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1Current status of preoperative drainage for distal biliary obstruction显示文摘Preoperative biliary drainage(PBD) was developed to improve obstructive jaundice, which affects a number of organs and physiological mechanisms in patients waiting for surgery. However, its role in patients who will undergo pancreaticoduodenectomy for biliary obstruction remains controversial. This article aims to review the current status of the use of preoperative drainage for distal biliary obstruction. Relevant articles published from 1980 to 2015 were identified by searching MEDLINE and Pub Med using the keywords 'PBD', 'pancreaticoduodenectomy', and 'obstructive jaundice'. Additional papers were identified by a manual search of the references from key articles. Current studies have demonstrated that PBD should not be routinely performed because of the postoperative complications. PBD should only be considered in carefully selected patients, particularly in cases where surgery had to be delayed. PBD may be needed in patients with severe jaundice, concomitant cholangitis, or severe malnutrition. The optimal method of biliary drainage has yet to be confirmed. PBD should be performed by endoscopic routes rather than by percutaneous routes to avoid metastatic tumor seeding. Endoscopic stenting or nasobiliary drainage can be selected. Although more expensive, the use of metallic stents remains a viable option to achieve effective drainage without cholangitis and reintervention.Harutoshi Sugiyama Toshio Tsuyuguchi Yuji Sakai Rintaro Mikata Shin Yasui Yuto Watanabe Dai Sakamoto Masato Nakamura Reina Sasaki Jun-ichi Senoo Yuko Kusakabe Masahiro Hayashi Osamu Yokosuka 2015World Journal of Hepatology2015,7,18:11
2Comparison of endoscopic papillary balloon dilatation and endoscopic sphincterotomy for bile duct stones显示文摘Endoscopic treatment for bile duct stones is low-invasive and currently considered as the first choice of the treatment. For the treatment of bile duct stones, papillary treatment is necessary, and the treatments used at the time are broadly classified into two types; endoscopic papillary balloon dilatation where bile duct closing part is dilated with a balloon and endoscopic sphincterotomy(EST) where bile duct closing part is incised. Both procedures have advantages and disadvantages. Golden standard is EST, however, there are patients with difficulty for EST, thus we must select the procedure based on understanding of the characteristics of the procedure, and patient backgrounds.Yuji Sakai Toshio Tsuyuguchi Harutoshi Sugiyama Masahiro Hayashi Jun-ichi Senoo Yuko Kusakabe Shin Yasui Rintaro Mikata Osamu Yokosuka 2016World Journal of Gastrointestinal Endoscopy2016,8,10:6
3Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis by pancreatic duct stenting using a loop-tipped guidewire显示文摘AIM: To examine whether it is possible to prevent the occurrence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis in patients experiencing difficulties with selective biliary duct cannulation by pancreatic duct stenting using a looptipped guidewire.METHODS: Procedure success rate, frequency of unintended insertion of the guidewire into side branches of the pancreatic duct, and incidence of procedural accidents were examined using a loop-tipped guidewire(Group A, 20 patients), and a conventional straighttype guidewire(Group B, 20 patients).RESULTS: The success rate of the procedure was 100% in both groups. Unintended insertion of the guidewire into a side branch of the pancreatic duct occurred 0.056 ± 0.23(0-1) times in Group A and 2.3 ±1.84(0-5) times in Group B; thus, unintended insertion of the guidewire into a side branch of the pancreatic duct was seen significantly less frequently in Group A. There were no procedural accidents in Group A, whereas pancreatitis occurred in one Group B patient; however, the difference between the two groups was not statistically significant. The serum amylase level after ERCP was 257.15 ± 136.4(88-628) IU/L in Group A, and 552.05 ± 534.57(101-2389) IU/L in Group B, showing a significantly lower value in Group A. Hyperamylasemia was found in two patients(10%) in Group A, and nine(45%) in Group B, showing a significantly lower value in Group A.CONCLUSION: The results suggest that in patients who experience difficulties with biliary cannulation, the use of a loop-tipped guidewire for pancreatic duct stenting may assist with the prevention of post-ERCP pancreatitis, and thereby to a reduction of the risk of post-ERCP pancreatitis or hyperamylasemia.Yuji Sakai Toshio Tsuyuguchi Harutoshi Sugiyama Masahiro Hayashi Jun-ichi Senoo Reina Sasaki Yuko Kusakabe Masato Nakamura Shin Yasui Rintaro Mikata Masaru Miyazaki Osamu Yokosuka 2016World Journal of Clinical Cases2016,4,8:5
4HsfAld, a Protein Identified via FOX Hunting Using Thellungiella salsuginea cDNAs Improves Heat Tolerance by Regulating Heat-Stress-Responsive Gene Expression显示文摘Thellungiella salsuginea (先前 T。halophila ) ,种仔细与 Arabidopsis (Arabidopsis thaliana ) 有关,是容忍的不仅高腌层次,而且到寒心,结冰,并且臭氧。这里,我们报导那 T。salsuginea 也比 Arabidopsis 显示出更大的热忍耐。我们识别了 T。作为基因,那能授与的 salsuginea HsfA1d (TsHsfA1d ) 在 Arabidopsis 上标记热忍耐。TsHsfA1d 经由全身的 cDNA 被识别从许多 heat-stress-related T 之中狩猎的过去表示的基因(狐狸) 。salsuginea cDNAs。转基因的 Arabidopsis overexpressing TsHsfA1d 在正常生长温度下面在 Arabidopsis AtHsfA1 regulon 显示出许多基因的组成的起来规定。在 Arabidopsis 叶肉原物, TsHsfA1d 在原子核和细胞质是局部性的。TsHsfA1d 也与 AtHSP90 交往了,它否定地由在细胞质形成 HsfA1HSP90 建筑群调整 AtHsfA1s。TsHsfA1d 的部分原子本地化在正常温度在转基因的植物导致了 AtHsfA1d regulon 的表示,是可能的。我们也发现转基因的 Arabidopsis 植物 overexpressing AtHsfA1d 比野类型的植物更热容忍、起来调整 HsfA1d regulon 的表示在 TsHsfA1d-overexpressing 植物被观察。我们建议 TsHsfA1d 和 AtHsfA1d 的产品作为 Arabidopsis 热压力反应的积极管理者工作并且将为在另外的植物的热压力忍耐的改进有用。Yukari Higashi Naohiko Ohama Tomoko Ishikawa Taku Katori Ayaka Shimura Kazuya Kusakabe Kazuko Yamaguchi-Shinozaki Junko Ishida Maho Tanaka Motoaki Seki Kazuo Shinozaki Yoichi Sakata Takahisa Hayashi Teruaki Taji 2013Molecular Plant2013,6,2:5
5Angiotensin II type 1 receptor-independent beneficial effects of telmisartan on dietary-induced obesity, insulin resistance and fatty liver in mice显示文摘X. Rong Y. Li K. Ebihara M. Zhao J. Naowaboot T. Kusakabe K. Kuwahara M. Murray K. Nakao 2010Diabetologia2010,,8:2
6Coexpression of Escherichia coli RNase III in silkworm cells improves the efficiency of RNA interference induced by long hairpin dsRNAs显示文摘从 chromosomal DNA 抄录的长发卡 dsRNA 能在 Bombyx mori 房间导致 RNA 干扰,尽管它的基因 silencing 效率比外长地介绍的双 stranded RNA (dsRNAs ) 的低。解决这个问题,我们监视了抄录发卡 dsRNA 的原子细胞质的 translocation 并且分析了处理效率进成熟小介入 RNA (siRNA ) 。北污点分析表明抄录发卡 dsRNAs 被拼接并且搬运进细胞质,但是有效地没被用色子赌博进 siRNAs。有趣地,有从染色体综合的红外 transgene 的发卡 dsRNAs 的 RNAi 被 Escherichia coli RNase III 的 coexpression 刺激,尽管这外长的酶似乎引起细胞的 mRNA 的 nonspecific 劈开。Jae Man Lee Yoshito Kojin Tsuneyuki Tatsuke Hiroaki Mon Yoshitaka Miyagawa Takahiro Kusakabe 2013Insect Science2013,20,1:2
7家蚕35K蛋白酶基因的组织表达显示文摘用RT-PCR方法分析了家蚕(Bombyxmori )35K蛋白酶基因在家蚕幼虫期的组织及发育经时性表达。结果表明:35K蛋白酶基因只在幼虫的中肠中部有特异性的表达,在中肠后部有微弱的表达,而在中肠前部及脂肪体、丝腺、精巢、卵巢和血球细胞等组织中不表达;在幼虫期,该基因在中肠组织中的表达量与幼虫摄食活动相关联,认为受该基因控制的35K蛋白酶与营养物质的消化吸收有关,在家蚕的生长发育过程中起重要作用。姜永煌 徐孟奎 Takahiro Kusakabe Hiroshi Fujii 陈玉银 吴玉澄 2002农业生物技术学报2002,10,3:2
8Prepatation and characterization of silica-polyimide composite membranes coated on porous tubes for CO2 separation显示文摘Kusakabe K Ichiki K Hayashi J Macda H Morooka S 1996Journal of Membrane Science1996,115,:1
910Be profiles in sea water显示文摘KUSAKABE M KU T L VOGEL J 1982Nature1982,299,:1
10An encoder-less ultrasonic stepping motor using openloop control system显示文摘Chiharu Kusakabe Yoshiro Tomikawa Takehiro Takano 1992Japanese Journal of Applied Physics1992,31,1:1
11Reoperation for recurrent lumbar disc hemiation:a study over a 20-year period in a Japanese population显示文摘Aizawa T1 Ozawa H Kusakabe T 2012J Orthop Sci2012,17,2:1
12A Numerical Study on Ground Displacement and Stress During and After the Installation of Deep Circular Diaphragm Walls and Soil Excavation显示文摘Yasushi Arai Osamu Kusakabe Osamu Murata 2008Computers and Geotechnics2008,35,:1
13Beneficial effects of leptin on glycaemic and lipid control in a mouse model of type 2 diabetes with increased adiposity induced by streptozoto- cin and a high-fat diet显示文摘KUSAKABE T TANIOKA H EBIHARA K 2009Diabetologia2009,52,4:1
14Thin palladium membrane formed in support pores by metal-organic chemical vapor deposition method and application to hydrogen separation显示文摘Yan S C Maeda H Kusakabe K 1994Ind Eng Chem Res1994,33,3:1
15Steam reforming of tar derived from the steam pyrolysis of biomass over metal catalyst supported on zeolite显示文摘Malinee Kaewpanha Guoqing Guan Xiaogang Hao Zhongde Wang Yutaka Kasai Seiji Kakuta Kastuki Kusakabe Abuliti Abudula 2013Journal of the Taiwan Institute of Chemical Engin2013,,6:1
16Catalytic synthesis of hydrogen peroxide in microreactors显示文摘Maehara S Taneda M Kusakabe K 2008Chemical Engineering Research and Design2008,86,:1
17Structure and expression analysis of the cecropin-E gene from the Silkworm, Bombyx mori 显示文摘Hong S M Kusakabe T Lee J M 2008Biosci Biotech Bioch2008,72,80:1
18Formation of a Y-type zeolite membrane on a porous a-alumina tube for gas separation显示文摘Kusakabe K Kuroda T Murata A Morooka S 1997Industrial and Engineering Chemistry Research1997,36,:1
19Functions of a GnRH receptor heterodimer of the ascidian, Ciona intestinalis 显示文摘Sakai T Aoyama M Kusakabe T 2008Acta Biol Hung2008,59,:1
20Change in Molecular Structure of Flash Pyrolysis Tar by Secondary Reaction in a Fluidized Bed Reactor显示文摘Hayashi J Nakagawa K Kusakabe K 1992Fuel Processing Technology1992,30,3:1
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