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| 1 | Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior显示文摘服的外皮为集成是必要的并且为大多数行为被要求的信息处理。当神经原从室的地区连续地移居联合进特定的外皮的层时,服的外皮的精致地精确的 laminar 组织在胚胎的开发期间产生。当时指南为设计神经原移植责骂的光线的神经胶质行为, pre-formed 脉管的网络为 GABAergic interneuron 移植提供支持和指导暗示。这研究提供新奇概念、机械学的卓见进 vascular-neuronal 相互作用的这个范例,揭示伽马氨基丁酸并且它经由胚胎的前脑 endothelial 房间的调停受体的发信号的新机制。与二个新 endothelial 房间的使用,特定的有条件的老鼠 GABA 小径当模特儿(Gabrb3 Tie2-Cre 和 Vgat 我们显示出的 Tie2-Cre ), 从 endothelial 房间的伽马氨基丁酸版本的那部分或完全的损失在 embryogenesis 期间导致脉管的缺点并且损害长途的移植并且外皮的 interneurons 放。使不安的 endothelial 的下游的效果导出房间的伽马氨基丁酸发信号是批评的,导致上次修改到外皮的电路和坚持的行为的赤字。而且,我们说明在支持他们血大脑障碍性质的迁居, angiogenesis 和获得的前脑 endothelial 房间发信号的伽马氨基丁酸的激活的新机制。我们的调查结果揭开并且阐明在从表明小径的古典 neuronal 伽马氨基丁酸是不同的并且在 neuropsychiatric 疾病的病原学和 pathophysiology 上打开新灯的 CNS 表明小径的新奇 endothelial 伽马氨基丁酸例如孤独性光谱混乱,癫痫,焦虑,消沉和精神分裂症。 | Suyan Li Peeyush Kumar Sampada Joshee Timo Kirschstein Sivan Subburaju Jahan S Khalili Jonas Kloepper Chuang Du Abdallah Elkhal Gabor Szabo Rakesh K Jain Rudiger Kohling Anju Vasudevan | 2018 | Cell Research2018，28，2： | 3 |
| 2 | Effects of temperature, salinity, and dissolved substance on the sorption of polycyclic aromatic hydrocarbons to estuarine particles显示文摘 | Tremblay L Kohl S D Rice J L | 2005 | Mar Chem2005，96，： | 1 |
| 3 | Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis显示文摘 | Sinha P Kohl S Fischer J | 2000 | Electrophoresis2000，21，： | 1 |
| 4 | Optimum dietary protein requirement of a Malaysian freshwater catfish,Mystus nemurus显示文摘 | Khan M S Ang K J Kohl H G | 1993 | Aquaculture1993，112，： | 1 |
| 5 | Novel polymer-ceramic nanocomposite based on high dielectric constant epoxy formula for embedded capacitor application显示文摘 | Rao Y Ogitani S Kohl P | 2002 | J Appl Polym Sci2002，83，5： | 1 |
| 6 | KIT-D816 mutations in AML1/ETO-positive AML are associated with impaired event-free and overall survival 显示文摘 | Schnittger S Kohl TM Haferlach T | 2006 | Blood2006，107，5： | 1 |
| 7 | Developments in the screening for Chlamydia trachomatis 显示文摘 | Kohl K S Markowitz L E Koumans E H | 2003 | Obstet Gynecol Clin North Am2003，30，4： | 1 |
| 8 | New pharmacologic approaches to the prevention of space/motion sickness显示文摘 | MacDonald S | 1991 | J Clin Pharmacol1991，31，9： | 1 |
| 9 | Effects of temperature,salinity,and dissolved humic substances on the sorption of polycyclic aromatic hydrocarbons to estuarine particles显示文摘 | Tremblay L Kohl S D Rice J A | 2005 | Marine Chemistry2005，96，： | 1 |
| 10 | The role of the retinal degeneration slow/peripherin gene in retinal dystrophies显示文摘 | Giddings I Besch D | 1998 | Acta Anat1998，，： | 1 |
| 11 | Unstable bicondylar tibial plateau fractures:a clinical investigation显示文摘 | Eggli S Hartel MJ Kohl S | | 0，，10： | 1 |
| 12 | Photodynamic therapy in dermatology 显示文摘 | Steinbauer JM Schreml S Kohl EA | 2010 | Dtsch Dennatol Ges2010，8，6： | 1 |
| 13 | Are signal time course data useful for differential diagnosis of enhancing lesions in dynamic breast MR imaging显示文摘 | Kohl CK Mielcarek P Klaschik S | 1999 | Radiology1999，211，1： | 1 |
| 14 | An Experimental investigations of microchannel flow with internal pressure measurements 显示文摘 | Kohl M J Abdel-Khalik S I Jeter S M | 2005 | International Journal of Heat and Mass Transfer2005，48，： | 1 |
| 15 | Effects of temperature, salinity and dissolved substances on the sorption of polycyclic aromatic hydrocarbons to estuarine particles 显示文摘 | Tremblay L Kohl S D Rice J L | 2005 | Marine Chemistry2005，96，1： | 1 |
| 16 | Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients显示文摘 | Judith Jacobi Nicholas Bircher James Krinsley Michael Agus Susan S. Braithwaite Clifford Deutschman Amado X. Freire Douglas Geehan Benjamin Kohl Stanley A. Nasraway Mark Rigby Karen Sands Lynn Schallom Beth Taylor Guillermo Umpierrez John Mazuski Holger S | 2012 | Critical Care Medicine2012，，12： | 1 |
| 17 | Electrical conductivity, ionic conductivity, optical absorption, and gas separation properties of ionically conductive polymer membranes embedded with Si micro- wire arrays 显示文摘 | Spurgeon J M Walter M G Zhou J Kohl P A Lewis N S | 2011 | Energy ~ Environmental Science2011，4，： | 1 |
| 18 | Identification of novel proteins associated with the development of chemo resistance in malignant melanoma using two-dimensional electrophoresis显示文摘 | Sinha P Kohl S Fischer J | 2000 | Electrophoresis2000，，21： | 1 |
| 19 | Inhibition of human monocyte-macrophage and lymphocyte cytotoxicity to herpes simplex-infected cells by glucan显示文摘 | Kohl S Pickering LK Diluzio NR | 1979 | J Immunol Methods1979，29，4： | 1 |
| 20 | Molecular basis of an inherited form of incomplete achromatopsia显示文摘 | Trankner D Jagle H Kohl S | 2004 | J Neurosci2004，24，1： | 1 |
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