VINCENT P J | 1995 | IEEE Trans on COM1995，43，2： | 2 |
| 5 | Caveolin 1 Expression Correlates with Poor Prognosis and Focal Adhesion Kinase Expression in Gastric Cancer显示文摘 | Nam Kyung Han Lee Byung Lan Park Joo Hyun Kim Jin Han Nayoung Lee Hee Eun Kim Min A Lee Hye Seung Kim Woo Ho | 2012 | Pathobiology2012，，2： | 2 |
| 6 | Environmental tax reform and endogenous growth显示文摘 | A Lans Bovenberg Ruud A de Mooij | 1997 | Journal of Public Economics1997，，2： | 2 |
| 7 | Experimental colonic phantom for the evaluatlon of the optimal scanning technique for CT colonography using a multidetector spiral CT equipntent显示文摘 | Laghi A lan naccone R Man giapane F | 2003 | Eur Radiol2003，13，3： | 1 |
| 8 | Endothelin-1 modulates hemoglobin-me-diated signaling in cerebrovascular smooth muscle via RhoA/Rho kinase and protein kinase C显示文摘 | Lan C Das D Wloskowicz A | 2004 | Am J Physiol Heart Circ Physiol2004，286，： | 1 |
| 9 | An EST-enriched comparative map of Brassica oleracea and Arabidopsis thaliana 显示文摘 | Lan T H DelMonte T A Reischmann K P | 2000 | Genome Research2000，10，： | 1 |
| 10 | Aflp phylogeny of mimulus section erythranthe and the evolution of hummingbird pollination 显示文摘 | Beardsley P Aul Yen A Lan Olmstead R Iehard | 2003 | Evolution2003，57，6： | 1 |
| 11 | Mechanisms involved in the regulation ofhistone lysine demethylases显示文摘 | Lan F Nottke A C Shi Y | 2008 | Curr Opin Cell Biol2008，20，3： | 1 |
| 12 | Reeonstitution of a functional human immune system in immunodefieient mice through combined human fetal thymus/liver and CD34^+ cell transplantation显示文摘 | Lan P Tonomura N Shimizu A | 2006 | Blood2006，208，2： | 1 |
| 13 | Thiopental- induced neutropenia in two patients with severe head trauma显示文摘 | Frenette A Perreault MM Lan S | 2007 | Pharmacotherapy2007，27，3： | 1 |
| 14 | Endothelin-1 modulates hemoglobin-mediated signaling in cerebrovascular smooth muscle via RhoA/Rho kinase and protein kinase C显示文摘 | Lan C Das D Wloskowicz A | 2004 | Am J Physiol Heart Circ Physiol2004，286，1： | 1 |
| 15 | Determination of the elastic and plastic properties of materials through instrumented indentation with reduced sensitivity显示文摘 | LAN H Z VENKATESH T A | 2007 | Acta Materialia2007，55，： | 1 |
| 16 | The Capture and Destruction of Escherichia coli from Simulated Urban Runoff Using Conventional Bioretention Media and Iron Oxide-coated Sand显示文摘 | Zhang Lan Seagren Eric A Davis Allen P Karns Jeffrey S | 2010 | Water Environment Research2010，，8： | 1 |
| 17 | Properties and synthetic utili tyof N substituted benzotriazoles显示文摘 | Katritzky A R Lan X F Yang J Z | 1998 | Chem Rev1998，98，2： | 1 |
| 18 | mGluRl-media- ted potentiation of NMDA receptors involves a rise in in- traceUular calcium and activation of protein kinase C 显示文摘 | Skeberdis V A Lan J Opitz T | 2001 | Neuropharmacology2001，40，： | 1 |
| 19 | Stability of ca- nine distemper virus (CDV) after 20 passages in Vero DST cells expressing the receptor protein for CDV 显示文摘 | Lan N T Yamaguchi R Kawabata A | 2006 | Veterinary Microbiology2006，118，17： | 1 |
| 20 | Q-VD-OPh,a pancaspase inhibitor,reduces trauma-induced apoptosis and improves the recovery of hind-limb function in rats after spinal cord injury显示文摘 | Colak A Antar V Karao?lan A | | 0，，： | 1 |
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