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21篇 您的检索式:作者名="Kirchner R F"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M 2010Science2010,330,6010:1
3A new mechanism for regional atmospheric chemistry modeling显示文摘STOCKWELL W R KIRCHNER F KUHN M 1997Journal of Physical Research1997,102,25:1
4Iohexol for excretory urography: acomparative study显示文摘Winfield A C Dray R J Kirchner F K etal 1983American Journal Roentgenol1983,141,:1
5Establishment of TEST-yolk buffer enhanced sperm penetration assay limits for fertile males显示文摘Falk R M Silverberg K M Fetterolf P M Kirchner F K Rogers B J 1990Fertil Steril1990,54,1:1
6A development of ozone abatement strategies for the Grenoble area using modeling and indicators 显示文摘Couach O Kirchner F Jimenez R 2004Atmospheric Environment2004,38,10:1
7An intermediate neglect of differential overlap technique for spectroscopy of transition-metal complexes ferrocene显示文摘ZERNER M C LOEW G H KIRCHNER R F 1980J Am Chem Soc1980,102,2:1
8Detection of mitochondrial single nucleotide polymorphisms using a primer elogation reaction on oligonucleotide microarrays 显示文摘 Kirchner R Mann W 2001Nucleic Acids Res2001,29,7:1
9An intermediate neglect of differential overlap technique for spectroscopy of transition-metal complexes ferrocene显示文摘 Loew G H Kirchner R F 1980J Am Chem Soc1980,102,2:1
10Treatment of unstable distal clavicular fractures with and with- out lesions of the acromioclavicular joint 显示文摘HESSMANN M KIRCHNER R BAUMGAERTEL F 1996Injury1996,27,1:1
11Treatment of un-stable distal elavieular fractums with and without lesions of the acromioelavicular joint显示文摘HESSMANN M KIRCHNER R BAUMGAERTEL F 1996Injury1996,27,1:1
12Influence of fluorine on the solubility of manganotantalite(MnTa20e) and manganocolumbite (MnNb206) in graniticmelts: An experimental study显示文摘Fiege A Kirchner C Holtz F Linnen R L Dziony W 2011Lithos2011,122,34:1
13An intermediate neglect of differential overlap technique for spectroscopy of transition-metal complexes ferrodene显示文摘Zerner M C Loew G H Kirchner R F 1980J Am Chem Soc1980,102,2:1
14Treatment of un- stable distal clavicular fractures with and without lesions of the acromio-claviculer joint显示文摘Hessmann M Kirchner R Boumgaetel F 1996Injury Int J Care Injured1996,27,:1
15Detection of mitochondrial single nucleotide polymorphisms using a primer elogation reaction on oligonucleotide microarrays 显示文摘ERDOGAN F KIRCHNER R MANN W 2001Nucleic Acids Research2001,29,:1
16Treatment of un- stable distal clavicular fractures with and without lesions of the acromioclavicular joint显示文摘Hessmann M Kirchner R Baumgaertel F 1996Injury1996,27,1:1
17Sulfur isotope dynamics in two Central European watersheds affected by high atmospheric deposition of SOx 显示文摘Novak M Kirchner J W Groscheova H Havel M Cerny J Krcei R Buzek F 2000Geochim Cosmochim Acta2000,64,3:1
18Treatment of carcinoma of the penis:the case for primary lymphadenectomy显示文摘McDougal W S Kirchner F K Jr Edwards R H 1986J Urol1986,136,1:1
19A new mechanism for regional atmospheric chemistry modeling显示文摘STOCKWELL W R KIRCHNER F KUHN M 1997Journal of Geophysical Research1997,,25:1
20Treatment of carcinoma of the penis: the case for primary lymphadcnectomy显示文摘McDougal W S Kirchner F K Jr Edwards R H 1986J Urol1986,136,1:1
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