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	题名	作者	年代	出处	被引量
1	Effect of Commiphora mukul gum resin on hepatic marker enzymes,lipid peroxidation and antioxidants status in pancreas and heart of streptozotocin induced diabetic rats显示文摘Objective:To study the antioxidant efficacy of Commiphora mukul(C.mukul) gum resin ethanolic extract in streptozotocin(STZ) induced diabetic rats.Methods:The male Wistar albino rats were randomly divided into four groups of eight animals each:Control group(C),CM-treated control group(C_+CMEE),Diabetic control group(D),CM- treated diabetic group(D_+CMEE).Diabetes was induced by intraperitoneal injection of STZ(55 mg/kg/ bwt).After being confirmed the diabetic rats were treated with C.mukul gum resin ethanolic extract(CMEE) for 60 days.The biochemical estimations like antioxidant,oxidative stress marker enzymes and hepatic marker enzymes of tissues were performed.Results:The diabetic rats showed increased level of enzymatic activities aspartate aminotransaminase(AST),alanine aminotransaminase(ALT) in liver and kidney and oxidative markers like lipid peroxidation(LPO) and protein oxidation(PO) in pancreas and heart. Antioxidant enzyme activities were significantly decreased in the pancreas and heart compared to control group.Administration of CMEE(200 mg/kg bw) to diabetic rats for 60 days significantly reversed the above parameters towards normalcy.Conclusions:In conclusion,our data indicate the preventive role of C.mukul against STZ-induced diabetic oxidative stress;hence this plant could be used as an adjuvant therapy for the prevention and/or management of diabetes and aggravated antioxidant status.	Ramesh B Karuna R Sreenivasa Reddy S Haritha K Sai Mangala D Sasi Bhusana Rao B Saralakumari D	2012	Asian Pacific Journal of Tropical Biomedicine2012，2，11：	3
2	Inhibition of shrimp pathogenic vibrios by a marine Pseudomonas Ⅰ-2strain显示文摘	CHYTHANYA R KARUNA SAGAR I	2002	Aquaculture2002，208，：	1
3	Protective effects of Phyllanthus amarus aqueous extract against renal oxidative stress in Streptozotocin-induced diabetic rats 显示文摘	Karuna R Bharathi V G Reddy S S	2011	Indian J Pharmacol2011，43，4：	1
4	Progress of advanced composites for civil infrastructure显示文摘	CANNING L HODGSON J KARUNA R	2007	Proceed- ings of the Institution of Civil Engineers Structures & Build- ings2007，160，6：	1
5	Cost-effectiveness of laparoscopy versus iaparotomy for initial surgical evaluation and treatment of potentially resectable hepatic colorectal metastases:a decision analysis显示文摘	Karuna ST Thirlby R Biehl T	2008	J Surg Oncol2008，97，5：	1
6	Antioxidant potential of aqueous extract of Phyllanthus amarus in rats显示文摘	Karuna R Reddy SS Baskar R	2009	Indian J Pharmacol2009，41，：	1
7	Monitoring of Structures Using the Global Positio- ning System显示文摘	BROWN C J KARUNA R ASHKENAZI V	1999	Proceedings of the Institution of Civil Engineers- structures and Buildings1999，134，1：	1
8	Linking innovation process to the provisioning of public goods:The case of neglected diseases显示文摘	Shishir K.Jha Mukundan R Karuna Jain		0，，：	1
9	Plasma levels of sphingosine-1-phosphate and apolipoprotein M in patients with monogenic disorders of HDL metabolism显示文摘	Karuna R Park R Othman A	2011	Atherosclerosis2011，219，2：	1
10	Drug utilization study in a burn care unit of a tertiary care hospital显示文摘	Santoshkumar R Jeevangi RB Patil SM Awanti S Manjunath Basavaraj Patil Karuna Devi	2011	Asian Pacific Journal of Tropical Disease2011，，1：	1
11	Self - organized ZnA12 04 nanostructures grown on c - sapphire 显示文摘	JUSTINA GRABOWSKA KARUNA KAR NANDA R T RAJEN- DRA KUMAR	2007	Superlattices and Microstructures2007，42，：	1
12	Epidemiology of spasticity following traumatic spinal cord injury显示文摘	Maynard F Karunas R Waring 3RDW	1990	Arch Physical Med Rehabil1990，8，：	1
13	Li- pase - catalyzed preparation of palmitic and stearic acid - rich phosphatidylcholine显示文摘	REDDY J R C VIJEETA T KARUNA M S L	2005	J Am Oil Chem Soc2005，82，10：	1
14	Lipase-eata/yzed preparation of palmitie and stearic acid-rich phosphatldylcholine 显示文摘	J R C Reddy T Vijeeta M S L Karuna	2005	JAOCS2005，82，10：	1
15	Linking innovation process to the provisioning of public goods: The case of neglected diseases 显示文摘	Shishir K Jha Mukundan R Karuna J	2010	The Innovation Journal: The Public Sector Innovation Journal2010，15，2：	1
16	Estrogen receptor expression in adenomyosis-Does it shed a light on pathogenesis显示文摘	Lillian T Karuna R	2000	Fertility and Sterility2000，9，1：	1
17	Use of ion-exchange chromatography coupled with TLC-Iaser scanning densitometry for the quantizationof fumonisin B1显示文摘	Karuna R Sashidhar RB	1999	Talanta1999，50，2：	1
18	Plasma levels of sphingo- sine-1-phosphate and apolipopmtein M in patients with monogenic disorders of HDL metabolism 显示文摘	Karuna R Park R Othman A	2011	Atherosclerosis2011，219，2：	1
19	Linking innovation process to the provisioning of public goods: The case of neglected diseases显示文摘	Shishir K J Mukundan R Karuna J	2010	The Innovation Journal: The Public Sector Innovation Journal2010，15，2：	1
20	Preventive effect of tinospora cordifolia against high- fructose diet-induced insulin resistance and oxidative stress in male Wistar rats 显示文摘	Reddy S S Ramatholisamma P Karuna R	2009	Food Chem Toxicol2009，47，9：	1

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