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| 1 | Variations between rice cultivars in iron and manganese plaque on roots and the relation with plant cadmium uptake显示文摘To understand certain mechanisms causing variations between rice cultivars with regard to cadmium uptake and tolerance,pot soil experiments were conducted with two rice cultivars of different genotypes under different soil Cd levels.The relationships between plant Cd uptake and iron/manganese(Fe/Mn) plaque formation on roots were investigated.The results showed that rice cultivars di?ered markedly in Cd uptake and tolerance.Under soil Cd treatments,Cd concentrations and accumulations in the cultivar Shanyou 63(the genotype indica) were significantly higher than those in the cultivar Wuyunjing 7(the genotype japonica)(P < 0.01,or P < 0.05),and Shanyou 63 was more sensitive to Cd toxicity than Wuyunjing 7.The differences between the rice cultivars were the largest at relatively low soil Cd level(i.e.,10 mg/kg).Fe concentrations in dithionite-citrate-bicarbonate root extracts of Shanyou 63 were generally lower than that of Wuyunjing 7,and the difference was the most significant under the treatment of 10 mg Cd/kg soil.The results indicated that the formation of iron plaque on rice roots could act as a barrier to soil Cd toxicity,and may be a 'buffer' or a 'reservoir' which could reduce Cd uptake into rice roots.And the plaque may contribute,to some extent,to the genotypic differences of rice cultivars in Cd uptake and tolerance. | Jianguo Liu Changxun Cao Minghung Wong Zhijun Zhang Yuhong Chai | 2010 | Journal of Environmental Sciences2010，22，7： | 43 |
| 2 | Vision,Requirements and Network Architecture of 6G Mobile Network beyond 2030显示文摘With the 5th Generation(5G)Mobile network being rolled out gradually in 2019,the research for the next generation mobile network has been started and targeted for 2030.To pave the way for the development of the 6th Generation(6G)mobile network,the vision and requirements should be identified first for the potential key technology identification and comprehensive system design.This article first identifies the vision of the society development towards 2030 and the new application scenarios for mobile communication,and then the key performance requirements are derived from the service and application perspective.Taken into account the convergence of information technology,communication technology and big data technology,a logical mobile network architecture is proposed to resolve the lessons from 5G network design.To compromise among the cost,capability and flexibility of the network,the features of the 6G mobile network are proposed based on the latest progress and applications of the relevant fields,namely,on-demand fulfillment,lite network,soft network,native AI and native security.Ultimately,the intent of this article is to serve as a basis for stimulating more promising research on 6G. | Guangyi Liu Yuhong Huang Na Li Jing Dong Jing Jin Qixing Wang Nan Li | 2020 | China Communications2020，17，9： | 37 |
| 3 | Optimization approach of background value and initial item for improving prediction precision of GM(1,1) model显示文摘A combination method of optimization of the background value and optimization of the initial item is proposed. The sequences of the unbiased exponential distribution are simulated and predicted through the optimization of the background value in grey differential equations. The principle of the new information priority in the grey system theory and the rationality of the initial item in the original GM(1,1) model are fully expressed through the improvement of the initial item in the proposed time response function. A numerical example is employed to illustrate that the proposed method is able to simulate and predict sequences of raw data with the unbiased exponential distribution and has better simulation performance and prediction precision than the original GM(1,1) model relatively. | Yuhong Wang Qin Liu Jianrong Tang Wenbin Cao Xiaozhong Li | 2014 | Journal of Systems Engineering and Electronics2014，25，1： | 32 |
| 4 | Proteomics Associated with Virulence Differentiation of Curvularia lunata in Maize in China显示文摘蛋白质的一个维的电气泳动(1-DE ) ,蛋白质的 two-dimensionalelectrophoresis (2-DE ) 并且 cDNA 顺序克隆被用来学习 Curvularia lunata 的毒力区别[Cochliobolus lunatus ] 在中国从玉米(Zea maydis ) 孤立。从蛋白质的 1-DE 胶化侧面, 110 个可再现的乐队与六被分开 C 孤立。lunata CX-3, SD-6, C-152, C107-1, DD-60 和 W-18。68 个乐队(61.82%) 是多态的,建议在 isolates 之中的巨大的生物多样性。所有孤立组由 0.605 的系数价值由不同剧毒的类型组成因为实验被聚类进三。组织 1,由有高毒力的 CX-3, SD-6 和 C-152 组成比组显示了更多的蛋白质乐队第 2a 3,与低毒力由 C107-1 和 DD-60 组成。Proteomics 途径基于 2-DEtechniques 被使用识别在 CX-3 和 DD-60 与毒力区别联系的特定的蛋白质。423 个蛋白质点的一个总数被分开。从他们, 75 个特定的蛋白质点在 2-DE 胶化被显示。在他们之中, 28 个蛋白质点在 CX-3 是唯一的, 8 在两 2-DE 胶化上在 DD-60,和 39 个蛋白质点被显示出,但是在紧张不同地表示。包括三个唯一的蛋白质点和 17 差别的 Twentyprotein 点在 CX-3 表示了蛋白质点(超过 2 褶层 DD-60 ) 进一步与 MALDI-TOF MS/MS 被识别。结果显示大多数识别蛋白质被发现与毒力区别,新陈代谢,压力反应和信号转导被联系。他们之一作为 Brn1 蛋白质被识别,它被报导了在真菌与黑素生合成和毒力区别有关。与我们的以前的调查结果结合了,我们假设那 Brn1 蛋白质和它的调整产品可能涉及 C 的毒力区别。lunata。因而,我们克隆 Brn1cDNA 碎片并且在另外的真菌与碎片联盟。结果显示 Brn1 的 633-bpsequence 在 C 克隆。lunata 是高度与比较真菌逻辑的人。为在我们的情况中的 Brn1 的准确基因角色的进一步的工作是在进行之中的…… | Shufa Xu Jie Chen Lixing Liu Xiaofei Wang Xiuli Huang Yuhong Zhai | 2007 | Journal of Integrative Plant Biology2007，49，4： | 25 |
| 5 | A comparative study between graphene oxide and diamond nanoparticles as water-based lubricating additives显示文摘The tribological properties of graphene oxide(GO) nanosheets and modified diamond(MD) nanoparticles with excellent water-solubility were investigated.GO nanosheets were synthesized using carbon fibers with a regular and uniform size,the lateral size being around 30 nm and the thickness being 2 or 3 nm,while MD nanoparticles were about 30 nm in the three dimensions.The friction properties of ceramics were improved by GO nanosheets or MD nanoparticles used as additives in water-based lubrication,though the effects of two nanoparticles were quite different.For GO nanosheets,the friction coefficient at the beginning decreased sharply from 0.6 to 0.1,as compared with the dionized water lubrication.At the same time,the running-in period was shortened from 2000 s to 250 s.A steady state characterized by ultralow friction(friction coefficient=0.01) was obtained after the running-in period.In the case of MD nanoparticles,the friction coefficient stayed at 0.1 without further decrease during the whole experiment.Based on the observation of wear scar and characterization of remains on the wear track,the positive effect of GO nanosheets was attributed to their lamellar structure and geometric size.MD nanoparticles reduced friction by forming the regularly grained surface on the mating surfaces,and prevented further reduction in steady-state friction coefficient owing to their larger size and hardness.In conclusion,GO nanosheets exhibited favorable potential as an effective additive for water-based lubrication. | LIU YuHong WANG XiaoKang PAN GuoShun LUO JianBin | 2013 | Science China(Technological Sciences)2013，56，1： | 21 |
| 6 | Compound Zhebei granules combined with chemotherapy for the treatment of refractory acute leukemia: a randomized clinical trial显示文摘OBJECTIVE: To observe the effect of compound Zhebei granules(CZBG) with chemotherapy in the treatment of refractory acute leukemia.METHODS: In this multicenter, double-blind, placebo-controlled clinical trial, we used a central(online) randomization system to assign 235 patients to two treatment groups. A total of 118 patients received chemotherapy combined with CZBG(4 g,twice daily) and 117 patients received chemotherapy plus placebo. The clinical efficacy was evaluated at the end of one chemotherapeutic cycle.RESULTS: In the full analysis set, in which deaths due to disease progression were regarded as inefficacy, the rates of complete remission(CR) and partial remission(CR + PR) were 32.35% and 50.00%,respectively, for the chemotherapy combined with CZBG group, and 23.08% and 35.58%, respectively,for the chemotherapy plus placebo group. There was a statistically significant difference between the two groups according to a ysis set(PPχ2test(P < 0.05). In the per protocol analS), the CR(33.67%),CR+PR(52.04%) response rates for the chemotherapy plus CZBG group were significantly different from the response rates of the control group(CR:24.24% and CR+PR: 37.37%), respectively(P < 0.05).CONCLUSION: CZBG plus chemotherapy can improve the clinical remission rate of refractory acute leukemia after one just one therapeutic cycle. | Hou Li Yang Shulian Yang Wenhua Zhou Yuhong Liu Feng Yang Hongyong Sun Weizheng Li Dongyun Xu Yamei Chen Xinyi | 2016 | Journal of Traditional Chinese Medicine2016，36，5： | 13 |
| 7 | Characterization and evaluation of rice blast resistance of Chinese indica hybrid rice parental lines显示文摘The development of resistant varieties and hybrid combinations has been the most effective and economical strategy to control blast disease caused by Magnaporthe oryzae.However, the distribution of major R genes and blast resistance characterization in hybrid rice parents has not been well investigated, resulting in their limited use in hybrid rice blast-resistance breeding. In the present study, 88 elite indica hybrid rice parental lines were evaluated with 30 isolates of M. oryzae collected from the main planting area of indica hybrid rice in China and were characterized for the presence of 11 major resistance genes using molecular markers. The pathogenicity assays showed that four types of hybrid rice parent line showed some resistance to M. oryzae. However, the proportions of highly resistant lines and the mean resistance frequency(RF) varied among the four types, with resistance in decreasing order shown by three-line restorer lines, three-line maintainer lines, two-line sterile lines, and two-line restorer lines. All 88 hybrid rice parental lines carried more than one R gene, but none carried the R genes Pi1 and Pi2. Although Pid3 and Pi9 were present only in three-line restorer lines and Pigm only in three-line maintainer lines, the remaining six R genes(Pib, Pid2, Pi5, Pia, Pi54, and Pita) were present in the four types of hybrid rice parent with significantly different distribution frequencies. The correlation between R genes and resistance reactions was investigated. The results are expected to provide useful information for rational utilization of major R genes in hybrid rice breeding programs. | Yunyu Wu Ling Yu Ning Xiao Zhengyuan Dai Yuhong Li Cunhong Pan Xiaoxiang Zhang Guangqing Liu Aihong Li | 2017 | The Crop Journal2017，5，6： | 10 |
| 8 | Molecular behaviors in thin film lubrication——Part one: Film formation for different polarities of molecules显示文摘There are three unsolved problems in thin film lubrication(TFL) since it was proposed 20 years ago, i.e., the determination of the type of molecules that can enter the contact region efficiently during sliding, the orientation of molecules in the contact region, and the effect of solid surfaces on the liquid molecular orientation in TFL. In order to answer the first two questions, an in situ measurement system comprising a self-designed Raman microscopy and relative optical interference intensity(ROⅡ) system was set up to study the molecular behaviors. A variety of binary mixtures were used as lubricants in the test, and the concentration distribution profile and orientation of the additive molecules in TFL were characterized. The molecular behavior was determined via a combination of shearing, confinement, and surface adsorption. Furthermore, the difference in molecular polarity resulted in different competing effect of surface adsorption and intermolecular interaction, the influence of which on molecular behavior was discussed. Polar additive molecules interacted with the steel surface and exhibited an enrichment effect in the Hertz contact region when added into a nonpolar base oil. No enrichment effect was observed for nonpolar molecules that were added into the nonpolar base oil and polar molecules added into polar base oil. The enrichment of additive molecules enhanced the film-forming ability of the lubricant and resulted in a reduction in the friction coefficient of up to 61%. The orderly arrangement of the additive molecules was another reason for the friction-reducing. A binary multilayer model was proposed to illuminate the molecular behavior in the TFL, and the model was supported by contrary experiment results in elastohydrodynamic lubrication. This research may aid in understanding the nanoscale lubrication mechanism in TFL and the development of novel liquid lubricants. | Shaohua ZHANG Yijun QIAO Yuhong LIU Liran MA Jianbin LUO | 2019 | Friction2019，7，4： | 10 |
| 9 | Modification on the tribological properties of ceramics lubricated by water using fullerenol as a lubricating additive显示文摘It is necessary to modify the running-in process for the application of ceramics using water as a lubricant in real conditions because ceramics sliding in water are characterized by a running-in period with severe friction and wear.Fullerenol,a kind of highly water-soluble nanoparticle,was synthesized and then used to ameliorate the tribological properties of Si 3 N 4 sliding against Al 2 O 3 in pure water.With the addition of fullerenol,the running-in period was shortened from 30 min to 100 s at a speed of 250 mm/s.The speed threshold above which ultralow friction can be obtained in a short time was expanded from 450 mm/s to 80 mm/s.Meanwhile,the load-carrying ability of water film was increased.The role of fullerenol was discussed based on observation of the wear scar by an optical interferometer and XPS characterization of the tribo-film on the wear track. | LIU YuHong WANG XiaoKang LIU PengXiao ZHENG JunPeng SHU ChunYing PAN GuoShun LUO JianBin | 2012 | Science China(Technological Sciences)2012，55，9： | 9 |
| 10 | Preparation of poly (N-isopropylacrylamide) brush bonded on silicon substrate and its water-based lubricating property显示文摘The poly (N-isopropylacrylamide) brush was covalently bonded on an initiator-coated silicon wafer via surface-initiated atom transfer radical polymerization. The polymer brush was (76.2±0.1) nm in thickness (by ellipsometer) with a grafting density of ca. 0.27 chains/nm 2 . The tribological properties of the poly (N-isopropylacrylamide) brush were investigated by means of ball-on-disk tests in a rotational mode under water lubrication for tribological application. The experimental results exhibited a low friction coefficient of ca. 0.03. The excellent lubrication property of the brush was due to its amide groups in the polymer chains. It was supposed that the good lubrication property of the brush was attributed to the cross-linked polymer network formed by the hydrogen bond association of N-H…O==C and the water molecular layer adsorbed by the terminal amide groups in the brush. The poly (N-isopropylacrylamide) solution also exhibits a lubrication property due to physical adsorption of the polymer chains. | LIU YuHong XIAO YuQi LUO JianBin | 2012 | Science China(Technological Sciences)2012，55，12： | 9 |
| 11 | Tribological Properties of Few-layer Graphene Oxide Sheets as Oil-Based Lubricant Additives显示文摘The performance of a lubricant largely depends on the additives it involves. However, currently used additives cause severe pollution if they are burned and exhausted. Therefore, it is necessary to develop a new generation of green additives. Graphene oxide(GO) consists of only C, H and O and thus is considered to be environmentally friendly. So the tribological properties of the few-layer GO sheet as an additive in hydrocarbon base oil are investigated systematically. It is found that, with the addition of GO sheets, both the coefficient of friction(COF) and wear are decreased and the working temperature range of the lubricant is expanded in the positive direction. Moreover, GO sheets has better performance under higher sliding speed and the optimized concentration of GO sheets is determined to be 0.5wt%. After rubbing, GO is detected on the wear scars through Raman spectroscopy. And it is believed that, during the rubbing, GO sheets adhere to the sliding surfaces, behaving like protective films and preventing the sliding surfaces from contacting with each other directly. This paper proves that the GO sheet is an effective lubricant additive, illuminates the lubrication mechanism, and provides some critical parameters for the practical application of GO sheets in lubrication. | CHEN Zhe LIU Yuhong LUO Jianbin | 2016 | Chinese Journal of Mechanical Engineering2016，29，2： | 9 |
| 12 | Comparison analysis between haplo identical stem cell transplantation and matched sibling donor stem cell transplantation for high-risk acute myeloid leukemia in first complete remission显示文摘In order to compare the effect between haploidentical(HID) stem cell transplantation(HSCT) and matched sibling donor(MSD)stem cell transplantation for high-risk acute myeloid leukemia(AML) in first complete remission status(CR1), we retrospectively studied 170 cases who received stem cell transplantation from Jan 2008 to Jul 2015 in Peking University People's Hospital. We divided all cases into MSD group(43 cases) and HID(127 cases) group. Patients in HID and MSD group displayed similar baseline characteristics except for age distribution. There were no statistic differences for overall survival(OS), cumulative incidence of relapse, leukemia free survival(LFS), transplantation related mortality(TRM) between HID and MSD group. The 3-year OS, LFS for all patients was 63.9% and 59.7% respectively. Multivariate analysis showed that grade III-IV acute graft versus host disease(aGVHD) was an independent risk factor for treatment related mortality(HR=8.134, 95% CI:3.210–20.611, P<0.001), monosomy/complex chromosomal karyotype and white blood cell count more than 50×109 L-1 were two independent factors for relapse(HR=1.533, 95% CI: 1.040–2.260, P=0.031)(HR=1.004, 95% CI: 1.001–1.008, P=0.015).Grade III-IV aGVHD was an independent factor for mortality(HR=3.184, 95% CI: 1.718–5.902, P<0.001). These results demonstrated some risk factors for high-risk AML leukemia transplantation and indicated for AML patients in CR1 status, haplo stem cell transplantation could have the same therapeutic effect as MSD transplantation. | Yang Liu Xiaojun Huang Qian Fei Lanping Xu Xiaohui Zhang Kaiyan Liu Yuhong Chen Huan Chen Yu Wang | 2019 | Science China(Life Sciences)2019，62，5： | 9 |
| 13 | Self-Assembled Silane Film and Silver Nanoparticles Coating on Magnesium Alloys for Corrosion Resistance and Antibacterial Applications显示文摘Contamination resulting from microbial adhesion on magnesium alloys is very common in many applications.Self-assembly technology was employed to prepare an antibacterial composite coating by fixing silver nanoparticles(AgNPs)onto the surface of magnesium alloys.The AgNPs were immobilized on the surface of3-aminopropyltrimethoxysilane(APTMS)-modified magnesium alloy AZ31(APTMS/Mg)through electrostatic inter-attraction between partially protonated amino groups and negatively charged citrate-capped AgNPs,resulting in the AgNPs attached APTMS/Mg(AgNPs/APTMS/Mg)substrate.The prepared Ag colloid and functionalized AZ31 alloy were characterized by ultraviolet-visible(UV-vis)spectroscopy,Fourier transform infrared(FTIR)spectroscopy,scanning electron microscopy(SEM),and electrochemical methods.Finally,the bactericidal activity of AgNPs/APTMS/Mg substrate against Escherichia coli was assessed by the inhibition zone.The results demonstrated that Si-O-Si covalent bonds existed on the substrate with the formation of inorganic Si-O-Mg bonds.AgNPs were immobilized and well-dispersed,forming a uniform submonolayer on the silane film in two dimensions.The AgNPs/APTMS-pretreated AZ31 alloys exhibited better corrosion resistance and excellent antibacterial performance. | Rongchang ZENG Lijun LIU Shuoqi LI Yuhong ZOU Fen ZHANG Yanan YANG Hongzhi CUI En-hou HAN | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，6： | 8 |
| 14 | The SOLIDS 6G Mobile Network Architecture:Driving Forces,Features,and Functional Topology显示文摘With the large-scale commercial launch of fifth generation(5G)mobile network,the development of new services and applications catering to the year 2030,along with the deep convergence of information,communication,and data technologies(ICDT),and the lessons and experiences from 5G practice will drive the evolution of the next generation of mobile networks.This article surveys the history and driving forces of the evolution of the mobile network architecture and proposes a logical function architecture for sixth generation(6G)mobile network.The proposed 6G network architecture is termed SOLIDS(related to the following basic features:soft,on-demand fulfillment,lite,native intelligence,digital twin,and native security),which can support self-generation,self-healing,self-evolution,and self-immunity without human involvement and address the primary issues in the legacy 5G network(e.g.,high cost,high power consumption,and highly complicated operation and maintenance),significantly well. | Guangyi Liu Na Li Juan Deng Yingying Wang Junshuai Sun Yuhong Huang | 2022 | Engineering2022，8，1： | 8 |
| 15 | U-Pb Zircon Age, Geochemical, and Sr-Nd-Pb Isotopic Constraints on the Age and Origin of Mafic Dykes from Eastern Shandong Province, Eastern China显示文摘U-Pb 锆石年龄, geochemical,和从东方山东省的 mafic 女同性恋的 Sr-Nd-Pb 同位素的数据,东方中国此处被报导。激光脱离诱导地联合了从调查 mafic 女同性恋的二件样品的 U-Pb 锆石分析产出一致年龄从 121.9 妈的血浆团 spectrometry (LA-ICP-MS )?????? 猠潨桳湯瑩捩吗? | LIU Shen HU Ruizhong FENG Caixia GAO Shan FENG Guangying LAI Shaocong QI Youqiang Ian M. COULSON YANG Yuhong YANG Chaogui TANG Liang | 2013 | Acta Geologica Sinica(English Edition)2013，87，4： | 7 |
| 16 | Improved clinical outcomes of rhG-CSF-mobilized blood and marrow haploidentical transplantation compared to propensity score-matched rhG-CSF-primed peripheral blood stem cell haploidentical transplantation:a multicenter study显示文摘The effects of haploidentical rhG-CSF-mobilized blood and marrow transplantation(HBMT) on hematological malignances are well established. Previous prospective single-center studies have demonstrated better survival after HBMT versus haploidentical rhG-CSF-mobilized peripheral blood stem cell transplantation(HPBSCT) for acute leukemia(AL) not in remission(NR) or in more than the second complete remission(>CR2). To test the hypothesis that HBMT is still superior to HPBSCT for patients with AL, multiple myeloma(MM), or non-Hodgkin lymphoma(NHL) in CR1/CR2 and for patients with chronic myeloid leukemia in the first and second chronic phase lacking a matched donor, we designed a propensity score method-based multicenter study.Hematopoietic recovery, acute graft-versus-host disease(aGVHD), and chronic GVHD were comparable between the HBMT group(n=168) and the HPBSCT group(n=42). No significant differences were found in non-relapse mortality rate(20.17%±3.58%and 27.24%±7.16%, P=0.18) or relapse rate(19.96%±3.72% and 28.49%±8.25%, P=0.32) between the HBMT group and the HPBSCT group. HBMT recipients had better overall survival(65.0%±4.2% and 54.2%±8.3%, P=0.037) and disease-free survival(59.9%±4.6% and 44.3%±8.7%, P=0.051). Multivariate analysis showed that HPBSCT was associated with poorer DFS(HR(95%CI), 1.639(0.995–2.699), P=0.052). Our comparisons showed that HBMT was superior to HPBSCT as a post-remission treatment for patients lacking an identical donor. | Xiangyu Zhao Feng Gao Xiaohui Zhang Yu Wang Lanping Xu Kaiyan Liu Xiaosu Zhao Yingjun Chang Han Wei Huan Chen Yuhong Chen Zhengfan Jiang Xiaojun Huang | 2016 | Science China(Life Sciences)2016，59，11： | 7 |
| 17 | Donor-Derived CD19-Targeted T Cell Infusion Eliminates B Cell Acute Lymphoblastic Leukemia Minimal Residual Disease with No Response to Donor Lymphocytes after Allogeneic Hematopoietic Stem Cell Transplantation显示文摘Leukemia relapse is still the leading cause of treatment failure after allogeneic hematopoietic stem cell transplantation (allo-HSCT) for B cell acute lymphoblastic leukemia (B-ALL). Relapsed patients with BALL after allo-HSCT have a very short median survival. Minimal residual disease (MRD) is predictive of forthcoming hematological relapse after hematopoietic stem cell transplantation (HSCT);furthermore, eliminating MRD effectively prevents relapse. Donor lymphoblastic infusion (DLI) is the main established approach to treat B-ALL with MRD after allo-HSCT. However, about one-third of patients with MRD are non-responsive to DLI and their prognosis worsens. Although donor-derived cluster of differentiation (CD)19-directed chimeric antigen receptor-modified (CAR) T cells (CART19s) can potentially cure leukemia, the efficiency and safety of infusions with these cells have not yet been investigated in patients with MRD after HSCT. Between September 2014 and February 2018, six patients each received one or more infusions of CART19s from HSCT donors. Five (83.33%) achieved MRD-negative remission, and one case was not responsive to the administration of CAR T cells. Three of the six patients are currently alive without leukemia. No patient developed acute graft-versus-host disease (aGVHD), and no patient died of cytokine release syndrome. Donor-derived CAR T cell infusions seem to be an effective and safe intervention for patients with MRD in B-ALL after allo-HSCT and for those who were not responsive to DLI. | Yifei Cheng Yuhong Chen Chenhua Yan Yu Wang Xiangyu Zhao Yao Chen Wei Han Lanping Xu Xiaohui Zhang Kaiyan Liu Shasha Wang Lungji Chang Lei Xiao Xiaojun Huang | 2019 | Engineering2019，5，1： | 7 |
| 18 | Genome-wide identification of OSCA gene family and their potential function in the regulation of dehydration and salt stress in Gossypium hirsutum显示文摘Background:Cotton(Gossypium hirsutum) provides the largest natural fiber for the textile manufacturing industries,but its production is on the decline due to the effects of salinity.Soil salt-alkalization leads to damage in cotton growth and a decrease in yields.Hyperosmolality-gated calcium-permeable channels(OSCA) have been found to be involved in the detection of extracellular changes which trigger an increase in cytosolic free calcium concentration.Hyperosmolality-induced calcium ion increases have been widely speculated to be playing a role in osmosensing in plants.However,the molecular nature of the corresponding calcium ion channels remains unclearly.In this research work,we describe the OSCA genes and their putative function in osmosensing in plants by carrying out genomewide identification,characterization and functional analysis of the significantly up-regulated OSCA gene,GhOSCA1.1 through reverse genetics.Result:A total of 35,21 and 22 OSCA genes were identified in G.hirsutum,G.arboreum,and G.raimondii genomes,respectively,and were classified into four different clades according to their gene structure and phylogenetic relationship.Gene and protein structure analysis indicated that 35 GhOSCA genes contained a conserved RSN17 TM(PF02714) domain.Moreover,the cis-regulatory element analysis indicated that the OSCA genes were involved in response to abiotic stress.Furthermore,the knockdown of one of the highly up-regulated genes,GhOSCA1.1 showed that the virus-induced gene silenced(VIGS) plants were highly sensitive to dehydration and salinity stresses compared with the none VIGS plants as evident with higher concentration levels of oxidant enzymes compared with the antioxidant enzymes on the leaves of the stressed plants.Conclusion:This study provides the first systematic analysis of the OSCA gene family and will be important for understanding the putative functions of the proteins encoded by the OSCA genes in cotton.These results provide a new insight of defense responses in general and lay the foundation for further investigation of the molecular role played by the OSCA genes,thereby providing suitable approaches to improve crop performance under salinity and drought stress conditions. | YANG Xiu XU Yanchao YANG Fangfang MAGWANGA Richard Odongo CAI Xiaoyan WANG Xingxing WANG Yuhong HOU Yuqing WANG Kunbo LIU Fang ZHOU Zhongli | 2019 | Journal of Cotton Research2019，2，2： | 7 |
| 19 | Drying characteristics and mathematical model of ultrasound assisted hot-air drying of carrots显示文摘In order to improve the heat and mass transfer process in hot-air drying,power ultrasound was coupled directly to hot-air drying of fresh carrot slices.The effects of ultrasonic power,radiation distance,hot air velocity and temperature on drying characteristics were studied.In addition,the Page equation was used to fit the ultrasound assisted hot-air drying process of the carrot slices.The results showed that the drying rate of carrot slices increased with the increase of ultrasound power and the decrease of radiation distance.Power ultrasound had a greater enhancement on hot-air drying at lower air velocity(0.5 m/s)and temperature(40ºC),especially at the middle and later periods(controlled by internal diffusion).The drying time of carrot slices using ultrasound assisted hot-air drying was shortened by 37.5%compared to that using hot-air drying at the condition with power of 150 W,radiation distance of 15 cm,air velocity of 1.0 m/s and temperature of 40ºC.All test indicators of the model meet the accuracy requirements,which show that the model can better fit the experimental values. | Luo Denglin Liu Juan Liu Yuhong Ren Guangyue | 2015 | International Journal of Agricultural and Biological Engineering2015，8，4： | 6 |
| 20 | Interferon-α salvage treatment is effective for patients with acute leukemia/myelodysplastic syndrome with unsatisfactory response to minimal residual disease-directed donor lymphocyte infusion after allogeneic hematopoietic stem cell transplantation显示文摘The efficacy of salvage interferon-α(IFN-α) treatment was investigated in patients with unsatisfactory response to minimal residual disease (MRD)-directed donor lymphocyte infusion (DLI)(n=24). Patients who did not become MRD-negative at 1 month after DLI were those with unsatisfactory response and were eligible to receive salvage IFN-α treatment within 3 months of DLI. Recombinant human IFN-α-2b injections were subcutaneously administered 2–3 times a week for 6 months. Nine (37.5%), 6 (25.0%), and 3 (12.5%) patients became MRD-negative at 1, 2, and>2 months after the salvage IFN-α treatment, respectively. Two-year cumulative incidences of relapse and non-relapse mortality were 35.9% and 8.3%, respectively. Two-year probabilities of event-free survival, disease-free survival, and overall survival were 51.6%, 54.3%, and 68.0%, respectively. Outcomes of patients subjected to salvage IFN-α treatment after DLI were significantly better than those with persistent MRD without IFN-α treatment. Moreover, clinical outcomes were comparable between the salvage DLI and IFN-α treatment groups. Thus, salvage IFN-α treatment may help improve the outcome of patients with unsatisfactory responses to MRD-directed DLI and could be a potential salvage treatment for these patients after allogeneic hematopoietic stem cell transplantation. | Xiaodong Mo Xiaohui Zhang Lanping Xu Yu Wang Chenhua Yan Huan Chen Yuhong Chen Wei Han Fengrong Wang Jingzhi Wang Kaiyan Liu Xiaojun Huang | 2019 | Frontiers of Medicine2019，13，2： | 6 |
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